A high-precision ohmmeter that delivers rectangular pulses to the connected thermal sensors of various designs was developed. During the heating pulse, the electrical resistance of the sensor(s) is measured at a given frequency. The thermophysical properties of the objects under study are calculated according to conventional models. The device is capable of implementing both absolute and relative measurements, which are carried out in one pulse. The uncertainty of the measured current-voltage characteristics of the measurement channel was estimated. Experiments were conducted on human skin using small-size Pt100 platinum resistance thermometers on a substrate. The use of modern sensors on a coated substrate extends the application range of the developed device in terms of non-destructive analysis of such thermophysical properties, as thermal conductivity, thermal activity, thermal diffusivity, boiling and melting temperatures of conductive and magnetically conductive measurement objects. The compact size of the sensor permits investigations on small volumes. The range of measured temperatures and pressures is determined by the sensor. The device compactness enables its use for both industrial purposes in laminar flow environments and educational purposes. The device can be used to study the thermophysical properties of plastic amorphous and bulk materials, biological and plant objects, liquids and gases and their mixtures, solids, inhomogeneous bodies in structure with and without a melting component. The irregular thermal regime allows fast and/or irreversible processes with a thermal field to be studied.