Relative Tendency Research Articles

Stabilization of ultrathin nanowires by self-assembly into bundles

The relative tendency of freely dispersed and bundled gold nanowires to break up along their length by the Rayleigh–Plateau instability is investigated both experimentally and theoretically. Small angle X-ray scattering, in combination with transmission electron microscopy, reveal that the bundling of nanowires can enhance their stability. The experimental observation is rationalized by a linear perturbation analysis of a representative unit cell of bundled wires. A stability map is constructed for a bundle of nanowires to display the sensitivity of the Rayleigh–Plateau instability to the number and size of contacts with nearest neighbors per nanowire, and to the ratio of interfacial energy to surface energy. Stabilisation is enhanced by allowing the bundle of wires to sinter freely: a criterion for this kinetically-based stabilisation is given in terms of the ratio of pinch-off time for the instability to the sintering time to form the necks between nanowires.

Salting-Out-Assisted Liquid–Liquid Extraction for Nicotine from Its Aqueous Solutions

The complete effectiveness of various inorganic salts (NaCl, KCl, NaBr, KBr, Na2CO3, and Na2SO4) to form two-phase systems was systematically evaluated for separating nicotine from its aqueous solutions. The binodal curve and tie lines for nicotine + salt + water ternary systems were experimentally determined at 298.15 K and atmospheric pressure. The salting-out effectiveness was accounted for by phase diagrams, as well as partition coefficients and recovery percentages of nicotine. The binodal curves obtained experimentally were successfully fitted to the Merchuk model, and the reliability of tie-line data was evaluated using the Othmer–Tobias and Bancroft equations. The results clearly show that all investigated salts, as salting-out media, cause the expansion of the two-phase region and have high partition yield for the separation of nicotine from its aqueous solutions. It is also observed that both cations and anions present an influence on the liquid–liquid equilibrium. The relative tendency of anions to form two-phase systems, CO32– > SO42– > Cl– > Br–, follows the position of anions in the Hofmeister series. Due to the stronger interaction of Na+ with the nicotine nitrogen than K+, the effectiveness order of cations (K+ > Na+) follows the opposite trend with the Hofmeister series. Furthermore, the order Na2CO3 > Na2SO4 > KCl > NaCl > KBr > NaBr for the effective excluded volume (EEV) of different salts is consistent with the size order of the heterogeneous region. Thus, EEV can be used as a predictive tool for the biphase-forming ability of salts. The partition coefficients and recovery percentages of nicotine are found to increase with the increase of temperature and pH. The calculated entropy of the cloud point indicates that the high positive entropy is the driving force for the two-phase formation.

Resisting Whilst Complying? A Case Study of a Power Struggle in a Business School

Business school faculty are frequently faced with management practices they find objectionable. Reactions vary, but compliance and hidden resistance are common responses. In this paper, we seek to understand compliance and hidden resistance as responses to objectionable management practices in business schools. To explore this problem, we present a case study of a business school where a new dean brought about aggressive and abrupt managerialist changes toward which faculty were broadly hostile. Faculty eventually failed to resist these changes and ended up resorting to exits and workplace disengagement whilst complying with management expectations regarding work outputs. To make sense of compliance and hidden resistance as responses to ob-jectionable management practices in business schools, we propose the following concepts: merce-nary mentality and resipliance (a combination of expressing resistance attitudes to peers – and to self – and complying with management demands for work outputs). The presence of a mercenary mentality and the related tendency to resipliance – which we argue are common in business schools – undermines the capacity for resistance against objectionable management practices at the workplace, reminding us that resistance is fragile and elusive.

The determinants of group membership in organized crime in the UK: A network study

ABSTRACT In this paper, we explore the determinants of co-membership in organised crime groups in a British police force. We find that co-membership of OCGs is higher among individuals who share the same ethnicity and nationality; who have committed acts of violence; and who perpetrate the vast majority of their crimes in the same area. We also find a homophily tendency in relation to age and gender, and that task specialisation within groups is driven by the type of activity. We interpret some results as conforming to the argument that recruitment from a small area and similar ethnic/national background increases cooperation and reduces the likelihood of opportunistic behaviour in a context of rather effective policing. Our findings do not conform to the suggestive image of OC members as ‘urban marauders’ and OCGs as large and powerful multinationals. OCGs tend to be small, localised and formed by people with the same background.

Towards public competition in a pluralist polarized country: Professionals’ newsroom discourses on autonomy, public statements and regulation

This study explores the interaction between journalists’ discourses on values and practices and the regulations affecting them in the shape of public statements, which are considered to be an influential variable in journalistic practice. However, the process of producing such statements requires further attention, in particular the role of newsroom discourses. The case of the Spanish public service broadcaster RTVE illustrates this tendency in relation to the regulations governing it and their impact on newsroom routines and newsmaking. Over the past fifteen years, RTVE has been subject to contradictory reforms, during which the discourses of TVE journalists have taken the shape of public statements issued by several professional associations calling for a reduction in RTVE’s traditional political dependence. Accordingly, the focus is placed here on the evolution of those discourses from 2006 to 2019, as to (1) the way in which they were transformed into public statements in persuasive campaigns with an influence on regulation, particularly as to the election of the executive board and chairperson of RTVE by public competition, and (2) the interaction and influence of core values such as professional independence and diversity on shaping newsroom discourses and public statements.

Relative geographic concentration of creative, other traded, and local industries using establishment data and Harvard's U.S. Cluster Mapping Benchmark Definitions

This paper examines the relative tendency of industries and industry clusters to be geographically concentrated. Creative industries defined as having distinct artistic creation and production-distribution components are examined. This extends previous observations that creative industries exhibit a relatively high degree of geographic concentration to examine whether two-sided market dynamics contribute to this concentration. Variance in the distribution of business establishments among U.S. metro areas for 978 industries is calculated using County Business Patterns data from the U.S. Census Bureau. The data is mapped to different clusters using Harvard University's U.S. Cluster Mapping Benchmark Definitions. The average variance of each cluster is calculated to measure relative concentration.•Richard Caves’ definition of creative industries is used to identify industries characterized by a two-sided structure.•Harvard University's U.S. Cluster Mapping Benchmark Definitions are used to map creative industries to specific industry codes and industry clusters.•These two methods are applied to U.S. County Business Patterns data to examine the relative geographic concentration of two-sided creative clusters.

GERMAN-BASED INTERNET LINGUISTICS: HISTORY REVIEW AND MODERN TRENDS

This article focuses on a new linguistic discipline called Internet linguistics, reveals historical aspects of its formation, and summarizes research strategies in modern linguistic studies in German-speaking countries. The article provides a brief overview of the main studies on Internet-linguistics by German-speaking researchers from the late 1980s to the present. Research analysis evaluates important terminological aspects: debates around key concepts and objects of study. With the invention of the Internet and rapid progress made in digital media, forms of social interaction were significantly impacted, along with related tendencies of development of the modern German language. The analysis highlights a contribution of German-speaking academic researchers to the debate on the possibility of distinguishing a special language of the Internet and language criticism on the Internet. The article presents the studies addressing the topic focus on linguistic innovations on the Internet and the pragmatic potential of the linguistic phenomena typical for the modern German language. The article briefly describes the research approaches to the problems of new media and new forms of communication in the digital world (SMS text messages, chat rooms, blogs, tweets, etc.), multimodal Internet phenomena (emoji, memes), standards and rules of online behavior (Netiquette). Contemporary studies forced a new viewpoint on some concepts from related disciplines such as “code-switching”, conceptual oralness and conceptual writing, proximity language and distance language. The necessary part of the article deals with the discursive and applied aspects of the Internet linguistics, such as creation of the Internet corpora, launching international projects, etc.

Components of Context: Respecifying the Role of Context in Migration Research

For a century, scholars have studied immigrant integration in a range of destinations. Yet, the precise role of context in shaping integration outcomes remains poorly understood. Drawing from an analysis of an original database of articles and books in migration studies, I argue that this knowledge gap may be due to two closely related tendencies in the scholarship. First, case selection has relied on criteria such as the immigrant population's size and growth rate that are not clearly connected to integration outcomes. Second, most scholars have studied either heavily urban contexts (with large immigrant populations) or very rural contexts (where the immigrant population is growing rapidly), while much less attention has been given to destinations in-between. To improve the understandings of the role of context in immigrant integration, migration scholars should endeavor to move past population criteria when selecting study sites and to study the full range of contexts where immigrants are settling. To contribute to these efforts, I propose a framework that does not rely on population or newness as criteria for case selection and that focuses, instead, on the components of context that existing research has shown matters for intergenerational mobility. I also introduce a typology of contexts based on possible combinations of four of these components and offer some initial hypotheses of how these context types might affect immigrant integration. The arguments presented here recenter the role of local context in migration studies and contribute to debates about where and how scholars should study context moving forward.

Evolution of verbal instruments of management communication in the context of the concept of diglossia

Methods. The results were obtained using a system of methods: method of logical analysis made it possible to build the logic of the study; structural analysis, grouping, decomposition and formalization made it possible to substantiate the sequence of stages in the implementation of the methodological approach to assessing the level of development of trade and economic relations; methods of statistical analysis were used to assess the dynamics of indicators of the influence of foreign markets; graphic method made it possible to visualize the results of the study. Results. The authors of the article substantiated practical recommendations regarding the implementation of the export potential in the trade and economic relations of Ukraine with the EU countries. A detailed description of the dynamics of the volume of exports and imports of goods in value terms between Ukraine and the EU was considered. To analyze the processes of activation of trade and economic relations in the aspect of the European integration processes of development of the Ukrainian state, the dynamics of the share of foreign trade turnover with the EU countries was studied. The dynamics of trade in services between Ukraine and the EU is analyzed. To calculate the degree of development of trade and economic relations of countries, the calculation of an integral index based on relative indicators is proposed. It is substantiated that this method makes it possible to classify the countries of the EU and Ukraine according to the degree of development of trade and economic relations. On the basis of the obtained results, a radar of the degree of development of trade and economic relations between the EU countries and Ukraine was built. The general tendencies of trade and economic relations of Ukraine with the EU countries are highlighted and it is determined that the foreign economic activity of Ukraine with the EU countries has a great potential for development. Based on the analysis, proposals were made to improve the export potential in Ukraine's trade and economic relations with the EU countries. Novelty. A set of measures is proposed to realize the export potential of Ukraine in trade and economic relations with the EU countries, in particular, a scientific and methodological approach is proposed for calculating the integral index of the development of trade and economic relations of countries, which allows classifying countries according to the degree of development; recommendations were given on the development of the export potential of Ukraine with the EU countries. Practical value lies in the possibility of using the developed methodological framework to assess the degree of development of trade and economic relations not only with European countries, but also with other countries of the world.

P063 Prevalence in the Use of Complementary/Alternative Medicine in Patients With Inflammatory Bowel Disease from Centro Médico Nacional 20 de Noviembre.

Frequently, existing therapies for inflammatory bowel disease (IBD) do not achieve complete remission of the disease and are commonly associated with adverse effects. Therefore, patients regularly turn to complementary or alternative medicine (CAM). International CAM use in IBD patients ranges from 21% to 60%. There are no reported statistics of CAM use in the Mexican population who suffer IBD. This study´s objective was to determine the prevalence and characterize the use of CAM in our IBD population. Observational, cross-sectional, retrospective study in patients diagnosed with IBD belonging to our Institution's IBD center. The results were analyzed with measures of relative frequency, central tendency, and dispersion. A total of 52 patients with IBD (78% ulcerative colitis and 22% Crohn's disease) were included, 38.5% were exposed to CAM. A total of 27% used it as an aid in their IBD treatment. The remaining 11.5% used it for other reasons. Patients exposed to CAM for IBD averaged 51 ± 19 years, 64% were female and 71% had at least an undergraduate degree. The most used CAMs were acupuncture (42.8%), herbal (35.7%) and homeopathy (35.7%). Half of the patients used concomitantly two or more modalities, and 91.6% of the patients knew their diagnosis at the time that CAM was being used. The median exposure time to CAM was 4.5 ± 40.7 months. The main reasons for the use of CAM in IBD patients was as a complementary therapy in 58.3%, as the perception of lack of improvement was present in 33.3% of patients. Twenty-five percent of patients used CAM after a healthcare professional recommended it. CAM was used in 83.2% of patients with conventional treatment (Mesalamine: 74.6%, Mesalamine + Azathioprine: 8.3%) and only 16.5% were on biological therapy. A total of 58.3% CAM users perceived improvement in their symptoms. Currently 25% still use some modality of CAM. No statistically significant differences were found in sociodemographic variables and clinical outcomes when comparing the IBD group exposed to CAM vs the unexposed group. Exposure to CAM for IBD treatment had a prevalence of 27%. The main CAM modalities for IBD patients were acupuncture, herbal, and homeopathy. No relationship was demonstrated between the use of CAM in IBD patients and their clinical outcomes.

Bayesian dynamic network actor models with application to South Korean COVID-19 patient movement data

Motivated by the ongoing COVID-19 pandemic, this article introduces Bayesian dynamic network actor models for the analysis of infected individuals’ movements in South Korea during the first three months of 2020. The relational event data modelling framework makes use of network statistics capturing the structure of movement events from and to several country’s municipalities. The fully probabilistic Bayesian approach allows to quantify the uncertainty associated to the relational tendencies explaining where and when movement events are established and where they are directed. The observed patient movements’ patterns at an early stage of the pandemic can provide interesting insights about the spread of the disease in the Asian country.

Play tendency and prosociality in early childhood

ABSTRACT This study examines preschool children's play tendency and their prosocial behavior. The screening method was used in the study, and it was carried out with a total of 319 four- to six-year-old children who attended state kindergartens. “Children's Playfulness Scale” and “Child Prosocialness Scale” were used as data collection tools. According to the results, no significant difference was found in the play tendency and prosocial behavior scores in relation with gender and parent's employment status. However, a significant difference was found in the play tendency and prosocial behavior scores in relation with age and family income. In terms of the number of siblings, while there was no significant difference in prosocial behavior scores, a significant difference was found in the play tendency. A significant positive relationship was found between the play tendency and prosocial behavior scores. The findings are discussed with regard to the relevant literature.

СУЧАСНІ ТЕНДЕНЦІЇ РОЗВИТКУ ПОДІЄВОГО ТУРИЗМУ НА ЗАКАРПАТТІ

Theoretical principles and history of study of eventful tourism, his classification, and also modern state of this sphere, are considered in the article. Progress of eventful tourism trends are analysed on Zakarpattia and it is set that during the last years there are positive tendencies in relation to their development, in particular: the specialized tour operators that offer corresponding tours and the new objects of eventful rest are opened appear. It is educed that Zakarpattia is extraordinarily rich in traditions and ethnic colour and has considerable advantages for development of eventful tourism, as here is considerable tourist-recreational potential. In villages and small towns Zakarpattia the most various and interesting festivals and holidays pass that, it is possible conditionally to divide into three groups-guilty, gastronomic and folklore. Lately large popularity was purchased by the tours of flowers on Zakarpattia. Eventful tourism is perspective on Zakarpattia, with inexhaustible resource potential, and the programs of festivals are saturated, original and interesting and profitable. They assist to socio-economic development of area, popularization of potential tourist resources among a population. Important pre-condition of organization of festival tourism is the timely informing and advertising of events, popularity to information about her and organization of her systematic realization. Most permanent festivals have own web-sites, on that there is information about realization and program of measures, tourist infrastructure, transport report. Forming of positive image of region and increase of amount of tourists is assisted by tourist-informative centers that accumulate information about tourist-recreational suggestions. Without regard to plenty of festivals international status is had only separate from them. Therefore, in order to attract the attention of tourists to Zakarpattia, it is expedient to create the government program of assistance and development of festival motion and distinguish the regional centers of festival tourism. Such regional centers can be cities that are selected on the principle of scale and the possibility of representation of an event. Such centers in the region can be Uzhgorod, Beregovo, Rakhiv, Mukachevo.

Exploring Locus-of-Hope: Relational Tendencies, Self-Esteem, Attachment, and Gender.

Background: As little research has been devoted to examining associations between the four locus-of-hope dimensions (internal, external—peer, external—family, and external—spiritual) and individual differences, the current study explores the correlations with individual-level individualist and collectivist relational tendencies, self-esteem, insecure attachment, and gender within a culturally diverse sample of university undergraduate students. Methods: questionnaires were completed by a culturally diverse sample of undergraduate students measuring locus-of-hope, individualist and collectivist relational tendencies, self-esteem, insecure attachment, and gender. Results: State and trait locus-of-hope were significantly correlated. Individualism showed positive correlations with internal and external—family locus-of-hope. Collectivism positively correlated with internal locus-of-hope and the three external locus-of-hope dimensions. Internal locus-of-hope was significantly predicted by self-esteem, relational self-esteem, individualism, and collectivism. External—spiritual locus-of-hope was not significantly predicted by the variables. External—family locus-of-hope was significantly predicted by relational self-esteem and collectivism and external—peer locus-of hope was significantly predicted by relational self-esteem, collectivism, and avoidant attachment style. No significant gender differences in locus-of-hope were found. Conclusions: The results provide further understanding about the construct of locus-of-hope and provide a foundation for future research to continue exploring the role of locus-of-hope in the development and expression of self-esteem and attachment profiles.

Telomere length in individuals with early pregnancy losses

Aim. Over the past decade, telomere biology has become an important topic in the field of human reproduction.We focused on the relationship between relative telomere length (RTL) and tendency to early pregnancy loss (EPL) in humans. Methods. RTL was measured in DNA isolated from the blood samples using a real-time polymerase chain reaction approach. RTL was examined in control group (C) (N=209) – women (CW) (N=107) and men (CM) (N=102) who had healthy pregnancies with no history of infertility or miscarriage, and in group with EPL (N=445) – women (EPLW) (N=223) and men (EPLM) (N=212) who had single or more EPL. RTL data were analyzed by gender and reproductive history. Results. Women (CW+EPLW) have significantly higher RTL that men (CM+EPLM) (1.74±0.06 in women and 1.40±0.05 in men, P=0.000053). Average RTL were significantly lower in CM compared to CW (CW: 2.27±0.12 versus CM: 1.15±0.08, P=0.0000001), and were similar in EPLW and EPLM (1.50±0.06 in EPLW and 1.53±0.06 in EPLM, P=0.47). The EPLW group had significantly lower RTL than control (EPLW: 1.50±0.06 versus CW: 2.27±0.12, P=0.0000001). Average RTL were significantly lower in CM compared to EPLM (1.15±0.08 in CM and 1.53±0.06 in EPLM, P=0.00006). Conclusions. Women with no history of EPL have longer telomere than men. Woman with EPL have shorter telomere that women without miscarriage. In EPL group women and men have similar telomere length.Keywords: telomeres, RT-PCR, gender, early reproductive loss.

The social-demographic characteristics and pandemic COVID-19 individual experience and their impact on vaccination attitude study aimed to determine the psychosocial interventions targets

A cohort cross-sectional study of the attitude of the population to vaccination against coronavirus infection COVID-19 was carried out using a specially designed questionnaire for mass filling, located on Internet resources 2 months after the start of mass vaccination in Russia. A total of 4172 people were examined at the age from 18 to 81 years. Among the respondents, there were different tendencies in relation to vaccination. Of the total sample, 35.7% of respondents consider vaccination useful, 32.2%—doubt its effectiveness, 8.7%—consider vaccination unnecessary, 12.2%—dangerous, indifference to vaccination was formed in 5.9% of respondents. They indicated that they do not plan to be vaccinated, 30.8%, postpones their decision until more remote data on the results and effectiveness of vaccination are obtained—34.7%, were vaccinated at the time of the study—12.2%. Young people are less focused on vaccination than middle-aged and older people. Among the factors that are associated with the attitude towards vaccination are age, gender, education, fear of possible complications, fear of contracting a coronavirus infection, concern for the health of their loved ones, anxiety about the current situation with coronavirus in general. The reports of scientists, doctors and experts in this field are essential for shaping attitudes towards vaccination. The study results should be considered as the targets for vaccination behavior improvement psychosocial interventions for different social and age population groups

An approach of renewable energy based on spatial patterns of radiation flux for solar thermal applications

The paper investigates about the aerosol index (AI) parameter obtained from the OMI during 2002–2016 concluded an East China, which have been discovered with a strong spatial heterogeneity in AI over the East China indicates variety of sources. We observed significant change in spatial AI increasing from the South to North attributed to impact for the powder unit’s ecstatic since Recompense sections. Spatial relative tendencies showed that the AI is the highest in most provinces. Further, the short-wave cloud radiative forcing (SWCRF) distribution revealed the highest (−180 Wm−2) and lowest (−110 Wm−2) values during JJA and DJF, respectively. While the long-wave CRF (LWCRF) values were seen prominent in almost the entire study area, with the high (60 W m−2) in JJA and low during MAM over the southeastern sites of study domain.

Accountability infrastructures: Pragmatic compliance inside organizations

AbstractWe trace the pragmatic turn in regulatory governance from the level of the state and civil society to the coalface of the regulated organization. Since the 1980s, an array of new regulatory models has emerged. These models, while distinct, are unified in two related tendencies. First, they support the devolution of responsibility for standard setting, program design, and enforcement to the regulated organization. This delegation of governance to the organization itself has catalyzed the creation ofaccountability infrastructureswithin organizations, a network of offices, roles, programs, and procedures dedicated to aligning the organization's operations with external standards, codes of conduct, ethical and normative expectations, and regulations. Second, the diverse regulatory models depend, often implicitly, on organizational accountability infrastructures that incorporate the tenets of pragmatist philosophy: inquiry through narration, adaptation to context, and problem‐solving through experimentation. Reviewing the empirical literature on organizational compliance, we find ample evidence of inquiry through narration at the organizational coalface. However, we find limited evidence of narrating plurality in the organization and narrating experimentation as problem‐solving, as these activities create tensions with internal and external parties who expect singular, stable representations of governance. These tensions reveal an important incongruity between pragmatic governance across organizations and pragmatic governance within organizations. We contribute to the regulatory governance literature by documenting this important shift in the locus of governance to the organizational coalface and by charting a new research agenda. We argue that examinations of regulatory governance should be retraced in three ways. First, attention should shift to the organizational coalface, recognizing and analyzing accountability infrastructures as the central contemporary mechanism of governance. Second, the long‐standing focus in regulatory studies onwhyparties comply should shift to understandinghowregulated parties manage themselves to achieve compliance. Third, analyses of compliance should examine the tensions in narrating adaptation and experimentation, and the implications of such tensions for the achievement of prosocial outcomes.

Computational study on the molecular interactions of tramadol with selected antioxidant and detoxification enzymes in Drosophila melanogaster

Tramadol is a potent analgesic medication prescribed worldwide for treatment of acute and chronic pains. Its relative tendency to be abused has become a public health concern. This study was designed to evaluate the molecular interactions of tramadol with selected antioxidant and detoxification enzymes of Drosophila melanogaster. The structures of CYP2D6, catalase and defense repressor 1 were retrieved from protein database (PubMed, Swiss model) while tramadol 2D structure was obtained from PubChem repository and prepared using LigPrep scripts as implemented in Small-Molecule Drug Discovery Suite of Schrödinger. 2D structure of tramadol was docked into the protein model binding site using Glide software from Schrodinger. The result revealed that, on the binding pocket of CYP2D6, tramadol and CYP2D6 inhibitor bind the protein pocket via hydrogen bond. The hydroxyl group of tramadol and the inhibitor interacts with the C=O groups of the residues Glu 128 and Lys 264 on the protein pocket respectively. Tramadol binds with higher affinity with a docking score of -4.581 kcal/mol when compared with the inhibitor which gave a docking score of -1.865 kcal/mol. With catalase, tramadol and the crystalized ligands were observed to exhibit hydrogen bonding with Ala 64 residue on the protein binding pocket with docking score of -2.348 kcal/mol and -3.431 kcal/mol respectively. The ability of tramadol to interact with these enzymes, strongly suggests that tramadol treatment may induce oxidative stress and at high dose might result in cellular toxicity. Therefore, the toxic effects of tramadol should be of concern despite the important role it plays in pain management.

Neurocognitive Measures of Self-blame and Risk Prediction Models of Recurrence in Major Depressive Disorder

BackgroundOvergeneralized self-blaming emotions, such as self-disgust, are core symptoms of major depressive disorder and prompt specific actions (i.e., action tendencies), which are more functionally relevant than the emotions themselves. We have recently shown, using a novel cognitive task, that when feeling self-blaming emotions, maladaptive action tendencies (feeling like hiding and feeling like creating a distance from oneself) and an overgeneralized perception of control are characteristic of major depressive disorder, even after remission of symptoms. Here, we probed the potential of this cognitive signature, and its combination with previously employed functional magnetic resonance imaging (fMRI) measures, to predict individual recurrence risk. For this purpose, we developed a user-friendly hybrid machine/statistical learning tool, which we make freely available. MethodsA total of 52 medication-free patients with remitted major depressive disorder, who had completed the action tendencies task and our self-blame fMRI task at baseline, were followed up clinically over 14 months to determine recurrence. Prospective prediction models included baseline maladaptive self-blame–related action tendencies and anterior temporal fMRI connectivity patterns across a set of frontolimbic a priori regions of interest, as well as including established clinical and standard psychological predictors. Prediction models used elastic net regularized logistic regression with nested 10-fold cross-validation. ResultsCross-validated discrimination was highly promising (area under the receiver-operating characteristic curve ≥ 0.86), and positive predictive values over 80% were achieved when including fMRI in multimodal models, but only up to 71% (area under the receiver-operating characteristic curve ≤ 0.74) when solely relying on cognitive and clinical measures. ConclusionsThis study shows the high potential of multimodal signatures of self-blaming biases to predict recurrence risk at an individual level and calls for external validation in an independent sample.