An isocaloric low-carbohydrate diet given to adolescent boys caused an increase in circulating levels of free fatty acids, glycerol and ketones and impairment of glucose tolerance. The fasting insulin levels as well as the response to glucose was either unchanged or reduced. The tenfold rise in ketones did not affect the insulin levels. Glucose and insulin values were closely related both on normal and low carbohydrate diets.
Read full abstract