Event Abstract Back to Event Is Schizophrenia a Syndrome of Accelerated Aging? Evidence from Prospective Memory Performance Raymond C. Chan1, 2*, Xiaohong Hong3, Zhangjiang Li4, David Shum5, Ya Wang1, 2 and Xin Yu6 1 Chinese Acadamy of Science, Neuropsychology and Applied Cognitive Neuroscience Lab, Institute of Psychology, China 2 Chinese Acadamy of Science, Key Laboratory of Mental Health, Institute of Psychology, China 3 Shantou University, Mental Health Center, China 4 Capital Medical University, Beijing Anding Hospital, China 5 Griffith University, School of Psychology and Griffith Institute for Health and Medical Research, Australia 6 Peking University, Institute of Mental Health, China This study compared prospective memory (PM) performance in schizophrenic patients and healthy younger and older individuals, and to test the accelerated aging hypothesis of schizophrenia. Computerized tests of PM capturing event-and time-based tasks were administered to 30 healthy older people (M = 69.90 years, SD = 7.14 years), 30 schizophrenic patients (M = 27.10 years, SD = 8.28 years), and 30 healthy younger adults (M = 25.47 years, SD = 8.85 years). The findings showed that the healthy older individuals and schizophrenic patients demonstrated deficits in time-based PM as compared to the healthy younger adults. However, schizophrenic patients did not significantly differ from the healthy older individuals in time-based PM, even after controlling for ongoing task performances. In addition, unlike healthy older adults, schizophrenic patients were not found to be impaired in event-based PM as compared to the young adults. Subsequent analyses showed that PM did not correlate with medication level or other clinical symptoms in schizophrenia except for the relation between time-based PM and negative symptoms (r = -0.43, p = 0.018).. Taken together, these findings suggest that, in terms of level of neurocognitive functions, schizophrenia may be a developmental stage analogue to a “mild” grade of aging and support the accelerated aging hypothesis of schizophrenia. Conference: The 20th Annual Rotman Research Institute Conference, The frontal lobes, Toronto, Canada, 22 Mar - 26 Mar, 2010. Presentation Type: Poster Presentation Topic: Psychiatric Citation: Chan RC, Hong X, Li Z, Shum D, Wang Y and Yu X (2010). Is Schizophrenia a Syndrome of Accelerated Aging? Evidence from Prospective Memory Performance. Conference Abstract: The 20th Annual Rotman Research Institute Conference, The frontal lobes. doi: 10.3389/conf.fnins.2010.14.00149 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 01 Jul 2010; Published Online: 01 Jul 2010. * Correspondence: Raymond C Chan, Chinese Acadamy of Science, Neuropsychology and Applied Cognitive Neuroscience Lab, Institute of Psychology, Beijing, China, rckchan@psych.ac.cn Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Raymond C Chan Xiaohong Hong Zhangjiang Li David Shum Ya Wang Xin Yu Google Raymond C Chan Xiaohong Hong Zhangjiang Li David Shum Ya Wang Xin Yu Google Scholar Raymond C Chan Xiaohong Hong Zhangjiang Li David Shum Ya Wang Xin Yu PubMed Raymond C Chan Xiaohong Hong Zhangjiang Li David Shum Ya Wang Xin Yu Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.