Pilonidal Sinus PNS affects young people presenting as chronic sinuses and more frequently as acute abscess. Even after excision of the sinus a number of patients will have recurrence and need a second operation. The problem is caused by a prolonged and sustained presence of high level of sex hormones in the circulation (androgen) causing continuous stimulation of a special sweat glands at the buttock area, the excess sweat produced contain a positively charged electrolytes which attract the negatively charged hairs (by friction) to dive in to the widely opened orifices of these glands resulting in their acute inflammation and chronic sinus formation on the long term. If the circulating androgen level is reduced, the excess sweat secretion come to normal, the opened orifices of the sweat glands close, and the whole process of inflammation and abscess formation come to an end. INTRODUCTION Evidence available suggests that some of the tubular glands are controlled by hormones, in rabbit all three apocrine glands are stimulated by androgen, the human apocrine glands of the axillary and pubic region are similarly under androgen control (1). In men sexual stimulation by visual, auditory and olfactory pathways through the hypothalamuspituitarytesticular axis act to increase sexual desire by elevating the circulating androgen level (2) which have an effect on the sex organs in particular and on the body as a whole including the sweat glands (resulting in their stimulation and increased secretion). There are special sweat glands at the buttock (Sudoreferous glands), such glands being more active in early manhood, these glands in some animals secret odoureferous substances during rutting season to attract opposite sex (4). These glands are under androgen stimulation and when the circulating androgen level is high the secretion of these glands increases, resulting in excess sweating in the buttock area. This sweat contain excess electrolytes, the composition of sweat varies greatly from person to person, time and site. The sweat is hypo tonic, the most important constituents of the sweat are Na, K (positively charged),& Cl, also urea & lactose (1). The broken hairs in the cleft will have a negative charge by friction, which will be attracted by the positively charged sweat electrolytes to dive in to the open orifice of the sweat glands to start the process of inflammation and abscess formation. The holes or pits seen at the buttock represent a distorted hair follicles and sweat glands openings that have enlarged under the continuous and prolonged stimulation effect of the high level circulating androgen. These enlarged hair follicles and sweat glands open mouths or pits appear first then the ingested hairs is secondary invader that start the process of acute inflammation and on the long term prolong the disease and interfere with healing, no hair follicle have ever been found in the sinus tract, this observation provided an early clue that hair found therein was of extraneous origin (2).. The way these broken hairs seen packed in to these tiny pits can not be explained but by this electric attraction mechanism. MATERIAL Two groups of patients were studied THE FIRST GROUP A retrospective review of files of patients with PNS treated by a colleague general surgeon (Dr Jalil), since his arrival at the hospital up to the start of the second group which is over Pilonidal Sinus And Prolonged Sexual Stimulation: The Poisonous Hormones 2 of 5 a year now, when we started looking at a new way of treating patients with PNS. There were 23 patients with mean age of 19.7 years 20 males, 18 single 2 married 3 females 2 single 1 married