Cows are culled at a relatively low age, which causes considerable economic loss. The annual culling rate in the Netherlands has increased from 18.8 per cent in 1951 to 25-30 per cent of the average number of cows in more recent years. The productive life is now about 3.5 years. On the thirty farms of the program group and thirty-one farms of the control group, the main reasons for culling were reproductive failure followed by mastitis and teat injuries. About 60 per cent of culling was due to health problems, the other 40 per cent to low productive capacity, old age, poor workability etc. The annual culling rate varied per farm per year but also per month. The moment of culling in the current lactation, the slaughter value and the age differed per reason. The calculated loss of forced replacement consists of reduction in both production prior to culling and slaughter value. Additionally, there is an idle production period due to lack of an immediate replacement. The biggest loss is caused by lost future income. There was a considerable difference per farm in the loss caused by culling for health problems. A low culling rate due to health problems was associated with longer longevity and a relatively lower loss. Tangible effects due to changes in the farm culling policy may not be evident for some years. The reduction in loss of culling in the program farms compared with the controls was small because the duration (2 1/2 years) of the herd health and management program was too short.(ABSTRACT TRUNCATED AT 250 WORDS)