Abstract Taking the cable-laying ship and the pod propeller as the research objects, based on the Reynolds time-averaged RANS equation and sliding moving grid technology, the self-propulsion numerical calculation of the coupling of the pod propeller and the hull was completed. By comparing the resistance of the bare hull and the thrust of the pod propeller, the hydrodynamic interference under the coupling state of the pod propeller and the hull is analyzed. The results show that when Fr=0.295, the total resistance of the ship increases by 21.6%, the pressure difference resistance increases by 30.5%, the wake fraction is 0.011, and the thrust derating is 0.178. The research results provide theoretical and technical guidance on the interference problem between the hull and the pod propeller.