In designing efficient micro devices, particularly microchannels used in cooling electronic components and biomedical microfluidic systems, The foremost application explored is the design and optimization of microchannels employed in the electronic device cooling systems. To possess these microchannels from overheating and damaging their gentle electronic components, exact fluid flow and heat transmission regulation are required. To better design cooling systems, engineers can use mathematical models of Prandtl-Eyring fluid flows to antedate temperature and velocity profiles. The entropy generation also helps in optimizing the design for better fluid transport efficiency. Therefore, the present aim is to characterize the impact of dissipative heat along with magnetization in Prandtl-Eyring non-Newtonian fluid via microchannel. The novelty of the study is the assumption of convective thermal boundary conditions that show efficient heat transport phenomena. A set of similarity rules is adopted for the transformation of the governing equations, and a spectral quasi-linearization technique is then utilized for the solution of the designed miniature. One of the special attractions of the proposed study is the analysis of entropy, which is obtained due to the irreversibility processes within the system. However, irreversibility occurs because of heat transfer, diffusion processes, viscous dissipation, etc. The physical behavior of the pertinent factors is deployed graphically, whereas the validation of the result in a particular case is displayed in tabular form. We use a second law analysis to determine the origins of irreversibility in the thermal system. It is evident that an increase in fluid parameters results in a reduction in entropy generation. An augmentation in the Biot number substantially intensifies the Bejan number. The findings suggest that the magnetic parameter and fluid parameter α have a diminishing effect on velocity.