This paper presents a general overview of nuclear data evaluation and its applications as developed at NRG, Petten. Based on concepts such as robustness, reproducibility and automation, modern calculation tools are exploited to produce original nuclear data libraries that meet the current demands on quality and completeness. This requires a system which comprises differential measurements, theory development, nuclear model codes, resonance analysis, evaluation, ENDF formatting, data processing and integral validation in one integrated approach. Software, built around the TALYS code, will be presented in which all these essential nuclear data components are seamlessly integrated. Besides the quality of the basic data and its extensive format testing, a second goal lies in the diversity of processing for different type of users. The implications of this scheme are unprecedented. The most important are:1. Complete ENDF-6 nuclear data files, in the form of the TENDL library, including covariance matrices, for many isotopes, particles, energies, reaction channels and derived quantities. All isotopic data files are mutually consistent and are supposed to rival those of the major world libraries.2. More exact uncertainty propagation from basic nuclear physics to applied (reactor) calculations based on a Monte Carlo approach: “Total” Monte Carlo (TMC), using random nuclear data libraries.3. Automatic optimization in the form of systematic feedback from integral measurements back to the basic data. This method of work also opens a new way of approaching the analysis of nuclear applications, with consequences in both applied nuclear physics and safety of nuclear installations, and several examples are given here. This applied experience and feedback is integrated in a final step to improve the quality of the nuclear data, to change the users vision and finally to orchestrate their integration into simulation codes.