Technological Fusion Research Articles

Organoids-On-a-Chip for Personalized Precision Medicine.

The development of personalized precision medicine has become a pivotal focus in modern healthcare. Organoids-on-a-Chip (OoCs), a groundbreaking fusion of organoid culture and microfluidic chip technology, has emerged as a promising approach to advancing patient-specific treatment strategies. In this review, the diverse applications of OoCs are explored, particularly their pivotal role in personalized precision medicine, and their potential as a cutting-edge technology is highlighted. By utilizing patient-derived organoids, OoCs offer a pathway to optimize treatments, create precise disease models, investigate disease mechanisms, conduct drug screenings, and individualize therapeutic strategies. The emphasis is on the significance of this technological fusion in revolutionizing healthcare and improving patient outcomes. Furthermore, the transformative potential of personalized precision medicine, future prospects, and ongoing advancements in the field, with a focus on genomic medicine, multi-omics integration, and ethical frameworks are discussed. The convergence of these innovations can empower patients, redefine treatment approaches, and shape the future of healthcare.

Exploring the convergence of Metaverse, Blockchain, and AI: A comprehensive survey of enabling technologies, applications, challenges, and future directions

AbstractThe Metaverse, distinguished by its capacity to integrate the physical and digital realms seamlessly, presents a dynamic virtual environment offering diverse opportunities for engagement across innovation, entertainment, socialization, and commercial endeavors. However, the Metaverse is poised for a transformative evolution through the convergence of contemporary technological advancements, including artificial intelligence (AI), Blockchain, Robotics, augmented reality, virtual reality, and mixed reality. This convergence is anticipated to revolutionize the global digital landscape, introducing novel social, economic, and operational paradigms for organizations and communities. To comprehensively elucidate the future potential of this technological fusion and its implications for digital innovation, this research endeavors to undertake a thorough analysis of scholarly discourse and research pertaining to the Metaverse, AI, Blockchain, and associated technologies. This survey delves into various critical facets of the Metaverse ecosystem, encompassing component analysis, exploration of digital currencies, assessment of AI utilization in virtual environments, and examination of Blockchain's role in enhancing digital content and data security. Leveraging articles retrieved from esteemed digital repositories including ScienceDirect, IEEE Xplore, Springer Nature, Google Scholar, and ACM, published between 2017 and 2023, this study adopts an analytical approach to engage with these materials. Through rigorous examination and discourse, this research aims to provide insights into the emerging trends, challenges, and future directions in the convergence of the Metaverse, Blockchain, and AI.This article is categorized under: Application Areas > Industry Specific Applications

Navigating the global landscape: the role of technological fusion and transnational knowledge in shaping standard-essential patents

ABSTRACT In the rapidly evolving landscape of global technology, the designation of Standard-Essential Patents (SEPs) plays a crucial role in shaping societal and technological strategies. This study explores the intricate relationship between technological fusion and its impact on the likelihood of a patent being recognised as an SEP. It further examines the moderating influence of international collaboration, as seen through the involvement of diverse international assignees and inventors. Utilising a comprehensive dataset of declared SEPs from 1977 to 2014, compared against a control group of non-SEPs, the study employs probit regression analysis to test its hypotheses. The findings suggest that an increased degree (i.e. criticality) of technological fusion within patents correlates with a decreased probability of SEP recognition. Additionally, this negative correlation is accentuated by factors associated with transnational knowledge collaboration, such as referencing international assignees and inventors. While rooted in the domain of patent analysis, the study's insights have significant implications for SEP developers, policymakers, and stakeholders at the nexus of technology and international collaboration, offering a novel perspective on the complex interplay between technological innovation, global knowledge sharing, and SEP recognition.

მულტიმედიური ჟურნალისტიკის განვითარება საქართველოში

As a result of the modernization of the information space and various information technologies, we have the opportunity to watch wars, natural disasters, sports events and others on television. Every day we receive international news from all over the world. A characteristic feature of the Internet today is media convergence, the technological fusion of content in various mass media. In recent years, the Internet has truly become a hub of convergence, a place where music, television shows, radio stations, newspapers, magazines, books, and movies are created, distributed, and presented. Today, computers and mobile phones are the most popular digital devices for online convergence, which can themselves create or stream books, movies, music, video games, and any other form of digital media. Today's global media market does not consist of any particular place, space or habit, it no longer has dimensions such as time and borders. It is permanently established in the digital world and cyberspace, on the screens of all computers and interactive televisions connected to the Internet, as well as mobile phones and still unbelievable inventions. In the digital age, where technologies are evolving every day, it is very important to adapt to innovations and news in time. In the modern world, the introduction of technological innovations in the means of mass communication is taking place rapidly, which has completely changed the forms of information dissemination. Today, accuracy, promptness, flexibility and interactivity are the key elements of modern multimedia journalism.

Surfactant-Mediated Highly Conductive Cellulosic Inks for High-Resolution 3D Printing of Robust and Structured Electromagnetic Interference Shielding Aerogels.

Technological fusion of emerging three-dimensional (3D) printing of aerogels with gel processing enables the fabrication of lightweight and functional materials for diverse applications. However, 3D-printed constructs via direct ink writing for fabricating electrically conductive structured biobased aerogels suffer several limitations, including poor electrical conductivity, inferior mechanical strength, and low printing resolution. This work addresses these limitations via molecular engineering of conductive hydrogels. The hydrogel inks, namely, CNC/PEDOT-DBSA, featured a unique formulation containing well-dispersed cellulose nanocrystal decorated by a poly(3,4-ethylene dioxythiophene) (PEDOT) domain combined with dodecylbenzene sulfonic acid (DBSA). The rheological properties were precisely engineered by manipulating the solid content and the intermolecular interactions among the constituents, resulting in 3D-printed structures with excellent resolution. More importantly, the resultant aerogels following freeze-drying exhibited a high electrical conductivity (110 ± 12 S m-1), outstanding mechanical properties (Young's modulus of 6.98 MPa), and fire-resistance properties. These robust aerogels were employed to address pressing global concerns about electromagnetic pollution with a specific shielding effectiveness of 4983.4 dB cm2 g-1. Importantly, it was shown that the shielding mechanism of the 3D printed aerogels could be manipulated by their geometrical features, unraveling the undeniable role of additive manufacturing in materials design.

Safeguarding Tomorrow: Strengthening IoT-Enhanced Immersive Research Spaces with State-of-the-Art Cybersecurity

In an era where technological progress is shaping the very foundations of our world, the convergence of Internet of Things (IoT), augmented reality (AR), and virtual reality (VR) stands as a harbinger of profound change in research and education. This transformation finds its embodiment in IoT-Enhanced Immersive Research Spaces (IoT-IRS), an emerging frontier that melds these technologies into immersive environments for learning and research. As we navigate this exciting terrain, it's crucial to recognize not only the potentials but also the challenges. While IoT-IRS offers the allure of collaborative immersion, real-time data analysis, and expansive exploration, it simultaneously exposes vulnerabilities to cyber threats. This paper embarks on a comprehensive exploration, delving into the intricate interplay between IoT, AR, and VR within the dynamic domain of IoT-IRS. Amidst the captivating prospects, the paper consistently underscores the pivotal role of cybersecurity. It emphasizes the pressing need to fortify data integrity, preserve privacy within shared virtual spaces, and establish resilient barriers against the ever-evolving cyber landscape. In essence, this paper navigates through the landscape of technological fusion and immersive possibilities, all the while remaining steadfast in its commitment to anchor these advancements in a bedrock of cybersecurity that mirrors the innovation and resilience of the technologies it safeguards.

Intelligent Computing: The Latest Advances, Challenges, and Future

Computing is a critical driving force in the development of human civilization. In recent years, we have witnessed the emergence of intelligent computing, a new computing paradigm that is reshaping traditional computing and promoting digital revolution in the era of big data, artificial intelligence, and internet of things with new computing theories, architectures, methods, systems, and applications. Intelligent computing has greatly broadened the scope of computing, extending it from traditional computing on data to increasingly diverse computing paradigms such as perceptual intelligence, cognitive intelligence, autonomous intelligence, and human–computer fusion intelligence. Intelligence and computing have undergone paths of different evolution and development for a long time but have become increasingly intertwined in recent years: Intelligent computing is not only intelligence oriented but also intelligence driven. Such cross-fertilization has prompted the emergence and rapid advancement of intelligent computing. Intelligent computing is still in its infancy, and an abundance of innovations in the theories, systems, and applications of intelligent computing is expected to occur soon. We present the first comprehensive survey of literature on intelligent computing, covering its theory fundamentals, the technological fusion of intelligence and computing, important applications, challenges, and future perspectives. We believe that this survey is highly timely and will provide a comprehensive reference and cast valuable insights into intelligent computing for academic and industrial researchers and practitioners.

Mapping technological trajectories and exploring knowledge sources: A case study of E-payment technologies

Technology trajectory provides valuable information on technological development and its potential impact. This study takes E-Payment technology as an example by presenting the technological development trajectory, and by exploring the contribution of knowledge sources from different regions and various technical fields. In the process of technological trajectory evolution, different trajectory phenomena will appear in different periods, such as convergence, lock-in, and dominance in technological development. To find out the phenomenon of electronic payment technology trajectory, this study uses a patent database of the United States Patent and Trademark Office (USPTO) as a data source. It uses keywords to conduct a patent search, a patent citation data set is established, and the main path analysis (MPA) is performed. According to the research results, the E-payment industry technology is dominated by the United States from the country's patent ownership perspective. The combination of American Qualcomm and Firethorn Mobile has the key technology leading position on the main path of technological development. From the perspective of patentees, VISA and MasterCard have invested the most in technology R&D to show their leading position in future technology development. According to the main path analysis of patents, the research results showed that from the year 1983 to the year 2007, technology had developed diversified, and knowledge flow in related technical fields had already expanded. In the year 2008, technological development changed with technological fusion, and the technology was locked in. After 2013, a patent for “identity verification” on transaction security appeared on the key main path. After the emergence of this core patent technology, a technological explosion occurred. Various technologies developed rapidly during this period and had continued to occur so far. Since 2008, the number of patent announcements has been in a stage of high technological growth so it can be regarded as the growth stage of the technology life cycle. In addition to the main technical analysis, payment security is the core technology of the entire payment industry. Near-field communications (NFC) technology has the most critical development trend among the related technologies developed, followed by cloud computing-related technologies.

Correlation between BIM data creation and big data attributes in construction

Considerable effort to leverage digital data was exerted as construction adopts innovative work processes. Among these, Building Information Modelling (BIM) sat at the backbone of digital strategy, with the capability to create huge digital data through its realizable multifunctionality and integration capacity. Ubiquitous to construction, the explosion of huge data through BIM sparked the relevancy of big data. While it was logical that the volume of BIM data swells from the adoption of BIM, a question remains whether the creation of BIM data conjures to big data progression. Hence, this research aimed to examine the relationship between BIM data creation and big data attributes. The study was carried out by a combination of literature reviews and a questionnaire survey. The outcome indicates two groups which are cost and operation and maintenance (OM) data had a very low correlation due to irrefutable reasons, the remaining material, design and schedule data reflected a strong positive relationship. Therefore, the outcome reflects the earlier attestation of the technological fusion in construction.

Japanese industrial technological structure based on the number of patent applications by technical field

PurposeThis research outlines the technological structure of the entire Japanese manufacturing and service industry using the patent information from research and development (R&D) activities to set R&D goals.Design/methodology/approachBy analyzing the technological development capability of individual companies, the direction of the companies' R&D activities and current state of technological fusion between them can be understood. A group of companies participating in a particular product/service market must have the same technological development capabilities. As a result, the ratio of patent applications by a company to the total number of applications in a technical field will be similar across companies. This study uses the inter-company correlation coefficient of the ratio of patent applications by technical field as an index of technological development capability. A total of 167 major companies covering the major industries of Japan were analyzed. The analysis period was 15 years from 2004 to 2018, and the technical fields were rearranged to 42 fields with reference to the International Patent Classification (IPC)-Technology Concordance used by the World Intellectual Property Organization (WIPO). Considering the fluctuation in patent application opportunities, the number of patent applications was collected for at least three years for the analysis of patent applications by technical field, company and industry.FindingsExamining the entire Japanese industry, the research found that chemicals, ceramics, non-ferrous metals and electrical/electronic equipment act as intermediaries between the respective groups and are linked to the transportation equipment, electrical/electronic equipment and information and communication services industries that are currently driving the Japanese economy. However, the technical connections between these groups are relatively loose. Over the last 15 years, the propagation structure of technical knowledge information has not changed. The progress of technological fusion remains within the scope of commerce and is conditioned by commerce.Originality/valueStudies focusing on the technological development capability between companies and the technological structure of the Japanese manufacturing and service industries are almost non-existent since 2000 when Japan's economic growth slowed. The analytical methods presented in this research can be applied to individual companies to gain an understanding of technical positions of companies and can be useful for planning a technical environment, business or R&D strategy.

Natura Non Facit Saltus: Challenges and Opportunities for Digital Industrialisation Across Developing Countries

In this paper, we discuss the challenges and the opportunities faced by developing countries that want to join the so-called Fourth Industrial Revolution (4IR). We first point out that the current discourse on 4IR is often based on poor understanding of the true nature of the phenomenon. Emphasising that many of the so-called 4IR technologies have been there and evolving rapidly in the last half a century, we argue that what defines 4IR is the fusion of these technologies. Given this, we argue, rather than trying to master particular 4IR technologies, developing countries should first focus on acquiring what we call the foundational capabilities, i.e. the capabilities to learn new technical and organisational solutions and apply them in creative and flexible ways. Using this perspective, we then discuss in great detail how different 4IR technologies are re-shaping each industry and creating new industries through technological fusion, while discussing how these changes are affecting the opportunities and challenges faced by developing countries for industrial development. We conclude the paper by discussing the implications of our findings for industrial policy in developing countries.

UAV systems for multipurpose heterogeneous networks: a review of design, development and performance

The technological fusion between wireless sensor networks and the UAS capabilities allows a fast, easy, and inexpensive deployment with multipurpose heterogeneous networks like a communication system for replicable nodes. For a UAV proposed, this paper studies the heterogeneous communication networks with their design, development, and performance where the configurations and design requirements, systems, subsystems required, preliminary sizing study, and services and capabilities were analyzed. Consequently, preliminary dimensions such as wingspan, length, height, maximum take-off weight, and performance specifications were obtained to give introductory considerations about the avionics, routing protocols, and human interaction which infers in an implementation challenge but with several advantages in military and civil applications.

Handheld Aptasensor for Sandwiched Detection of Chloramphenicol

Chloramphenicol(CAP) is an antifungal agent approved for use in aquarium. However, CAP residue imparts serious adverse effect on human health as well as the ecology. Thus, keeping track of CAP in aquatic products and its environmental metabolites are of great importance. Herein, we developed a novel and neat electrochemical aptasensor for the detection of simulated CAP residual in a sandwich fashion. The screen-printed carbon electrode was employed as the sensing platform and electrodeposited with peculiar nanogolds to enhance the electrochemical performance. For the specific recognition of such small target, a pair of chloramphenicol-binding aptamers, the primary Apt1 and the secondary Apt2, were tailored as an artificial single-chained antibody couple, of which the thiolated Apt1 stood on the coated working substrate to capture the analyte, while the biotinylated Apt2 rallied the signal output. In the presence of CAP, Apt1 at the lower place cooperated with the upper Apt2 pinched CAP together. After that, the reporter avidin-conjugated horseradish peroxidase associated atop the mounted biotin labels, resulting in an electrocatalytic amplification. In whole, this modular biosensing construction would set a paradigm not just for practicable checkpoint quarantine or point-of-care testing, but potentially adaptable for technological fusion with “Internet Plus” and “Internet of Things”.

Recommendation of Technological Fusion and Field Fusion

Recommendation of Technological Fusion and Field Fusion

STIMULATING DIGITAL LITERACY PARTICIPATIONS’ FRAMEWORKS: INNOVATIVE AND COLLABORATIVE LANGUAGE PROJECTS

This paper highlights educators’ innovativeness as digital participants and facilitators adapting themselves in current global educational changes as upshots of technological fusion that influences instructional variation for learners’ real–world. It is perceived that teachers’ flexibility to evolving trends in current instructions is crucial. It is fundamentally a structured expository concept on teachers and students’ development reinforced by theories and researches’ investigated outcomes toward the challenges of emerging pedagogic phenomena sustained by model project- tasks designed for innovative, collaborative and digital literacy participations. This inquisition attempts to respond to the succeeding inquiries: Why do educators innovate in the 21st century? Is professional development necessary to situate contemporary learning? What are the roles of technology and digital literacy for innovative and collaborative instructions? What are the features of digital literacy and digital participations and how do participants pragmatically engage? What are some collaborative and innovative projects that define digital participations? Are these tasks sustained by current and duly sanctioned educational principles and frameworks? Do these tasks conform to the scope of integrated digital literacy taxonomy framework? Do the framework and principles produce practical assessment of outcomes to improve future project-based tasks? An empirical investigation is recommended to test the significance and correlation among students’ project performance towards their attitudes and efficacy on digital literacy. Article visualizations:

Teachers’ Beliefs on Technological Fusion in Teaching ESL Students

Studies on the effectiveness of technology have shown that it enhances students in language learning and helps gain their involvement. Nevertheless, there is still resistance among teachers in using technology in the language classrooms due to the rapid advancements of technology. The aim of the study reported in this article was therefore to gather testimonial insights on teachers’ beliefs about technology and its fusion to illuminate how English as a second language (ESL) teaching and learning is eased and made meaningful in classrooms. This paper reports on a case study that looks into primary school teachers’ beliefs on technological fusion in teaching ESL students. Data were collected from three teachers of different teaching experiences through interviews and observations and themes were generated through constant comparative and thematic analysis; assisted with the use of ATLAS ti.7 software. Findings indicate that despite positive beliefs that the fusion of technology assists language teaching and learning, not all teachers embrace technology in their classrooms as schools especially in rural areas lack facilities to aid the use of technology. This study implies that there is a need to equip all schools with devices and equipment that aid the fusion of technology in language teaching.

HDInsight4PSi: Boosting performance of 3D protein structure similarity searching with HDInsight clusters in Microsoft Azure cloud

3D protein structure similarity searching is one of the important processes performed in structural bioinformatics, since it allows for protein function identification and reconstruction of phylogeny for weakly related organisms. Due to the complexity of 3D protein structures and exponential growth of protein structures in public repositories, like the Protein Data Bank, the process is time-consuming and requires increased computational resources. This causes the necessity to prepare computer systems to be able to deal with such huge volumes of macromolecular data.In this paper, we show how 3D protein structure similarity searching can be performed in parallel by distributing MapReduce jobs on the HDInsight cluster in Microsoft Azure commercial cloud. Our solution combines the use of two important computing paradigms that gain popularity in recent years—Hadoop/MapReduce and Cloud computing. Our experiments performed with the use of the whole repository of protein structures from Protein Data Bank confirm that such a technological fusion is very beneficial and can be successfully applied when performing time-consuming computations over biological data. Moreover, appropriate preparation of data allows to reduce the time needed for computations and significantly accelerates the similarity searching.

Drones, Vertical Mediation, and the Targeted Class

This article explores how US military drone use has (re)organized everyday life in some parts of the world by producing a new disenfranchised targeted class through practices of vertical mediation. The author argues that the critical analysis of drone technology and warfare needs to extend beyond Paul Virilio’s important recognition of the technological fusion of the airplane, the camera, and the gun to include more careful consideration of the vertical fields, material resources (fuel, labor, lands, hardware, networks, data, sky, orbit) and hierarchies of command that enable aerial restructuring of life on earth. Just as it is important to recognize how drone warfare is organized through systems of remote-control, simulation, and gaming, it is equally important to acknowledge its grounded and embodied dimensions, the landscapes and auto-topographies that register and archive the drone’s uses and affects.

Efficient Clustering Simulator for Hierarchical Management of High-Risk with Wellness

In recent years, various research fields, such as Information Technology (IT), Nano Technology (NT), Bio Technology (BT), Culture Technology (CT), Space Technology (ST), and Environment Technology (ET), have fused to solve a large number of issues in the real world. In particular, service solutions have emerged by combining IT and BT in the area of wellness research. In addition, major studies have conducted on wellness. These include implanting medical technology into the human body, sensor recognition technology that detects various changes in the human body, sensor miniaturization technology that attaches sensors to the human body, and high-risk group monitoring technology that uses various pieces of sensor data from the human body. In particular, the high-risk group has many different types of diseases, such as depression, suicide, diabetes, high blood pressure, and cancer, which be divided into mental and physical illnesses. It is highly important to manage patients in the high-risk group hierarchically because of the critical nature of their diseases. Therefore, although technological fusion has achieved a wireless body area network (WBAN), it has mainly concentrated on measurement via sensors, coverage, and communication range. Therefore, this paper proposes a High-risk Hierarchical Clustering Simulator (H2CS) for the hierarchical management of patients in high-risk groups. The H2CS provides hierarchical management functions by actively recording high-risk level, based on the grades and distances of high-risks.

Approaches to Technological Fusion of “ICT × Energy × Building” and New R&D Bases

Approaches to Technological Fusion of “ICT × Energy × Building” and New R&D Bases