This manuscript investigated mathematically magnetized Maxwell fluid over slippery stretching reactive surface with thermophoretic deposition. Similarity transformation was used to recast partial differential equations modeling flow problem to nonlinear coupled ordinary differential equations which were solved using fourth order Range-Kutta method and Newton-Raphson shooting technique. Numerical results were compared with literature-based results and found to be in good accord. Skin friction coefficient, Nusselt number, Sherwood number, velocity profiles, temperature profiles and concentration profiles which are of importance to engineers, were found to be influenced by thermo-physical parameters governing the dynamics of flow. Their effects were illustrated in tabular form and graphically. The study found that increasing Thermophoretic deposition parameter, Momentum slip parameter and Biot number amplified rate of heat transfer but decreased rate of mass transfer and Skin friction coefficients. Thermal Grashof, Solutal Grashof, and Damkohler numbers reduced skin friction coefficients but increased heat and mass transfer rates.