The 7A52 aluminum alloy of 10mm thickness was welded by laser-MIG hybrid welding. The microstructures and properties of the welded joints were studied. The results show that: The morphology of the weld section is “glass shape”, and the “cup body area” of the top of the weld is formed by the arc thermal melting base material, with typical MIG welding characteristics. And the “cup foot area” of the bottom weld is produced by the keyhole effect and has the characteristics of laser deep fusion welding. The Zn and Mg elements have different degrees of evaporation and loss in the MIG welding zone and laser welding zone. The hardness from the center of the weld to both sides base metal is a u-shaped distribution. The average tensile strength of welded joints reached 304.7MPa, which is 74.3% of the base material.