Introduction: The gold standard treatment of early gallbladder carcinoma is radical cholecystectomy. This procedure involves en-block resection of the adjoining liver bed. Hemostasis control is the major concern during liver resection, particularly in laparoscopic approach. Mortality and morbidity are clearly associated with the amount of blood loss.1 The harmonic scalpel is commonly used for liver resection during the laparoscopic approach. However, this technique has been shown to have more incidence of bile leakage.2 Radiofrequency (RF) energy has been broadly used to ablate local unresectable liver tumor by causing coagulative necrosis of the liver parenchyma tissues.3 This alternating current also causes thrombosis and coagulation of the small blood vessels, which exhibits its potential in bloodless liver resection. RF-assisted liver resection shows minimal blood loss in human and animal model experiences.4–6 This novel technique is utilized during laparoscopic radical cholecystectomy to minimize blood loss in liver bed resection. The patient was a 38-year-old lady who presented with epigastric pain for 3 years. The pain was worsening. Abdominal ultrasound showed a large polypoidal mass measuring 2 cm within the gallbladder. Computed tomography of the abdomen confirmed the ultrasound finding showing a large polypoidal mass within the gallbladder without invasion to the liver. RF energy-assisted laparoscopic radical cholecystectomy was performed for her. Methods: This video illustrates the technique of laparoscopic radical cholecystectomy assisted by RF energy. First, the procedure was proceeded as laparoscopic cholecystectomy. The fundus of the gallbladder was retracted. Callot's triangle was dissected. Once the cystic vessels and duct were identified, they were clipped and divided. Endoloop was applied to the neck of gallbladder for better retraction later. Resection margin was marked with hook by electrocautery, which is 2 cm around the liver bed margin. RF energy was applied to the planned resection margin. Coagulative desiccation was performed using a cooled-tip RF probe and a 500 kHz generator (Radionics Europe, NV, Wettdren, Belgium). The RF probe was inserted 2 cm in depth. Once coagulative desiccation had been achieved, the probe was then advanced 1 cm along the resection margin. When hemostasis was secured with complete ablation of the resection margin, a sharp transaction of the coagulated plane was done by using scissors. No clamping of the vascular pedicles was necessary. Any bleeding from the resection margin during scissor transection was ablated again until satisfactory hemostasis was achieved. The estimated blood loss was less than 10 mL. Results: Postoperatively, patient's recovery was uneventful. No significant drop in hemoglobin was noted. The total ward stay was 3 days. The patient was back to normal daily activity in 5 days. Histopathologically, polyps within the gallbladder were consistent with a well-differentiated (polypoidal) adenocarcinoma. The gallbladder showed chronic cholecystitis with cholesterol polyps. Liver tissue showed no evidence of malignancy. The patient did not require any adjuvant therapy. Conclusion: RF ablation can be a useful adjunct in laparoscopic radical cholecystectomy during liver bed resection. This safe, fast, and simple technique is effective in minimizing blood loss. It potentially reduces the conversion rate from laparoscopic approach to open method once suspected early gallbladder is encountered during laparoscopic cholecystectomy. No competing financial interests exist. Runtime of video: 7 mins 10 secs