Potentially toxic metal(loid) assessment of tea and tea garden soil is a vital guarantee of tea safety and is very necessary. This study analyzed the distribution of seven potentially toxic metal(loid)s in different organs of the tea plants and soil at various depths in the Yangai tea farm of Guiyang City, Guizhou Province, China. Although soil potentially toxic metal(loid) in the study area is safe, there should be attention to the health risks of Cu, Ni, As, and Pb in the later stages of tea garden management. Soil As and Pb are primarily from anthropogenic sources, soil Zn is mainly affected by natural sources and human activities, and soil with other potentially toxic metal(loid) is predominantly from natural sources. Tea plants might be the enrichment of Zn and the exclusion or tolerance of As, Cu, Ni, and Pb. The tea plant has a strong ability for absorbing Cd and preferentially storing it in its roots, stems, and mature leaves. Although the Cd and other potentially toxic metal(loid)s content of tea in Guizhou Province is generally within the range of edible safety, with the increase of tea planting years, it is essential to take corresponding measures to prevent the potential health risks of Cd and other potentially toxic metal(loid)s in tea.