Term Usage Research Articles

A Proposal: Human Factors Related to the User Acceptance Behavior in Adapting to New Technologies or New User Experience

We are aware of the tremendous growth of new mobile phones released in the market every year. The increase in the users’ needs with respect to the new devices is not to be ignored as well. Each product has so many brands with n-number of models and versions.The way the users choose to buy these products is perplexing. For example,decision made to buy a new mobile or change to new brand or even continuing the same brand is not an easy task. The user acceptance for any new behavior is very complex. This paper explores all the possible human factors connected to either pleasant or unpleasant user experiences. Various researchstudies discovered that loyalty of the users for a particular brand plays an important role for the success of the product. Long- term usage of the product by a user would have a negative impact, as the user is not willing to switch to other brands and this has a positive impact on the companies. User memory, expectations and experiences are closely knit to understand the user acceptance for choosing a product. A positive emotion such as pleasant user experience is significant because users recommend the products to others based on these emotional experiences. Age plays an important role with respect to user experience. Old age users were not enthusiastic in going for a change as they preferred to continue with the same technology. Cultural aspects of users are interesting to know in understanding the product purchases. There was biased information regarding user’s visual attractiveness and long- term usage memory. Certain studies explored UX curve and user burden scale that was used to analyze user experiences. It was interesting to know sensory characteristics formed a base for both pleasant and unpleasant user experiences. This research will help companies of mobile devices in identifying the various factors (both positive and negative) related to user experiences and behavior. Future research will be conducted in the areas of short-term user experience and in areas where illiteracy prevail. This study will help the companies to improve their product better based on customer satisfaction.

Anti-bacterial and multi-functional smart wearable sensor based on organo-hydrogel for diagnosis of the anterior cruciate ligament injuries, and sensing glove for rehabilitation of joints motion

Stretchable multi-functional electronic skin devices capable of interface with parts of human body and/or internal organs to diagnose the anterior cruciate ligament (ACL) injuries and rehabilitation of human joint motion are attractive candidates for next-generation wearables biomedical devices, soft robots, and the Internet of Things (IoT). Such devices need to be of excellent mechanical property, anti-freezing, antibacterial, biocompatible to be comfortable to wear for long term usage and accommodate strains from repeated movement and prevent skin irritation. To address this need, we introduced conductive organo-hydrogels based on silver quantum dots (COH@AgQDs) as multi-functional stretchable sensor with outstanding high-performance diagnostic capabilities. We demonstrated a prototype from the developed sensors integrated into a wirelessly Arduino board and a smartphone was selected to transmit data which offers promising wireless system for rehabilitation after surgeries. Additionally, the developed device has ability to differentiate between ACL injury and healthy knee with different pattern shapes and high sensitivity. Moreover, the flexible sensor can inhibit the growth of bacteria (Escherichia coli (E-coli)) and Staphylococcus aureus (S. aureus) and protect human health for long-term use. It exhibited outstanding anti-freezing property (−53 °C), antibacterial, self-healing, robust mechanical property (strain 420% at stress 96 kPa), and high linearity.

Bioactive peptides from meat: Current status on production, biological activity, safety, and regulatory framework

By-products of the meat processing industry which are often discarded as waste are excellent protein substrates for producing bioactive peptides through enzymatic hydrolysis. These peptides have tremendous potential for the development of functional food products but there is scanty information about the regulations on bioactive peptides or products in various parts of the world. This review focuses on the diverse bioactive peptides identified from different meat and meat by-products, their bioactivity and challenges associated in their production as well as factors limiting their effective commercialization. Furthermore, this report provides additional information on the possible toxic peptides formed during production of the bioactive peptides, which enables delineation of associated safety and risk. The regulatory framework in place for bioactive peptide-based foods in different jurisdictions and the future research directions are also discussed. Uniform quality, high cost, poor sensory acceptance, lack of toxicological studies and clinical evidence, paltry stability, and lack of bioavailability data are some of the key challenges hindering commercial advancement of bioactive peptide-based functional foods. Absorption, distribution, metabolism and excretion (ADME) studies in rodents, in vitro genotoxicity, and immunogenicity data could be considered as absolute pre-requisites to ensure safety of bioactive peptides. In the absence of ADME and genotoxicity data, long term usage to evaluate safety is highly warranted. Differences in legislations among countries pose challenge in the international trade of bioactive peptides-based functional foods. Harmonization of regulations could be a way out and hence further research in this area is encouraged.

Removal and recovery of ammonia from simulated wastewater using Ti3C2Tx MXene in flow electrode capacitive deionization

Flowing electrode capacitive deionization systems (FE-CDI) have recently garnered attention because of their ability to prevent cross contamination and operate in uninterrupted cycles ad infinitum. Typically, FE-CDI electrodes suffer from low conductivity, reducing deionization performance. Utilization of higher mass loadings to combat this leads to poor rheological properties. Herein, Ti3C2Tx MXene was introduced as 1 mg mL−1 slurry electrodes in an FE-CDI system for the removal and recovery of ammonia from simulated agricultural wastewater. The electrode performance was evaluated by operating the FE-CDI system with a feed solution of 500 mg L−1 NH4Cl running in batch mode at a constant voltage of 1.20 and −1.20 V in charging and discharging modes, respectively. Despite the low loading, Ti3C2Tx flowing electrodes showed markedly improved performance, achieving 60% ion removal efficiency in a saturation time of 115 min with an adsorption capacity of 460 mg g−1. To understand the high adsorption performance of the electrodes, physiochemical and structural analysis was done via a variety of characterization techniques such as SEM, TEM, XRD, DLS, and Raman spectroscopy. Cyclic voltammetry and galvanostatic charge/discharge profiles were obtained to evaluate the electrochemical properties of the electrodes. The system proved to be an energy-saving technology by exhibiting a charge efficiency of 58–70% while operating at an energy consumption of 0.45 kWh kg−1. A 92% regeneration efficiency showed that the electrodes were stable and suitable for long term and scalable usage. The results demonstrate that MXenes have the potential to improve the FE-CDI process for energy-efficient removal and recovery of ammonia.

Microbial-induced carbonate precipitation prevents Cd2+ migration through the soil profile

Cadmium (Cd)-containing wastewater has been used to irrigate agricultural land. However, long term usage has resulted in the accumulation of Cd in the soil systems, which can eventually leach into the aquifer, contaminating groundwater. Microbial-induced carbonate precipitation (MICP), an economical and effective method, was used to block the in situ migration of Cd2+ in the soil profile. The results of the laboratory experiments showed that the maximum Cd2+ adsorption capacity of the soil exposed to MICP (8.92 mg/g) was higher than that of soil without MICP (7.12 mg/g). The Thomas model provided a good fit for the Cd2+ migration process in soil exposed to MICP (R2 > 0.96), and Cd2+ was trapped more effectively by soil exposed to MICP than by soil alone. Further testing showed that the Cd2+ retention time in the MICP soil column increased with increasing soil urea content and pH but decreased with increasing flow rate. Soil physico-chemical properties showed that the MICP process increased the soil particle size and Cd capacity and decreased the proportion of exchangeable Cd in the soil. Scanning electron microscopy and X-ray diffraction analyses confirmed the generation of CdCO3 in the MICP soil column. The findings of this study indicate that MICP can be effectively used to immobilize Cd2+ and prevent its migration in the soil profile.

P35-4 Corticosteroid switch in metastatic castration-resistant prostate cancer treated with abiraterone: A systematic review

Abiraterone acetate (AA) combined with prednisone (P) has been clinically approved for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC). However, long term usage of prednisone could induce AA resistance demonstrated by PSA progression. Subsequently, recent studies described that corticosteroid switch to dexamethasone (D) is associated with increased AA sensitivity and PSA decline in patients previously treated with AA+P. Therefore, this study aims to review survival improvement in term of PSA decline after a steroid switch to dexamethasone.

Formulation and Evaluation of an Antifungal Ointment Containing Zingiber officinale Roscoe (Zingiberaceae) Essential Oil as Active Principle

The increase incidence of fungal infections, the resistance of fungal strains to existing drugs and the toxicity assimilated to long term usage of antifungal drugs as prompted the search of new alternative from natural source. In this study we have evaluated the antifungal properties of the essential oil of the rhizome of Z. officinale, a plant known for its various biological properties and used in food industry as spice. An antifungal ointment with Z. officinale essential oil as active principle was also formulated and its antifungal properties evaluated. GC/MS analysis identified Zingiberene (22.36%), 1.8-cineole (15.54%), geranial (11.91%), camphene (11.09%) and geraniol (8.75%) as the main constituents of Z. officinale essential oil obtained by hydrodistillation. The oil showed a significant antifungal activity against clinical isolate of Candida krusei with MIC 800 ppm by microdilution method. The formulated ointment containing 10 % glycerol, 60 % vaseline, 8 % hydrosol, 20% lanolin and 2% Zingiber officinale essential oil (Formule E1) was found to follow pharmaceutical standards according to European Pharmacopeia and also showed good antifungal properties

P-438 Fertility outcomes in male cancer recipients of hematopoietic cell transplantation who stored their semen for fertility preservation

Abstract Study question What are the prevalence estimates of post-hematopoietic cell transplantation (HCT) natural conceptions or after ART using stored semen? Summary answer Natural live birth rate following HCT can be estimated at 9% (95%CI:4-22%) but can be increased to 58% (95%CI:43-72%) with the use of frozen semen. What is known already With the improvements and expanding indications of HCT, the number of adult male cancer survivors who received HCT is increasing. These men face the risk of treatment-induced infertility and are generally recommended to store their semen prior to embark in HCT. However, information on long term usage and on effectiveness of frozen sperm samples in this specific population is not well defined. Study design, size, duration All male cancer recipients of autologous or allogeneic transplantation who cryopreserved semen between 1987 and 2016 in the biobank of the Assisted Reproductive Technology Unit of the Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico in Milan were considered. Information was obtained from patients’ charts or through active investigation. The main studied topics included results from semen analyses, attempt to parenthood, use of stored spermatozoa and both natural and Assisted Reproductive Technique (ART) mediated conceptions. Participants/materials, setting, methods The study is restricted to men who met the following eligibility criteria: i) semen cryopreserved for fertility preservation between 1987 and 2016; ii) post-banking follow-up documenting HCT iii) survival of at least 5 years from HCT. Main results and the role of chance One-hundred and two HCT survivors were selected. The median [IQR] age at sperm banking was 29 [23-34]. About half of subjects had autologous HCT (n = 50), the remaining 52 received allogenic HCT. Lymphomas were the most frequent indications. The median spermatozoa concentration at the time storage was 39 [7-85] millions/ml. Fifty-four (53%) men performed a post-treatment sperm analysis and azoospermia was documented in 45 of them (83%, 95%CI: 71-91%). The remaining nine showed viable spermatozoa, of whom six had severe oligospermia (concentration <1 million/mL). The other three had semen concentration >5 Millions/ml, compatible with a natural conception. Overall, based on semen analyses, one could infer the necessity to use ART in 51 out of 54 subjects, corresponding to 94% (95%CI: 85-98%). Forty-three of the 102 included men (42%) sought childbearing. Four had a natural live birth (9%, 95%CI: 4-22%). Thirty-three used their cryopreserved sperm samples, corresponding to 32% (95%CI: 24-42%) of the whole cohort. Twenty-one of these 33 men had at least one live birth (64%, 95%CI: 47-78%). Finally, six men seeking pregnancy and who did not conceive have not used their frozen semen. Overall, 25 out of 43 men interested in fatherhood had a live birth (58%, 95%CI: 43-72%). Limitations, reasons for caution Limitation of our study is missing detailed information on status of illness and comorbidities (in particular the frequency of Graft-versus host disease) and lack precise information on the myeloablative regimen used. Furthermore, our sample size is not very large and therefore the 95%CI of the reported proportions are wide. Wider implications of the findings Autologous or allogeneic HCT induces infertility in a very high percentage of patients. These findings support the need to prioritize sperm preservation before HCT also in cancer patients who are not candidate for HCT at first instance but who may need this treatment for failure of first line treatments. Trial registration number not applicable

Identifying Medication-Related Intents From a Bidirectional Text Messaging Platform for Hypertension Management Using an Unsupervised Learning Approach: Retrospective Observational Pilot Study

BackgroundFree-text communication between patients and providers plays an increasing role in chronic disease management, through platforms varying from traditional health care portals to novel mobile messaging apps. These text data are rich resources for clinical purposes, but their sheer volume render them difficult to manage. Even automated approaches, such as natural language processing, require labor-intensive manual classification for developing training data sets. Automated approaches to organizing free-text data are necessary to facilitate use of free-text communication for clinical care.ObjectiveThe aim of this study was to apply unsupervised learning approaches to (1) understand the types of topics discussed and (2) learn medication-related intents from messages sent between patients and providers through a bidirectional text messaging system for managing participant blood pressure (BP).MethodsThis study was a secondary analysis of deidentified messages from a remote, mobile, text-based employee hypertension management program at an academic institution. We trained a latent Dirichlet allocation (LDA) model for each message type (ie, inbound patient messages and outbound provider messages) and identified the distribution of major topics and significant topics (probability >.20) across message types. Next, we annotated all medication-related messages with a single medication intent. Then, we trained a second medication-specific LDA (medLDA) model to assess how well the unsupervised method could identify more fine-grained medication intents. We encoded each medication message with n-grams (n=1-3 words) using spaCy, clinical named entities using Stanza, and medication categories using MedEx; we then applied chi-square feature selection to learn the most informative features associated with each medication intent.ResultsIn total, 253 participants and 5 providers engaged in the program, generating 12,131 total messages: 46.90% (n=5689) patient messages and 53.10% (n=6442) provider messages. Most patient messages corresponded to BP reporting, BP encouragement, and appointment scheduling; most provider messages corresponded to BP reporting, medication adherence, and confirmatory statements. Most patient and provider messages contained 1 topic and few contained more than 3 topics identified using LDA. In total, 534 medication messages were annotated with a single medication intent. Of these, 282 (52.8%) were patient medication messages: most referred to the medication request intent (n=134, 47.5%). Most of the 252 (47.2%) provider medication messages referred to the medication question intent (n=173, 68.7%). Although the medLDA model could identify a majority intent within each topic, it could not distinguish medication intents with low prevalence within patient or provider messages. Richer feature engineering identified informative lexical-semantic patterns associated with each medication intent class.ConclusionsLDA can be an effective method for generating subgroups of messages with similar term usage and facilitating the review of topics to inform annotations. However, few training cases and shared vocabulary between intents precludes the use of LDA for fully automated, deep, medication intent classification.International Registered Report Identifier (IRRID)RR2-10.1101/2021.12.23.21268061

Real work experiences, practices and adverse events associated with long term usage of N95 respirators during the COVID-19 pandemic – A cross-sectional survey amongst Indian physicians

Introduction: Doctors are at increased risk of exposure to SARS-CoV-2 virus, and use of N95 respirators has emerged as a key preventive measure. This study aimed to study the real-world experiences, practices and adverse effects of N95 respirator usage amongst doctors of India. Methods: An analytical, cross-sectional online survey was conducted between November 2020 and January 2021. Real-world usage characteristics of N-95 respirators were collected via a pre-validated questionnaire (use, reuse, wearing and disposal practices) and compared amongst different sub-cohorts. Results: 453 responses from physicians were analyzed. The most important adjunct to the N95 respirator perceived by the respondents was the full-face shield (81.9%). Most doctors had to purchase extra mask per month (median = 5) and this was more amongst the medical specialties (p = 0.006). Highest mean VAS scores for adverse events were reported for breathing on exertion (6.62 ± 2.25) and ear pain (6.34 ± 2.69). VAS ear pain was higher in ages < 40 and doctors working in the public sector (p = 0.017 and p = 0.019 respectively). Conclusion: There are many inadequacies with regard to proper mask removal and doffing techniques among doctors in India. The major adverse effects faced by the doctors on prolonged mask usage were ear pain and breathing on exertion. However, it can be noted in spite of these deficiencies; there is generally good adherence to protocols and good practices of mask usage in hospital setting.

Evaluation of therapeutic efficacy of tranexemic acid compared to kligman formula in the management of melasma

Facial melanoses (FM) are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Melasma is an acquired non-inflammatory hypermelanosis of multifactorial etiology with significant cosmetic deformity. Different treatment modalities have been utilized in different studies with varying outcomes. Recent clinical trials with Tranexamic acid are promising. : To compare the therapeutic efficacy of Tranexamic acid (TXA) in 2 different modalities with Modified Kligman formula in the management of melasma. : This is a prospective, randomised, open‑label study with a sample size of 45 patients of melasma fulfilling inclusion and exclusion criteria were randomly divided into 3 groups, 15 in each group. Group A: At home, daily applicatioin of modified kligman formula at night for 3 months. Group B: 12 sittings of microneedling followed by Tranexamic acid application was done weekly. Group C: 12 sittings of intralesional tranexamic acid (4mg/ml) was done weekly. Clinical images and dermoscopic images were taken at each visit including modified Melasma Area Severity Index (MASI) scoring, patient global assessment and physician global assessment to assess the clinical response. : Modified kligman formula group showed 42% improvement in MASI score by the end of 12 weeks, where as intralesional Tranexamic acid group showed 36% improvement followed by 30% improvement in microneedling with Tranexamic acid group. When statistically compared with Analysis of variance (ANNOVA) test, there was no significant difference (p=0.62) between three groups. But in individual groups there was significant difference (p<0.05) in MASI at 0 weeks and 12 weeks. Dermoscopic images showed perilesional hypopigmentation and telangiectasias with modified kligman formula, which was not seen with Tranexamic acid. Patient assessment score revelaed satisfaction with modified kligman formula in view of home application and pain during microneedling and microinjections which was not there in this group. : Modified kligman formula is found to be superior in the treatment of melasma, because of the synergistic activity of its components. But it has its own demerits of long term usage. Hence, Tranexamic acid which showed comparable results with kligman formula can be used either as a primary modality or as an adjuvant supportive therapy for maintanence.

Assessment of Mechanical Properties of Aged Composite Propellant Using Non‐Destructive Indentation Technique in Solid Propellant Rocket Motor

AbstractAgeing study of composite propellant is one of the important aspects for the long term usage of a solid propellant rocket motor (SPRM). The assessment of mechanical properties is essential to predict the structural performance of rocket motors before its flight test. Mostly, the study of ageing behavior of composite propellant is limited to sample level which is subjected to either for normal ageing or accelerated ageing. In the present study, an attempt was made to assess the aging behavior of HTPB based composite propellant at full scale rocket motor level using a non‐destructive indentation technique. The mechanical properties of naturally aged HTPB based composite propellant samples were comprehensively studied by both Universal Testing Machine (UTM) and indentation technique. The mathematical correlation was developed using least square method between UTM and indentation data. An attempt was made to establish the method to assess the aging behavior of composite propellant by indentation technique directly. The developed correlation was validated on aged composite propellant samples. Further, indentation technique was used to assess the mechanical properties of the propellant of in‐flight fielded SPRM which was 11 years old.

The CORRELATION BETWEEN PARENTING STYLES AND SMARTPHONE ADDICTION AMONG PRIMARY SCHOOL STUDENTS IN INDONESIA

Introduction: Long term usage of smart phones will influence the physical and psychological conditions of children. Parents need to supervise the use of smart phones to overcome the impact of playing smart phones. The purpose of this study was to determine correlation of parenting styles with children's smart phone addiction rates in Indonesia. Materials and Methods: The design of the study used correlative analytics with a cross-sectional approach. The population was elementary school students at grades four, five, and six on Islamic elementary school in Indonesia. The Proportionate stratified random sampling technique was applied to get the sample and got 70 students as the respondents. The data were collected by using the Parenteral Authority Questionnaire (PAQ) and Smartphone Addiction Questionnaire. Data analysis using the Chi-Square test. Results: Most students had parents with a democratic parenting style (48.6%), and most students experienced moderate addiction (54.3%). The chi-Square test shows a relationship between parenting with smart phone addiction and the results of ρ = 0.042. Conclusion: This study indicated that proper parenting style could reduce the incidence of smart phone addiction, so parents need to applied effective parenting. For the school to always provide direction and guidance in the form of socialization to students about the effects of excessive smart phone use. The nursing profession, especially the local community health centers, is expected to be able to collaborate with schools to minimize the incidence of smartphone addiction by providing socialization about the impact of smartphone use.

Correlation of term usage and term indexing frequencies

There have been several studies on the distributions of index terms, title terms, authors and other elements used in searching bibliographic databases. What is needed is to relate this information of the actual usage of terms in searching. This study uses data from monitoring the actual usage of terms in an online catalog at the School of Library and Information Science at the University of Western Ontario. Every time a term was used in a search expression, a count in the dictionary file was updated. If a word was not in the dictionary it was added. In this way we can see which words are in the catalog and not searched and also those which were searched but not in the dictionary. As a check on other studies the rank distribution of terms used in searching was checked and found to be of a general Zipf type.
 The main interest was to check if high frequency terms in the catalog were used frequently in searching. Several measures of this were tried. First the regular scatterplot of frequency of use in the catalog versus the frequency in searching was checked and Pearson’s correlation coefficient was calculated. The correlation was reasonably high at 0.74. Since the total number of terms and frequencies was much larger in the catalog, a plot of the rank of the terms in the catalog was plotted against the rank of the term in searching.
 This provided a very scattered plot with less clustering at the origin as in the original plot of frequencies. The Spearman rank correlation coefficient was moderate at 0.58. Some studies have suggested that removing high frequency and very low frequency terms from the search vocabulary will improve retrieval performance. This data shows that many general users actually use these terms in searching.
 Currently a sample of search words are being analyzed for factors which affect the correlation, such as errors in both the catalog and searching, the effect of truncations, and the effect of stemming (which was done on both the catalog vocabulary and the search terms).

Anti Diabetic Activity of Methanolic and Chloroform Extracts of Solanum seaforthianum In Alloxan Induced Diabetes Rats

Diabetes mellitus is a syndrome characterized by elevated glucose levels, polyurea, polydipsia and weakness due to insufficient entry of available glucose into the cells of the body. There are many allopathic drugs available to manage diabetes such as Sulfonylureas, biguanides, gliptins etc., but associated with hypoglycemia, sweating, dizziness, confusion, hunger, weight gain on long term usage and tolerance will be developed which are further treated using multiple drugs. According to our ancient system of medicine there are many medicinal plants available to treat diabetes with the same potency of allopathic drugs. Natural products are considered to be an effective alternative for the treatment and management of diabetes, because of higher efficacy which initiated the present study of anti diabetic activity of Solanum seaforthianum in an alloxan induced diabetes male albino rat. Diabetes was successfully induced with the help of alloxan at a dose of 120 mg/kg body weight and the animals which are possessing the glucose levels more than 250 mg/dL included in the study. Diabetic induced rats were treated with methanolic and chloroform extracts (200 and 400 mg/kg/kg body weight) of Solanum seaforthianum for 10 days. The collected blood samples on 1st, 4th, 7th, and 10th day were used to determine serum biochemical parameters such as cholesterol, triglycerides, low-density lipoprotein (LDL), high-density lipoprotein (HDL) cholesterol, urea, creatinine and total protein. Results: The treatment with extracts of Solanum seaforthianum significantly reduced the elevated blood glucose levels and reversed other altered parameters of Cholesterol, Triglycerides, HDL, LDL, Urea, Creatinine and Total Protein. Among the two extracts of Solanum seaforthianum chloroform extract has shown comparatively significant (p<0.001) anti diabetic activity in alloxan induced diabetes in albino rats.
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Термин различие в первых славянских грамматиках: проблемы сигнификата и денотата

The article is devoted to the analysis of the term razlichiye functioning in the first Slavic grammars. The research is based on the data contained in the works of Laurentiy Zizaniy and Meletius Smotrytsky, as well as in some later grammatical descriptions. On the basis of etymological, motivational and orienting analyzes, the ratio of denotative and significative components in the structure of the term, which in the first native grammars functioned as razlichiye, was identified. The review of theoretical research papers on the issue is introduced. The variability of the term usage resulting from the studied exponent signification and denotation ambiguity has been revealed. At the opening phase of the formation of grammatical terminology, reflected in the grammars of the Church Slavonic language in the 16 th – 17 th centuries the linguistic personality of grammarians, the cultural context of the era are proved to play an important role. The authors conclude that introducing the term razlichiye in the description of the Church Slavonic grammatical structure was the first step towards understanding the relational meaning of flexion as a morpheme. A comparative analysis of the term and its equivalents functioning in the grammars of ancient Greek, Latin, and Slavic languages has been performed. It was found that the interpretation of the medieval understanding of the term razlichiye as one of the parts of speech is recognized by the majority of modern researchers, but different assumptions are made about the significative and denotative correlation of the term (indicative-relative pronouns or articles). It is assumed that the signification of the term razlichiye in its modern interpretation can be explained as follows: it is a rudimentary inflectional category of syncretic (part-of-speech-and-affixal) nature, embodied in the forms of pronouns i, ja, e. The denotation of the term razlichiye is a transitional phenomenon between the realities corresponding to a definite article, an indicative-relative pronoun and an inflection.

MANAGEMENT OF TENNIS ELBOW BY VIDDAGNIKARMA: A CASE STUDY

Agnikarma is one of the Para surgical procedures in Ayurveda. It gives instant and long-lasting results. Agnikarma is indicated in Vata and Kapha's diseases and some painful conditions that involve the musculoskeletal system that comprises Sandhi, Asthi, Sira and Snayus. Tennis elbow or Lateral epicondylitis is a painful disease that causes restricted forearm movements. Only symptomatic treatments are available to date, which comprises Analgesics, Anti-inflammatory drugs, Physiotherapy, steroid injections, exercise etc. But none of them has satisfactory results. And causes some adverse effects by long term usage of these Analgesics and Anti-inflammatory drugs. In Ayurveda, Tennis elbow can correlate with Snayugatavata based on the symptoms. Agnikarma is indicated in this condition as told by Acharya Sushruta. Different Acharyas Suchi explained various Dahanopakaranas is one among them, which Acharya Chakra Datta. In this study, Tennis elbow was treated by Agnikarma using needles and electro-cautery along with Triphala Guggulu orally for seven days. It gives considerable relief from pain and movement of the elbow joint.

Ocular morbidity in patients on long-term selective serotonin reuptake inhibitors (SSRIs)

: To assess ocular morbidity in patients on long time anti-psychotic medication- SSRI.: Cross- sectional observational study was conducted on 96 patients on anti- psychotic medication (SSRI) who attended the OPD in Department of Ophthalmology and Psychiatry, from July 2019 to July 2021. : Of 96 patients, 71(73.9%) patients had ocular morbidity. Most common ocular morbidities were dry eye 62 (87.3%) followed by, reduced corneal sensitivity 3(4.2%), cataract 3 (4.2%), glaucoma 2(2.8%), ischemic optic neuropathy 1 (1.4%). Dry eye was the most common ocular morbidity seen. SSRIs on long term usage have significant ocular side effects, which should be kept in mind by both Ophthalmologists and Psychiatrics in their clinical practise.

Psychiatry on Twitter: Content Analysis of the Use of Psychiatric Terms in French.

BackgroundWith the advent of digital technology and specifically user-generated contents in social media, new ways emerged for studying possible stigma of people in relation with mental health. Several pieces of work studied the discourse conveyed about psychiatric pathologies on Twitter considering mostly tweets in English and a limited number of psychiatric disorders terms. This paper proposes the first study to analyze the use of a wide range of psychiatric terms in tweets in French.ObjectiveOur aim is to study how generic, nosographic, and therapeutic psychiatric terms are used on Twitter in French. More specifically, our study has 3 complementary goals: (1) to analyze the types of psychiatric word use (medical, misuse, or irrelevant), (2) to analyze the polarity conveyed in the tweets that use these terms (positive, negative, or neural), and (3) to compare the frequency of these terms to those observed in related work (mainly in English).MethodsOur study was conducted on a corpus of tweets in French posted from January 1, 2016, to December 31, 2018, and collected using dedicated keywords. The corpus was manually annotated by clinical psychiatrists following a multilayer annotation scheme that includes the type of word use and the opinion orientation of the tweet. A qualitative analysis was performed to measure the reliability of the produced manual annotation, and then a quantitative analysis was performed considering mainly term frequency in each layer and exploring the interactions between them.ResultsOne of the first results is a resource as an annotated dataset. The initial dataset is composed of 22,579 tweets in French containing at least one of the selected psychiatric terms. From this set, experts in psychiatry randomly annotated 3040 tweets that corresponded to the resource resulting from our work. The second result is the analysis of the annotations showing that terms are misused in 45.33% (1378/3040) of the tweets and that their associated polarity is negative in 86.21% (1188/1378) of the cases. When considering the 3 types of term use, 52.14% (1585/3040) of the tweets are associated with a negative polarity. Misused terms related to psychotic disorders (721/1300, 55.46%) were more frequent to those related to depression (15/280, 5.4%).ConclusionsSome psychiatric terms are misused in the corpora we studied, which is consistent with the results reported in related work in other languages. Thanks to the great diversity of studied terms, this work highlighted a disparity in the representations and ways of using psychiatric terms. Moreover, our study is important to help psychiatrists to be aware of the term use in new communication media such as social networks that are widely used. This study has the huge advantage to be reproducible thanks to the framework and guidelines we produced so that the study could be renewed in order to analyze the evolution of term usage. While the newly build dataset is a valuable resource for other analytical studies, it could also serve to train machine learning algorithms to automatically identify stigma in social media.

Quantifying the dynamics of nearly 100 years of dominance hierarchy research.

Dominance hierarchies have been studied for almost 100 years. The science of science approach used here provides high-level insight into how the dynamics of dominance hierarchy research have shifted over this long timescale. To summarize these patterns, I extracted publication metadata using a Google Scholar search for the phrase 'dominance hierarchy', resulting in over 26 000 publications. I used text mining approaches to assess patterns in three areas: (1) general patterns in publication frequency and rate, (2) dynamics of term usage and (3) term co-occurrence in publications across the history of the field. While the overall number of publications per decade continues to rise, the percent growth rate has fallen in recent years, demonstrating that although there is sustained interest in dominance hierarchies, the field is no longer experiencing the explosive growth it showed in earlier decades. Results from title term co-occurrence networks and community structure show that the different subfields of dominance hierarchy research were most strongly separated early in the field's history while modern research shows more evidence for cohesion and a lack of distinct term community boundaries. These methods provide a general view of the history of research on dominance hierarchies and can be applied to other fields or search terms to gain broad synthetic insight into patterns of interest, especially in fields with large bodies of literature. This article is part of the theme issue 'The centennial of the pecking order: current state and future prospects for the study of dominance hierarchies'.