TCM Diagnosis Research Articles

The status of Chinese medicine in coronary heart disease with anxiety and depression status

Depression and anxiety, as adverse factors affecting the paroxysm and prognosis of coronary heart disease, can not only aggravate the development of coronary heart disease, but also affect its treatment and prognosis. Therefore, this paper aims to review the literatures on TCM diagnosis and treatment of coronary heart disease with anxiety and depression in recent years, and to understand the current status of treatment, pathogenesis, dialectical classification and dialectical treatment. Key words: Coronary heart disease; Anxiety; Depression; Chest Discomfort; Melancholia; Therapy (TCM); Review

Application Research of Knowledge Mapping in TCM Health

Objective: In the field of Web search and general field, a large number of large-scale knowledge map libraries have been formed, but theconstruction of knowledge maps in the fields of medicine and traditional Chinese medicine is still in its infancy, although there are large-scalemedical ontology libraries. However, there are still few studies on the construction of specialized medicine, especially the TCM knowledgemap library, which greatly hinders the information application and sharing of TCM concept knowledge.Methods: For the map construction of the main conceptual entities such as symptoms, syndromes, diseases and traditional Chinese medicinein the field of traditional Chinese medicine, the corresponding schema pattern (Schema) was designed to determine the basic categories,category attributes and semantic relations of the map. The Protege Ontology Editor adds constraints to the entities in the TCM knowledgemap and their relationships, and uses Protege to graphically display some of the knowledge in the knowledge map. Finally, based on theformed knowledge map, the open-source toolkit Jena and the inference rules based on the logic of TCM diagnosis and treatment are used tocarry out the model analysis and application of knowledge reasoning based on knowledge map.Conclusion: Knowledge graph is carried out in the era of big data. The important data resources of knowledge management and applicationhave become the key technical basis for search engine semantic retrieval and knowledge-based reasoning and decision-making in variousfields. By integrating various data sources, this paper studies the construction of TCM health knowledge maps with symptoms, syndromes,diseases and medicines as the main entities. The analysis results show that it has certain feasibility and application value.

1695P - Acupuncture for peripheral neuropathy in cancer patients: TCM diagnosis as a predictor of treatment response

1695P - Acupuncture for peripheral neuropathy in cancer patients: TCM diagnosis as a predictor of treatment response

Usefulness of left ventricular strain analysis in patients with takotsubo syndrome during acute phase.

Takotsubo syndrome (TTS) is peculiar clinical condition often resembling an acute coronary syndrome and mostly affecting postmenopausal women after a stressful trigger. TTS was initially thought to be a relatively benign condition. However, current data have shown it may be associated with considerable inpatient morbidity and carry a small, but important, mortality risk. We hypothesized that left ventricular (LV) regional and global longitudinal strain (GLS) assessed with 2D speckle tracking echocardiography could identify early systolic functional impairment and predict in-hospital cardiovascular events. We conducted a retrospective descriptive study reviewing patients with the discharge diagnosis of TCM between 2003 and 2016 at our institution. One hundred patients with TSS met the Modified Mayo Clinic criteria. Using 2D speckle tracking echocardiography, two independent cardiologists assessed the LV GLS as well as the longitudinal strain (LS) of 7 individual segments [basal-septal (BS); mid-septal (MS), apical-septal (AS), apex, basal-lateral (BL), mid-lateral (ML), and apical-lateral (AL)]. The inter-observer variability was <5%. Mean age was 69.1years, 87% were females, and 53% were African Americans. Mean initial LV EF was 32%±9.8%. In univariate analysis, patients with worse BL, ML, and GLS profiles (means: -5.7; -3.3, and -4, respectively) had higher in-hospital mortality (P<.05). Worse BL and ML profiles (means: -8.6 and -7.3, respectively) were associated with higher prevalence of MACE (major adverse cardiovascular outcomes) (P<.05). In a multivariate analysis, mid-lateral strain≥-7 and basolateral strain≥-10 were independent predictors of in-hospital mortality and MACE+in-hospital heart failure, respectively. Assessment of LV global and segmental longitudinal strain by speckle tracking has important prognostic value in the acute phase of TTS. Additional large-scale studies will be needed to confirm our findings.

Expert consensus on TCM diagnosis and treatment of ascites due to cirrhosis (2017)

Expert consensus on TCM diagnosis and treatment of ascites due to cirrhosis (2017)

The TCM diagnosis and treatment guideline of the wind of four fossae: a Delphi concensus study

Objective To evaluate the common traditional Chinese medicine syndrome types, therapies and formulas of the wind of four fossae. This will provide reference for the formulation of the guideline for the diagnosis and treatment of traditional Chinese medicine in the wind of four fossae. Methods Delphi method using questionnaires were developed based on literature about TCM syndromes and treatment of the wind of four fossae. The questionnaire were sent to 25 experts nationwide for 2 rounds. The database of the collected data was established. The mean, full score ratio, rank sum and coefficient of variation were described and by SAS 6.12 statistical software. Results A total of 21 valid questionnaires were recovered in the first round and 23 valid questionnaires in the second round. The active coefficient of the experts was 84% and 92%, respectively. The results showed that syndromes of newborn heat, damp heat retention, spleen deficiency and blood dryness, wind dampness accumulating skin, blood deficiency and wind dryness demonstrated high concensus. The consistency scores' mean of 5 syndromes were 1.67, 1.90, 1.83, 1.71 and 1.90. The sum of degrees of 5 syndromes were 37, 40, 42, 36 and 40. The ratio of full scores of 5 syndromes were 0.81, 0.90, 0.87, 0.71 and 0.90. The coefficient of variations of 5 syndromes were 0.32, 0.16, 0.27, 0.27 and 0.16. The therapy of syndrome of newborn heat was clearing away the heart-fire and inducing diuresis by the sanxin daochi decoction; The therapy of syndrome of damp heat retention was clearing heat and removing dampness by longdan xiegan decoction; The therapy of syndrome of wind dampness accumulating skin was dispelling wind and eliminating dampness by xiaofeng san; The therapy of syndrome of spleen deficiency and blood dryness was enriching blood and moistening dryness by danggui decoction; The therapy of syndrome of blood deficiency and wind dryness was replenishing qi to invigorate the spleen and enriching blood to calm endogenous wind by shenling baizhu power and danggui decoction. Conclusion Questionnaire survey could quantify the opinions of experts, and provide reference for the establishment of guideline for the diagnosis and treatment of traditional Chinese medicine in the wind of four fossae. Key words: Dermatitis, atopic; The wind of four fossae; Delphi method; Therapeutic methods; Guidebooks

罐疗的历史发展与临床应用

拔罐疗法作为中医的治疗方法在我国源远流长。罐具的革新及应用的普及经历了从古至今的演变。围绕其作用机制，拔罐疗法在临床的应用日益广泛，以其操作简便、安全有效等特点被称为绿色疗法。罐疗成为国内外中医诊疗的重要组成部分，其发展和革新仍在继续。 Cupping therapy for the treatment of traditional Chinese medicine has a long history in China. The innovation and the application popularity of tanks experience the evolution in all ages. Around its action mechanism, cupping therapy is more and more widely used in the clinical application. With its characteristics of simple to operate, safe and effective, it is known as the green therapy. It also becomes an important part of TCM diagnosis and treatment at home and abroad. Its development and innovation continue.

Takotsubo cardiomyopathy in aneurysmal subarachnoid hemorrhage: Institutional experience and literature review

ObjectivesTo review the current practice in the diagnosis, monitoring and management of TCM in SAH patients at our tertiary referral institution and the relevant literature, and to evaluate the effect of certain treatment modalities on the outcome of those patients. Patients and methodsA retrospective institutional chart review of 800 patients with aneurysmal SAH from 2007 to 2014. Eighteen patients were identified to have both aneurysmal SAH and TCM based on echocardiogram. Demographic data, clinical parameters, radiographic findings, treatment modalities, and laboratory results were analyzed. ResultsThe incidence of typical TCM in our patients was 2.2%. Mortality rate of TCM in SAH was 22% compared to the total mortality rate of all non-traumatic SAH patients of 15% in our institution over the same time period. Use of beta blockers prior to or after the diagnosis of TCM did not seem to affect their outcome. Majority of patients (61%) were on vasopressors prior to the diagnosis of TCM. Of those, 73% had good outcomes. Even after the diagnosis of TCM, good outcomes were observed in 6 of 7 patients who remained on vasopressors. ConclusionDespite the general agreement on the importance of the avoidance of vasopressors in TCM, our experience showed that the use of vasopressors is safe in these patients. The use of beta blockers in our patients was not associated with significantly better outcomes despite multiple previous reports on beta blocker usage in TCM.

Food Therapy for the Traditional Chinese Medicine (Tcm) Diagnosis of Dampness

Food Therapy for the Traditional Chinese Medicine (Tcm) Diagnosis of Dampness

Mining analysis and experience summary for chronic atrophic gastritis cases treated by Professor LIU Feng-bin

To summarize Professor LIU Feng-bin's clinical experience and theoretical thoughts on chronic atrophic gastritis (CAG), the study group designed a retrospective study on his case series and expert interview. First of all, the data of CAG patients treated in the First Affiliated Hospital of Guangzhou University of Chinese Medicine between 2009 and 2013, e. g. herbs, diseases, syndrome type, prescription amount and number of herbs, was collected and processed. The statistical description and binary logistic regression were used to determined the syndrome type, initial basic remedy and modification. During the statistics, a complete and sub-group analysis was performed simultaneously. After the expert interview, the syndrome type and medication were finalized. As a result, a total of 228 CAG patients aged at (50.30 ± 10.18) were collected, including 151 males (66.23%). Of them, the TCM diagnosis and syndrome type were extracted from the information of 157 patients, including 115 cases with gastric stuffiness, 23 cases with gastric pain, 19 missing cases, 2 cases with spleen-stomach weakness syndrome, 57 cases with spleen deficiency and dampness-heat syndrome, 18 cases with spleen-stomach disharmony syndrome, 23 cases with syndrome of liver depression syndrome, 21 cases with liver qi invading stomach syndrome and 26 qi and yin deficiency syndrome, respectively. All of the 228 patients used totally 104 herbs, while the subgroups with 157 patients used 94 herbs. The most frequently used 15 herbs used in each groups were analyzed to determine the initial basic remedy and modification. Subsequently, based on the information of the sub-groups with 157 patients, with the syndrome type as the dependent variable, the logistic regression analysis was made on the most frequently used 32 herbs, in order to determined the modification in herbs for different syndrome types. After experts reviewed and modified, they believed the main causes of CAG were dietary irregularities, moodiness and weak constitution; the pathogenesis of CAG was spleen deficiency with qi stagnation, heat depression and blood stasis in the stomach meridian. The above six syndrome types and 12 herbs were determined, including Pseudostellariae Radix, Poria, Atractylodismacrocephalae Rhizoma, Glycyrrhizae Radix et Rhizoma, Fritillariae Thunbergii Bulbus, Sepiae Endoconcha, Arecae Pericarpium, Aurantii Fructus, Perillae Caulis, Herba Hedyotis Diffusae, Scutellariae Barbatae Herba, Curcumae Rhizoma. This study summarized Professor LIU Feng-bin's clinical experience and theoretical thoughts of chronic atrophic gastritis based on clinical practice data and expert interview, with a rigorous design and good scientificity and practicability.

Improving Inter-Rater Reliability of TCM Diagnosis Through the Use of Biomarkers and Other Methods

The Journal of Alternative and Complementary MedicineVol. 20, No. 5 Clinical ResearchImproving Inter-Rater Reliability of TCM Diagnosis Through the Use of Biomarkers and Other MethodsSuzanne Grant and Dennis ChangSuzanne GrantSearch for more papers by this author and Dennis ChangSearch for more papers by this authorPublished Online:7 May 2014https://doi.org/10.1089/acm.2014.5104.abstractAboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View article"Improving Inter-Rater Reliability of TCM Diagnosis Through the Use of Biomarkers and Other Methods." The Journal of Alternative and Complementary Medicine, 20(5), p. A41FiguresReferencesRelatedDetails Volume 20Issue 5May 2014 InformationCopyright 2014, Mary Ann Liebert, Inc.To cite this article:Suzanne Grant and Dennis Chang.Improving Inter-Rater Reliability of TCM Diagnosis Through the Use of Biomarkers and Other Methods.The Journal of Alternative and Complementary Medicine.May 2014.A41-A41.http://doi.org/10.1089/acm.2014.5104.abstractPublished in Volume: 20 Issue 5: May 7, 2014PDF download

Study on quality of life of asymptomatic HIV infected persons with traditional Chinese medicine

Study on quality of life of asymptomatic HIV infected persons with traditional Chinese medical, which can provide the clinical basis for improving the quality of life. This study applied a randomized, double-blind, and placeb-parallel control designed method to select 1 200 persons in the asymptomatic period of HIV infection as the subjects. The subjects were randomly divided into the treatment group and the control group at the ratio of about 2:1. According to the results of monthly differential diagnosis of TCM, the test group and the control group were given homologue Chinese drugs preparations and model Chinese drugs. The total study period was 18 months. Using PRO scale and the world health organization AIDS determination of quality of life short scale form (WHOQOL-HIV-BREF) to investigate asymptomatic HIV infected persons, according to different times, we calculated the total score and each domain score of quality of life of the treatment group and control group, we did statistical analysis. Form the PRO scale,we can see that the treatment group showed a trend of stability, compared with the control group with significant statistical difference (P < 0.05) after 6 months; from the WHOQOL-HIV scale analysis, we can see that compared with before treatment, the quality of life of the treatment group was increased, the difference was significant (P < 0.05), but the quality of life of the control quality of life was decreased, the differences was significant (P < 0.05). Dialectical therapy of Chinese medicine can significantly improve the patient's quality of life, which can provide the basis for the prevention and control policy formulation and implementation with asymptomatic HIV infected persons.

Traditional Chinese Medicine diagnoses in persons with ketamine abuse

ObjectivesTo explore the distribution of TCM patterns in ketamine users and the inter-rater reliability of TCM diagnosis among TCM practitioners. MethodsEighty-four subjects recruited from substance abuse clinics and non-governmental counseling services catering for ketamine abusers were examined by one or two TCM practitioners. The distribution and inter-rater reliability of the TCM diagnoses between the two TCM practitioners were described and measured. ResultsSeven TCM patterns were differentiated. The four most common patterns were the Heart Yin deficiency (29.8%), Kidney Yang deficiency (26.2%), Kidney Yin deficiency (19.0%), and Spleen Yang deficiency (14.3%). The agreement between the two TCM practitioners was 59%; the kappa for the three most common patterns was 0.472 (P=0.003). The proportion of men was lower in the Kidney Yin deficiency group (18.8%), in comparison to the Heart Yin deficiency (60.0%, P=0.009) and Kidney Yang deficiency group (59.1%, P=0.013). ConclusionThe differences between the TCM groups in terms of the source of referral and number of drug uses other than ketamine were of borderline significance. Further research should focus on validating diagnostic tools and improving inter-rater reliability in TCM to enhance the quality of clinical trials of TCM treatments for ketamine abuse.

Mid-ventricular takotsubo: A case report

Introduction: Is mid-ventricular takotsubo really a variant? takotsubo cardiomyopathy (tcM) most commonly presents with both midventricular and apical segment hypokinesia. Less frequently, the apical segment is spared and this variant has been termed mid-ventricular takotsubo. case report: We present a case of a 66-year-old female with chest pressure and abnormal electrocardiography and positive troponin. recently her mother was placed in hospice. Echocardiogram showed severe systolic dysfunction. she underwent left heart catheterization which included left ventriculogram that showed normal coronaries and basilar and apical hyperkinesis and midventricular hypokinesia suggestive of mid ventricular takotsubo. conclusion: We suggest that takotsubo cardiomyopathy (tcM) can be thought of as a continuum in which the midventricular segment is hypokinetic first and then the apical portion becomes hypokinetic later. Moreover, mid-ventricular hypokinesia is a key to a diagnosis of tcM; regardless of the presence of apical dyskinesia. the tcM merely presents in different ways and that the mid-ventricular variant is not a different disease entity from typical tcM.

Exploring the Impact on the TCM Medical Record Connotation Quality of Assessment of TCM Diagnosis and Treatment Plan

AbstractObjective. To explore the impact of assessment of TCM diagnosis and treatment plan on the connotation of TCM medical record. Method. A total of 40 hospitalized patients are divided into groups in accordance with written assessment of TCM treatment. The disease course content is examined by experts and the content of TCM, ideas of diagnosis and treatment, principle and herbs, and the writing format are scored. Then, the scores of the two groups are compared, and the impact on medical record connotation of the evaluation method is analyzed. Result. After the assessment, the total medical record score (155.63 ± 8.18) and scores of content about TCM, ideas of diagnosis and treatment, principle and herbs (41.00 ± 4.47, 40.25 ± 3.88, 40.00 ± 4.73) are found to be higher than those in the control group (140.00 ± 11.18, 34.63 ± 4.08, 35.75 ± 5.14, 32.88 ± 4.39). Conclusion. The assessment methods of TCM treatment can promote understanding and thinking of the physician on the case, and also improve the qua...

A Study on the Correlativity of MRI Signal Classifications with TCM Syndromes in Femoral Head Necrosis Patients

To probe into the relation between magnetic resonance imaging (MRI) signal classifications and TCM syndromes in femoral head necrosis patients, so as to provide reference for TCM diagnosis of this disease. Refering to the criteria for TCM syndrome types of necrosis of the femoral head described in "The Guiding Principles of Clinical Studies of New Chinese Drugs" and Shimizu and Mitchell's MRI signal classifications, MRI signal classifications between different TCM syndrome types were compared. The Shimizu signal classification of different TCM syndrome types had statistically significant difference (P = 0.04); Both T2WI+fs and Mitchell signal classifications of different TCM syndrome types had no statistical by significant differences (P = 0.42 or P = 0.15). There is a certain correlativity of TCM syndrome types of necrosis of the femoral head with T1WI signal classification of MRI. MRI signal classification may contribute to objectivity in TCM syndrome typing of this disease.

Research Thinking of Low-intensity laser For the Treatment of Menopausal Syndrome

Female climacteric syndrome is a clinical syndrome due to autonomic nerve dysfunction occurring in women during climacteric period, which may affect their physical and mental health. Therefore, how to pass climacteric period for women without any problems, avoid or reduce the occurrence of climacteric syndrome, prevent geriatric diseases and improve life quality is a key issue now for great attention. Looking for a convenient, effective, and safer method without toxic-side effects to control the disease is a modern medical problem. By analyzing the relationship between laser technology and traditional acupuncture and moxibustion, the advantage and the existing problems on acupuncture and moxibustion for the treatment of menopausal syndrome, the application of laser methods for the mechanism research on TCM diagnosis and treatment of menopausal syndrome was discussed. It's pointed out that the laser acupuncture is safe and effective to treat menopausal syndrome. Breakthrough will be achieved from the research of the selection of the acupoint prescription and mechanism of Acupuncture and Moxibustion for the treatment of menopausal syndrome by utilizing the advantage of interdisciplinary intersection. Laser technology will make the development of acupuncture and moxibustion science possess an unprecedented field.

Study on Digitization of TCM Diagnosis Applied Extraction Method of Blood Vessel

This paper presents a study on digitization of Traditional Chinese Medicine diagnosis. The research consists of two aspects: a) algorithms for blood vessels extraction in sclera-conjunctiva images, which can be applied in syndrome differentiation by observing human eyes (named Ocular Diagnostic in Traditional Chinese Medicine); b) digitization of extracted vessels. First, sclera-conjunctiva region is isolated by optimal threshold segmentation and mathematical operation; Scanning and edge detection methods are used to gain the edge of the blood vessels. Moreover, the edge feature parameters are gained, which can be used to reconstruct the blood vessels. Experimental results show that blood vessels information can be obtained fast and accurately for the further TCM diagnosis by artificial system.

“Broken heart” after cesarean delivery. Case report and review of literature

To present a rare case of a multiparous woman undergoing elective cesarean section with apparent symptoms of acute coronary syndrome and who was later diagnosed with Takotsubo cardiomyopathy (TCM; "broken heart syndrome"). To review similar case reports already reported in literature. Literature search on the occurrence of TCM in pregnancy using MEDLINE and Cochrane databases. TCM might occur in women with no known pre-existing cardiomyopathy and uncomplicated pregnancies undergoing cesarean section, especially in combination with the administration of catecholamines/vasoconstrictive substances and possibly also oxytocin and prostaglandins. Since TCM is related to emotional and physical stress, the surroundings during cesarean section should be kept quiet and smooth. Adrenergic stimulants (adrenaline, phenylephrine, ergonovine, ephedrine) and anticholinergics (atropine) should be used with caution and adequate volume substitution prior to the onset of spinal analgesia for the prevention of hypotension should be provided. If signs of an acute coronary syndrome during cesarean section do occur, echocardiography is obligatory for diagnosis of TCM.

Tongue diagnosis in the treatment of patients with schizophrenia: Differentiation of patterns and ideas for future research

In TCM, the diagnostic process consists of inspection, auscultation and olfaction, inquiry and palpation. Part of this diagnostic process is the study of the tongue. After careful consideration of all diagnostic information, the treatment points are chosen. During a research project on TCM treatment (weekly treatment for 12 weeks) in patients with chronic schizophrenia, tongue pictures were used in order to monitor treatment progress according to TCM principles. After pre-testing, 12 weeks of treatment, and post-testing; patients were shown their own results on the pre- and post-tests, as well as their own 12 tongue pictures. At that point, tongue pictures turned out to be a great motivation for patients to evaluate their own treatment, to see with their own eyes what changes were, or were not, reached. Moreover, patients concluded that they can personally take an influence in their condition and life, for instance by changing their lifestyles. Many patients reported that, in contrast to their usual antipsychotic medicinal treatment which is evaluated by their psychiatrist and other caretakers, they could really relate to this method of diagnosis and they indicated the willingness to watch their own tongues and work with that. In a group of patients in which treatment compliance is always an issue, this is an important finding. Since all patients in this study suffered from schizophrenia, but not all patients suffered from the same TCM diagnosis, a comparison was made between the patients, according to their tongue diagnosis and tongue pictures in order to come to several subgroups within TCM that might be treated by similar methods. The differentiation of patterns will be presented along with ideas for future research and treatment in this group of chronic patients.