Working Time Research Articles

Radiological safety assessment of monazite industry worker due to NORM inhalation.

Monazite is used as a raw material for the production of rare earth elements. The workers in the monazite industry are exposed to radiation from the raw material. Therefore, internal radiation dose should be assessed for radiological safety assessment of the workers. The objective of this study is to assess the internal radiation dose to workers of the monazite industry in Korea by means of measured particulate. Particulate properties, including size distribution, density, shape, and radioactivity concentration were analyzed. Then, the internal radiation dose coefficients were derived using the IMBA software. Work scenarios were derived by identifying the work time. Finally, internal radiation doses were calculated with the collected and calculated data. The internal radiation dose ranged from 7.48×10-3 to 3.25×10-1mSv y-1 with dose difference by orders of magnitude. It is highlighted why such data should be directly collected at sites to realistically assess radiation dose to workers.

A comprehensive analysis of time investment in skid trail planning for forest access.

Properly planned skid trails form an important basis for sustainable timber production. They affect cost-effectiveness and the environmental impact of the harvesting process to a large extent. Here, we conducted an economic analysis to understand the skid trail planning process and to generate an initial model to estimate the time and costs involved. We investigated in detail how the planning process of skid trails is carried out in practice, what time is required for the planning work, and what factors influence its performance. Through an online survey conducted in 2022, we asked practitioners in Germany and Switzerland about their time and effort required for the planning process and the determining factors, such as the planning method and the terrain and stand conditions. Based on this survey, we calculated statistical indicators of time consumption, considered possible rationalization options, and developed an initial estimation model. The effort required to identify and evaluate skid trails planned for distances of 20 to 40 m amounts to around 3 to 4 hours of productive working time per hectare, with deviations expected depending on the specific situation in the forest. The costs corresponding to this investment amount to less than one euro per cubic meter of harvested timber, depending primarily on the extent of wood use. Our in-depth insight into the planning process enables its economic evaluation and the development of improvements.

Factors Related to Worker Performance at PMI South Jakarta City in 2024

Worker performance is a necessary factor in the progress of an agency. It is known that there are workers who show less than optimal performance at PMI South Jakarta City, so it is necessary to know what the factor in the lack of performance produced. This research aims to determine the elements related to worker performance in PMI South Jakarta City in 2024. This research uses a cross-sectional study design and analysis using the chi-square test. Sampling used a purposive sampling technique with a minimum sample of 60 respondents. The research instruments used include NASA – TLX, MWMS, DOCS, and IWPQ. The results show that organizational culture (p = 0.011), motivation (p = 0.022), workload (p = 0.008), and working time (p = 0.041) have a relationship with employee performance. Meanwhile, age (p = 0.362), gender (p = 0.899), last education (p = 0.940), marital status (p = 0.090), length of service (p = 0.355), and job content (p = 0.455) showed no there is a relationship with worker performance. Agencies are advised to set equal working hours by regulations and implement a reward system to increase worker motivation.

High levels of heat stress among sugarcane workers in Thailand.

With continued global warming, the effects of elevated temperatures on the health of agricultural workers are a particular concern. This study characterized the levels of heat stress in Thai sugarcane workers and investigated whether season and harvesting method were associated with it. Three hundred sugarcane workers in Nakhon Sawan Province, Thailand, were recruited, and information on demographics, working conditions, and clothing characteristics was collected from participants during the cooler months (n = 152 participants, mid-January to mid-February) and hotter month (n = 148, March). Heat stress was measured using the Wet Bulb Globe Temperature (WBGT) index, and the WBGT instruments were operated for a full work shift in the sugarcane fields where the participants worked. One-hour time weighted average (TWA) effective WBGT (WBGTeff-1hrTWA) estimates were determined for different times of the day based on the measured WBGT and clothing adjustment factor. The average WBGTeff-1hrTWA in the cooler months ranged from 22.5 °C during the early morning to 31.3 °C during the hottest time of the day, and for the hotter month, it ranged from 25.4 °C to 33.9 °C, respectively. The measured WBGT, natural wet-bulb temperature (Tnwb), dry-bulb temperature (Tdb), globe temperature (Tg), air velocity (Av), and absolute water vapor pressure (ea) were all statistically significantly higher in the hotter month than in the cooler months. Harvesting during the hotter month and harvesting burnt sugarcane were significantly associated with increased effective WBGT. The harvesters' heat stress in both seasons exceeded the American Conference of Governmental Industrial Hygienists - Threshold limit value for 72.7% of the working time in the cooler months and 90.9% in the hotter month. The heat stress in Thai sugarcane workers was high in both seasons, particularly in the hotter month and when harvesting burnt sugarcane. This results in a very high risk of developing heat-related health effects, and measures are needed to reduce heat stress. Heat stress in agricultural and other outdoor work in tropical climates is an immediate and growing problem.

Applicability of Artificial Intelligence Analysis in Oral Cytopathology: A pilot study.

Oral cancer, especially oral squamous cell carcinoma (OSCC), is a global health challenge due to factors such as late detection and high mortality rates. Early detection is essential through monitoring by healthcare professionals. Cytopathology is a cellular analysis model for evaluating cellular damage preceding the clinical appearance of OSCC, but it requires training and has diagnostic limitations, due to its subjective aspect. Artificial Intelligence (AI) shows potential to enhance the interpretation of cytological images, reducing working time and subjectivity. To compare the effectiveness of human analyses versus AI system assessment of oral cell smears stained by the Papanicolaou technique. The study comprised 57 patients in Porto Alegre - RS divided into four groups: Control Group (CG), Exposed Group (EG), Oral Potentially Malignant Disorders Group (OPMDG), and OSCC Group (OSCCG). Cytopathological smears were collected from the border of the tongue of CG and EG and from the lesional area in OSCCG and OPMDG. The Papanicolaou technique was performed according to standard protocol, with morphological analysis. Images were analyzed by two human examiners as well as by an AI system (Papanicolaou Slide Image Examiner - PSIE). Concordance between human and PSIE was good. The proportion of cytological findings between human and PSIE was similar and the analysis time of PSIE was 16.6 times shorter than that of human researchers. The use of AI for OSCC screening is promising and demonstrated to be a suitable tool for routine use mainly with the advance of IA-human concordance analysis and serving as a tool to accelerate the analytical process.

Real time monitoring of Rn-222 in workplaces and estimation of working time correction factor

The potential of electronic monitors for evaluating radon exposure is still not fully harnessed, and tests under real conditions are scarce. Ten workplaces were continuously monitored for a year with the radon measurement network of Sofia University, with calibrated and metrologically assured RadonEye +2 monitors. In 7 of the workplaces the average activity concentration of radon during the working time was significantly lower than the total time average. This difference is attributed to behavioral patterns. The ratio of the working time and the total time average (called working time correction factor kWT) for the whole year ranged from 0.71 to 0.98. Its weekly values varied significantly with coefficients of variation between 9 and 28%. Therefore, using short term estimates of kWT to correct the total time radon average determined by passive detectors could lead to bias.The workplaces also exhibited different seasonal radon patterns, although most were offices with similar schedules. In most pairs of workplaces the monthly averages were correlated very weakly or even negatively. This indicates that seasonal radon variations could be specific to each workplace. The value of kWT also varied with the season, suggesting that seasonal variations of radon during working hours might differ from those observed with passive integrating detectors.Overall, long-term follow-up by metrologically assured electronic monitors could help to improve and personalize the estimate of radon exposure of workers. These monitors could potentially support smart anti-radon systems with optimal operation schedules, thereby contributing to the reduction of the energy impact of buildings.

Data on the administrative workload and perceived administrative burden of farmers in Switzerland

We present data from a paper-and-pencil survey of Swiss farmers. The survey was mailed to 2,000 randomly selected Swiss farmers from the two largest Swiss language regions (German and French) in February 2019. A reminder was sent in April 2019. The response rate was around 40% (N = 811). In the main part of the survey, we collected quantitative data on farmers’ workload and perceived burden due to (1) overall farming activities, (2) administrative activities related to the application of direct payments, and (3) other office work related to farm planning, bookkeeping, purchasing, and sales. We also asked farmers to rate their current workload and perceived administrative burden compared to five years earlier. We also collected data on the perceived burden of using e-government services, the administrative workload of various voluntary direct payment schemes, and the workload of inspections and sanctions. We collected personal information about the farmers. Finally, the farmers were asked to rate a series of statements regarding agricultural policy measures, the importance of inspection measures, the obligation to provide proof of eligibility for direct payments, information on current policy measures, and the justification of penalties for non-compliance with environmental or animal welfare standards. The survey results showed that, on average, Swiss farmers spent 3–5% of their total working time on administrative tasks. The farmers rated the perceived burden of administrative activities as higher than the burden of overall farming activities or other office work. The data also showed that the farmers’ perceived administrative burden had increased compared to five years earlier. Finally, the results showed that 28% of the Swiss farmers had received a penalty for non-compliance with direct payment regulations.

Features of the work activity and health status in station and shunting dispatchers at the railway transport

Introduction. One of the urgent problems of occupational hygiene is the optimization of working conditions and the protection of the health in workers at the railway transport. Technical progress at the railway transport, the introduction of modern automation tools, and the gain in the operational capacity of railways place special requirements for such occupations referred to the group of dispatching and operator occupations. One of the leading occupations among this category of workers is the profession of station and maneuver dispatchers. Chronic exposure to nervous and emotional stress in station and maneuver dispatchers can contribute to the development of pathological conditions in various organs and systems of the body and cause corresponding diseases. Therefore, an in-depth study of the working conditions of station and shunting dispatchers is relevant and timely. The purpose of the study to investigate the working conditions in station and shunting dispatchers of the railway transport with the development of preventive measures. Materials and methods. Time-lapse studies were carried out (photo of the working day). Measurements of harmful production factors in the workplace were carried out using the method of special assessment of working conditions. The structure of morbidity has been studied. Results. According to the conducted research, it was found that the duration of concentrated attention for shunting dispatchers is 93.3%, for station dispatchers 87.7%. The average signal density per hour is 304 for the station dispatcher, and 311 for the maneuvering dispatcher. The load on the organs of hearing and vision was established. The hearing load for station dispatchers was 4–8 hours, for maneuver dispatchers – 5–7 hours, including talking on the “phone” and “selector”. During the work of the dispatcher, complex tasks are solved with a choice according to known algorithms (work according to a series of instructions), which takes 73.5–79.3% of the working time for station dispatchers, 70.8–96.3% for maneuvering dispatchers. Morbidity rates with temporary disability in the above-mentioned occupations are much higher than the industry average. Limitations. Stations and branches were selected as the basic facilities for conducting hygienic research at the Moscow, Oktyabrskaya, and Sverdlovskaya railways. Conclusion. The work activity in station and maneuver dispatchers is characterized by a significant amount of work, including speech (semantic), signal (auditory), sign and visual information. This allows characterizing it as operator labour against the background of a high degree of stress factors. According to the indicators of the intensity of the labour process, the working conditions in station and maneuver dispatchers are classified as strenuous work of the 3rd grade of harmfulness, class 3.3. Employees of this occupation category have a high incidence of temporary loss of ability to work in terms of the number of cases of disability of 149.0 and the number of days of disability of 1,800, 8 per 100 employees. The average duration of the one case is 12.1 days. Based on the conducted research there were developed preventive recommendations, including rehabilitative psychohygienic means, and methods of improving the health in operator personnel and knowledge workers.

Study on the cooling effect of the parallel perforated ventilation subgrade in permafrost regions based on the numerical model.

The runway in permafrost regions has remarkable temperature sensitivity. Therefore, this paper puts forward to the parallel perforated ventilation subgrade. The reliability and validity of the finite element model of the runway with the parallel perforated ventilation subgrade are verified by comparing with the previous studies. And the cooling effect of the parallel perforated ventilation subgrade is analyzed. Results show that the parallel perforated ventilation subgrade has a significant cooling effect on the pavement and has little cooling effect in the natural ground. Compared with the non-ventilation subgrade, temperature time-history curves for the parallel perforated ventilation subgrade change periodically each year and are gradually lower with the growth of time. Temperature-depth curves for the parallel perforated ventilation subgrade change significantly at the insulation layer, the crushed rock layer, and the perforated ventilation. The air velocity and working time of the parallel perforated ventilation have no effect on the temperature of the surface layer, base layer, and subbase layer, have little effect on the temperature of the insulation layer, and have great effect on the temperature of the crushed rock layer and subgrade. This study provides scientific support for the design, construction, and maintenance of the runway in permafrost regions.

Swarms can be rational.

The emergence of collective order in swarms from local, myopic interactions of their individual members is of interest to biology, sociology, psychology, computer science, robotics, physics and economics. Cooperative swarms, whose members unknowingly work towards a common goal, are particularly perplexing: members sometimes take individual actions that maximize collective utility, at the expense of their own. This seems to contradict expectations of individual rationality. Moreover, members choose these actions without knowing their effect on the collective utility. I examine this puzzle through game theory, machine learning and robots. I show that in some settings, the collective utility can be transformed into individual rewards that can be measured locally: when interacting, members individually choose actions that receive a reward based on how quickly the interaction was resolved, how much individual work time is gained and the approximate effect on others. This internally measurable reward is individually and independently maximized by learning. This results in a equilibrium, where the learned response of each individual maximizes both its individual reward and the collective utility, i.e. both the swarm and the individuals are rational.This article is part of the theme issue 'The road forward with swarm systems'.

Action research at the BBC: Interrogating artificial intelligence with journalists to generate actionable insights for the newsroom

In this paper, we provide reflections from an embedded action research project undertaken at the UK’s largest public service broadcaster, the BBC, over a three-year period. It was aimed at eliciting research insights about the role and understanding of AI in news production and also intervening to engender change in the newsroom. We surface the messy realities of conducting this work, including the challenges to funding such long-term and resource-intensive research and the difficulties of measuring impacts. We include practical guidance to demystify the process of action-oriented research that strives for targeted change in news contexts, highlighting the need for researchers to cost in time for translational work and the importance of having ‘critical friends’ to hold them to account. Ultimately, we emphasise the value of action research in journalism studies and particularly at the nexus of news and technology. We argue for approaches that retain a critical perspective whilst closing the gap between theory, critique, and practice.

A Microsimulation Model for Sustainability and Detailed Adequacy Analysis of the Retirement Pension System

The sustainability and adequacy of pension systems are central to public policy debates in aging societies. This paper introduces a novel microsimulation model with probabilistic behavior to assess these dual challenges in the Spanish pension system. The model employs a mixed-projection method, integrating a macro approach—using economic and demographic aggregates from official sources such as the Spanish Statistics Office (INE) and Eurostat—with a micro approach based on the Continuous Sample of Working Lives (MCVL) dataset from Spanish Social Security. This framework enables individual-level projections of key labor market variables, including work time, salary, and initial pensions, under diverse reform scenarios. The results demonstrate the model’s ability to predict initial pensions with high accuracy, providing detailed insights into adequacy by age, gender, and income levels, as well as distributional measures such as density functions and quantiles. Sustainability findings indicate that pension expenditures are projected to stabilize at 13.9% of Gross Domestic Product (GDP) by 2050. The proposed model provides a robust and versatile tool for policymakers, offering a comprehensive evaluation of the long-term impacts of pension reforms on both system sustainability and individual adequacy.

Three-Dimensional-Printed Elements Based on Polymer and Composite Materials in Dentistry: A Narrative Review

Abstract 3D printing technologies are manufacturing technologies based on computer-designed digital models that allow fabrication of layered three-dimensional objects. This review aims to present a summary of the literature published on 3D-printed polymer and composite materials in dentistry. A literature search was performed using the PubMed database to identify eligible articles. In total 508 articles were identified based on the original search query, with 362 being eliminated based on the exclusion criteria and 146 articles were screened and based on their abstracts, 68 articles were studied in detail. Subsequently, these articles were divided into three groups based on the area of application: (1) restorative dentistry, which included 3D printed crowns, bridges, and veneers; (2) regenerative dentistry and tissue engineering, such as 3D printed scaffolds; (3) fabrication of oral guides and other appliances, such as surgical guides, dental implants, and surgical splints. In this review the 3D printing technology is described, including its benefits regarding working time, accuracy and overall design and fabrication of products. The review shows that the most studied area of application of printable polymers and composites is regenerative dentistry. Even though these materials are studied for their properties and the effects on the human body as well as the environment, novel materials with specific and revolutionary characteristics that have emerged in recent years are given special attention. However, more research is needed to ensure the safety of use and confirm the characteristics of novel materials in both in vivo and in vitro conditions.

“More Attentive to My Wellness”: Reported Experiences of Academic Nurse Faculty and Staff in the Early Months of the Pandemic

The COVID-19 pandemic presented major changes for individuals working in nursing academia. While university faculty and staff encountered many challenges, the pandemic also presented new opportunities. The purpose of this study was to determine how the early months of the COVID-19 pandemic impacted nursing faculty and staff perceptions about their wellness experiences. An on-line survey was developed and sent to all faculty and staff. Data were collected through a convenience sample using both open-ended and closed-ended questions. Descriptive statistics and qualitative content analysis were used to analyze the data. Among respondents (n = 139), wellness areas frequently reported to be “better” included productivity, access to meetings, work time flexibility, work-day attire, feeling respect and understanding from colleagues, nutrition, physical activity, and outdoor time. Areas frequently reported to be “worse” included workspace ergonomics, opportunities for informal check-ins, connectivity, and collaboration with colleagues, length of the workday, perceived work-life balance, sleep, mood, and connectivity with friends/family. Key themes emerged from coded open-ended responses; these include flexibility, self-care, connection, and leadership support. Examples of both positive and negative experiences are contained within each code and respective theme. Opportunities for continued flexibility and compassion for differing experiences were commonly observed in the survey and were recommended for retention post-pandemic to promote employee well-being. Open communication and transparency were also suggested as key elements required for successful transition in the return to routines as the pandemic becomes endemic. The implications of these findings may be extended to broader crises.

Improvement of diagnostic approachesfor reliability management of agricultural machinery

Reducing life cycle costs, optimizing operating costs and timely maintenance, carrying out work within the required agricultural timeframes are indicators of the eff ectiveness of optimal management of the reliability of agricultural machinery. In turn, a signifi cant impact on reliability management is exerted by the degree of improvement of approaches to adaptability to maintenance and diagnostics, taking into account the use of digital monitoring tools for resource-determining components and assemblies. Effective implementation of reliability management will allow minimizing costs from the consequences of failures of complexity groups II and III, reducing the cost of production and adjusting the time of service work based on an analysis of the dynamics of changes in the actual technical condition. Therefore, improving approaches to carrying out routine work, including diagnostics, is a pressing issue for increasing the effi ciency of domestic equipment in use. Conduct an analysis of technical condition assessment approaches previously used to manage the reliability of agricultural machinery and develop experimental samples of digital diagnostic tools to improve the assessment of technical condition. We examined the process of creating experimental digital diagnostic tools to improve approaches to reliability management, regulated by the methodological recommendations of the scientifi c and technical documentation and the goals of the project of the Ministry of Agriculture of the Russian Federation "Digital Agriculture". It was showed that when searching for approaches to diagnostics for reliability management, it is necessary to take into account that previously produced diagnostic tools were developed and widely used under the organized VO "Selkhoztekhnika". They indicated that at present it is necessary to take into account methodological experience that makes it possible to increase the level of diagnostics of operating equipment on the basis of new multifunctional diagnostic tools that allow monitoring the assessment of technical condition. We have developed experimental digital means for monitoring technical condition, allowing for monitoring the technical condition and compliance with operating rules of individual systems and units. It was revealed that the use of digital diagnostic and monitoring tools makes it possible to reduce the cost of the life cycle of equipment, optimize operating costs, and allows for maintenance to be carried out based on the actual condition to prevent failures.

Technological anthropocentrism in accounting for Industry 5.0

Introduction. The emergence of the Fifth Industrial Revolution emphasizes technological anthropocentrism as a concept for managing enterprises based on accounting information and leveraging advanced computer-communication technologies. Industry 5.0 focuses particularly on the critical role of modern computer-communication technologies in realizing anthropocentric priorities within the societal framework, particularly in the financial and economic activities of enterprises. The purpose of the article is to position the anthropocentric concept of enterprise management based on accounting information as an informational component of Industry 5.0, utilizing state-of-the-art computer-communication technologies. Methods. The study of accounting transformation prospects in the context of Industry 5.0 employed general scientific empirical, logical, and historical methods of cognition. The research is based on general methods of analyzing economic processes, facts, and phenomena from the perspectives of accounting and computer technologies. Results. It is substantiated that technological anthropocentrism is becoming a key concept in enterprise management, grounded in the implementation of opportunism, behaviorism, agency theory, and institutionalism. The main directions for implementing anthropocentrism in Industry 5.0 accounting include adherence to robotics laws, optimization of working time, stimulation of creativity, professional development, and meeting stakeholders’ informational needs. It is noted that technological anthropocentrism contributes to mitigating informational, reputational, and socio-economic risks while supporting the socio-economic interests of society, professionals, and state institutions. Prospects. The process of establishing technological anthropocentrism is ongoing and multifaceted, highlighting new aspects of accounting transformation in the context of the development of innovative computer-communication technologies. This necessitates further research in the realm of Industry 5.0.

Exploring the Coexistence Between New Quality Productive Force Developments, Human Capital Level Improvements and Time Poverty from a Time Utilization Perspective

The development of new quality productive forces and the improvement of human capital have significantly improved people’s material and spiritual living standards. However, this has not brought people time affluence. Time poverty is related to lower happiness and physical health, and should be of concern. This paper theoretically analyzes the relationship among new quality productive forces, human capital level and time poverty, and conducts an empirical study based on the data from the Residents’ Life Time Allocation Survey from 2006 to 2021. The results show that more than 40% of individuals feel time poverty. Under the combined influence of new quality productive forces and human capital level, individual work time is still increasing, while leisure time is decreasing, which has contributed to increased time poverty. Individuals participate in more leisure activities in less leisure time, so they do not fully enjoy their leisure time. Moreover, with the improvement of new quality productive forces and human capital level, individuals are more inclined to participate in cultural appreciation, educating children, amateur learning, etc., activities. These activities are more like the extension of work time, so that people feel that leisure time is dominated. All these effects are significantly different in terms of gender, marital status, occupation, family size and income.

A Workload Indicators of Staffing Need (WISN) based framework and implementation tool for dietitians at South African central and tertiary public hospitals

BackgroundQuality nutrition services are dependent upon the accessibility and availability of nutrition professionals. In this study, we used the World Health Organization’s Workload Indicators of Staffing Need (WISN) methodology to develop a dietetic staffing norm framework and implementation tool for South African central and tertiary public hospitals.MethodsWe followed the eight step WISN methodology as a basis for this developmental study. National data on permanently employed dietitians in public hospitals were used to determine the facility type. Available working time (AWT) was determined using WISN calculations and SA labour regulations. Consensus on workload components (WC) and activity standards (AS) was achieved through a Delphi exercise. Steps 5 to 8 ended in determination of dietitian requirements based on WISN software. Similar steps were used to develop the framework and tool. The tool’s calculated outputs were compared against the WISN software.ResultsCentral and tertiary public hospitals were identified as the target facilities. Dietitians AWT at these facilities was calculated as 1528 h per year. A final list of 45 WC and aligned AS was obtained and provided the necessary contextualization. A WISN based framework, and a Microsoft Excel tool (calculator) resulted. Calculated average dietitians’ requirements were 24.59 and 24.23 for WISN software and the excel tool respectively.ConclusionThe WISN methodology is a versatile tool that allows for the development of context and cadre specific staffing norm implementation frameworks and tools. The developed tool is valid and contextualized to determine the specific need for dietitians at SA central and tertiary public hospitals. These results will help policy makers to plan and forecast dietetic staffing needs at a macro level.

Comparisons of Physicians', Nurses', and Social Welfare Professionals' Experiences With Participation in Information System Development: Cross-Sectional Survey Study.

The integration of health care and social welfare services together with the consolidation of health care information systems (HISs) and client information systems (CISs) has become a timely topic. Despite this development, there is a scarcity of systematic research on physicians', registered nurses' (RNs) and social welfare professionals' (SWPs) experiences of participating in the development of HISs and CISs. This study aimed to examine how physicians, RNs and SWPs experience collaboration with HIS or CIS vendors, and what kinds of end users have participated in HIS or CIS development. National cross-sectional usability surveys were conducted in Finland among RNs and SWPs in 2020 and physicians in 2021. Questions concerning participation experiences were analyzed by professional group, working sector, managerial position, and age. In total, 4683 physicians, 3610 RNs, and 990 SWPs responded to the surveys. In all 3 professional groups, those working in nonmanagerial positions and the youngest respondents participated least in HIS or CIS development, and 76% (n=3528) of physicians, 78% (n=2814) of RNs and 67% (n=664) of SWPs had not participated at all. When comparing the groups, physicians were least aware of feedback processes and least satisfied with vendors' interest in end-user feedback and the manner and speed of HIS development. Those who had dedicated working time for HIS or CIS development were less critical of vendors' interest and responsiveness to development ideas than those who had not participated at all. In all 3 professional groups, the youngest were most dissatisfied with HIS and CIS vendor collaboration. Experiences of participation in HIS and CIS development were relatively negative across all 3 professional groups, with physicians being the most critical. Dialogue and collaboration between developers and end users-also the youngest ones and frontline workers-need improvement; simply increasing allotted working time is unlikely to produce more positive participation experiences.

P1188 Real-world quality of life experience of subcutaneous infliximab use in children with Inflammatory Bowel Disease (IBD) at a tertiary paediatric centre

Abstract Background Subcutaneous infliximab (SC-IFX) use offers relative pharmacokinetic stability and efficacy and safety profiles comparable to intravenous-infliximab (IV-IFX) in adult patients with IBD (1-4). Regular hospital admissions for infusions have an impact Quality of Life (QoL), impacting work and school commitments as well as increasing financial burden. Aim to assess tolerability and QoL in patients switched from IV to SC infliximab collected 12 weeks after the switch. Methods A prospectively identified cohort of 33 children with IBD commenced 120mg fortnightly SC-IFX dosing between February to July 2024 in an Australian tertiary paediatric IBD service. QoL and medication tolerability questionnaires (SIAQ and Costs For Patient’s questionnaire) included assessment of tolerability, convenience, satisfaction along with data about travel time and costs were completed at week 12. Assessment of disease activity, inflammatory biomarkers and therapeutic drug monitoring occurred 4 weekly for the first 12 weeks. Results 31(94%) patients completed the 12-week study treatment period. 21 patients (68%) responded to the QOL questionnaires. Satisfaction with SC treatment was 20 (95%) across respondents, only 1 patient reporting ‘somewhat dissatisfied’ experience. 18 (85%) described ease of administration, with 3 (14%) finding injections "not easy". Respondents described financial impacts to be greatest, followed by time-commitment for attendance, loss of school and work time for attendance for infusions. Nearly 2/3 caregivers required formal leave from employment to facilitate infusion attendance, and 1/3 of patients required full day off school. 100% described a definite or probable willingness to continue SC injections beyond the 12-week period. Conclusion We describe the largest cohort of children with IBD prescribed SC-IFX with short-term follow-up. There was high treatment persistence with the drug. QOL data demonstrates high patient satisfaction, with positive impacts on patient quality-of-life with treatment described. Our real-world experience of paediatric SC-IFX use suggests this well tolerated and preferable alternative to IV-IFX dosing in children in with IBD. Further large-cohort and long-term paediatric data is required. References 1)Schreiber S, Ben-Horin S, Leszczyszyn J et al. Randomized Controlled Trial: Subcutaneous vs Intravenous Infliximab CT-P13 Maintenance in Inflammatory Bowel Disease. Gastroenterology 2021; 160: 2340-53. 2)Buisson A, Nachury M, Bazoge M et al. Long-term effectiveness and acceptability of switching from intravenous to subcutaneous infliximab in patients with inflammatory bowel disease treated with intensified doses: The REMSWITCH-LT study. Aliment Pharmacol Ther 2024; 59: 526-34. 3)Gianolio L, Armstrong K, Swann E et al. Effectiveness of Switching to Subcutaneous Infliximab in Pediatric Inflammatory Bowel Disease Patients on Intravenous Maintenance Therapy. J Pediatr Gastroenterol Nutr 2023; 77: 235-9. 4)Gianolio L, Armstrong K, Swann E et al. OC5 Effectiveness and safety of switching to subcutaneous infliximab in paediatric inflammatory bowel disease patients on established intravenous biosimilar infliximab maintenance therapy: real world data from a regional cohort. Frontline Gastroenterology 2024; 15: A4-A.