Recently, studies have focused more attention on surface feature extraction using thermal infrared remote sensing (TIRS) as supplementary materials. Innovatively, in this paper, using three-date (winter, early spring, and end of spring) TIRS Band 10 images of Landsat-8, we proposed an empirical normalized difference of a seasonal brightness temperature index (NDSTI) for enhancing a built-up area based on the contrast heat emission seasonal response of a built-up area to solar radiation, and adopted a decision tree classification method for the rapidly accurate extraction of the built-up area. Four study areas, including one major experimental study area (Tangshan) and three verification areas (Minqin, Laizhou, and Yugan) in different climate zones, respectively, were used to empirically establish the overall strategy system, then we specified constrained conditions of this strategy. Moreover, we compared the NDSTI to the current built-up indices, respectively, for extracting the built-up area. The results showed that (1) the new index (NDSTI) exploited the seasonal thermal characteristic variation between the built-up area and other covers in the time series analysis, helping achieve more accurate built-up area extraction than other spectral indices; (2) this strategy could effectively realize rapid built-up area extraction with generally satisfied overall accuracy (over 80%), and was especially excellent in Tangshan and Laizhou; however, (3) it may be constrained by climate patterns and other surface characteristics, which need to be improved from the view of the results of Minqin and Yugan. In summary, the method developed in this study has the potential and advantage to extract the built-up area rapidly from the multi-seasonal thermal infrared remote sensing data. It could be an operative tool for long-term monitoring of built-up areas efficiently and for more applications of thermal infrared images in the future.