Objective: To assess patients' physiological and psychological aspects with full-mouth dental implantation.Methods: A cross-sectional observational study was conducted on 27 patients >30 years old who had full mouth dental implantation from the College of Dentistry Post Graduate Clinic, Shorsh Dental Teaching Center, and Researchers' Private Clinic from August 2021 to August 2022. Patients' feedback about the OHIP-14 questionnaire was assessed.Results: The mean±SD (standard deviation) age was 57.7±12.2 years, and male to female ratio was (1.1:1). Regarding their demographic characteristics, 33.3%, 44.4%, 37%, and 77.8% of patients were retired, had finished institute education, were unemployed, and were from Sulaymaniyah, respectively. In addition, 70.4%, 70.4%, 74.1%, 74.1, and 63% of patients irregularly visited the dentist, used toothbrushing once daily, did not use a mouth rinse, and had either Diabetes mellitus or hypertension or both, respectively. Meanwhile, 18.5%, 11.1%, 11.1%, and 3.7% of patients suffered from temporomandibular (TM) joint clicking, tenderness, limited mouth opening, and bad occlusion, respectively. Functional limitations and psychological disabilities were not well improved, but for other OHIP-14 questionnaire items only 3.7-7.4% of patients reported undesired outcomes.Conclusions: Patients with full-mouth dental implantation reported improvements regarding some items of the OHIP-14 questionnaire. However, in the current study, functional limitations and psychological disabilities were less improved than shown in the literature.