We study the breakdown of CPT symmetry which can occur in the decay process $B\overline{B}\ensuremath{\rightarrow}{l}^{\ifmmode\pm\else\textpm\fi{}}{X}^{\ensuremath{\mp}}f$ with f being a CP eigenstate. In this process, the standard model expectations for time-ordered semileptonic and hadronic events, i.e., which of the two decays takes place first, can be altered in the case that there is a violation of CPT symmetry. To illustrate this possibility, we identify and study several time-integrated observables. We find that an experiment with ${10}^{9}B\overline{B}$ pairs has the capability of improving the bound on the CPT violating parameter or perhaps observe CPT violation.