The fracture toughness of AA6061 sheets subjected to pre-cryorolling and room-temperature pre-rolling with varying reductions (5 %, 10 %, 15 %, and 20 %) followed by bake hardening was investigated. In the direction parallel to the rolling direction (R-T), the unit crack initiation energy (UIE) of the pre-cryorolled samples after bake hardening exhibited an increase of 0.8–6 % compared to samples without pre-rolling. In contrast, the UIE of the room-temperature pre-rolled samples displayed a varying degree of decrease. This difference can be attributed to the smaller mean grain size in the pre-cryorolled samples compared to the room-temperature pre-rolled samples. Due to work hardening, the crack propagation resistance of the pre-rolled samples was diminished, as evidenced by a decrease in crack propagation energy (UPE) with increasing reduction. The variation trends of UIE and UPE in the direction perpendicular to the rolling direction (T-R) were similar to those observed in the R-T direction. The fracture mechanism of the samples during the tearing process involves a combination of intergranular and transgranular fractures. However, samples in the R-T direction exhibit higher resistance to crack propagation compared to those in the T-R direction, which is reflected in the larger UIE and UPE. The greater resistance in the R-T direction can be attributed to the significant elongation of grains prior to fracture, resulting in a higher degree of plastic deformation in the region near the crack. Additionally, the proportion of transgranular fracture along the crack propagation path is greater in the R-T direction.