As a concerted move toward closer integration of the clinical and preclinical aspects of the undergraduate medical curriculum at the University of Auckland, the Department of Anatomy with Radiology has implemented a number of clinical procedures, pathological observations and diagnostic methods into the course resulting in a structured program of clinically based teaching of gross anatomy to second- and third-year medical students. The recently developed method of E12 epoxy resin sheet plastination of sectioned cadaver specimens has expanded the learning process twofold, firstly as a developmental microscopy teaching aid enabling us to link histological slides directly to gross anatomical specimens and secondly as a radiographic training tool in the correlation of clinical imaging techniques of magnetic resonance (MRI) and computed tomography (CT) with the teaching of gross anatomy. The direct comparison between E12 serial sectioned cadaver specimens and the equivalent MRI and CT images provides the student with a much clearer understanding of anatomical structures in relation to clinical diagnosis.