The current study aimed to show the relationship between the levels of (activin-A hormone) and the concentration of lipids cholesterol) and the occurrence of some cases of Abortion and threatened pregnancy The study included 150 blood samples taken from aborted women and women with a threatened pregnancy, which is diagnosed by ultrasound scan and other methods such as clinical examinations and the history of the pregnant woman. Their ages ranged between (16-45) who visited Tikrit Teaching Hospital and private outpatient clinics. It was divided into three groups: The first included 50 blood samples from aborted women, 20 blood samples from women with a threatened pregnancy, and 20 blood samples from women with normal pregnancies as a control group. Blood samples were taken during the first trimester of pregnancy. The results of this study showed a significant increase in the concentration of (activin-A hormone) at a significant level (P ≤ 0.05) in the aborted women group .And women threatened with abortion compared with the control group, as well as a significant increase in the level of lipids (cholesterol) at a significant level (P ≤ 0.05)in the abortion group and the group of women threatened with abortion compared with the control group.