Results Of Test Research Articles

IoT-based health information system using MitApp for abnormal electrocardiogram signal monitoring

Information systems are currently developing very rapidly, and this is inseparable from the role of internet of things (IoT) technology, especially in the world of telemedicine. MitApp is an open-source application that can be used to monitor electrocardiogram (ECG) signals in real-time. The aim of this study is to develop an IoT-based ECG signal monitoring system that utilizes the MitApp application to detect abnormal ECG signals that are characterized by symptoms of cardiac arrhythmias. To process ECG signal data obtained from lead electrode results, the research method utilizes Arduino Uno as a microcontroller. The result is then displayed on the thin film transistor (TFT) layer using the Nextion module. The ESP32 module is used as a Wi-Fi module to send data to the MitApp app on a smartphone. The results showed that the results of the comparison test of ECG signal module data with ECG simulator tools with beats per minute values of 60, 80, 100, 120, and 140 obtained an error rate of 0.05. Based on these results, there is potential to develop this feature and integrate the system with the patient management system to improve the effectiveness of remote monitoring.

Improving student higher order thinking skills using SynecticHOTS-oriented learning model

The achievement of students’ learning outcomes in physics lessons has a low tendency, this is due to various factors, one of which is higher-order thinking skills (HOTS) based learning that has not been fully implemented in the learning process and assessment. This study aimed to determine the differences in the Synectic-HOTS learning model in physics compared to conventional learning models. This study used a quasi-experimental study with a pre-test–post-test nonequivalent control group design. The instrument used in this study is a two-tier test question that contains 20 items of HOTS aspect. The prerequisite test showed that the data was not homogeneous, while the results of the data homogeneity test were stated to be homogeneous. Therefore, a non-parametric test was carried out using the Mann-Whitney U-test. Based on the results of the data analysis, the Asymp. Sig. (2-tailed) for the pre-test was 0.111 and the post-test was 0.001 (p=.000<05). The effect size calculation shows that the Synectic learning model is effective in the medium category. These results indicate that the application of the SynecticHOTS model significantly improves HOTS when compared to conventional learning models. This work can open up insights to teachers about alternative, creative, and effective learning models to improve higher-order thinking skills and student learning outcomes.

Pengaruh Loyalitas Dan Prestasi Kerja Terhadap Promosi Jabatan Pada Koperasi Peternak Garut Selatan

This research departs from a phenomenon regarding employee promotions at the South Garut Breeders Cooperative (KPGS) which tend to be less than optimal. The phenomenon that occurs certainly has a cause, including loyalty and work performance. The purpose of this research is to determine the influence of Loyalty and Work Performance on Position Promotion at KPGS. The population and sample in this research were employees, totaling 39 respondents. The method used in research is descriptive and associative. Based on data analysis, information was obtained that this research instrument was declared valid because it had a value greater than the r table of 0.300 and was declared reliable because it had a Cronbach's alpha value greater than 0.600. From the results of the correlation test, it is clear that Loyalty and Work Performance have a positive influence on Position Promotion with an r value of 0.767 for loyalty and 0.783 for work performance, while the coefficient of determination is 30.2% while the remaining 69.8% is influenced by other factors. which was not examined in this study. Based on hypothesis testing using both the t test and f test, there is a positive and significant influence between loyalty and work performance on job promotion, both partially and simultaneously.

Karakterisasi Struktur Kumarin pada Akar Tumbuhan Langsat (Lansium domesticum Corr.)

Lansium plants produce not only terpenoids as the main constituent but also contain phenolics on the basis of phytochemical analysis. Unfortunately, there are still limited information about phenolic structures from this plants. This study was conducted to identify one of phenolic structures from chloroform fraction of Lansium domesticum root. The chloroform fraction was fractionated and purified by chromatographic techniques such as vacuum liquid chromatography (VLC) and column chromatography (CC) to obtain a coumarin. Additionally, the coumarin structure was characterized by 1H-NMR. The isolated coumarin showed a positive result for the phenolic test with FeCl3 5%. The 1H-NMR spectrum of isolated coumarin revealed chemical shifts at δH 7,60 (1H, d, J = 9,5 Hz), 6,92 (1H, s), 6,84 (1H, s), 6,27 (1H, d, J = 9,5 Hz), 6,14 (1H, s), and 3,95 (3H, s). Based on those results and comparison with literature data, it can be concluded that the isolated coumarin is iso-scopoletin (1)

Аналіз розвитку основних рухових якостей жінок-військовослужбовців в період правового режиму воєнного стану

The article examines and analyzes the development of basic motor qualities in 30 female military members of the Armed Forces of Ukraine under the conditions of the legal regime of martial law. The average age of the participants was 30.8±2.6 years. The aim of the study was to analyze the development of strength, endurance, and coordination abilities. To achieve the stated goal, the following research methods were used: analysis of scientificmethodical literature, analysis of requirements for the development of basic motor qualities in modern combat conditions, summarizing the advanced experience in the theory and organization of physical training of military personnel, pedagogical testing, application of stabilography method, and methods of mathematical statistics. Results. The analysis of endurance development in female military personnel was conducted based on the performance in a 1 km run. The median time to complete the distance was 5.45 min, indicating a low level, and corresponded to only 58 out of 100 possible points on\ the rating scale. It was found that 23.3 % (n = 7) of the participants completed the distance in 6.35 min to 7.14 min and could score only 38 points or less. The median result in the strength endurance exercise test No. 21 was 78 points. It is important to note that among the study participants, no military servicewomen were found who could score the maximum number of points in the range of 95-100 for the performance of any control exercise. Our results indicate that the physical training program requires correction to improve the level of development of basic motor qualities in this category of military personnel. Analysis of static spatial stability of the body in female military personnel, which involved comparing the results of two tests with open and closed eyes, showed statistically significant changes in the majority of the investigated indicators. The center of pressure (CoP) sway length and CoP mean velocity showed an increase of 401.0 mm (p < 0.001) and an increase from 5.4 mm·s-1 t o 9.1 mm·s-1 respectively (p < 0.001) in the test with closed eyes, indicating the significant influence of the visual analyzer on static stability and the dynamics of the body’s CoP sway. Additionally, the quality of balance function, showed a statistically significant decrease to 72.3 % in the test with closed eyes compared to the result of 90.1 % in the test with open eyes (p < 0.001). The comprehensive study of static spatial stability in female military personnel included the Romberg test, which is a classical method for assessing static balance. It was found that 23.3 % of the participants had above-average results, 40 % were within the norm, and 36.7 % showed below-average results, indicating the need for improvement of methods for training static balance in this category. Conclusion. T he o btained r esults o f t he study of the development of basic motor qualities in female military personnel under the conditions of the legal regime of martial law are an important contribution to the scientific discourse and are relevant for the practical activities of military personnel.

Development of a Follow-Up Measure to Ensure Complete Screening for Colorectal Cancer

The current quality performance measure for colorectal cancer (CRC) screening is limited to initial screening. Despite low rates, there is no measure for appropriate follow-up with colonoscopy after receipt of an abnormal result of a stool-based screening test (SBT) for CRC. A quality performance measure is needed. To develop and test a quality performance measure for follow-up colonoscopy within 6 months of an abnormal result of an SBT for CRC. This retrospective quality improvement study examined data from January 1, 2016, to December 31, 2020, with 2018 plus 6 months of follow-up as the primary measurement period to verify performance rates, specify a potential measure, and test for validity, reliability, and feasibility. The Optum Labs Data Warehouse (OLDW), a deidentified database of health care claims and clinical data, was accessed. The OLDW contains longitudinal health information on enrollees and patients, representing a diverse mixture of ages and geographic regions across the US. For the database study, adults from 38 health care organizations (HCOs) aged 50 to 75 years who completed an initial CRC SBT with an abnormal result were observed to determine follow-up colonoscopy rates within 6 months. Rates were stratified by race, ethnicity, sex, insurance, and test modality. Three HCOs participated in the feasibility field testing. Data were analyzed from June 1, 2022, to May 31, 2023. The primary outcome consisted of follow-up colonoscopy rates following an abnormal SBT result for CRC. Reliability statistics were also calculated across HCOs, race, ethnicity, and measurement year. Among 20 581 adults (48.6% men and 51.4% women; 307 [1.5%] Asian, 492 [7.2%] Black, 644 [3.1%] Hispanic, and 17 705 [86.0%] White; mean [SD] age, 63.6 [7.1] years) in 38 health systems, 47.9% had a follow-up colonoscopy following an abnormal SBT result for CRC within 6 months. There was significant variation between HCOs. Notably, significantly fewer Black patients (37.1% [95% CI, 34.6%-39.5%]) and patients with Medicare (49.2% [95% CI, 47.7%-50.6%]) or Medicaid (39.2% [95% CI, 36.3%-42.1%]) insurance received a follow-up colonoscopy. A quality performance measure that tracks rates of follow-up within 6 months of an abnormal SBT result was observed to be feasible, valid, and reliable, with a median reliability statistic between HCOs of 94.5% (range, 74.3%-99.7%). The findings of this observational study of 20 581 adults suggest that a measure of follow-up colonoscopy within defined periods after an abnormal result of an SBT test for CRC is warranted based on low current performance rates and would be feasible to collect by health systems and produce valid, reliable results.

Selective adsorption of soluble starch on the cassiterite surface for effective flotation separation of scheelite from cassiterite

Tungsten and tin are important strategic resources. Scheelite and cassiterite have similar physical and chemical properties and face the challenge of flotation separation. This study proposes soluble starch (SS) as an effective depressant for the flotation separation of scheelite from cassiterite. The depression mechanism of SS was investigated using micro-flotation, zeta potential, total organic carbon, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and time-of-flight secondary ion mass spectroscopy. SS exhibited a good selective depressive effect on cassiterite and was able to efficiently separate scheelite from cassiterite. The results of artificial mixed mineral test showed that the recovery of scheelite and cassiterite were 79.35 % and 9.48 %, respectively and the grade were 70.15 % and 8.11 %, respectively at pH 10. The macromolecular organic depressant SS has abundant hydrophilic groups, such as hydroxyl groups, which cause the material to stably adsorb on Sn active sites on the surface of cassiterite and hinder the adsorption of the collector sodium oleate (NaOL, C17H33CO2Na). The selective adsorption of SS on the surface of cassiterite results in efficient flotation separation of the two minerals.

The Antifungal Effect of Weissella confusa WIKIM51 (Wilac D001) on Vaginal Epithelial Cells Infected by Candida albicans

Vulvovaginal candidiasis (VVC) is a genital infection caused by Candida albicans (C. albicans). Weissella confusa WIKIM51 (Wilac D001) is known to be detected in dandelion kimchi, produce lactic acid, and have an anti−inflammatory ability; however, its diverse antifungal effects have not been studied. Here, we investigated the antifungal effect of Wilac D001 in C. albicans compared to Lactobacillus species on vaginal epithelial cells (VECs). To test the antifungal ability of Wilac D001 against C. albicans on VECs, an adhesion test, pro-inflammatory cytokines (interleukin (IL)-6 and IL-8) analysis, and a disk diffusion test were performed. The acid tolerance test was conducted to investigate the viability of Wilac D001 in various acidic conditions. Lactobacillus reuteri (L. reuteri) and L. rhamnosus were used as positive controls. Wilac D001 showed the capacity to inhibit the colonization of C. albicans by adhering to VECs, with an inhibitory effect similar to that of positive controls. Both pro−inflammatory cytokines including IL−6 and IL−8 concentrations were significantly decreased when Wilac D001 was treated on C. albicans-infected VECs, respectively (p < 0.001). The result of the disk diffusion test indicates that the inhibitory ability of Wilac D001 is comparable to L. reuteri and L. rhamnosus on agar plates infected with C. albicans. Our results demonstrate that Weissella confusa WIKIM51 has antifungal effects against VECs infected by C. albicans.

Abstract 3891: Early real-world experience with repeat multi-cancer early detection (MCED) testing

Abstract Background: An MCED test (Galleri®, GRAIL, LLC, Menlo Park, CA) has been in clinical use since April 2021. We previously reported the results of screening the first ~53,000 individuals in the US with this test from real-world (RW) practice. Here, we report the RW experience with repeated MCED testing in ~5800 individuals. Methods: This MCED test analyzes targeted methylation in cell-free DNA and uses machine learning to detect a Cancer Signal (CS) and determine its Cancer Signal Origin (CSO). We analyzed results returned through August 2023 for those with a “No Cancer Signal Detected” (NCSD) result in Year 1 and an additional consecutive test. We excluded tests from clinical studies and sites that limited data sharing. Systematic collection of outcomes was attempted for all cases with a “CS detected” (CSD) result and continues via a quality assurance (QA) program. Results: In this RW cohort, a second test was ordered in 5794 individuals (58% male, average age=61.3 y, range: 24.0-89.0 and 42% female, average age=60.5 y, range: 23.0-89.0). Median interval between blood draws was 12.9 months, and 81% (4693/5794) were tested 10-18 months after the initial test. Among the 5794, 26 received a CSD result in the second test, of which 20 were within 10-18 months, corresponding to a CSD rate (CSDR) of 0.45% (95% CI 0.31%-0.66%; 26/5794). The CSDR was slightly higher in males (0.50% [0.32%-0.81%; 17/3367]) vs females (0.37% [0.2-0.7%; 9/2427]) and was lower than the Year 1 CSDR of 0.95% (95% CI 0.87-1.0; 510/53,744). The top CSOs reported during second tests were: Lymphoid, Head & Neck, Bladder and Urothelial, Colon & Rectum, Anus. Among the 26 CSD cases, the QA program confirmed 12 clinical outcomes (8 with a cancer diagnosis, 4 with no cancer diagnosis), and 14 cases are still under investigation or without outcomes at this time. Among 8 cases with a confirmed cancer diagnosis, accuracy of the 1st CSO prediction was 100%, and diagnoses reflected invasive cancers across multiple cancer types including anus, colon, head & neck, urothelial tract, ovary, and lymphomas. Staging information was available in 5 cases, including 4 stage I cancers (4/5, 80%; anus, head & neck, lymphoma, bladder) and one stage IV cancer (ovary). Conclusions: A subset of individuals who returned for MCED testing had cancers detected, including cancers without recommended screening, underscoring the potential value of annual screening with this MCED test. There may be systematic differences in this limited population of individuals who returned for repeat screening, reducing the signal detection rate through potential early adopter bias. Clinical data return was incomplete, and confirmed 8 cancers, including 4 stage I cancers. All cancers were found at the predicted CSO, demonstrating the clinical utility of this unique test feature that directs diagnostic work up. Citation Format: Richard Abrams, Rita Shaknovich, Jordan Lipton, Matthew McMillin, Adam Schneider, Matthew Margolis, Xinyi Hou, Yoobin Oh, Victoria Le, Earl Hubbell, Roger Jiang, Jeffrey M. Venstrom, Ora K. Gordon. Early real-world experience with repeat multi-cancer early detection (MCED) testing [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 3891.

Influence of Infarct Morphology and Patterns on Cognitive Outcomes After Endovascular Thrombectomy.

To assess the association of qualitative and quantitative infarct characteristics and 3 cognitive outcome tests, namely the Montreal Cognitive Assessment (MOCA) for mild cognitive impairment, the Boston Naming Test for visual confrontation naming, and the Sunnybrook Neglect Assessment Procedure for neglect, in large vessel occlusion stroke. Secondary observational cohort study using data from the randomized-controlled ESCAPE-NA1 trial (Safety and Efficacy of Nerinetide in Subjects Undergoing Endovascular Thrombectomy for Stroke), in which patients with large vessel occlusion undergoing endovascular treatment were randomized to receive either intravenous Nerinetide or placebo. MOCA, Sunnybrook Neglect Assessment Procedure, and 15-item Boston Naming Test were obtained at 90 days. Total infarct volume, gray matter, and white matter infarct volumes were manually measured on 24-hour follow-up imaging. Infarcts were also visually classified as either involving the gray matter only or both the gray and white matter and scattered versus territorial. Associations of infarct variables and cognitive outcomes were analyzed using multivariable ordinal or binary logistic regression models. Of 1105 patients enrolled in ESCAPE-NA1, 1026 patients with visible infarcts on 24-hour follow-up imaging were included. MOCA and Sunnybrook Neglect Assessment Procedure were available for 706 (68.8%) patients and the 15-item Boston Naming Test was available for 682 (66.5%) patients. Total infarct volume was associated with worse MOCA scores (adjusted common odds ratio per 10 mL increase, 1.05 [95% CI, 1.04-1.06]). After adjusting for baseline variables and total infarct volume, mixed gray and white matter involvement (versus gray matter-only adjusted common odds ratio, 1.92 [95% CI, 1.37-2.69]), white matter infarct volume (adjusted common odds ratio per 10 mL increase 1.36 [95% CI, 1.18-1.58]) and territorial (versus scattered) infarct pattern (adjusted common odds ratio, 1.65 [95% CI, 1.15-2.38]) were associated with worse MOCA scores. Results for Sunnybrook Neglect Assessment Procedure and 15-item Boston Naming Test were similar, except for the territorial infarct pattern, which did not reach statistical significance in multivariable analysis. Besides total infarct volume, infarcts that involve the white matter and that show a territorial distribution were associated with worse cognitive outcomes, even after adjusting for total infarct volume.

Learning styles of the Armed Forces of Ukraine personnel undergoing English language courses

The preferred learning styles according to the Felder-Soloman method of military personnel of the Armed Forces of Ukraine with various military ranks studying English on four-month face-to-face foreign language courses based on the Foreign Languages Education and Research Center of the National Defense University of Ukraine were studied. Active, sensing and visual styles account for approximately 85% of students, while the remaining 15% have reflective, intuitive and verbal styles. The advantage of the sequential over global style is about 75%. No correlation was found between individual learning preferences, the results of the English language entrance test (four tests - listening, writing, reading and speaking), and officer ranks. The method of two-stage cluster analysis shows that respondents form two clusters (Silhouette cluster quality - 0.5-0.6) of approximately the same size according to the level of language proficiency. The most influential factor for cluster formation is the results of listening. Military personnel learning styles were compared with literature data on students' learning styles from 12 fields of study. Two fields (military and natural sciences) demonstrate the preferences toward four styles in all four dimensions; preferences in 2 directions (sensing and visual) and balance in the other two are characteristic of six fields of study. Four other studied fields have a propensity in only one dimension (visual perception of information).

Establishing and verifying the threshold value of HLA mixed antigen reagent screening test results

Objective: To establish the threshold value of human leukocyte antigen (HLA) mixed antigen reagent screening test results, and to verify it by HLA single antigen reagent confirmation test results. Methods: The results of 2 255 serum samples tested for HLA antibodies by HLA mixed antigen reagent in the department of HLA Laboratory, the First Affiliated Hospital of Soochow University from October 2017 to December 2021 were retrospectively analyzed. Among them, 1 139 samples were also tested by single antigen HLA Class-Ⅰ reagent and 1 116 samples were also tested by single antigen HLA Class-Ⅱ reagent. Based on the same antigens coated with both reagents, the Mean Fluorescence Intensity (MFI) and Nomalized Background ratio (NBG ratio) of 12 HLA Class-Ⅰ beads and 5 HLA Class-Ⅱ beads in the HLA mixed antigen reagent and the MFI of 77 anti-HLA class-Ⅰ antibodies and 35 anti-HLA class-Ⅱ antibodies detected by HLA single antigen reagent were recorded. The MFI and NBG ratio of HLA mixed antigen reagent beads in 1 139 or 1 116 samples were segmented according to the positive rate of antibodyies detected by the single antigen reagent corresponding to the antigens coated with each HLA mixed antigen reagent bead, and the results of the HLA mixed antigen screening test were verified by the HLA single antigen reagent confirmation test. Results: The threshold values of MFI and NBG ratio of HLA mixed antigen reagent's 17 beads were established. The MFI of No. 1 to No. 17 beads of HLA mixed antigen reagent ranged from 26.86 to 21 925.58, and the NBG ratio ranged from 0 to 434.65. According to the positive detection rate of HLA single antigen reagent corresponding to the coated antigens, the MFI and NBG ratio of the beads of HLA mixed antigen reagent were divided into positive interval, suspicious positive interval, suspicious negative interval and negative interval. The positive rates of anti-HLA class-Ⅰ antibodies by HLA mixed antigen reagent and single antigen HLA Class-Ⅰ reagent were 87.5% (997/1 139) and 66.3% (755/1 139). The positive rates of anti-HLA class-Ⅱ antibodies were 63.4% (707/1 116) and 44.9% (501/1 116). In the samples with suspicious negative, suspicious positive and positive results of HLA class-Ⅰ、Ⅱ antibodies detected by HLA mixed antigen reagent, the positive detection rates of single antigen HLA Class-Ⅰ reagent were 14.9% (17/114), 41.3% (145/351) and 91.3% (590/646), respectively. The positive detection rates of single antigen HLA Class-Ⅱ reagent were 15.5% (58/375), 26.5% (81/306) and 88.8% (356/401), respectively. Conclusions: In this study, the threshold values of MFI and NBG ratio of HLA mixed antigen reagent screening test are established, and the threshold values are verified by the results of HLA single antigen reagent confirmation test. HLA mixed reagent screening test can be used for screening of HLA antibodies, and if necessary, it should be combined with HLA single antigen confirmatory test for clinical detection of HLA antibodies.

Auditory Spatial Illusion – A Psychoacoustic Study in Young Adults

The Franssen illusion, or Franssen effect (FE), is one of the auditory spatial illusions. Few studies have explored the FE, and the mechanisms underlying it remain unknown. The present study was conducted to clarify the FE occurrence with different tasks and presentation modes in young adults. It also sought to investigate possible neurophysiological similarities between interaural time difference (ITD) cue processing and FE perception. FE perception was evaluated using two different tasks and two presentation modes (i.e., insert phones and loudspeakers). Sound reflections (reverberation) were presented in the diffuse field (loudspeaker mode). ITD performance was investigated using different stimuli delivered via insert phones. No significant difference between the two FE perception tasks was found ( F 1,25 = 0.138, p = 0.713). However, the FE perception showed a significant difference between the two presentation modes (F 1,25 = 434.03, p < 0.001). Spearman’s correlation did not reveal a significant relationship between FE perception and ITD scores ( p > 0.05). The current findings show the importance of reverberation in the FE occurrence. Also, the non-significant correlation between the results of the behavioral binaural temporal resolution test and FE perception in young people with normal temporal resolution may indicate that room reflections (reverberation) complicate the ability to process ITDs (rather than poor ITD processing for the “steady state” portion of signal).

Aspects Affecting the Quality of Masonry Buildings and Innovations in Masonry

The construction industry is undergoing another revolution, including the field of masonry construction. New materials and products for masonry are constantly being developed and construction details and implementation procedures are being resolved. Digitization and the introduction of automation in the masonry process (in prefabrication halls or on-site robotic bricklaying) are also an integral part of the development of the masonry construction industry. The topic of the following paper is a summary of problematic construction details of masonry buildings, i.e., the solution of the plinth console, the solution of the building opening, the bearing of lintels on the masonry and the bearing of the ceiling structure on the masonry wall. The results of laboratory tests are presented – the load-bearing capacity of the jamb of the building opening (accessory bricks / cut bricks in the jamb) and the load-bearing capacity of the lintel placed on the accessory edge brick. Furthermore, the paper deals with the construction of masonry buildings in the 21st century, including the first results of a compressive load test on masonry walls made of precast small-format units. The conclusion of the paper points out the importance of correct design details of masonry buildings before their application (programming) in software controlling the automated masonry process.

Evaluating an Instructional Intervention for Research Data Management Training

Objective – At a large research university in Canada, a research data management (RDM) specialist and two liaison librarians partnered to evaluate the effectiveness of an active learning component of their newly developed RDM training program. This empirical study aims to contribute a statistical analysis to evaluate an RDM instructional intervention. Methods – This study relies on a pre- and post-test quasi-experimental intervention during introductory RDM workshops offered 12 times between February 2022 and January 2023. The intervention consists of instruction on best practices related to file-naming conventions. We developed a grading rubric differentiating levels of proficiency in naming a file according to a convention reflecting RDM best practices and international standards. We used manual content analysis to independently code each pre- and post-instruction file name according to the rubric. Results – Comparing the overall average scores for each participant pre- and post-instruction intervention, we find that workshop participants, in general, improved in proficiency. The results of a Wilcoxon signed-rank test demonstrate that the difference between the pre- and post-test observations is statistically significant with a high effect size. In addition, a comparison of changes in pre- and post-test scores for each rubric element showed that participants grasped specific elements more easily (i.e., implementing an international standard for a date format) than others (i.e., applying information related to sequential versioning of files). Conclusion – The results of this study indicate that developing short and targeted interventions in the context of RDM training is worthwhile. In addition, the findings demonstrate how quantitative evaluations of instructional interventions can pinpoint specific topics or activities requiring improvement or further investigation. Overall, RDM learning outcomes grounded in practical competencies may be achieved through applied exercises that demonstrate immediate improvement directly to participants.

Automatic Optimization of JWL‐Miller parameters of HMX‐based aluminized explosive based on genetic algorithm

AbstractThe calibration of JWL‐Miller equation of state (EOS) parameters for aluminized explosive is a cumbersome but important work in explosive evaluation. Manual calibration is usually adopted while the work may be tedious and the optimal results may be unachievable. An automatic calibrating method was established to optimize this procedure based on genetic algorithm program and finite element software. Optimal JWL‐Miller EOS parameters were achieved by iterative calculation calibrating with cylinder test results and underwater‐explosion experiment results. Cylinder test results were adopted to illustrate the initial phase of explosion, and underwater explosion experiments were conducted to calibrating the Miller term of the equation of state. The results showed that the error between cylinder test and simulation result was less than 1 %, the error of underwater explosion impulse between test and simulation results was less than 3.73 %. The optimized parameters of JWL‐Miller EOS will be useful in the numerical simulation research of aluminized explosives.

Effect of robot-assisted gait training on motor dysfunction in Parkinson's patients:A systematic review and meta-analysis.

Robot-assisted gait training (RAGT) has been reported to treat motor dysfunction in patients with Parkinson's disease (PD) in the last few years. However, the benefits of RAGT for treating motor dysfunction in PD are still unclear. To investigate the efficacy of RAGT for motor dysfunction in PD patients. We searched PubMed, Web of Science, Cochrane Library, Embase, CNKI, Wanfang, Chinese Biomedical Literature Database (CBM), and Chinese VIP Database for randomized controlled trials investigating RAGT to improve motor dysfunction in PD from the databases' inception dates until September 1, 2022. The following outcome indexes were employed to evaluate motor dysfunction: the Berg Balance Scale (BBS), Activities-specific Balance Confidence Scale (ABC), 10-Meter Walk Test gait speed (10-MWT), gait speed, stride length, cadence Unified Parkinson Disease Rating Scale Part III (UPDRS III), 6-Minute Walk Test (6MWT), and the Timed Up and Go test (TUG). The meta-analysis was performed using the proper randomeffect model or fixed-effect model to evaluate the difference in efficacy between the RAGT and the control groups. The Cochrane Risk of Bias Tool was used for the included studies and Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) was used to interpret the certainty of the results. The results consisted of 17 studies comprising a total of 670 participants. Six hundred and seven PD patients with motor dysfunction were included: 335 in the RAGT group and 335 in the control group. This meta-analysis results established that when compared with the control group, robot-assisted gait training improved the BBS results of PD patients (MD: 2.80, 95%CI: 2.11-3.49, P< 0.00001), ABC score (MD: 7.30, 95%CI: 5.08-9.52, P< 0.00001), 10-MWT (MD: 0.06, 95%CI: 0.03-0.10, P= 0.0009), gait speed (MD: 3.67, 95%CI: 2.58-4.76, P< 0.00001), stride length (MD: 5.53, 95%CI: 3.64-7.42, P< 0.00001), cadence (MD: 4.52, 95%CI: 0.94-8.10, P= 0.01), UPDRS III (MD: -2.16, 95%CI: -2.48--1.83, P< 0.00001), 6MWT (MD: 13.87, 95%CI: 11.92-15.82, P< 0.00001). However, RAGT did not significantly improve the TUG test result of patients with PD (MD =-0.56, 95% CI: -1.12-0.00, P= 0.05). No safety concerns or adverse reactions among robot-assisted gait training patients were observed. Even though RAGT can improve balance function, walking function, and gait performance and has demonstrated positive results in several studies, there is currently insufficient compelling evidence to suggest that it can improve all aspects of lower motor function.

Hubungan Tingkat Kecemasan dengan Kualitas Tidur dalam Menyusun Skripsi pada Mahasiswa Tingkat Akhir Prodi Sarjana Keperawatan Universitas Muhammadiyah Sukabumi

Hubungan Tingkat Kecemasan dengan Kualitas Tidur dalam Menyusun Skripsi pada Mahasiswa Tingkat Akhir Prodi Sarjana Keperawatan Universitas Muhammadiyah Sukabumi

Pengaruh Jumlah Penduduk, Tingkat Pendidikan, Inflasi dan Pengangguran terhadap Tingkat Kemiskinan di Kabupaten Flores Timur Tahun 2013-2022

This study aims to determine the effect of population, education level, inflation and unemployment on poverty levels in East Flores District partially and simultaneously. This study uses quantitative research methods with the analysis technique used is the semilog linear regression model. To calculate the linear regression equation, the semilog model data must meet the classical assumption test and hypothesis test. This is evidenced by the results of the parametric significant test (t test). The coefficient value of the population variable is 2,322 with tcount&lt;ttable (2,325&gt;2,015), the coefficient value of the education level variable is -14.502 with tcount&lt;ttable (-2.307&lt;2,015), the inflation variable coefficient value is -0.784 with tcount&lt;ttable (-4.781&lt;2,015) and the coefficient value of the unemployment variable is 3.736 with tcount&gt;ttable (3.401&gt;2,015). Then for the F test, the value of Fcount&gt;Ftable(7.642&gt;5.19) is obtained. Based on the results of the calculation of the t test, it can be concluded that the population variable has no effect on the poverty level because the addition of the population is followed by a higher increase of other factors which are indicated to reduce poverty such as increased income in the community, causing a high poverty rate. goverment to finance his education thereby reducing the poverty rate in East Flores Regency. Inflation has a negative effect on the level of poverty, even though there is inflation, the poor are still able to meet their needs and unemployment affects the level of poverty because the unemployed are people who do not have jobs and income so they cannot make ends meet. Based on the F test that population, education level, inflation and unemployment simultaneously affect the level of poverty in East Flores Regency.

Pengaruh Kemampuan Kerja, Disiplin Kerja Dan Pengawasan Terhadap Kinerja Karyawan Pada PB Swalayan 21 Kota Metro

This research aims to analyze the influence of Work Ability, Work Discipline and Supervisionon employee performance. This type of research is quantitative research with a population of54 employees registered at PB Swalayan 21 Metro City, only 48 samples used that fit thepredetermined criteria. The data used is secondary data from the distribution ofquestionnaires in the form of a list of questions with several alternative answers forrespondents. The statistical test used to test the hypothesis is a multiple linear regressionanalysis test and tested using the statistics packages for the social science (SPSS) version 21program. Based on the results of the statistical test, it shows that Work Ability, WorkDiscipline, Supervision have a positive and significant influence on performance. employee.