Tentative Findings Research Articles

HabitWalk: A micro-randomized trial to understand and promote habit formation in physical activity.

Habit is a key psychological determinant for physical activity behavior change and maintenance. This study aims to deepen the understanding of habit formation in physical activity and identify promotion strategies. We examined the habit formation trajectory and its relationships with cue-behavior repetition (a cue-triggered 15-minute brisk walk) and unconditional physical activity (daily steps). We also tested whether the behavior change techniques (BCTs) 'commitment' and 'prompts and cues' promote habit, cue-behavior repetition, and daily steps within persons. This micro-randomized trial included a 7-day preparatory and a 105-day experimental phase delivered via the HabitWalk app. Participants (N = 24) had a 50% probability of receiving each BCT daily, leading to four conditions. Habit strength was assessed daily using the Self-Report Behavioral Automaticity Index, while cue-behavior repetition and steps were measured via an activity tracker. Person-specific growth functions indicated that habit strength trajectories were highly idiosyncratic. Multilevel models indicated a positive effect of cue-behavior repetition on habit strength, but not vice versa. The effect of habit strength on daily steps varied by the operationalization of cue-behavior repetition. Tentative findings suggest that commitment and prompts and cues are effective habit-promotion strategies when delivered together.

Making sense of big questions that require multiple subjects: preliminary theorisation of an integrative philosophy of knowledge and empirical indications of a lack of subject connection within school curricula

AbstractThis paper provides theorisation about a novel concept for education: an integrative philosophy of knowledge (IPK). This is proposed for school curricula to relate multiple subjects to big questions of personal and existential importance. Critical contemporary issues such as climate change education require multiple subject contributions but there is little clarity in the English education guidance on this drawing together, beyond the encouragement to do so in priority areas. Leading British thinkers have engaged the idea of the unity of knowledge, not without difficulty and criticism. The paper identifies reasons for a practical approach to consilience in school curricula. In addition to preliminary theorisation, in methodological ‘harmony’, this paper adds tentative empirical findings from a related research project that provides quantitative indications that such multi-subject connection is likely not happening. The findings are not definitive, but the perceptions of three groups of beginning and experienced teachers (secondary Religious Education (RE), secondary science and primary teachers) indicate that school curricula do not reflect an integrative approach to climate change education, and sex and relationships education, despite policy priority. A significant national survey could not detect many signs of connection. The paper speculates that RE could have a key epistemic role for the curriculum as a whole in this regard.

Flexicurity and employment inflows in the EU28 countries: a panel data analysis

PurposeThis paper examines the relationship between flexicurity and employment inflows in the EU28 countries over the 2007–2019 period. Flexicurity is defined as the mix of flexible contractual arrangements, social security systems, active labor market policies and lifelong learning strategies.Design/methodology/approachUsing two-way fixed effects two-stage least squares, we estimate the employment inflows as a function of an equal-weighted flexicurity composite indicator and other labor market, economic and business environment characteristics. To ensure the robustness of results, in additional specifications, we test the sensitivity of the flexicurity’s coefficient to: (1) the change of instruments; (2) the removal of different non-core variables and (3) the consideration of recessionary periods European regions. In addition, we estimate regressions with separate flexicurity components and with differently constructed flexicurity indices.FindingsIn all the estimations, increased flexicurity efforts are positively related to employment inflows. Increased flexicurity efforts benefit Eastern European countries more than the Northern and Anglo-Saxon groups. Not only a synergistic policy action that uses an equal combination of the four pillars of flexicurity has a positive impact on the employment inflow rate. Strategies that give more weight to the formation of skills seem to favor the labor market reinsertion most.Originality/valueTo our knowledge, this is the first comprehensive study in the flexicurity–employment inflows literature since it: (1) follows all the European Union countries over more than a decade; (2) brings some tentative findings on the socio-cultural moderation of flexicurity’s impact on employment inflows and (3) explores different country-level flexicurity indices.

Retrospective screening of new psychoactive substances (NPS) in post mortem samples from 2014 to 2021

Systematic retrospective processing of previously analysed biological samples has been proven to be a valuable tool in the search for new drugs (e.g. new psychoactive substances (NPS)) and for quality assessment in clinical and forensic toxicology. In a previous study, we developed a strategy for retrospective data-analysis using a personalized library of synthetic cannabinoids, designer benzodiazepines and synthetic opioids obtained from the crowdsourced database HighResNPS (https://highresnps.com). In this study, the same strategy was employed for the compounds within the groups of NPS that were not previously included such as synthetic cathinones, phenethylamines, aminoindanes, arylalkylamines, piperazine derivates, piperidines, pyrrolidines, indolalkylamines and arylcyclohexylamines. Synthetic opioids and designer benzodiazepines, which were not part of the previous study, were also included. To enhance the effectiveness of the retrospective analysis, a predicted retention time was included for all entries. Data files from the analysis of 2186 forensic post mortem samples with an Agilent Technologies 6540 ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS) performed in the laboratory from January 2014 to December 2021 were retrospectively processed with the up-to-date library. Tentative findings were classified in two groups: The findings where MS/MS data was acquired for library match (category 1) and the less certain findings where such data lacked (category 2). Five compounds of category 1 (three synthetic cathinones and two indolalkylamines) were identified in 12 samples. Only one of the findings, 4-MEAPP (4-methyl-α-ethylaminopentiophenone), was deemed plausible after reviewing case information. As many as 501 presumably positive category 2 findings were detected. Using the predicted retention time as an additional criterion the number was significantly reduced but still too high for a manual review. This work has demonstrated that the strategy developed in the previous study can be applied to other NPS groups. However, it is important to note the limitations such a method may have in detecting compounds at very low concentrations.

Will the children have faith in the post-pandemic era? Investigating models of children’s faith formation in a world changed by pandemic experiences

ABSTRACT In a world significantly marked by the COVID-19 pandemic, we examine the modes of contemporary children’s faith formation and ask why these have not altered in light of so much societal change. What is the role and function of faith communities in nurturing a child’s faith in contemporary times? Almost fifty years ago, John Westerhoff first asked the question: ‘Will our children have faith?’ critiquing processes of children’s faith formation. This paper seeks to examine this same question, now in the context of widespread pandemic prompted self-evaluation of religious perspectives and practices. This study examines parental and church perspectives on modern-day children’s Christian faith formation, investigating the effectiveness of established paradigms. The tentative findings reveal significant disconnections regarding perceptions, expectations and roles of key players and an urgent need for revising of the established and dominant methods of the global church in their efforts to effectively nurture the faith of younger generations.

A Single-Center Analysis of How HLA Mismatch and Donor-Specific Antibodies Affect Short-Term Outcome After Lung Transplantation: A Pilot Study Before a Country-Wide Histocompatibility Study in Japan

Analyzing HLA polymorphism in lung transplantation (LTx) is important, given its impact on LTx recipient survival and graft function. Accordingly, we conducted a retrospective study to examine the influence of HLA mismatch and donor-specific antibodies (DSA) on short-term outcomes and early-phase post-LTx complications. HLA antigen or eplet mismatch in LTx patients at Tohoku University Hospital from 2018 to 2023 was determined, and DSA was measured on admission for surgery to identify preformed DSA and at weeks 4 to 12 post-LTx for de novo DSA, respectively. The participants were 45 LTx recipients, HLA-A/B/DR antigen mismatch (5-6 of 6) being identified in 57%, HLA-A/B/Cw/DR/DQ mismatch (8-10 of 10) in 57%, and HLA eplet mismatch (>61) in 46%. The prevalence of preformed DSA was 24%, and persistence (uncleared) was 16%. The incidence of de novo DSA was 16% after LTx. During the study,16 recipients experienced grade 3 primary graft dysfunction (PGD), 8 developed acute rejection, and 5 died. No HLA-related variables were significantly associated with post-LTx mortality and were not risk factors for high-grade PGD or acute rejection. Despite limitations in sample size, resulting in tentative findings, the study serves as a crucial pilot study for an ongoing multicenter prospective trial in Japan.

Developing interfaith interventions to address hesitancy towards COVID-19 vaccination: protocol for a focus group-based, exploratory qualitative study

IntroductionThe COVID-19 pandemic demonstrated how vaccine hesitancy impacts are translated nationally and internationally. A predictor of vaccine hesitancy is religious beliefs (eg, the body being sacred and should be healed...

Reflection on action by activation workers as professional learning strategy

ABSTRACT In this article, social work theory on reflective practice is used to explore the potential value of reflection on action for professional learning by activation workers who support people receiving welfare benefits to find work. The article focuses on the role of reflection on action in professional learning concerning three challenges which activation workers face: dealing with normative dilemmas, translating formal and informal knowledge into decision-making and dealing with power relations. The article presents tentative findings stemming from qualitative research on Dutch activation workers participating in reflection on action. Participants report multiple learning outcomes concerning these challenges. The theoretical and empirical exploration suggests that reflection on action can support learning by activation workers to better deal with professional challenges inherent to their work. However, these empirical findings are preliminary and based on a specific context. Further exploration by both scholars and practitioners is therefore suggested, in which the social work profession has a lot to offer.

Exploring the relationship between willingness to communicate and cultural capital in a language learning context - a qualitative investigation

The qualitative study is intended to determine if there is a potential relationship between willingness to communicate and cultural capital in young learners of English and whether it may be possible to assess levels of cultural capital and cultural participation in a quantitative fashion, which would then open the way for a broader range of studies that would allow for regressive analysis of the relationship between cultural capital and a broad range of individual differences to determine the extent to which this may be a key factor in language acquisition and learning. The qualitative investigation was conducted on five participants who were willing to give interviews during a language camp in the UK in the summer of 2022. All five of the participants scored highly on a WTC assessment scale and also showed confidence in communicating in a non-classroom environment. The tentative findings of the study would appear to indicate that there is a firm basis for further research on a quantitative scale in order to validate the basic hypothesis.

Distributed Resource Centre: A Soft Infrastructure for Neighbourhood Creativity

This article presents the Distributed Resource Centre as a soft, low-cost, generative, and fun decentralised infrastructure for neighbourhood creativity. The article defines the concept (as flow vs stock), outlines some broad benefits (increased interfaces and resource availability, fostering of creative capability, and cost reductions), discusses the pilot and development projects which were involved in the development of the concept, and presents tentative findings for further exploration and discussion (making friends, porous, asynchronous and uncertain activity, neighbourhood = resource centre, berm = interface, multidimensional art centre). The submission ends with a coda and an invitation.

The ‘Clinical Humanities & Wellbeing programme’- sustainable healthcare education for an era of uncertainty

This article presents a case study where integration of arts and humanities into a clinical programme is being implemented at scale, as core mandatory learning for all students within a UK dental, undergraduate context. The cross-disciplinary programme described, that integrates the Humanities with Clinical Sciences, is a longitudinal professional identity formation curriculum for sustainable oral healthcare which aligns with the UK dental regulator’s proposals for a ‘safe practitioner’ framework for new graduates. The Clinical Humanities & Wellbeing modules embrace the emotional and attitudinal aspects of learning and educate clinical students for the practical wisdom (phronesis) required to deliver 21st century oral healthcare in an era of uncertainty. The overarching aim of the curriculum and its accompanying assessment is to promote critical reflection, student insight and development of integrity, reflexivity, and responsibility. Enabling the subjectification of professional identity formation in this cross-disciplinary way aims to develop students as ‘safe practitioners’, with increased professional autonomy, responsible for their own actions, and who are better equipped for the uncertainties and phronesis of clinical practice. At present, the programme is being evaluated, employing illuminative evaluation methodology and we present some tentative initial findings. The authors believe that this unique approach and signature pedagogy is, with careful curation, transferrable to other health professions’ contexts.

Familial Risk for Schizophrenia vs Bipolar Disorder and Task-Based Neural Activation: A functional Magnetic Resonance Imaging Meta-Analysis.

Individuals at familial risk for developing schizophrenia (FRSZ) or bipolar disorder (FRBD) have shared and unique genetic risks. Few studies have compared neural activation between these two groups. Therefore, the present meta-analysis investigated functional brain similarities and differences between FRSZ and FRBD individuals. A systematic literature review was conducted of articles that compared FRSZ or FRBD individuals to healthy controls (31 FRSZ and 22 FRBD). Seed-based d mapping was used to conduct the meta-analysis. Analyses included comparisons of FRSZ to controls, FRBD to controls, and both relative groups to each other. Using a highly conservative family-wise error rate correction, there were no significant findings. Using a less conservative threshold, FRSZ compared to controls had lower activation in the left precuneus (Puncorrected = .02) across all studies and in the left middle frontal gyrus (Puncorrected = .03) in nonsocial cognition studies. FRBD compared to controls had lower activation in the left superior parietal gyrus (Puncorrected = .03) and right angular gyrus (Puncorrected = .03) in nonsocial cognition studies, and higher activation in the left superior frontal gyrus (Puncorrected = .01) in social tasks. Differences between FRSZ and FRBD were not significant. There were few robust differences between FRSZ or FRBD compared to controls. This suggests only weak support for neural activation differences between individuals at genetic risk for schizophrenia or bipolar disorder and controls. The tentative findings observed were in different brain regions for FRSZ and FRBD, with no strong evidence for shared effects between schizophrenia and bipolar genetic risk on neural activation.

Discussion of off-target and tentative genomic findings may sometimes be necessary to allow evaluation of their clinical significance

We discuss a case where clinical genomic investigation of muscle weakness unexpectedly found a genetic variant that might (or might not) predispose to kidney cancer. We argue that despite its...

Managers perception of hospital employees’ effort-reward imbalance

ObjectiveHospitals are frequently associated with poor working conditions that can lead to work stress and increase the risk for reduced employee well-being. Managers can shape and improve working conditions and thereby, the health of their teams. Thus, as a prerequisite, managers need to be aware of their employees’ stress levels. This study had two objectives: At first, it aimed to test the criterion validity of the Effort-Reward Imbalance (ERI) questionnaire measuring psychosocial workload in hospital employees. Secondly, mean scales of the ERI questionnaire filled in by employees were compared with mean scales of an adapted ERI questionnaire, in which managers assessed working conditions of their employees.MethodsManagers (n = 141) from three hospitals located in Germany assessed working conditions of their employees with an adapted external, other-oriented questionnaire. Employees (n = 197) of the mentioned hospitals completed the short version of the ERI questionnaire to assess their working conditions. Confirmatory factor analyses (CFA) were applied to test factorial validity, using the ERI scales for the two study groups. Criterion validity was assessed with multiple linear regression analysis of associations between ERI scales and well-being among employees.ResultsThe questionnaires demonstrated acceptable psychometric properties in terms of internal consistency of scales, although some indices of model fit resulting from CFA were of borderline significance. Concerning the first objective, effort, reward, and the ratio of effort-reward imbalance were significantly associated with well-being of employees. With regard to the second objective, first tentative findings showed that managers’ ratings of their employees’ effort at work was quite accurate, whereas their reward was overestimated.ConclusionsWith its documented criterion validity the ERI questionnaire can be used as a screening tool of workload among hospital employees. Moreover, in the context of work-related health promotion, managers’ perceptions of their employees’ workload deserve increased attention as first findings point to some discrepancies between their perceptions and those provided by employees.

Media convergence for US–China competition? Comparative case studies of China Media Group and the US Agency for Global Media

The present study provides a comparative analysis of the media convergence of China Media Group and US Agency for Global Media to illustrate the increasing US–China rivalry in international communication. It yields the following tentative findings: Both have been undergoing rigorous development at the technological and operational levels of convergence to enhance international communication; both are made to show more explicit loyalty to its official ideology, and both have become more monolithic via convergence; both have integrated their broadcasting services for an increasingly integrated market of information and news; both seem to be weaponizing itself against each other to fuel rivalry in international communication between the two nations rather than deepening mutual understanding and cooperation for mutual good and global good. The two case studies reveal that media convergence has not been able to liberate journalism from nationalistic constraints and transform it into an instrument to spawn new ideas and disseminate high-quality information and news for global public good.

Beyond taxonomies: Vagrantly “inhabiting” the modernist classroom

AbstractThis article takes the current transnational turn in modernist studies as entry point to probe how that plays out in the classroom in non‐Western locations that are often also the “locales” of that disciplinary shift. I propose a waylaying of the energies of dispersion and diffusion that currently animate the modernist field to decolonize the modernist classroom through a parallel vagrancy, but one focused on recovering the local from these compelling taxonomic shifts. It is quite easy to be sucked under by the adrenaline rush of these expansions of new modernist studies that mirror modernism's own self–mythologies. To resist that, we need to be vagrants inside the classroom, to bring into it the choice pickings from our wider reading and research. Our fealty to the modernist archive and the professional competence incumbent on us notwithstanding, our ability to bring tentative new findings from our own research and readings, can potentially dynamize our teaching spaces, as also our commitment to a more decenterd approach. Ready embraces of belatedly discovered writers into the modernist corpus might make our taxonomies look suitably plural and fashionable but subsume the writers' own demonstrated recalcitrance to those taxonomies. Teaching modernism as a core course with a fixed, prescribed, syllabi comprising largely of the Anglo‐American presences such as Virginia Woolf and Joseph Conrad has in some ways released the itinerant in me. Through carefully culled examples from my own teaching of the modernist canon, I argue that a genuine opening of modernist studies within the classroom can come from a tempering of the ‘professional’ by itinerant interludes.

Magnetic Resonance Neuroimaging of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a lifelong, relapsing, chronic inflammatory disease of the digestive tract that can be brought on by a number of different etiologies. Studies have shown that patients with IBD also have nervous system involvement in addition to well-known extra-intestinal symptoms like arthritis and iritis, and researchers believe that neurological lesions in patients with IBD may be an important extra-intestinal manifestation. Currently, tentative findings from studies employing magnetic resonance imaging to study the brain structure and function of patients with IBD have been made.

Pilot-RCT Finds No Evidence for Modulation of Neuronal Networks of Auditory Hallucinations by Transcranial Direct Current Stimulation.

Background: Transcranial direct current stimulation (tDCS) is used as treatment for auditory verbal hallucinations (AVH). The theory behind the treatment is that tDCS increases activity in prefrontal cognitive control areas, which are assumed to be hypoactive, and simultaneously decreases activity in temporal speech perception areas, which are assumed to be hyperactive during AVH. We tested this hypofrontal/hypertemporal reversal theory by investigating anatomical, neurotransmitter, brain activity, and network connectivity changes over the course of tDCS treatment. Methods: A double-blind, randomized controlled trial was conducted with 21 patients receiving either sham or real tDCS treatment (2 mA) twice daily for 5 days. The anode was placed over the left dorsolateral prefrontal cortex (DLPFC) and the cathode over the left temporo-parietal cortex (TPC). Multimodal neuroimaging as well as clinical and neurocognitive functioning assessment were performed before, immediately after, and three months after treatment. Results: We found a small reduction in AVH severity in the real tDCS group, but no corresponding neuroimaging changes in either DLPFCD or TPC. Limitations: The study has a small sample size. Conclusion: The results suggest that the currently leading theory behind tDCS treatment of AVH may need to be revised, if confirmed by studies with larger N. Tentative findings point to the involvement of Broca’s area as a critical structure for tDCS treatment.

Patterns in Second Language Utterance Fluency: An Exploratory Meta-analysis of Correlational Research

This paper describes an exploratory meta-analysis of correlations between second language (L2) utterance fluency (UF) phenomena. UF refers to the temporal, pausing, and repair features of speech. Correlations between 24 pairings of UF measures were meta-analyzed, encompassing a total of 179 effect sizes from 31 primary studies. Results indicate that most of the UF measure pairings display weak to moderate correlations in the expected direction. On the other hand, there were significant correlations in the unexpected direction between several breakdown phenomena, suggesting a trade-off effect may have occurred. Thirdly, some measure pairings displayed no significant correlation in either direction, suggesting they may function independently of each other in L2 speech. Finally, suggestions are made as to how these tentative findings can be explored in future research.

Simulation of Heat Flow in a Synthetic Watershed: Lags and Dampening across Multiple Pathways under a Climate-Forcing Scenario

Although there is widespread agreement that future climates tend toward warming, the response of aquatic ecosystems to that warming is not well understood. This work, a continuation of companion research, explores the role of distinct watershed pathways in lagging and dampening climate-change signals. It subjects a synthetic flow and transport model to a 30-year warming signal based on climate projections, quantifying the heat breakthrough on a monthly time step along connected pathways. The system corresponds to a temperate watershed roughly 27 km on a side and consists of (a) land-surface processes of overland flow, (b) infiltration through an unsaturated zone (UZ) above an unconfined sandy aquifer overlying impermeable bedrock, and (c) groundwater flow along shallow and deep pathlines that converge as discharge to a surface-water network. Numerical simulations show that about 40% of the warming applied to watershed infiltration arrives at the water table and that the UZ stores a large fraction of the upward-trending heat signal. Additionally, once groundwater reaches the surface-water network after traveling through the saturated zone, only about 10% of the original warm-up signal is returned to streams by discharge. However, increases in the simulated streamflow temperatures are of similar magnitude to increases at the water table, due to the addition of heat by storm runoff, which bypasses UZ and groundwater storage and counteracts subsurface dampening. The synthetic modeling method and tentative findings reported here provide a potential workflow for real-world applications of climate-change modeling at the full watershed scale.