Event Abstract Back to Event A Computational Neuromotor Model of the Role of Basal Ganglia in Spatial Navigation Deepika Sukumar1* and Srinivasa V. Chakravarthy1 1 Indian Institute of Technology, India Navigation is a composite of wandering and goal-directed movements. Therefore a neuromotor model of navigation must include a component with stochastic dynamics and another which involves hill-climbing over a certain “salience” function. There are models of navigation that incorporate both basal ganglia (BG) and hippocampus, the brain circuits that subserve two forms of navigation – cue-based and place-based respectively. But existing models do not seem to identify the neural substrate for the stochastic dynamics necessary for navigation. We propose that the indirect pathway of BG is the substrate for exploratory drive and present a model of spatial navigation involving BG. We formulate navigation as a Reinforcement Learning (RL) problem and model the role of BG in driving navigation. Actor, Critic and Explorer are the three key components of RL. We follow the classical interpretation of the dopamine signal as temporal difference error, the striatum as the Critic and the motor cortex (M1) as the Actor. The subthalamic nucleus and Globus Pallidus externa loop, which is capable of complex neural activity, is hypothesized to be the Explorer. The proposed model of navigation is instantiated in a model rat exploring a simulated circular Morris water maze. A set of eight poles of variable height placed on the circumference of the pool provide the visual orienting cues. An invisible platform is placed at one end of the pool. Guided by appropriate rewards and punishments, the model rat must search for the platform. The following are the RL-related components of the model: Input: The rat’s visual view consisting of some poles, coded as a “view vector” is presented to both M1 and BG.Reward: As the rat randomly explores the pool, accidental arrival at the platform results in reward and collision with the surrounding walls in punishment.Critic: A function, V(t), of the view vector is trained by the dopamine signal (TD error). Dopamine signal: Dopamine signal is used to switch between the direct and the indirect pathways of BG.Stronger dopamine signal increases the activity of the direct pathway (DP), while reducing the activity of the indirect pathway (IP). Critic Training: The Critic is trained in multiple stages, starting with a small discount factor and increasing it with time. Actor (M1) training: The perturbations to M1 from BG, in combination with the dopamine signal, are used to train M1.Output: A weighted sum of the outputs of M1 and BG determines the direction of the rat’s next step. Thus in the present model, dopamine modulates activity within BG, and BG modulates learning in M1. A novel aspect of the present work is that the substrate for the stochastic component is hypothesized to be the IP of BG. Future developments of this model would include two forms of spatial-coding in hippocampus (path-integration and spatial-context mapping) and their contribution to navigation. Conference: Bernstein Conference on Computational Neuroscience, Frankfurt am Main, Germany, 30 Sep - 2 Oct, 2009. Presentation Type: Poster Presentation Topic: Decision, control and reward Citation: Sukumar D and Chakravarthy SV (2009). A Computational Neuromotor Model of the Role of Basal Ganglia in Spatial Navigation. Front. Comput. Neurosci. Conference Abstract: Bernstein Conference on Computational Neuroscience. doi: 10.3389/conf.neuro.10.2009.14.039 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 26 Aug 2009; Published Online: 26 Aug 2009. * Correspondence: Deepika Sukumar, Indian Institute of Technology, Madras, India, deepika.sukumar@gmail.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Deepika Sukumar Srinivasa V Chakravarthy Google Deepika Sukumar Srinivasa V Chakravarthy Google Scholar Deepika Sukumar Srinivasa V Chakravarthy PubMed Deepika Sukumar Srinivasa V Chakravarthy Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.
Read full abstract