Tetrabutylammonium Periodate Research Articles

Solid phase synthesis of oligonucleotides containing 3′-thiothymidine

A 5′- O-monomethoxytritylthymidine-3′- S-thiophosphoramidite (3) has been used to prepare oligodeoxynucleotides containing 3′-thiothymidine on a solid phase support. The intermediate thiophosphites are most efficiently oxidised using tetrabutylammonium periodate.

The oxidative desulphurisation and deselenation at pentacovalent phosphorus catalysed by metalloporphyrins

Manganese (III) mesotetraphenylporphyrin chloride in the presence of tetrabutylammonium periodate has been shown to aid the oxidative desulphurisation and deselenation at pentacovalent phosphorus: the desulphurisation reaction is further aided by the addition of imidazole.

Introduction of a nonaqueous oxidation procedure in the phosphite triester route for oligonucleotide synthesis : Iodobenzene diacetate [formula omitted] or tetrabutylammonium periodate [formula omitted] oxidize phosphite into phosphate under nonaqueous conditions and can be conveniently used in oligodeoxynucleotide synthesis [formula omitted] the phosphite triester route.

Introduction of a nonaqueous oxidation procedure in the phosphite triester route for oligonucleotide synthesis : Iodobenzene diacetate [formula omitted] or tetrabutylammonium periodate [formula omitted] oxidize phosphite into phosphate under nonaqueous conditions and can be conveniently used in oligodeoxynucleotide synthesis [formula omitted] the phosphite triester route.

Mild and selective oxygen atom transfer: nBu 4NIO 4 with metalloporphyrins

Tetrabutylammonium periodate, nBu 4NIO 4, is a potent oxygen atom donor to substrates in the presence of catalytic amount of metalloporphyrin under neutral and homogeneous conditions, the results obtained suggesting the formation of oxometalloporphyrin as an active oxidizing intermediate.

Oxidative decarboxylation of arylacetic acids by means of tetrabutylammonium periodate

Tetrabutylammonium periodate (TBAPI) in refluxing dioxane is able to convert arylacetic acids into the corresponding nor-aldehydes in good yields.