The purpose of this study was to assess the effect of non-tariff barriers on Rwanda’s international relations in the East African Community. The study was guided by comparative advantage theory. Descriptive research design was used to achieve the study objectives. The target population for this study constituted 184 officials of Rwanda’s Ministry of Foreign Affairs and International Cooperation from whom a sample of 126 respondents was selected using stratified random sampling method. Data was collected using a questionnaire and was analyzed using descriptive, inferential and thematic content analysis techniques. Analyzed statistical data was presented using tables and charts while qualitative data was documented using narratives. This study concluded that Non-tariff barriers have a positive and significant effect on Rwanda’s International Relations in East African Community. From the findings, this study recommended that the government of Rwanda should continue supporting and advocating for trade liberalization within the EAC. This can be achieved through negotiations within the EAC's Common External Tariff (CET) framework.