Thoracic Index Research Articles

Evaluation of Thorax Diameter Changes through Trunk Morphology and Different Running Intensities

During breathing, the human thorax is expanded or contracted during inspiration and expiration. The morphology of the thorax seems to be determinant for endurance efforts. This study aims to analyse the variation of the thorax cross-sections during running exercises at different intensities and the influence of thorax morphology. Twenty-two athletes were captured using a motion capture system (13 reflective markers) while they performed an incremental running test. Three captures of each subject were performed at different intensities (45%, 70%, and 85% of HRR (heart rate reserve)) and three morphology groups were made by splitting their thoracic index. The results showed a significant increase in the anteroposterior and mediolateral cross-sections when the intensity of the exercise is also increased. No differences were found in the cross-sections due to the morphology of the thorax. However, subjects with a deeper thorax showed a different behaviour as they increased their anteroposterior cross-section during higher intensities, while flatter thorax subjects did not perform in the same way. This could be explained as compensation for the morphological disadvantage that a deeper ribcage shape suffers when developing endurance efforts. More investigations regarding thorax kinematics are needed for a better understanding of breathing disorders and physical activities.

Early Cannon Development in Females of the "Sanmartinero" Creole Bovine Breed.

The variation in the dimensions of the body of living beings in relation to their size, function, or shape is known as allometry. Allometry studies allow the analysis of the function of body structures and their relationship with the performance and survival of breeds and species. The aim of this study was to describe the ontogenetic characteristics of the weight of certain bone elements of the Sanmartinero creole bovine breed, from an early age (6 months) until maturity. A total of 79 females of the Sanmartinero creole bovine breed with an age range of 0.5 to 10 years were studied. Body measurements were obtained individually using standard procedures: cannon perimeter, thoracic perimeter, body length, withers height, and body weight. Functional and production indices were obtained for animals aged more than 3 years (n = 53): corporal index, anamorphosis index, dactylo thoracic index, and the relative thickness of the cannon. The correlation between body weight and the cannon perimeter showed no trend towards a plateau. In the Sanmartinero creole bovine, therefore, a very early development of the cannon perimeter is detected, which could lead to bone fragility in heavier animals. Therefore, data suggest little harmony with appendicular bone development, i.e., with less robust cannons which are those necessary to support body mass. It is suggested that in genetic improvement programs of the Sanmartinero creole bovine, the measurement of the cannon perimeter, the withers height, and the thoracic perimeter should be considered.

THORAX AND IDIOPATHIC SCOLIOSIS

This review is related to the role of thorax in scoliogenesis. The embryology, the prenatal and the postnatal growth of the rib cage of (RC) and the lungs are briefly described. The development of normal RC, the frontal and sagittal diameters of it, the values of mid-thoracic diameters, the thoracic index, the biomechanical contribution of the RC to thoracic stability, the increase in frontal and sagittal thoracic diameter during breathing are defined. The infancy, childhood, puberty (ICP) model of growth is used in both the segmental thoracic ratios (TR) and the Segmental Rib-vertebra angles (RVA) in order to assess the normal and deformed RC in Early Onset (EOS) and Late Onset Scoliosis (LOS). The neuromuscular mechanisms as possible factors causing age-related RVAs changes are discussed. Then the posterior truncal/thoracic asymmetries are reviewed related to school scoliosis screening (SSS) referrals. Next, the development of RC is analyzed in resolving and progressive infantile idiopathic scoliosis (IIS), and in adolescent idiopathic scoliosis (AIS). The menarche and laterality of thoracic scoliotic curves, congenitally fused ribs and pulmonary function in children with idiopathic scoliosis (IS) is also discussed. The pathogenesis of IS according to the Nottingham concept and RC, the thorax and pelvis complex during gait and rotational inertia, the Double Rib Contour Sign (DRCS) and Rib Index (RI), the effect of growth on the relationship of spinal and thoracic deformity are explained. The postoperative fate of IS hump deformity in relation to the RI and the aetiological implications for IS are then stated. The role of the rib-sternum complex is mentioned. John Sevastiks thoracospinal concept of aetiopathogenesis of AIS and his research about IS are described, namely experiments on ribs, correction of experimentally produced scoliosis, suggested surgical intervention on the ribs, experiments on nerves, vascular changes in the chest wall after unilateral resection of the intercostal nerves, and breast asymmetries in female suffering AIS. A biomechanical model using different Cobb angle and rib hump (RH) correction is mentioned. The issue of thoracic kyphosis and hypokyphosis and the impact of the lateral spinal profile (LSP), that is the sagittal plane, is discussed. Finally, IS and evolution of thoracic shape as a scar of evolution are pointed out.

Description of a new clinical syndrome: thoracic constriction without evidence of the typical funnel-shaped depression—the "invisible" pectus excavatum

Pectus excavatum (PE) is a congenital malformation with a funnel-shaped depression of the sternum that can lead to cardiac symptoms. However, there are patients with thoracic constriction (defined as elevated Haller-Index > 3.25 determined by cardiac magnetic resonance imaging (CMR)) without visible evidence of PE, leading to similar complaints. Between January 2004 till June 2020, patients who underwent CMR for further evaluation of the heart, due to cardiac symptoms were enrolled and compared to controls. Biventricular global strain analysis was assessed using feature tracking (CMR-FT). ECG and/or Holter recordings were performed to detect rhythm events. Cardiac symptoms were evaluated in detail using a questionnaire. Finally, 88 patients (male 35, female 53) with elevated Haller-Index (3.9 ± 0.8) were included and compared to CMR data from 25 individuals with confirmed PE and 25 healthy controls (HC). Mean age at time of CMR was 35 ± 16 years. The most common symptoms at presentation were palpitations (41%), followed by dyspnea (24%) and atypical chest pain (14%). Three patients (3%) had atrial fibrillation or atrial flutter. Concomitant phenomena were pericardial effusion in 39% and mitral valve prolapse (MVP) in 27% of the study cohort. While there were no differences in left ventricular function or volumes, right ventricular function (RVEF) was significantly lower in patients with internal PE compared to HC (RVEF (%) 50 ± 5 vs 59 ± 4, p < 0.01). Strain analysis revealed only discrete changes in RV strain, implying a purely mechanical problem in the absence of structural changes. RV dimensions were negatively correlated with the size of thoracic indices (r = 0.41), reflecting the extent of thoracic constriction. MVP was more prevalent in patients with greater thoracic indices (r = 0.24). The described cohort, referred to as internal PE because of the absence of external changes, showed similar CMR morphologic findings as patients with real PE (especially altered dimensions of the right heart and a lower RVEF). In addition, there was a high incidence of rhythm disturbances, such as extrasystoles or arrhythmias. In one-third of the study cohort additional abnormalities such as pericardial effusion or MVP were present, with MVP being found more frequently in patients with larger thoracic indices, suggesting a possible common pathogenesis.Trial registration: ISRCTN registry, ISRCTN15355937, retrospectively registered 03.06.2022, https://www.isrctn.com/ISRCTN15355937?q=15355937&filters=&sort=&offset=1&totalResults=1&page=1&pageSize=10.

INFLUENCE OF EARLY MATING ON THE EXTERIOR FEATURES OF MEAT WOOL SHEEP

The authors presented a study on the age influence of the first mating on the ewe’s exterior of the Katun type of the Gorno-Altai breed sheep. Two groups of first-calving ewes were formed at different ages: group 1 at 12 months and group 2 at 24 months. The authors evaluated the exterior of the ewes by taking measurements. The mothers with lambs are on year-round pasture, lambing took place in May, and the authors carried out the weaning of lambs at four months. Sheep one year old and mature early have well-developed solid bones and excellent latitudinal and volumetric measurements. They are slightly inferior to those at two years of age, but the difference is not significant. The data obtained from udder studies of the udders of the studied groups show that udders of older female ewes are better developed, but the difference is unreliable. Young ewe-sheep at 12 months of age are inferior to two-year-old sows in stretching and bunching. The best development in this group was the extended leg and thoracic indexes. The bone index was about the same in all groups. Young animals obtained from ewes at the age of two years are superior to lambs from younger mothers in live weight in all periods of growth. The live weight of young animals at weaning at four months was 8.2% more (P&gt;0.95). This trend continued at six months of age, amounting to 2.8 kg. Thus, when using the broodmares in reproduction at an early age, selecting well-developed broodmares with a live weight of 38 kg or more, and providing them with optimal feeding and housing conditions, it is possible to conduct mating in the year of their birth. The mating of yarks in the year of birth will reduce maintenance costs, increase their economic life, and shorten the interval between generations, contributing to a better rate of herd genetic improvement.

Novel index to estimate the cephalocaudal extent of the excavation in pectus excavatum: The Titanic index

Quantification of the severity of pectus excavatum deformities is currently performed using the Haller index (HI) and the Correction index (CI), amongst others. However, most indexes characterize the severity at the point of maximum excavation. We present a new index, the Titanic index (TI), aimed at the appraisal of the cephalocaudal extent of the excavation and its potential clinical use. Retrospective analysis of a cohort of patients who underwent a minimally invasive repair of pectus excavatum (MIRPE) between July 2020 and April 2022at a single center. We defined TI as the percentage of the sternum that lied behind the anterior costal line observed in the CT. Demographics, HI, CI, and TI calculated based on computed tomography images (CT) were analyzed. Also, we compared the severity indexes of two groups of patients divided by the number of implants introduced per patient (group A: two implants, and group B: more than two). Seventy-eight patients (92% male) were included, with a mean age of 17.2±4.8 years. The mean TI was 37%. Albeit weak, we identified significant correlations between the TI and the HI and, more closely, to the CI. Two implants were introduced in 37 (47%) patients, and more than two in 41 (53%) patients. Compared to patients with two implants, the group of patients who received more than two implants were older and showed worse thoracic indexes. Using receiver operating characteristic curve analysis, we identified the TI as a better predictor of the need for more than two implants than HI and CI. In this regard, a TI larger than 66.5% had a sensitivity of 93% and a specificity of 92%. We propose a novel index for the categorization of the severity of pectus excavatum. This index might be useful in planning the number of implants required for complete thoracic remodeling during MIRPE. Level III. Retrospective Comparative Study.

Morphometric characterization of New Zealand white rabbit raised at different areas

The study aimed to morphometric characterization the New Zealand White (NZW) doe at three different areas. The materials used were 295 heads of NZW doe rabbits from 29 farms located at different areas. Twelve morphometric characteristics consist of body weight, eight body measurements, and three-body indices. Data analysis was performed by Mixed model, Pearson’s correlation, Principal component, and Canonical discriminant procedures. The most of parameters showed significant differences among areas. The heaviest body weight (4.71 kg) was observed in low-land and the lightest in medium land (3.54 kg). Most of the morphometric characters showed positive correlations with each other. Results of principal component show that the body indices of NZW doe raised in three different areas were similar. Canonical discriminant analysis showed that low-land was more favorable than high-land and medium land. In conclusion, The variation in size difference for morphometric characters of female New Zealand white rabbit could be explained by body index and thoracic index. The morphometric characteristics of New Zealand white doe raised in low-land area were superior to those raised in high-land and medium land areas.

Pectus excavatum in motion: dynamic evaluation using real-time MRI

ObjectivesThe breathing phase for the determination of thoracic indices in patients with pectus excavatum is not standardized. The aim of this study was to identify the best period for reliable assessments of morphologic indices by dynamic observations of the chest wall using real-time MRI.MethodsIn this prospective study, patients with pectus excavatum underwent morphologic evaluation by real-time MRI at 3 T between January 2020 and June 2021. The Haller index (HI), correction index (CI), modified asymmetry index (AI), and modified eccentricity index (EI) were determined during free, quiet, and forced breathing respectively. Breathing-related differences in the thoracic indices were analyzed with the Wilcoxon signed-rank test. Motion of the anterior chest wall was analyzed as well.ResultsA total of 56 patients (11 females and 45 males, median age 15.4 years, interquartile range 14.3–16.9) were included. In quiet expiration, the median HI in the cohort equaled 5.7 (4.5–7.2). The median absolute differences (Δ) in the thoracic indices between peak inspiration and peak expiration were ΔHI = 1.1 (0.7–1.6, p < .001), ΔCI = 4.8% (1.3–7.5%, p < .001), ΔAI = 3.0% (1.0–5.0%, p < .001), and ΔEI = 8.0% (3.0–14.0%, p < .05). The indices varied significantly during different inspiratory phases, but not during expiration (p > .05 each). Furthermore, the dynamic evaluation revealed three distinctive movement patterns of the funnel chest.ConclusionsReal-time MRI reveals patterns of chest wall motion and indicate that thoracic indices of pectus excavatum should be assessed in the end-expiratory phase of quiet expiration.Key Points• The thoracic indices in patients with pectus excavatum depend on the breathing phase.• Quiet expiration represents the best breathing phase for determining thoracic indices.• Real-time MRI can identify different chest wall motion patterns in pectus excavatum.

Productive traits of calves depending on the method of their rearing

The rearing of young animals is an important and fundamental stage in obtaining highly productive animals. The traditional technology of calves rearing in typical heated rooms provides for significant costs for their heating, ventilation, manure removal and feeding. The purpose of the work was to study the productive traits of calves depending on the method of their rearing. Research has been carried out to study the influence of different conditions of housing calves during the preweaning period under conditions in the farm “Ershov” (Vykhodnyi village) in the Buguruslansky area in the Orenburg region. The influence of housing methods on the dynamics of live weight, morphological and biochemical parameters of blood, conformation characteristics and body type indices of replacement heifers has been established. During the entire study period the average daily gain in calves of the experimental group was higher by 66 g or 9,4 % (P &lt; 0,05), live weight by 7,0 kg or 6,9 % (P &lt; 0,05). There was no significant difference in the morphological and biochemical parameters of the blood of the experimental calves. At 3 months of age the animals of the experimental group had superiority in all the measurements taken: in height at the withers by 2,0 cm or 2,2 % (P &lt; 0,05), height in the rump bone by 0,5 cm or 0,5 %, length of the body by 2,8 cm or 3,1 %, chest width by 0,9 cm or 3,6 %, chest depth by 1,5 cm or 3,9 %, chest circumference by 2,0 cm or 1,9 %, width in hook bones by 0,4 cm or 1,8 %, hip joint width by 1,1 cm or 5,4 % (P &lt; 0,05), rump half–circumference by 1,0 cm or 2,2 %, pastern circumference by 0,1 cm, or 0,8 %, compared with the corresponding indicators of calves of the control group.. Similarly, the calves of the experimental group had superiority over the analogues of the control group in terms of body type indices. Thus, according to the thoracic index the calves of the experimental group outperformed their herdmates by 9,2 abs.% (P &lt; 0,01) and according to the meatness index they outperformed the herdmates of the control group by 3,5 abs.% (P &lt; 0,05).

Diffusion tensor imaging metrics in diagnosis of HTLV‐1‐associated myelopathy

In the diagnosis of HTLV-1-associated myelopathy (HAM), while magnetic resonance imaging (MRI) is essential to exclude other diseases, its power is limited regarding HAM diagnosis, as only 30% of affected patients present with spinal cord atrophy. Diffusion tensor imaging (DTI) may enable the detection of damage in the white matter microstructure. Here, we quantitatively assess spinal cord damage using DTI and evaluate conventional MRI parameters of the spinal cord in HTLV-1-infected individuals. This cross-sectional study involved 33 HTLV-1 carriers, 28 patients with definite-HAM, and 11 seronegative healthy subjects (HS). Region-of-interest (ROI)-based fractional anisotropy (FA) and mean diffusivity (MD) measurements were performed in the upper thoracic and lumbar regions of the spinal cord. Thoracic index was defined as 1/ (anteroposterior diameter × transverse diameter) measured at the fifth 5th vertebral level. Receiver operating characteristic (ROC) curve analysis was used to determine optimal cutoff FA, MD, and thoracic index values. Spinal cord atrophy was observed in 15 (53.6%) patients with definite-HAM. The area under the ROC curve in the thoracic spinal cord was 0.824 (95% CI, 0.716-0.932), 0.839 (95% CI: 0.736-0.942), and 0.838 (95% CI: 0.728-0.949) for FA, MD, and the thoracic index, respectively. Lower FA and higher MD values were observed in the definite-HAM group compared to HTLV-1 carriers and HS at the T5 vertebral level (p < 0.01). Complementary to conventional MRI, DTI analysis of the spinal cord and thoracic index determination can offer additional insight that may prove useful in the diagnosis of HAM.

Structural indices of indigenous goats reared under traditional management systems in East Gojjam Zone, Amhara Region, Ethiopia

In phenotypic characterization of animal genetic resources, structural indices are essential components to understand the breed structure and body proportions. They are the ethnological characteristics as well as functional traits of animals providing information about the type, aptitude, and production purpose of animals. This study intends to provide information on the structural indices of indigenous goats reared under the smallholder management systems in selected districts of East Gojjam Zone, Amhara region, Ethiopia. Data on body weight and nine morphometric measurements were collected from 706 goats (589 does and 117 bucks) selected using their dentition (≥ One Pair of Permanent Incisor), physiological status (lactating females and intact males), and health condition (healthy). Nineteen structural indices were calculated from morphometric measurements and analyzed using the general linear model (GLM) procedure of the statistical analysis system (SAS, 9.0). Data were analyzed for does and bucks separately. Location had a significant (p < 0.05) influence on pelvic index, transversal and longitudinal pelvic indices, dactyl thoracic index, and relative cannon thickness index of bucks. Except for height slope, pelvic index, baron and crevat, body ratio, areal index, over increase index, weight-1, and weight-2, all other structural indices calculated for does were significantly (p < 0.05) influenced by location. Strong correlations were observed between the structural indices calculated from the linear body measurements. The study revealed that goats in the study area are longilinear and light animals that have dairy biotype. However, further studies are needed to classify the goat types for their production purposes.

Factors affecting postoperative pulmonary function deterioration in adolescent idiopathic scoliosis: A prospective study using 3-dimensional image reconstruction by biplanar stereoradiography

This study aimed both to evaluate rib cage parameters in patients with adolescent idiopathic scoliosis (AIS) by three-dimensional (3D) image reconstruction using biplanar stereoradiography (EOS) (EOS Imaging, Paris, France) and identify factors associated with postoperative pulmonary function deterioration (PFD). A total of 67 patients with Lenke type 1 or 2 AIS (59 females and 8 males; mean age, 14.4 years) undergoing posterior corrective fusion with a rod rotation maneuver based on segmental pedicle screw fixation were recruited. 3D images and pulmonary function test results were analyzed preoperatively and at 2 years postoperatively. The following parameters were measured: maximum thickness, maximum width, thoracic index, rib hump, rib cage volume (RCV), spinal penetration index (SPI), endothoracic hump ratio (EHR), vertebra-sternum angle (VSA), rib-vertebra angle difference, vertebral lateral decentering (VLD), forced vital capacity (FVC), and percent predicted FVC (%FVC). PFD was defined as a postoperative %FVC decline of 5% or greater. Patients were divided into two groups, namely PFD and non-PFD. FVC increased from 2.62 L to 2.73 L, while %FVC decreased from 88.7% to 82.7%. The maximum width diminished postoperatively in the PFD group. Patients in the PFD group exhibited a significantly smaller increase in RCV and VLD as well as a significantly smaller decrease in SPI, EHR, and VSA than those in the non-PFD group. The rib cage parameters quantified on 3D images reconstructed using EOS are useful in identifying factors affecting PFD in patients with AIS.

Radiographic vertical tracheal diameter assessment at different levels along the trachea as an alternative method for the evaluation of the tracheal diameter in non-brachycephalic small breed dogs

BackgroundTracheal narrowing due to congenital tracheal hypoplasia, acquired tracheal stenosis and tracheal collapse can lead to life-threatening respiratory distress. Tracheal hypoplasia has been identified in brachycephalic dog breeds, predominantly English Bulldogs, by measuring the tracheal diameter compared to the diameter of the thoracic inlet and creating a ratio. However, reference ranges for tracheal diameter have not been established for non-brachycephalic small breed dogs. It would be advantageous to have established tracheal diameters for non-brachycephalic small breed dogs, as these are the dogs most at risk of tracheal collapse. The main objective, of this study was to radiographically evaluate vertical tracheal diameter (VTD) at three standardized locations along the trachea of non-brachycephalic small breed dogs, in an attempt to further establish a screening diagnostic protocol for canine tracheal hypoplasia. Medical records and thoracic radiographs of non-brachycephalic small breed dogs without respiratory disease were reviewed. Right lateral radiographs were reviewed. The absolute and average VTDs at three locations (location A: caudal cervical VTD; location B thoracic inlet VTD; location C: intrathoracic VTD) were standardized by manubrium length (ML), as well as by the previously utilized thoracic inlet distance (Ti-D) and proximal 3rd rib width (PR3-W) to calculate manubrium-tracheal index (M-TI), thoracic inlet-tracheal index (Ti-TI), and proximal R3-tracheal score (PR3-TS), respectively. Correlations between averaged tracheal diameter and each of the ML, Ti-D, and PR3-W, and between M-TI and each of Ti-TI and PR3-TS were calculated.ResultsEighty-one healthy dogs met the criteria for inclusion. Significant differences (P < 0.0001) were identified among the mean values of the absolute and standardized VTDs at levels A, B, and C. The smallest tracheal diameter was identified at the level of the thoracic inlet (Level B).The average VTD correlated better with ML (rs = 0.82, P < 0.0001) compared to Ti-D and PR3-W. A relatively strong correlation (rs = 0.77, P < 0.0001) was identified between the averaged manubrium tracheal index (M-TI) and thoracic inlet tracheal index (Ti-TI).ConclusionM-TI is an appropriate alternative to Ti-TI and PR3-TS to radiographically evaluate VTD in dogs. M-TI < 0.43, < 0.34, or < 0.38 at level A, B, or C, respectively, may indicate tracheal hypoplasia in non-brachycephalic small breed dogs. Screening of canine VTD could be achieved using M-TI.

The Role of Anthropologic Measurements in Pectus Carinatum Brace Treatment Evaluation

Abstract Objectives: Brace treatment in children with pectus carinatum has become the method of choice during the last decade. The authors evaluate the role of anthropometric measurements in diagnostic and treatment processes. Methods: A prospective study, analysing a compressive brace treatment for pectus carinatum, performed between January 2018 and September 2020. Demographic data, anthropometric dimensions and indexes of the chest, data connected to an orthosis usage, as well as ongoing treatment outcomes were analysed. Results: Forty-seven consecutive patients aged between 10 to 18 years with pectus carinatum were prescribed a compressive brace. Thirtynine of them (83 %) reached clinically positive results while wearing the orthosis for 6 ± 3 months. An improvement in the sagittal chest diameter was 0.5 cm – 2.8 cm (mean 1.0 cm ± 0.5 cm) and an improvement of the Thoracic Index was 0.8 % – 25.1 % (6.4 % ± 4.5 %) by using the brace on average for (6 ± 2) hours a day. Conclusion: Clinical anthropometric measurements can evaluate the dimensions of chest wall and treatment progress in patients with pectus carinatum precisely and thus replace the need for more complex examinations requiring X-rays.

Finding suitable candidates for vacuum bell therapy in pectus excavatum patients

Vacuum bell therapy has been acceptable substitute for pectus excavatum patients who want to improve their appearance but avoid surgical correction. The aim of this study was to assess the pre-treatment characteristics of patients with pectus excavatum and to establish characteristics that can potentially help identify ideal candidates for vacuum bell therapy. Expected improvements in thoracic indices were evaluated using pre-treatment chest computed tomography, which was performed before and after applying a vacuum bell device. Treatment results after 1-year of application were evaluated using changes in the Haller index before and after treatment. The patients were categorized into two groups according the post- treatment changes in Haller index calculated using chest radiographs: those with changes in Haller index less than 0.5 (Group 1) and those with greater than or equal to 0.5 (Group 2). Pre-treatment Haller index was significantly lower in Group 1 than in Group 2 (3.1 ± 0.46 vs. 4.2 ± 1.14, respectively, p < 0.001). The expected improvement in Haller index in Group 2 was significantly higher than that in Group 1 (3.3 ± 0.60 vs. 2.8 ± 0.54, respectively, p = 0.001). The cut-off value of the expected improvement in Haller index was 0.46 with a sensitivity of 75.8% and a specificity of 83.3%. Patients who demonstrated pliability with a vacuum bell were identified as suitable candidates.

ЭКСТЕРЬЕРНО-КОНСТИТУЦИОНАЛЬНЫЕ ОСОБЕННОСТИ КОРОВ - ПЕРВОТЕЛОК ЧЕРНО-ПЕСТРОГО СКОТА ПРИ РАЗНЫХ СОЧЕТАНИЯХ ПОДБОРА

The development of dairy cattle breeding largely depends on the culture of young cattle breeding. It is very difficult to obtain and preserve young animals. Correct rearing of young cattle of dairy breeds contributes to the appropriate exhibition of genetically inherent productive abilities of animals during the first stage of their growth and development. When organizing breeding and feeding, animal growth and development characteristics are taken into account, which are determined by heredity and environmental conditions, especially feeding. The article provides a comparative analysis of the dynamics of live weight, measurements and body indexes of first-calf heifers of various selection combinations. First-calf heifers of the fifth experimental group, obtained from fathers and mothers belonging to the cross lines, exceeded animals in the control group, whose parents belonged to pure lines, in live weight and gains. Under the same housing and feeding conditions, the heifers of the studied groups did not grow in the same way, and certain differences were revealed in the process of ontogenesis. The first-calf heifers of the 5th group had the greatest live weight in different age periods and exceeded the peers of the 1st, 3rd and 4th groups from 10 to 23 kg with relevant difference. The animals of the 5th experimental group had the highest average daily gains till 6 months old. For the entire growing period (18 months), the animals in the control group had the highest relative gain, which was significantly higher than the gain in the experimental groups. The following body indexes were calculated: long-legged, elongation, pelvic-thoracic, thoracic; blockiness and bone index, as well as milk production coefficient which determined the direction of productivity of animals. First-calf cows were included into dairy-meat productivity direction according to the long-legged and elongated index. According to blockiness and thoracic index, animals of all groups belong to dairy direction of productivity, and according to bone index, to meat direction.

Numerical Assessment of a Safety System to Minimize Injuries during a Cyclist Run-Over.

Background The World Health Organization has reported that 1.35 million people die on the roads every year due to road traffic accidents. This paper focuses on exploring a passive safety system that reduces lesions in the overtaking run-over scenario. Methods Head Injury Criterion (HIC) and Combined Thoracic Index (CTI) were evaluated through numerical simulations using LS-Dyna®; in order to compare the computed results, three different speed scenarios were carried out (velocity of running over 40, 50, 60 km/h). Results The computed results were divided into groups, A for the run-over test without a passive security system and B for the run-over test with a passive security system. For case A.1, the HIC15 was 3325. For case A.2, the HIC15 was 1510, and for case A.3, the HIC 15 was 1208. For case B.1, the HIC15 2605, for case B.2, the HIC15 was 1282, and for case B.3, the HIC was 730. Conclusion The comparative results show that the passive safety system installed on the bicycle has an increased benefit impact on the severity of the injury on vulnerable road users, decreasing the probability of cranioencephalic lesions in all study cases. In addition, the thorax injuries are cut down only in the impact scenario at a speed of 40 km/h.

An Automated Approach to Differentiate Drug Resistant Tuberculosis in Chest X-ray Images Using Projection Profiling and Mediastinal Features.

In this study, an attempt has been made to differentiate Drug Resistant Tuberculosis (DR-TB) in chest X-rays using projection profiling and mediastinal features. DR-TB is a condition which is non-responsive to at least one of anti-TB drugs. Mediastinum variations can be considered as significant image biomarkers for detection of DR-TB. Images are obtained from a public database and are contrast enhanced using coherence filtering. Projection profiling is used to obtain the feature lines from which the mediastinal and thoracic indices are computed. Classification of Drug Sensitive (DS-TB) and DR-TB is performed using three classifiers. Results show that the mediastinal features are found to be statistically significant. Support vector machine with quadratic kernel is able to provide better classification performance values of greater than 93%. Hence, the automated analysis of mediastinum could be clinically significant in differentiation of DR-TB.

Three-dimensional reconstruction image by biplanar stereoradiography reflects pulmonary functional states in adolescent idiopathic scoliosis

This study investigated whether the rib cage parameters estimated based on reconstructed three-dimensional (3D) images with biplanar stereoradiography reflect pulmonary functional states in adolescent idiopathic scoliosis (AIS) patients. A total of 67 Lenke type 1 or 2 AIS patients (59 females and 8 males, mean age 14.4 years) were enrolled. All patients underwent preoperative pulmonary functional tests (PFT) and biplanar stereoradiography. Vital capacity (VC) and forced vital capacity (FVC) pulmonary functional data were collected. Rib-cage parameters (maximum thickness, maximum width, thoracic index (TI), rib hump (RH), rib-cage volume (RCV), spinal penetration index (SPI), endothoracic hump ratio (EHR), vertebra–sternum angle (VSA), rib vertebral angle difference (RVAD), and vertebral lateral decentering (VLD)) were quantified from 3D images. Patients were divided into two groups: restrictive lung disorder (RLD) (%FVC < 80%) and non-RLD (%FVC ≥ 80%). The maximum width and RCV were significantly correlated with VC (p < 0.0001), and FVC (p < 0.0001). RH, EHR, and VSA were negatively correlated with %FVC (p < 0.01). TI, SPI, and RVAD were not correlated with any pulmonary parameters. The maximum widths of RLD patients were significantly shorter than those of the non-RLD patients (218.3 mm vs. 229.7 mm, p < 0.01). The RCV of RLD patients was significantly smaller than that of the non-RLD patients (3.94 L vs. 4.49 L, p < 0.0001). The maximum width and RCV measured by 3D images with biplanar stereoradiography reflected pulmonary functional variables in patients with AIS.

Age and gender characteristics of thoracic aorta elasticity indices in patients with coronary atherosclerosis

Background. Ischemic heart disease (CHD) holds a leading position in the structure of causes of general mortality and in the structure of mortality from cardiovascular diseases. We extended the standard echocardiography with assessment of thoracic aorta elasticity to identify markers of the thoracic aorta elasticity worsen associated with coronary atherosclerosis. When analyzing the data, we identified different clinical characteristics of study participants as one of the main reasons for the difficulty in comparing the data with the results of previous studies, which made it necessary to highlight age and gender characteristics of indicators.Aim. To analyze age and gender characteristics of thoracic aorta elasticity indices in patients with coronary atherosclerosis.Material and methods. An observational analytical cross- sectional clinical trial was conducted from 2016 to 2019. Our study included 109 patients aged 39 to 82 years (mean age 65 ± 9 years, median 66 years), who were divided into 2 groups according to the results of invasive coronarography: 64 patients with coronary atherosclerosis and 45 patients without angiographic signs of coronary atherosclerosis. In the group with coronary atherosclerosis average age was 66 ± 8 years (median 66 years). In the group without coronary atherosclerosis average age was 64 ± 9 years (median 66 years). During transthoracic echocardiography, the following were obtained: coefficient of distensibility, compliance coefficient, elasticity (stiffness) module of Peterson, stiffness index of the ascending thoracic aorta; systolic velocity S, early diastolic velocity E, late diastolic velocity A of the near wall of the ascending aorta, flow velocity propagation (FVP) of the descending thoracic. Analysis of age and gender characteristics of thoracic aorta elasticity indices in patients with coronary atherosclerosis was done.Results. An increase in the stiffness index of the ascending thoracic aorta associated with coronary atherosclerosis occurs in the age group 39–66 years, a decrease in the coefficients of extensibility and compliance, an increase in Peterson’s modulus of elasticity (stiffness) of the as cending thoracic aorta — in the age group 67–82 years. A decrease in the E velocity of the near wall of the ascending thoracic aorta and FVP, associated with coronary atherosclerosis, occurs regardless of belonging to the age group, a decrease in the S velocity — in the age group 39–66 years. A decrease in the compliance coefficient of the ascending thoracic aorta, velocity S of the near wall of the ascending thoracic aorta, associated with coronary atherosclerosis, occurs only in men, an increase in the stiffness index — only in women. A decrease in the extensibility coefficient, an increase in the Peterson’s modulus of elasticity (stiffness), a decrease in the E velocity, and a decrease in CRP associated with coronary atherosclerosis occur regardless of gender.Conclusion. Worsening of the thoracic aorta elasticity in patients with coronary atherosclerosis, assessed using echocardiographic technologies, depends on gender and age.