Thermoplastic Denture Base Resins Research Articles

The Cytotoxic Effect of Thermoplastic Denture Base Resins: A Systematic Review.

Partial or complete dentures are constructed from thermoplastic resins that are thermally processed and molded. This review examines the presently available evidence for the cytotoxicity of thermoplasticized denture base resins on human gingival epithelial cells, adipose cells, and fibroblasts; human amnion fibroblasts; and mouse fibroblasts. Electronic searches were performed on PubMed, Scopus, Web of Science, and Google Scholar databases to identify relevant articles to be included in the review until September 2022. Clinical, in vivo, and in vitro studies in English language were searched for. The quality of the studies was assessed using the Toxicological data Reliability Assessment tool (ToxRTool) developed by the European Commission's Joint Research Centre. GRADE assessment was used to evaluate the certainty of evidence. Seven in vitro studies were included in the review. The overall risk of bias was determined to be high, with the majority of studies assessed found to be reliable with restrictions or not reliable. Only two studies were considered reliable without restrictions based on ToxRTool assessment. The effect of thermoplastic denture base resins on viability and cell adherence of human gingival or amnion fibroblasts and mouse fibroblasts (L929s) is not significant. Conditioned media from unpolished specimens of resins were significantly more toxic to cultured cells than those from polished specimens. This may be of concern in cases of poor post-processing of dentures. Based on the limited evidence available, there is low-certainty evidence that thermoplastic denture base resins appear to be biocompatible and show insignificant cytotoxicity. Further well-designed trials adhering to standard reporting guidelines and using objective measures are necessary before outlining universal guidelines for best practice. Long-term in vivo and clinical assessment is necessary to corroborate laboratory findings with clinical outcomes. Denture base resins are in constant contact with oral tissues, and cytotoxic components released by the resins may irritate or inflame the tissues or provoke an allergic response.

Effect of retention hole designs in artificial teeth on failure resistance of the connection with thermoplastic resin.

This study aimed to evaluate the effect of retention hole designs in artificial teeth on failure resistance of the connection with a thermoplastic denture base resin. Artificial teeth with the following retention hole designs were attached to polyester and polyamide resins: no hole, vertical hole, horizontal hole, and vertical and horizontal holes. An artificial tooth with no hole attached to polymethyl methacrylate was prepared as the control. The load was applied until connection failure occurred between the artificial tooth and resin, and failure resistance was detected. Although the control showed the highest resistance, the artificial tooth with vertical and horizontal holes showed higher resistance than those with other retention hole designs in both thermoplastic resins. Providing vertical and horizontal retention holes in artificial teeth may be effective in improving failure resistance of the connection with thermoplastic resins.

Oral health–related quality of life of conventional removable partial dentures, unilateral nonmetal clasp dentures, and shortened dental arch with 2- or 3-tooth unilateral distal extension tooth loss in the mandible: A randomized, crossover, clinical trial

Statement of problemConventional removable partial dentures with metal clasps are still a common option for patients with distal-extension tooth loss. However, unilateral nonmetal clasp dentures fabricated by using a thermoplastic denture base resin are increasingly being used. Furthermore, the shortened dental arch concept remains controversial, in spite of being advocated for many years. Nevertheless, these treatment options remain controversial, particularly in patients with the loss of a few distal teeth unilaterally. PurposeThe purpose of this randomized, crossover, clinical trial was to investigate the oral health–related quality of life of participants who requested a new dental prosthesis (unilateral nonmetal clasp dentures or conventional removable partial dentures) at a private practice. Material and methodsA 3-period, randomized, crossover design was used in a within-subject, controlled, clinical trial. Twenty-four participants (mean age 59.0 years [7 men: 62.6 {45–85} years; 17 women: 57.5 {24–75} years]) were enrolled. All experimental procedures were approved by the Ethics Committee of Nagasaki University Hospital (#15022313) and registered in the International Standard Randomized Controlled Trial Number registry (ISRCTN49105064). All participants were fully dentate in the maxilla and had unilateral distal-extension loss of 2 or 3 teeth in the mandible. Participants were allocated to 1 of 6 groups and treated with prescribed options in accordance with their allocated sequences and used a dental prosthesis or nothing for 2-week periods. At the end of each intervention, the participants were asked to answer the Oral Health Impact Profile questionnaire. Differences in Oral Health Impact Profile scores among groups were estimated with a mixed-effects model (α=.05). ResultsTotal Oral Health Impact Profile scores were higher for unilateral nonmetal clasp dentures (P=.002) and shortened dental arch (P=.049) than for conventional removable partial dentures, with medium and small effects. The unilateral nonmetal clasp dentures had a similar effect compared with shortened dental arch (P>.05). unilateral nonmetal clasp dentures (P=.011) and shortened dental arch (P=.005) demonstrated medium effects in the oral function dimension compared with conventional removable partial dentures. Unilateral nonmetal clasp dentures exhibited large and medium effects in the orofacial appearance dimension compared with conventional removable partial dentures (P=.001) and shortened dental arch (P=.006). In the orofacial pain dimension, shortened dental arch showed effects similar to those of conventional removable partial dentures and unilateral nonmetal clasp dentures (P>.05), and no significant differences were observed in the psychosocial impact dimension (P>.05), but the unilateral nonmetal clasp denture score was lower than the conventional removable partial denture score, with a small effect. Men had significantly lower total Oral Health Impact Profile scores for shortened dental arch than women (P=.033). ConclusionsUnilateral nonmetal clasp dentures and shortened dental arch were better than conventional removable partial dentures for the oral health–related quality of life of individuals with unilateral distal-extension tooth loss in the mandible, and sex had a significant effect on removable prosthetic planning.

Bond strength of artificial teeth to thermoplastic denture base resin for injection molding.

This research was conducted to investigate the bond strength between artificial teeth and a thermoplastic denture base resin for injection molding with different surface preparations for use in flexible resin removable partial dentures. Composite resin denture teeth and acrylic denture resin teeth were bonded to three types of thermoplastic denture base resins for injection molding (polyamide, polyester, and polycarbonate) and a conventional heat-polymerized polymethyl methacrylate (PMMA) resin (control). The ridge lap surfaces of the artificial teeth were classified into four groups based on the type of ridge lap surface treatment applied (n=10): no treatment, ethyl acetate, small T-shaped tunnel, and large T-shaped tunnel. The specimens were tested for bond strength. The results showed that the ethyl acetate treatment was ineffective for enhancing the bond strength (p>0.05) between the artificial teeth and thermoplastic denture base resin for injection molding, whereas the T-shaped tunnel was quite effective in this regard (p<0.05).

Fracture Force Evaluation, Deflection, And Toughness On Three Repaired Injection Molded Pmma Denture Base Resins

To date, the management of fractured dentures made from high-impact acrylic polymers is challenging . Hence this study is aimed to evaluate fracture force, toughness, and deflection on three types of repaired injection-molded polymethyl methacrylate thermoplastic denture base resins. In this in-vitro study, the sample size was estimated to 20 samples per group (group A, B, and C) using G*power 3.0.10 software with power 80% and alpha error of 5%. So, a total of 60 high-impact injection-molded ac

Evaluation of Some Physical and Mechanical Properties of Chitosan Modified Thermoplastic Denture Base Resin

Evaluation of Some Physical and Mechanical Properties of Chitosan Modified Thermoplastic Denture Base Resin

Evaluation of some physical and mechanical properties of chitosan modified thermoplastic denture base resin

Abstract: Objective: This study was aimed to evaluate the effect of incorporation of chitosan nanoparticles (Cs/NPs) on flexural strength, impact strength, fracture toughness as well as, water sorption and solubility of thermoplastic resin material. Materials and Methods: Cs/NPs (Nano-gate Company, Egypt) was incorporated into thermoplastic resin (Bre-flex, Bredenttm, Germany) with different concentration (1.5 wt., 5wt., and 7 wt.%). This study was divided into four main groups; unmodified “control group” and four modified groups according to the concentration of the incorporated Cs/NPs. Results: The results of this study revealed that; the incorporation of Cs/NPs decrease the flexural strength, impact strength, and fracture toughness of thermoplastic resin. While, the water sorption and solubility of modified thermoplastic resin were increased. Conclusion: The incorporation of Cs/NPs into thermoplastic resin at different concentrations could adversely affects its flexural strength, impact strength, fracture toughness as well as its water sorption and solubility. Key Wards: Chitosan, Nanoparticles, Mechanical properties, physical properties, Thermoplastic resin.

Adaptation accuracy and mechanical properties of various denture base resins: a review

This paper reviews the adaptation accuracy and mechanical properties of currently used denture processing systems with base resin materials and introduces the latest research on the development of antimicrobial denture base resins. Poly(methyl methacrylate) has been successfully used as a dental denture base resin material by the compress-molding method and heat polymerization for a long time, but recently, new processing techniques, injection molding-methods or fluid-resin technique are also used for fabricating denture base. However, studies indicated that there was no difference between the injectionmolding and the conventional compression-molding method in terms of adaption accuracy of denture base. The fluid-resin fabrication and one injection-molding systems exhibited better adaptation accuracy than the other processing methods. Resin denture bases in the oral cavity may undergo midline fractures due to flexural fatigue from repeated masticatory loading. For those patients, impact resistant denture base resins are recommended to prevent denture fracture during service. Thermoplastic denture base resins can be helpful for patients suffering from allergic reaction to resin monomers with a soft-fit, however, thermoplastic resins with low stiffness can irritate gum tissues and accelerate abnormal alveolar ridge resorption. Moreover, due to low chemical durability in oral cavity, those should be used for a limited period of time.

Effect of cellulose nanofiber content on flexural properties of a model, thermoplastic, injection-molded, polymethyl methacrylate denture base material

Cellulose nanofiber (CNF) made from wood-derived fiber is considered as a potential alternative reinforcing material to conventional fibers. The aim of this study was to investigate the effect of CNF on the flexural properties of CNF-reinforced, injection molded, polymethyl methacrylate (PMMA) denture base material. Test specimens were fabricated from a model thermoplastic denture base resin using the injection molding technique. The resin pellets were mixed with CNF (to obtain different weight percentages 5, 10, 15, and 23 wt%). PMMA without CNF served as the control (0 wt%). Prior to the testing, the test specimens (n = 12/group) were water-immersed at 37 °C water for 50 h. The flexural strengths and moduli of the specimens were determined using three-point bending tests. Statistical evaluation included a one-way analysis of variance and the Student-Newman-Keuls test (α = 0.05). The mean and standard deviation of flexural strengths with the addition of 0, 5, 10, 15 and 23% CNF were 49.4 (±0.7), 56.4 (±1.3), 63.5 (±2.0), 72.0 (±4.7), and 96.8 (±4.0) MPa, respectively. The mean and standard deviation of flexural modulus with the addition of the same concentrations of CNF were 1.31 (±0.02), 1.56 (±0.05), 1.99 (±0.14), 2.40 (±0.15), and 3.96 (±0.08) GPa, respectively. The flexural strengths and moduli of the CNF-reinforced PMMA were significantly higher than those of pure PMMA (p < 0.05). Hence, incorporation of CNF can significantly improve flexural properties of a thermoplastic PMMA denture base material.

Physical properties and color stability of injection-molded thermoplastic denture base resins.

PURPOSEThe purpose of this study was to compare mechanical and physical properties of injection-molded thermoplastic denture base resins.MATERIALS AND METHODSIn this study, six commercially available products (VA; Valplast, LC; Lucitone, ST; Smiltone, ES; Estheshot-Bright, AC; Acrytone, WE; Weldenz) were selected from four types of thermoplastic denture base materials (Polyamide, Polyester, Acrylic resin and Polypropylene). The flexural properties and shore D hardness have been investigated and water sorption and solubility, and color stability have evaluated.RESULTSFor the flexural modulus value, ES showed the highest value and WE showed significantly lower value than all other groups (P<.05). Most of experimental groups showed weak color stability beyond the clinically acceptable range.CONCLUSIONWithin the limits of this study, thermoplastic denture base resin did not show sufficient modulus to function as a denture base. In addition, all resins showed discoloration with clinical significance, and especially polyamides showed the lowest color stability.

Shear Bond Strength of Acrylic Denture Teeth to PMMA and Polyamide Denture Base Materials

Introduction: Detachment of denture teeth from denture base is one of the most common reasons for costly denture repairs .This study aimed at evaluating the bond strength of an acrylic denture tooth to polyamide injection-molded thermoplastic denture base material compared with three conventional polymethylmethacrylate (PMMA) denture base resins. Materials and Method: A total of 40 acrylic denture molar teeth were randomly allocated into four groups (n=10) of heat-polymerized (HP), Auto-polymerized (AP), Injection molded (IM) and Polyamide thermoplastic (PT). All denture base/acrylic teeth combinations underwent 5000 thermal cycles (5-55◦C).Samples were subjected to shear bond strength test by a universal testing machine with a 1 mm/min crosshead speed .Data were analyzed using ANOVA and Tukey’s tests(α=0.05). Results: Mean ±SD of shear bond strength values were (MPa) 4.82±1.21, 4.52±1.67, 3.7±0.84 and 4.13±2.21 for groups HP, AP, IM and PT respectively. No significant difference was found among the experimental groups (P=0.429). Conclusion: Polyamide thermoplastic denture base resin was similar to conventional PMMA denture base materials in terms of bond strength to artificial denture teeth.

Effects of relining materials on the flexural strength of relined thermoplastic denture base resins.

PURPOSEThe aim of this study was to evaluate the effects of relining materials on the flexural strength of relined thermoplastic denture base resins (TDBRs).MATERIALS AND METHODSFor shear bond strength testing, 120 specimens were fabricated using four TDBRs (EstheShot-Bright, Acrytone, Valplast, Weldenz) that were bonded with three autopolymerizing denture relining resins (ADRRs: Vertex Self-Curing, Tokuyama Rebase, Ufi Gel Hard) with a bond area of 6.0 mm in diameter and were assigned to each group (n=10). For flexural strength testing, 120 specimens measuring 64.0×10.0×3.3 mm (ISO-1567:1999) were fabricated using four TDBRs and three ADRRs and were assigned to each group (n=10). The thickness of the specimens measured 2.0 mm of TDBR and 1.3 mm of ADRR. Forty specimens using four TDBRs and 30 specimens using ADRRs served as the control. All specimens were tested on a universal testing machine. For statistical analysis, Analysis of variance (ANOVA) with Tukey's test as post hoc and Spearman's correlation coefficient analysis (P=.05) were performed.RESULTSAcry-Tone showed the highest shear bond strength, while Weldenz demonstrated the lowest bond strength between TDBR and ADRRs compared to other groups. EstheShot-Bright exhibited the highest flexural strength, while Weldenz showed the lowest flexural strength. Relined EstheShot-Bright demonstrated the highest flexural strength and relined Weldenz exhibited the lowest flexural strength (P<.05). Flexural strength of TDBRs (P=.001) and shear bond strength (P=.013) exhibited a positive correlation with the flexural strength of relined TDBRs.CONCLUSIONThe flexural strength of relined TDBRs was affected by the flexural strength of the original denture base resins and bond strength between denture base resins and relining materials.

Nonthermal plasma on the shear bond strength of relining resin to thermoplastic denture base resin

Nonthermal plasma on the shear bond strength of relining resin to thermoplastic denture base resin

Investigation of the cytotoxicity of thermoplastic denture base resins.

PURPOSEThe purpose of this study was to investigate the in vitro cytotoxicity of thermoplastic denture base resins and to identify the possible adverse effects of these resins on oral keratinocytes in response to hot water/food intake.MATERIALS AND METHODSSix dental thermoplastic resin materials were evaluated: three polyamide materials (Smile tone, ST; Valplast, VP; and Luciton FRS, LF), two acrylic materials (Acrytone, AT; and Acryshot, AS), and one polypropylene resin material (Unigum, UG). One heat-polymerized acrylic resin (Vertex RS, RS) was chosen for comparison. After obtaining extracts from specimens of the denture resin materials (Φ=10 mm and d=2 mm) under different extraction conditions (37℃ for 24 hours, 70℃ for 24 hours, and 121℃ for 1 hour), the extracts (50%) or serial dilutions (25%, 12.5%, and 6.25%) in distilled water were co-cultured for 24 hours with immortalized human oral keratinocytes (IHOKs) or mouse fibroblasts (L929s) for the cytotoxicity assay described in ISO 10993.RESULTSGreater than 70% viability was detected under all test conditions. Significantly lower IHOK and L929 viability was detected in the 50% extract from the VP (70℃) and AT (121℃) samples (P<.05), but only L929 showed reduced viability in the 50% and 25% extract from LF (37℃) (P<.05).CONCLUSIONExtracts obtained from six materials under different extraction conditions (37℃, 70℃, and 121℃) did not exhibit severe cytotoxicity (less than 70% viability), although their potential risk to oral mucosa at high temperatures should not be ignored.

A Comparative Assessment of the Surface Roughness of Thermoplastic Denture Base Resins Following Adjustment and Re-Polishing

Purpose: This study assessed the roughness of two injection-molded, thermoplastic materials used for denture bases compared with a polyamide material and compression molded Polymethylmethacrylate (PMMA) after the adjustment and re-polishing with either a laboratory protocol or a chair side protocol. Methods: Forty specimens, each of PMMA, Valplast, DuraFlex, Dura Cetal were fabricated and finished according to individual manufactures’ instructions. These materials were adjusted with tungsten carbide (TC) burs to mimic gross adjustments, and then re-polished either on a lathe or bonded silicon carbide (B-SC). Following instrumentation, the specimens were assessed using contact profilometry and scanning electron microscopy. Two-factor ANOVA was used to determine significant differences in mean surface roughness (Ra and Rmax), with included factors being material type and re-polishing regimen. Results: Mean Ra values ranged from 0.26 (DuraFlex control) to 1.82 (Valplast adjusted with TC burs). Mean Rmax values ranged from 1.88 (Dura Flex control) to 13.76 (Valplast adjusted with TC burs). Two-factor ANOVA revealed that interaction of both factors was significant (p < 0.05) for Ra and Rmax. There was a statistically significant increase in both Ra (p < 0.05) and Rmax (p < 0.05) for all material types following the gross adjustment. With the exception of DuraFlex, re-polishing of samples that were previously adjusted with TC burs, on the dental lathe produced surfaces that were comparable to control samples. Conclusion: Adjustment of DuraFlex should be kept to a minimum since the adjustment produced the significant surface detriment that could not be corrected with either of the polishing regimens.

Bond strength of a chairside autopolymerizing reline resin to injection-molded thermoplastic denture base resins

PurposeThis study evaluated the shear bond strength of a chairside autopolymerizing reline resin to injection-molded thermoplastic denture base resins. MethodsFour kinds of injection-molded thermoplastic resins (two polyamides, a polyethylene terephthalate copolymer and a polycarbonate) and PMMA, as a control, were tested. The eight types of surface treatment: ((1) no treatment, (2) air abrasion, (3) dichloromethane, (4) ethyl acetate, (5) 4-META/MMA-TBB resin, (6) air abrasion and 4-META/MMA-TBB resin, (7) tribochemical silica coating, and (8) tribochemical silica coating and 4-META/MMA-TBB resin) were applied to each specimen. The chairside autopolymerizing reline resins were bonded to disks of the injection-molded thermoplastic denture base resins. All of the specimens were immersed in water for 4 months and then thermocycled for 10,000 cycles in water between 5 and 55°C. The shear bond strengths were determined. ResultsThe shear bond strengths of the two polyamides treated using air abrasion, dichloromethane and ethyl acetate and no treatment were exceedingly low. The greatest bond strength was recorded for the polyethylene terephthalate copolymer specimens treated with tribochemical silica coating and 4-META/MMA-TBB resin (22.5MPa). The bond strengths of the other injection-molded thermoplastic denture base resins increased using 4-META/MMA-TBB resin. ConclusionsTribochemical silica coating and 4-META/MMA-TBB resin were the most effective surface treatments among all denture base resins tested.

Wear resistance of injection-molded thermoplastic denture base resins

Objective This study investigated the wear resistance of injection-molded thermoplastic denture base resins using nanoindentation instrument.Materials and methods Six injection-molded thermoplastic denture base resins (two polyamides, two polyesters, one polycarbonate, one polymethylmethacrylate [PMMA]) and a PMMA conventional heat-polymerized denture-based polymer control were tested. Elastic modulus, hardness, wear depth, and roughness were calculated using a nanoindentation instrument.Results Elastic modulus and hardness of the injection-molded thermoplastic denture base resins were significantly lower than those of the PMMA conventional heat-polymerized denture-based polymer. Wear depth of polycarbonate and PMMA conventional heat-polymerized denture-based polymer were significantly higher than that of other injection-molded thermoplastic denture base resins. The roughness of injection-molded thermoplastic denture base resins was significantly more than that of PMMA conventional heat-polymerized denture-based polymer after testing.Conclusions Wear resistance of injection-molded thermoplastic denture base was low compared to PMMA conventional heat-polymerized denture-based polymers.

Adhesive bonding of injection-molded thermoplastic denture base resins and prosthodontic application

Adhesive bonding of injection-molded thermoplastic denture base resins and prosthodontic application

Effect of Reinforcement on the Flexural Properties of Injection-Molded Thermoplastic Denture Base Resins.

To evaluate the effect of reinforcement on the flexural properties of injection-molded thermoplastic denture base resins. Three injection-molded thermoplastic denture base resins (polyamide, polyester, polycarbonate) were selected for this study, and a conventional heat-polymerized denture base resin (PMMA) was used as a control. Continuous unidirectional glass fiber-reinforced composite (FRC) and metal wire were used for reinforcement. Reinforced bar-shaped specimens (65 mm long, 10 mm wide, 3.3 mm high) were fabricated (n = 10). The flexural strength at the proportional limit (FS-PL) and the elastic modulus were measured using a three-point bending test. All the denture base material specimens reinforced with FRC possessed a significantly higher FS-PL compared to those without reinforcement. The FS-PL of the polycarbonate specimens reinforced with metal wire was significantly higher than that without reinforcement, and there was no significant difference in the FS-PL between the polycarbonate specimens reinforced with FRC and those with metal wire. The order of the elastic modulus according to the denture base material, arranged in terms of statistical significance, was as follows: PMMA (3.46 ± 0.53 GPa) > polycarbonate (2.69 ± 0.48 GPa) > polyester (2.00 ± 0.39 GPa) > polyamide (1.14 ± 0.35 GPa). The order of the elastic modulus according to the reinforcement, arranged in terms of statistical significance, was as follows: metal wire (2.74 ± 0.96 GPa) > FRC (2.40 ± 0.89 GPa) > no reinforcement (1.82 ± 0.83 GPa). Continuous unidirectional glass fiber-reinforced composite (FRC) reinforcement had a satisfactory reinforcing effect for the injection-molded thermoplastic denture base resins.

The effect of cycling deflection on the injection-molded thermoplastic denture base resins

Objective. The aim of this study was to evaluate the effect of cycling deflection on the flexural behavior of injection-molded thermoplastic resins. Materials and methods. Six injection-molded thermoplastic resins (two polyamides, two polyesters, one polycarbonate, one polymethyl methacrylate) and, as a control, a conventional heat-polymerized denture based polymer of polymethyl methacrylate (PMMA) were used in this study. The cyclic constant magnitude (1.0 mm) of 5000 cycles was applied using a universal testing machine to demonstrate plasticization of the polymer. Loading was carried out in water at 23ºC with eight specimens per group (n = 8). Cycling load (N) and deformation (mm) were measured. Results. Force required to deflect the specimens during the first loading cycle and final loading cycle was statistically significantly different (p < 0.05) with one polyamide based polymer (Valplast) and PMMA based polymers (Acrytone and Acron). The other polyamide based polymer (LucitoneFRS), polyester based polymers (EstheShot and EstheShotBright) and polycarbonate based polymer (ReigningN) did not show significant differences (p > 0.05). None of the materials fractured during the loading test. One polyamide based polymer (Valplast) displayed the highest deformation and PMMA based polymers (Acrytone and Acron) exhibited the second highest deformation among the denture base materials. Conclusion. It can be concluded that there were considerable differences in the flexural behavior of denture base polymers. This may contribute to the fatigue resistance of the materials.