Since the founding of the People's Republic of China, the epidemiological textbooks in China have gone through an all-round development consistently, from nothing to something, from paper to multimedia. After the reform and opening up, especially after the 18th National Congress of the Communist Party of China (CPC), in order to meet the needs of training multi-level public health talents, a group of epidemiologists, represented by professor Qian Yuping, Wu Xike, Li Liming, Zhan Siyan, et al, have always devoting themselves to the construction of epidemiological textbooks, so that the theory, teaching and scientific research of epidemiology had their own series of specialized textbooks. For nearly 20 years, epidemiological textbooks are obviously updated and improved under the convergence of new technology and media. Digital resources, such as CD, Mooc and electronic schoolbag, together with traditional paper textbooks, perfectly contribute to the modern comprehensive three-dimensional epidemiological textbooks and lay a solid foundation for talent cultivation, discipline construction, scientific research and disease prevention and control.