Abstract: Termiticidal potential of methanol and aqueous leaves extract of Jatropha gossypifolia Linn. were studied against Odontotermes obesus. The plant leaves were dried, powdered and extracted with methanol and aqueous solvent in soxhlet apparatus for 24 hrs. The 20 termites were exposed to various concentrations from 9.0 to 14.5 mg/ml) of methanol and of aqueous plant extract of Jatropha gossypifolia and percent mortality were recorded after 24 hrs. The termiticidal activity of leaves extract of Jatropha gossypifolia were (LC10 = 9.8220 mg/ml, LD50 = 10.093, LC90 =12.667 mg/ml) in methanol and (LC10 = 11.984, LC50 = 13.195, LC90 =14.531 mg/ml) in aqueous solvent respectively. Results revealed that the mortality was increased with increasing in concentration of the plant extracts. The methanol solvent extract of Jatropha gossypifolia showed higher termiticidal property against Odontotermes obesus. Statistical variance, 95% confidence limits and regression equations are presented.