Precambrian metamagmatic complexes of the Zhingeldy and Kendyktas blocks of the Zheltau and Chu-Kendyktas terranes of the SW part of the Central Asian Orogenic Belt (CAOB) consist of predominant Neoproterozoic orthogneisses with the estimated protolith ages of ca. 790–800 Ma, and subordinate epidote and garnet amphibolites, metabasalts and metadolerites of the lower metamorphic grades. The orthogneisses are characterized by negative εNd(t) values of −12 to −4 with Nd model ages of 2.3–1.7 Ga, indicating their protoliths could have formed by a reworking of the Palaeoproterozoic crustal materials. Precambrian metavolcanic rocks in the studied region are rhyolites with the estimated crystallization ages of ca. 800–830 Ma, and are associated with metabasalts. Metasedimentary complexes in the studied region consist of intensively retrogressed garnet-mica schists interlayered with marmorized limestones, metasilicic rocks, epidote and garnet amphibolites and strongly altered eclogites. The inferred protoliths of the garnet-mica schists are terrigenous rocks accumulated during the latest Ediacaran – middle Cambrian and formed from Mesoproterozoic (ca. 1.0 Ga) and to a lesser extent Palaeoproterozoic felsic source rocks (ca. 1.6–1.7 Ga and ca. 2.5 Ga). The garnet-mica schists of the Kendyktas block have negative εNd(t) of −13.4 and a model age tNd(DM) of 2.2 Ga, implying formation of their protolith from Palaeoproterozoic crustal source. The studied Zheltau and Chu-Kendyktas terranes from the SW part of the CAOB have much in common in terms of Precambrian and Early Palaeozoic evolution and chemical compositions of the key rock types. The presence of the Early Precambrian rocks (Zheltau terrane), an abundance of the Late Mesoproterozoic (1000–1100 Ma) detrital zircons in the Ediacaran-Cambrian metasedimentary complexes and a wide distribution of the Late Neoproterozoic magmatism, are distinctive features of the studied terranes. We refer such Precambrian terranes of the western CAOB to the Ulutau-Moyunkum group where tectono-magmatic evolution is consistent with that observed from the northern part of the Tarim craton. Our results also aid comprehensive correlation of metamorphic complexes of the Precambrian terranes from the SW CAOB.