The coupling coordination between higher education and regional industries is an effective way to enhance the performance of industry-education integration and an important driving force for promoting sustainable economic and social development. This article aims to evaluate the performance level of industry-education integration in higher education from the perspective of coupling coordination between industry and education, and to analyze its sustainable development trends. To achieve this, a framework for the industry-education complex system is constructed based on the theory of coupling coordination, and a performance evaluation model for industry-education integration is established. The "structure-conduct-performance" (S-C-P) analysis paradigm of industrial organization theory is used to design a performance evaluation indicator system, and the entropy weight method is applied to assign weights to the indicator system. Empirical research is conducted on Chongqing based on statistical data from 2000 to 2022. The results show that: (1) During the sample period, the construction effectiveness of industry-education integration in higher education in Chongqing is relatively significant, and the coordination level between regional industries and higher education continues to rise. (2) The orderly development level of the two subsystems of regional industries and higher education alternately rises, jointly promoting the continuous improvement of the performance level of industry-education integration, which is the main driving factor for performance improvement. (3) The stagnation of the coupling strength between regional industries and higher education is a key obstacle to further improving the performance of industry-education integration. Industry-education integration is a systematic project that should be promoted collaboratively from the perspectives of the regional industrial subsystem, higher education subsystem, industry-education complex system, and external environment to continuously enhance the performance level.