This review paper explores the optimization of talent management in creative industries through the utilization of advanced database systems. Traditional talent management methods often lack the structure and objectivity provided by modern database-driven approaches, which leverage comprehensive talent profiles, advanced search algorithms, and robust analytics to enhance decision-making processes. Case studies from industry leaders like Pixar, Wieden+Kennedy, and Ubisoft illustrate the practical benefits of these technologies in recruitment, development, and overall talent optimization. The paper also discusses challenges such as data quality, privacy concerns, and resistance to change, providing practical recommendations for overcoming these obstacles. Creative industries can significantly improve their talent management practices by fostering a culture of data-driven decision-making and investing in comprehensive talent databases. Future research directions include the impact of AI and machine learning, integration of emerging technologies, and longitudinal studies on the effectiveness of database-driven approaches.