Abstract The ocean responses to Typhoon Cimaron, which influenced the South China Sea (SCS) from 1 to 8 November 2006, are analyzed. Based on satellite-observed sea surface temperature (SST) and climatological temperature profiles in the SCS, mixed layer deepening, an important parameter characterizing turbulent mixing and upwelling driven by strong typhoon winds, is derived. Corresponding to the SST drop of 4.4°C on 3 November 2006, the mixed layer deepened by 104.5 m relative to the undisturbed depth of 43.2 m, which is consistent with a simulation result from a mixed layer model. Furthermore, baroclinic geostrophic velocity and vorticity are calculated from the surface temperature gradient caused by the typhoon. The negative vorticity, associated with the typhoon cooling, indicated an anticyclonic baroclinic circulation strongest at the base of the mixed layer and at the depth of 50 m, the geostrophic speed reached as high as 0.2 m s−1. Typhoon Cimaron proceeded slowly (1.7 m s−1) when it was making a southwestward turn on 3 November 2006, resulting in a subcritical condition with a Froude number (the ratio of typhoon translation speed to first baroclinic mode speed) of 0.6 around the maximum SST drop location and facilitating high SST cooling and mixed layer deepening because of the absence of inertial-gravity waves in the wake of the typhoon. Comparison of Argo buoy data with the climatological temperature suggests that the average uncertainty in the mixed layer deepening estimation caused by the difference between Argo and climatological temperature profiles is less than 10 m.