When rats deficient in thiamine, riboflavin, pyridoxine or pantothenate were allowed their choice of casein, sucrose, hydrogenated fat, or salt mixture, certain specific differences between their food selections and those of control animals were observed. The thiamine-deficient group selected more fat and less protein that the controls; the pyridoxine-deficient group selected less protein; and the pantothenate group much less fat and more carbohydrate than the controls. Possible explanations of these results are considered.