This research endeavors to address the pressing need for nurturing creative thinking skills among primary school students in the context of Mahasarakham province, Thailand. By systematically analyzing the specific challenges and requirements faced by educators, a comprehensive model for enhancing creative thinking skills was developed. This model integrates multidisciplinary methods, hands-on realistic tasks, and combines STEAM (Science, Technology, Engineering, Arts, and Mathematics) education with the 6E technique. The study demonstrates the model's effectiveness in significantly improving creative thinking skills among students. The key findings underscore the value of multidisciplinary approaches, emphasizing experiential learning through practical tasks that stimulate creativity. The fusion of STEAM education and the 6E technique proved to be particularly impactful, aligning with prior research in the field. The research contributes vital insights and practical recommendations for educators and policymakers, urging them to consider multidisciplinary methods, STEAM education, and the 6E technique as viable strategies to bolster creative thinking skills in primary school students.