Thin-walled Vessels Research Articles

Histological features of the vomeronasal organ in the giraffe, Giraffa camelopardalis

The vomeronasal organ (VNO) that preferentially detects species-specific substances is diverse among animal species, and its morphological properties seem to reflect the ecological features of animals. This histological study of two female reticulated giraffes (Giraffa camelopardalis reticulata) found that the VNO is developed in giraffes. The lateral and medial regions of the vomeronasal lumen were covered with sensory and nonsensory epithelia, respectively. The vomeronasal glands were positive for periodic acid-Schiff and alcian blue (pH 2.5) stains. The VNO comprises several large veins like others in the order Cetartiodactyla, suggesting that these veins function in a pumping mechanism in this order. In addition, numerous thin-walled vessels located immediately beneath the epithelia covering the lumen entirely surrounded the vomeronasal lumen. This sponge-like structure might function as a specific secondary pump in giraffes.

Bone Niches, Hematopoietic Stem Cells, and Vessel Formation.

Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in both the endosteum, in the so-called endosteal niche, and close to thin-walled and fenestrated sinusoidal vessel in the center of BM, in the so-called vascular niche. HSCs give rise to all types of mature blood cells through a process finely controlled by numerous signals emerging from the bone marrow niches where HSCs reside. This review will focus on the description of the role of BM niches in the control of the fate of HSCs and will also highlight the role of the BM niches in the regulation of vasculogenesis and angiogenesis. Moreover, alterations of the signals in niche microenvironment are involved in many aspects of tumor progression and vascularization and further knowledge could provide the basis for the development of new therapeutic strategies.

An unusual localisation of a superficial angiomyxoma.

A 40-year-old woman, without medical or surgical history, presented in our department for a gradually enlarged mass exteriorized from vagina (figure A). There was no history of vaginal discharge, lower abdominal pain or urinary complaints. On speculum examination, a pedunculated, non-tender, brownish and elastic tumor measuring 8 x 2 cm arising from the anterior cervix labium was noted (figure B), suggestive of a fibroepithelial polyp or a soft tissue tumors. The cervix was macroscopically normal. Under spinal anesthesia, a circular incision was made around the cervix implantation of the lesion with clear margins (about 1cm of the normal tissue) forcing excision of the mass. Histopathological examination revealed a lobulated tumor containing prominent myxoid stroma and thin walled vessels, with spindle to stellate tumor cells in higher power view; there were no atypical or mitotic figures in the tumor cells. The pathologic report was benign superficial angiomyxoma. The postoperative course was smooth and she was discharged 1 day after surgery. No recurrence was noted during a postoperative follow-up period of 2 years. Superficial Angiomyxoma is a benign mesenchymal tumor which rarely occurs in cervix, but it should be considered in differential diagnosis of cervical lesions, especially in women of reproductive age.

Ultrastructure of the placenta in gestational diabetes mellitus

Objectives: The placenta plays critical roles during pregnancy and is essential for fetal growth and development. Its functions are determined by the ultrastructure of the placental barrier that is an important feature to maintain the exchange surface area between the fetus and the mother. Gestational diabetes mellitus (GDM) comprises unfit conditions for embryonic and feto-placental development, and may result in placental abnormalities. The aim of this study was to detect the ultrastructural changes of the placenta in women with GDM. Methods: The placentas of 10 women with GDM without pregestational diabetics, hypertension and chronic diseases and 10 controls were studied. Six control women were delivered vaginally and the remaining cases by caesarian section at a gestational age of 36 to 39 weeks. Placental samples were measured for their thickness and prepared for light and transmission electron microscopy study. Results: Light microscopic study of the control placentas showed numerous densely packed microvilli with syncytial knots and thin-walled blood vessels and wide intervillous spaces. The placentas of GDM cases showed reduced number of microvilli with syncytial knots, thick-walled vessels, edematous spaces, areas of fibrosis and perivillous fibrinoid degeneration. Electron microscopic study of the placentas of the control women showed terminal villi with a thick layer of syncytiotrophoblasts (Sy) with a lot of regular cylindrical microvilli and a thin layer of cytotrophoblasts (Cy). There were some endoplasmic reticulum cisternae besides few mitochondria. The underlying villus core was harboring fetal capillaries lined with flat endothelial cells and thin basement membrane. There was no fibrosis or edema. In the placenta of GDM women, there was hypertrophy of Cy with atrophy of Sy with multiple vacuoles and areas for glycogen storage. The subtrophoblastic membrane was thick and the microvilli were scarce. The villous core showed congested capillaries, stromal macrophages, edematous spaces, glycogen storage areas and fibrosis. Conclusion: All the changes in placentas of gestational diabetes were attributed to associated hypoxia and oxidative stress due to decreased uteroplacental flow that was aggravated by the thick placental barrier and the presence of edema, fibrosis and glycogen storage areas that increased the distance of transfer between the fetus and mother.

Ontology-based executable design decision template representation and reuse

AbstractIn decision-based design, the principal role of a designer is to make decisions. Decision support is crucial to augment this role. In this paper, we present an ontology that provides decision support from both the “construct” and the “information” perspectives that address the gap that existing research focus on these two perspectives separately and cannot provide effective decision support. The decision support construct in the ontology is the compromise decision support problem (cDSP) that is used to make multiobjective design decisions. The information for decision making is archived as cDSP templates and represented using frame-based ontology for facilitating reuse, consistency maintaining, and rapid execution. In order to facilitate designers’ effective reuse of the populated cDSP templates ontology instances, we identified three types of modification that can be made when design consideration evolves. In our earlier work, part of the utilization (consistency checking) of the ontology has been demonstrated through a thin-walled pressure vessel redesign example. In this paper, we comprehensively present the ontology utilization including consistency checking, trade-off analysis, and design space visualization based on the pressure vessel example.

Endoscopic Ultrasound-Guided Fine Needle Aspiration Diagnosis of Intrapancreatic Accessory Spleen

Introduction: Accessory spleen (AS) is a rare congenital anomaly in which there is failure of fusion between a portion of the developing splenic tissue and the main body of the spleen. The majority of cases occur at the splenic hilum, while the second most common site is the tail of the pancreas. Intrapancreatic accessory neoplasm (IPAS) cytopathology findings include heterogeneous small lymphocytes along with traversing small vessels. Immunohistochemical staining for CD8 is a useful tool that specifically highlights the endothelial cells of the splenic sinus. Here report an additional case of IPAS diagnosed by endoscopic ultrasound (EUS) guided fine needle aspiration (FNA). Case presentation: A 20 year old Caucasian female presented as a referral to the gastroenterology department for an EUS evaluation after she had an elevated liver function test postpartum. An magnetic resonance cholangiopancreatography (MRCP) revealed an obstruction in the common bile duct and a small solid mass at the tail of the pancreas measuring 11 mm in size. She underwent an Endoscopic Retrograde Cholangiopancreatography (ERCP) with common bile duct stone removal. Endoscopic ultrasound (EUS) with FNA was performed and revealed a single hypoechoic oval welldemarcated 11.4 mm x 8.9 mm pancreatic solid mass at the tail of the pancreas. Cytopathology revealed a benign intrapancreatic accessory spleen. Cell block sections displayed branching thin walled blood vessels surrounded by lymphoid cells that shows positive immunoreactivity for CD8. Immunohistochemical stains were positive leukocyte lymphoid antigen. Conclusion: IPAS is a benign congenital anomaly that may mimic a pancreatic neoplasm. FNA can be performed for diagnosis. The use of a combination of common cytomorphologic features, immunohistochemical stains and radiologic findings will enable an accurate diagnosis and prevent unnecessary surgical procedures.

A rare case of primary hepatic solitary fibrous tumor associated with pregnancy

Purpose: To describe a case of histologically and immunohistochemically confirmed primary hepatic solitary fibrous tumor (SFT) associated with pregnancy. Case Report: A 40-year-old Caucasian woman G3P1021 with history of oral contraceptive use and no other known significant past medical history delivered via C-section in November of 2012. Two months post delivery, she noted that her abdomen did not decrease in size and sought medical attention. As part of the work-up, an abdominal MRI revealed a 15.9 cm mass centered in segment 4b of the liver with extension into segments 5 and 8 within the right lobe. In addition, an exophytic component extending inferiorly from the liver into the right mid abdomen was noted. The patient underwent an uncomplicated hepatic segmentectomy with cholecystectomy. Grossly, the tumor consisted of a firm tan-white well-circumscribed and partially encapsulated mass. Histologically, the tumor was composed of cytologically bland spindle cells with a patternless architecture with hypocellular and hypercellular areas embedded within a collagenous fibrous stroma with occasional dilated branching thin-walled blood vessels. The tumor showed no infiltrative margins or necrosis and a mitotic count of 1/10HPF. Tumor cells were strongly and diffusely positive for CD34, BCL-2, and vimentin; weakly positive for STAT6 (nuclear distribution); and focally positive for CD99 and β-Catenin. In addition, estrogen and progesterone receptors (ER and PR) were also performed and showed positive staining. The diagnosis of SFT was confirmed. To date, 36 months post-resection, our patient has been followed with imaging, showing no evidence of residual or recurrent disease. Conclusions: Primary hepatic SFT is exceedingly rare and even more so in association with pregnancy. Positive immunohistochemical staining of tumor cells for progesterone and estrogen receptors may indicate hormonal stimulation as a driver of neoplastic cell proliferation.

Glomangiopericytoma: The Sinonasal Mimic Of Soft Tissue Hemangiopericytoma

A 42-year old Filipino male with a 10-month history of progressive left nasal obstruction and rhinorrhea and a clinical impression of nasal polyposis underwent endoscopic sinus surgery with partial ethmoidectomy and polypectomy.
 We received several dark-brown, irregular, rubbery tissue fragments with an aggregate diameter of 3 cm. Histopathologic examination shows sheets of spindly tumor cells beneath the respiratory epithelial lining. These spindle cells are closely packed and arranged in short fascicles and storiform clusters surrounding hyalinized large vessels or thin-walled submucosal blood vessels. (Figures 1 and 2) There is no atypia or necrosis. Immunohistochemical studies show strong immunoreactivity to muscle specific actin, and focal reactivity to S-100. (Figure 3) Stains for CD34, caldesmon, cytokeratin, and desmin, are negative. (Figure 4) Based on these features, we diagnosed the case as glomangiopericytoma.
 Glomangiopericytoma is a rare tumor arising from the pericytes surrounding capillaries, and accounts for less than 0.5% of all sinonasal tumors.1 It has a very slight female preponderance, with a peak incidence during the seventh decade of life. The most common symptom is nasal obstruction, or epistaxis, with accompanying difficulty breathing, sinusitis and headache. A mass, or polyp is the most common clinical finding.2
 Hematoxylin–eosin staining shows a well-delineated but unencapsulated cellular tumor underneath the normal respiratory epithelium that effaces or surrounds adjacent normal structures.2 The tumor is composed of closely packed, uniform, oval to spindle-shaped cells, in short fascicles and in storiform, whorled or palisaded patterns. The cells surround numerous branching thin-walled, blood vessels, thus the morphologic resemblance to soft tissue hemangiopericytoma/solitary fibrous tumor. However, in contrast to hemangiopericytoma, glomangiopericytoma shows diffuse reactivity to muscle actins, and non-reactivity to CD34, while hemangiopericytoma shows the reverse reactions. Desmin and caldesmon are likewise non-reactive, distinguishing the tumor from leiomyomas or leiomyosarcomas of the upper aerodigestive tract. Cytokeratin non-reactivity distinguishes it from spindle cell carcinoma. S100, although typically negative, can be focally and weakly positive in a small percentage of tumor.3 
 Glomangiopericytoma is categorized as a borderline low malignancy tumor with an overall survival of >90% in 5 years but which tends to recur in up to 30% of cases. Strict follow-up is thus required, especially if complete resection is not achieved.1

Role of response to changes in flow rate in the regulation of vessel radius and blood flow

Estimates are presented for the effect of susceptibility of the inner surface of the blood vessel wall to shear stress on changes in diameter and volume blood flow rate. The model of thin-walled vessel with radius controlled by two parameters is used. The effect of rheological factors, hematocrit, and oxygen content in blood on the value of vessel response to a change in shear stress is considered. The estimates showed that the contribution of the vessel response in question to a change in blood volume flow rate amounts tens per cent. The influence of rheological (Fahraeus and Fahraeus-Lindqvist) effects on flow rate lies within several per cent. The role of the vessel response considered increases with anaemia: at low hematocrit its contribution to increase in flow rate exceeds 10%. Variation of oxygen concentration within the normal range has almost no effect on the hemodynamic parameters. With hypoxia, on the contrary, the participation of this response on changes in flow rate weakens: in severe hypoxia decrease in blood flow rate owing to a change in oxygen concentration equals approximately 9%.

Vertebral haemangioma compared to bony metastasis on magnetic resonance imaging

Vertebral haemangiomas (VHs) are benign vascular lesions of vertebral bodies, and are common incidental findings in imaging, occurring in approximately 10–12% of the adult population.1 These lesions consist of thin-walled blood vessels that pervade the medul-lary cavity between trabecula.2 Typically, VHs are asymptomatic and do not require intervention unless causing neurological compromise.

The Influence of Alloying Elements with Shape Memory Effect on Corrosion-Mechanical Properties of Welded Joints

The article contains analysis results of destruction of chemical generator corps representing thin-walled pressure vessels working under cyclic loading and in corrosive environments. It is shown that the corps made of steel 321 was destroyed mainly along the weld and heat affected zone. To improve the durability of corps we used materials with shape memory effect (SME) based on NiTi as alloying compound of welds. This allowed us to combine the functional properties of alloys with shape memory effect with increased mechanical, technological and operational properties. Accomplished electrochemical studies of corrosion behavior of steel 321 samples alloyed with NiTi in 3.5% NaCl solution, showed that the corrosion rate of welded joint and the base material are comparable. Fatigue tests in the environment KOH + H2 showed a significant reduction of ductility, which indicates the presence of hydrogen embrittlement. With increasing degree of hydrogenation the fatigue life of alloyed compounds drastically reduces.

Intravascular histiocytosis (IVH): A case report

Intravascular histiocytosis is a rare reactive cutaneous lesion of unknown pathogenesis. It is characterised by dilated vessels in the dermis containing aggregates of mononuclear histiocytes within the lumina. Most cases are reported in association with rheumatoid arthritis and cutaneous eruption typically occurs near swollen joints. The skin changes have included erythematous and violaceous macules, papules, plaques and indurated patches. We report a case of 80 years old female presented with a large erythematous patch around the right anterior shoulder joint where surgery was performed about 2 months previously. The erythematous patch was clinically thought to be erysipelas or cellulites and treated with antibiotics without response. We received a punch biopsy of skin measuring 4×6 mm. Microscopic examination of routine H&E stains revealed ectatic thin walled vessels in the dermis, the lumina of which are filled with histiocytes (macrophages). The vessels are lined by flattened single layer of endothelial cells. CD 68 and CD 31 immunostains demonstrate the macrophages within thin walled vessels. Morphological features and immunostains are consistent with intravascular histiocytosis. Diagnosis of IVH is important and may necessitate further clinical evaluation to exclude the possibility of co-existent systemic disease.

Role of Delta-Notch signaling in cerebral cavernous malformations.

Cerebral cavernous malformations (CCM) commonly known as cavernous hemangioma are associated with abnormally enlarged thin-walled blood vessels. As a result, these dilated capillaries are prone to leakage and result in hemorrhages. Clinically, such hemorrhages lead to severe headaches, focal neurological deficits, and epileptic seizures. CCM is caused by loss of function mutations in one of the three well-known CCM genes: Krev interaction trapped 1 (KRIT1), OSM, and programmed cell death 10 (PDCD10). Loss of CCM genes have been shown to be synergistically related to decreased Notch signaling and excessive angiogenesis. Despite recent evidences indicating that Notch signaling plays a pivotal role in regulating angiogenesis, the role of Notch in CCM development and progression is still not clear. Here, we provide an update literature review on the current knowledge of the structure of Notch receptor and its ligands, its relevance to angiogenesis and more precisely to CCM pathogenesis. In addition to reviewing the current literatures, this review will also focus on the cross talk between Delta-Notch and vascular endothelial growth factor (VEGF) signaling in angiogenesis and in CCM pathogenesis. Understanding the role of Notch signaling in CCM development and progression might help provide a better insight for novel anti-angiogenic therapies.

Loss of Vascular Distensibility During Exercise Is an Early Hemodynamic Marker of Pulmonary Vascular Disease

Exercise can distend the normally compliant, thin-walled pulmonary vessels. Loss of distensibility has been suggested as an early marker of pulmonary vascular remodeling. We hypothesized that in mild pulmonary vascular disease (PVD), a reduction in vascular distensibility during exercise occurs prior to the development of overt resting pulmonary hypertension (PH). Distensibility α during exercise (percentage change in vessel diameter per mm Hg increase in transmural pressure) was estimated in 90 subjects using a model of the pulmonary circulation and invasive hemodynamic data. Distensible properties in mild PVD without resting PH (PVD-noPH) (n = 33) were compared with control subjects (n = 26) and PVD with overt resting PH (PVD-PH) (n = 31). Resting mean pulmonary artery pressure (mPpa) levels were 14 ± 4, 20 ± 3, and 34 ± 10 mm Hg with corresponding exercise mPpa-cardiac output slopes of 1.5 ± 0.6, 3.5 ± 0.9, and 5.7 ± 3.2 mm Hg/L/min for control subjects and the PVD-noPH and PVD-PH groups, respectively. The distensible model produced high accuracy and precision with no mean bias and 95% limits of agreement of -4.5 to 4.5 mm Hg between calculated and measured mPpa. Distensibility α was lowest in the PVD-PH group, intermediate in the PVD-noPH group, and highest in control subjects (0.25 ± 0.14%/mm Hg vs 0.45 ± 0.24%/mm Hg vs 1.40 ± 0.45%/mm Hg, P < .0001). Distensibility α discriminated PVD-noPH from control subjects with a sensitivity of 88% and a specificity of 100%. The discriminatory performance of α was similar for the subgroup of PVD-noPH, with a strictly normal resting mPpa ≤ 20 mm Hg. Loss of pulmonary vascular distensibility during exercise occurs prior to resting PH in PVD. The usefulness of α as a novel vascular index for the early detection of PVD warrants further validation.

Primary Synovial Sarcoma of the Prostate Gland: A Review of the Literature

Background : Primary synovial sarcoma of the prostate gland (PSSP) is rare and most clinicians would be unfamiliar with its biological behaviour. Aim: To review the literature on PSSP. Methods: Various internet data bases were searched. Literature Review: PSSP is extremely rare with less than 10 cases reported; affects both young and older men; its diagnosis may be made incidentally following histological and cytogenetics examinations of prostate biopsy or prostatectomy specimens which show: A specific chromosomal translocation t(X; 18; p11; q11); Uniform spindle and oval cells which have formed interlacing fascicles that mimic fibrosarcoma. The compact fascicles of tumour cells focally alternate with hypocellular myxoid tissue which mimic peripheral nerve sheath tumours. Focal pericytomatous pattern of polygonal cells arranged around dilated, thin-walled blood vessels. PSSP tumour cells on immunohistochemical staining, stain positively with: Vimentin (most of the cells), EMA (focal positivity), Bcl-2 (strong positivity), CD99 (strong positivity), Ecadherin (strong positivity), cytokeratin (focal positivity), CD 56 and TLE/TLE1. There is no consensus opinion on treatment of PSSP which is an aggressive tumour with poor outcome. However, an aggressive radical surgical treatment by

A Pediatric Case of Solitary Myofibroma

A 5-year-old male was referred to our department for evaluation of a firm elastic mass at the back of his head. Clinical examination revealed no abnormalities but the local area was tender. Further clinical and radiological examinations yielded no pathological findings and no other lesions were detected. The lesion was located in the diploic layer of the left parietal bone. The inner layer of the skull intact but the outer layer showed osteolytic change. The lesion did not adhere to the dura mater. The tumor was completely removed with the surrounding bone. Histological examination revealed a mesenchymal tumor comprised of myoid spindle-shaped cells arranged in whorls between muscle cells and fibroblasts and a vascular component around the spindle cells. The final diagnosis was myofibroma. The patient recovered well after the operation and he was discharged from hospital 10 days after surgery. Clinical and radiological follow-up 6 and 12 months later showed neither recurrence of the primary lesion nor any indications of lesions at other sites. Myofibroma is a benign neoplasm composed of myoid cells with thin-walled blood vessels. This tumor, reported to have a wide range of clinical manifestations, is one of the cranial vault tumors. These tumors occur mainly in children although a few affected infants have been reported. Surgical intervention may contribute significantly to the diagnosis of solitary myofibroma and complete removal achieves good outcomes. Herein, we report a 5-year-old male with solitary myofibroma of the skull, presenting as a firm elastic mass in the left parietal bone.

Acquired vulvar lymphangioma circumscriptum

Lymphangioma circumscriptum is a benign dilatation of lymph channels localized to the skin and subcutaneous tissues. This dermatological condition is generally found localized to the oral mucosa, tongue, proximal parts of arms and legs, groin, axilla, and trunk. Primary vulvar involvement is very rare. This report dwells on a 61-year-old female presenting with multiple itchy translucent warty papules on the left vulva. These lesions had been present for the past 3 years, and were gradually increasing in number and size. She had undergone a hysterectomy for uterine carcinoma 13 years ago, and had subsequently developed lymphedema of the left leg. Histopathologic examination of the biopsied vulvar papule demonstrated hyperkeratotic epidermis and dilatation of thin-walled lymph vessels in superficial dermal papillae. The physiopathological features helped clinch the diagnosis of vulvar lymphangioma circumscriptum.

True stress and shakedown analysis of pressure vessel under repeated internal pressure

This study aims to investigate the true stress and the plastic shakedown behavior of a cyclically loaded pressure vessel. To serve this study, an experimental platform has been built up, which comprised of a self-made thin-wall cylinder pressure vessel, a water pressure loading system to simulate the actual working loading condition, and strain gauge sets for strain measurement. A number of experiments have been done by cyclically loading and unloading the vessel at different strain levels of plastic deformation to shakedown state in different experiments respectively. The relationship between plastic strain and shakedown range has therefore been obtained. The true stress-strain constitutive model of the vessel under large deformation condition has also been derived. The experiments lead to three observations: (1) the strain hardening technology can effectively reduce the residual stress of stainless steel pressure vessel. (2) The shakedown range is less than 2000 μe for a total strain under 4%, and yet the shakedown range increases fast to more than 3000 μe for a total strain higher than 6%. (3) It is also found that the true stress-strain constitutive model given in this paper describes the multi-axial stress-strain state of pressure vessels, and validates the engineering practicability of conventional uniaxial tensile shakedown constitutive curve.

B-mode ultrasonographic measurement of inferior vena cava diameter among healthy adults in Kano, Nigeria

Background: The inferior vena cava (IVC) is thin-walled compliant vessel that adjust the body volume status by changing its diameter depending on the total body fluid volume. sonographic measurement of IVC diameter has been reported as an alternative, rapid and non-invasive method of volume assessment of body fluids. The aim of this study is to determine the normal IVC diameter among healthy adults in Kano, Nigeria. Materials and Methods: Sonographic measurement of IVC of healthy adults with age ranging between 15 and 65 years was done with the subject in the supine position. The intrahepatic portion of its diameter was measured at about 2 cm proximal to the hepatic veins in a longitudinal plane in both inspiratory and expiratory phases of respiration. Three repeated measurements were done to reduce intra-observer variability in this prospective cross-sectional study. Results: A total of 400 adults comprising 173 (43.3%) males and 227 (56.8%) females were recruited using Fisher's statistical formula for sample size determination. The mean age of the subjects was 32.4 ± standard deviation 10.9 years. The mean inspiratory diameter was 10.1 ± 2.7 mm (ranging from 4.8 mm to 18.8 mm). The overall mean IVC expiratory (IVCexp) diameter in this study was 16.7 ± 2.7 mm (range = 10.9–25.4 mm). The mean IVCexp diameter was slightly higher for males than for females (males: 17.1 ± 2.8 mm; females: 16.3 ± 2.7 mm). This difference was statistically significant ( P = 0.0022). There was a gradual decrease in IVC diameter with advancing age. Conclusion: This study was able to generate normal IVC diameter in a sample of Nigerians which may serve as a reference for normal values in Black Africans.

Pure spinal epidural cavernous hemangioma: A case series of seven cases.

Introduction:Pure spinal epidural cavernous hemangiomas (PSECHs) are rare vascular lesions with about 100 cases reported. Herein, we present a case series of 7 PSECHs discussing their clinical presentation, radiological characteristics, surgical technique and intraoperative findings, pathological features, and functional outcome.Materials and Methods:We retrieved from the retrolective databases of the senior authors, patients with pathologically confirmed PSECH operated between January 2002 and November 2015. From their medical records, the patients’ sociodemographic, clinical, radiological, surgical, and histopathological data were retrieved and analyzed.Results:The mean age of the seven cases was 50.3 years. Four were females. All the five cases (71.4%) in the thoracic spine had myelopathy and the 2 (28.6%) lumbar cases had sciatica. Local pain was present in all the cases. All the lesions were isointense on T1-weighted images, hyperintense on T2-weighted images, and in five cases there was strong homogeneous enhancement. In six cases (85.7%), classical laminectomy was done; lesions resected in one piece in five cases. Total excision was achieved in all the cases. Lesions were thin-walled dilated blood vessels, lined with endothelium, and engorged with blood and with scanty loose fibrous stroma. The median follow-up was 12 months (range: 1–144 months). All patients gradually improved neurologically and achieved a good outcome with no recurrence at the last follow-up.Conclusion:PSECH although rare is increasing reported and ought to be included in the differential diagnosis of spinal epidural lesions. Early surgical treatment with total resection is recommended as would result in a good prognosis.