Target Age Group Research Articles

РЕКРЕАЦИОННО-ОБРАЗОВАТЕЛЬНЫЙ ПОТЕНЦИАЛ ДЕЯТЕЛЬНОСТИ ЧАСТНЫХ МУЗЕЕВ Г. БАРНАУЛА

The paper considers current forms of recreational and educational activities of private museums operating in Barnaul (Altai Krai, Russia). A total number of local private museums is given, dynamics of their development is described and a role played by them in urban social and cultural space at the present day is characterized. Urban population’s target age groups covered by museum work are named. The paper points out on factors affecting the choice and testing forms of contact with visitors applied by Barnaul private museums. Technologies used by such institutions in working with children are analyzed. The authors give examples of multifunctional and complex forms of interaction with museum audience that have influence on recreational, information and educational component of museum communication. Also, trends and problems of development of Barnaul private museums in leisure and recreation organization sector these days are defined.

Forensic medical diagnostics of age by the Cameriere method

Was to conduct the comparative analysis of the age groups' separation accuracy (<18 years old; ≥18 years old) by orthopantomogram depending on the examination's side in Russian population sample. The number of orthopantomograms equal 600 (190 of male and 410 of female) aged from 14 to 23 were investigated. Index value of third molar (Im3) was calculated by the R. Cameriere method, in female and male, on the right and left sides. Index of third molar on the right and left sides shows a high correlation. In the male sample the result specificity was 0.97 on the left and 1.0 on the right, the sensitivity was 0.96 on the left and 0.94 on the right. In the female sample the values were as follows: the specificity was 0.96 on the left and 0.98 on the right, the sensitivity was 0.92 on the left and 0.94 on the right. The results showed the possibility of Im3 (0.08) use to determine the target age group for Russian citizens of both sexes regardless of examination side.

Exploring English Language Development Assessment for Real-Time Interaction between Autonomous Robots and Children: A Preliminary Study

Despite attention by educators and researchers to the advancement of robotics research in education, little experimental research has been conducted on the use of robots in language education for young children. This paper reports on a study aimed at providing an improved English language development assessment questionnaire specifically for use in a project to bring autonomous social robots into English as a foreign language (EFL) classes for native-Korean-speaking children aged 3-5 years old. In order to examine the validity of questionnaire items, a focus group of 10 professors with expertise in child EFL learning was sent the questionnaire, which includes 127 items to be rated on a 5-point Likert scale and two open-ended questions. They were asked to judge whether each item was appropriate for children of the target age group, and whether any items were not appropriate to assess child L2 learners’ English language development. The findings inform the selection of appropriate items for evaluating language development stages based on children’s speaking performance in a robot-assisted language learning condition. The study’s results provide a baseline for an English language assessment questionnaire for EFL teachers to evaluate 3-5-year-old children’s language development in English speaking in the robot-assisted language learning (RALL) condition.

Designing mathematical tasks to enhance financial literacy among children in Grades 1–8

ABSTRACT One approach to incorporating financial literacy into educational curricula is the integration of it into closely related courses such as mathematics. Research on curriculum development that fosters the integration of mathematics and financial literacy is necessary. This study aims to develop mathematical tasks that are embedded with financial literacy concepts to be integrated into mathematics courses. The tasks were designed for children in Grades 1 through 8. They were shaped by considering mathematical education standards, concepts, subjects and objectives. The tasks also addressed related societal issues including fair wages and working conditions. The dynamics that shape the design of the tasks include the interrelationship between mathematics education and financial literacy, children's (as the target age group) financial understanding and task design parameters. Each task, on the one hand, contains the first page geared toward students; on the other, it presents the implementation steps, teaching guidelines, cautions and limitations for teachers as well as background served as the inspiration for the task design. It is expected that the tasks will contribute to the development of students from an early age in financial literacy education as well as be beneficial for relevant experimental studies.

The Impact of Hearing Preservation Education on the Young Adults’ Listening Behavior

Background and Aim: High-level sounds in recreational activities are known as one of the leading causes of developing noise-induced hearing loss, particularly in adolescents and young adults. Thus, this study aimed to explore the practicality of a hearing preservation education program in modifying listening behaviors concerning recreational noise exposure and Personal Listening Device (PLD) use in adolescents and young adults. Methods: Two hundred students, both male and female (n=100, each) between 15 and 18 years old were chosen to participate. These students engaged in the hearing preservation education program and filled in pre-education, post-education, and follow-up questionnaires. The questionnaire assessed the students’ awareness, intention, attitudes, and motivation concerning recreational noise exposure and safe PLD usage. The materials were prepared by an expert panel of audiologists and then remarked as comprehensible by teachers of the target age group. Results: There were significant differences in preferred volume levels and preferred listening levels of PLD, as well as the duration of PLD usage among pre-education, post-education, and follow-up questionnaire measurements (p&lt;0.001). Notably, education significantly altered the students’ awareness, intention, attitudes, and motivation concerning recreational noise exposure among the three experimental conditions (p&lt;0.001). Conclusion: Providing a fundamental guide and effective education to adolescents and young adults will help them to use PLD safely, expand their awareness and knowledge, and consequently revise their attitudes and listening behaviors. Keywords: Noise-induced hearing loss; personal listening device; recreational noise; hearing preservation; young adult and adolescent

Gender differences in the determinants of mature entrepreneurship? The case of Germany.

Mature female entrepreneurs represent a non-traditional model of self-employed workers in both ways: in terms of gender and age. The transition into self-employment for women aged 45 years and older represents a topic of aging research that still tends to be overlooked. Previous studies found ambivalent results for the issue regarding motives and entrepreneurial pathways between former employmen or unemployment-and starting one's own business and the ways in which these entrepreneurial activities are shaped by social differences (such as gender) and biographically accumulated resources and restrictions. This article studies biographical-related factors and motivations that determine what is variously referred to as mature entrepreneurship for men and women aged 45 and above. Using data from the German Socio-Economic Panel (SOEP), the descriptive analysis explains the main gender differences among people within the target age group who have taken the step into self-employment. The multivariate analysis interrogates the main determinants that govern any increase in the probability of becoming self-employed after the age of 45 and seeks to identify the main differences between women and men in relation to such determinants. The results show substantial gender-based occupational segregation in entrepreneurship patterns in this age group, with men working longer hours on average than women and enjoying higher average earnings. However, the multivariate analysis shows that the main drivers for mature entrepreneurship are similar for both men and women and that necessity represents an important factor for everyone for starting a business.

Meaning in Life, Death Anxiety, and Spirituality in the Lesbian, Gay, and Bisexual Community: A Scoping Review.

The changes in people's way of life through the years raise questions on how they address existential needs and concerns, particularly those related to life and death and spiritual connections. Through a scoping review, we surveyed studies on meaning in life, death anxiety, and spirituality within the lesbian, gay, and bisexual (LGB) community. We determined the extent to which these variables have been studied among LGB participants. A total of 28 eligible articles were reviewed. Six studies were found about meaning in life, five studies about death anxiety, and 16 studies about spirituality. Results suggest that meaning in life was derived from experiences related to parenthood, couplehood, and work satisfaction. Studies on death anxiety among LGB participants, which date back to the 1980 and 1990s, indicated the need to conduct present studies in this area. The review showed that LGB members distinguished between spirituality and religion, giving them more positive recognition of the former than the latter. The forms of spiritual expression were anchored to religious practices, for some, and other expressions of belief and faith outside the confines of formally established religions. Spiritual expressions generally accorded the LGB members direction and satisfaction in life. Not all segments of the LGB community were represented in the studies. The available studies, dominantly quantitative, centered only on the LGB experience. Target age groups varied across the studies. The review indicates that future studies can work on exploring these existential factors considering the emerging contexts and paradigms. Future research can focus on determining what factors contribute to meaning in life, given the changes in time.

Molecular epidemiology and clinical features of hand, foot and mouth disease requiring hospitalization after the use of enterovirus A71 inactivated vaccine in chengdu, China, 2017-2022: a descriptive study

ABSTRACT Three inactivated enterovirus A71 (EV-A71) vaccines have been widely vaccinated among children in the targeted age group in mainland China since mid-2016. However, comprehensive virological surveillance of hand, foot and mouth disease (HFMD) over multiple years after the use of EV-A71 vaccines has rarely been conducted. Using long-term data extracted from the Public Health and Clinical Center of Chengdu, we described the clinical, aetiological, and epidemiological characteristics of HFMD inpatients after the use of EV-A71 vaccines from 2017 through 2022. A total of 5115 patients were selected for analysis with a male-to-female ratio of 1.63:1 and were mostly under 5 years of age (97.6%). Among these cases, 4.3% presented with severe symptoms, and 4.1% of severe cases experienced significant complications. EV-A71 was no longer the major serotype for laboratory-confirmed HFMD, responsible for 15.6% of severe cases and 1.2% of mild cases. A significant downwards trend of EV-A71 infections was observed after the use of EV-A71 vaccines (P for trend < 0.001). Coxsackievirus A6 was the predominant pathogen, accounting for 63.5% of mild cases and 36.2% of severe cases. Coxsackievirus A10 (CV-A10) and A16 were sporadically detected, and an upwards trend was observed in the proportion of CV-A10 infections. This study provides baseline molecular epidemiology for the evaluation of EV-A71 vaccination impact and potential serotype replacement based on HFMD inpatients. Additional nationwide and population-based epidemiologic and serologic studies are essential to elucidate HFMD dynamics after the use of EV-A71 vaccines, and to inform public health authorities to introduce optimized intervention strategies.

Categorizing older adults' information technology-based learning programs using correspondence analysis

PurposeThe rapid proliferation of digital devices, population aging, and acceleration of digital technology adoption due to the COVID-19 pandemic have increased the need for information education for older adults to prevent inter-generational conflicts and digital alienation. This study aims to analyze the information technology (IT) education programs provided to older adults by age group, considering their heterogeneity.Design/methodology/approachThis study identifies IT education programs provided by public institutions in Seoul and target age groups (50 and above) through a survey using triangulation, which were then sorted and summarized into 27 keywords. Correspondence analysis was conducted using the keywords derived for the programs and age groups.FindingsIT education programs in the age group 60 and above accounted for 75.2% of the programs offered, which increased to 90% when including those aged 55 and above. Particularly, the perceptual map created based on relationship correlations indicates which IT education program keywords matched each age group. The Seoul Metropolitan Government primarily offered these programs for older adults aged 60 and above, with 5–7.5 times more education programs for those aged 60 and above than for those aged 50 and above or 55 and above. Therefore, IT education must be more evenly provided to more diverse age groups among older adults to reflect the current situation.Originality/valueThis study contributes to the literature by proposing a future direction for IT education of older adults. Moreover, it has implications for the direction of IT education to target various age groups in IT education programs, thus enabling older adults to effectively enhance their digital literacy skills during the rapid digitalization caused by COVID-19.

CervicalScreen Norway – A screening programme in transition

An organised screening programme for cervical cancer (CervicalScreen Norway) was implemented in Norway in 1995. The overall aim of the programme is to reduce the incidence and mortality of cervical cancer, and the screening coverage should exceed 80%. Women in the target age group (25-69 years) are invited for screening every third or fifth year depending on whether the primary screening test is a cytology smear or an HPV (human papillomavirus) test. Since the initiation, there have been major changes within the programme and HPV testing has become increasingly important. The primary screening test has changed from cytology for the whole target age group to primary HPV testing for women from the age of 34, HPV genotype information is directing the follow-up of women in the screening algorithm, and HPV self-sampling will be implemented to increase attendance in under-screened women. CervicalScreen Norway has had a significant impact on reducing the incidence and mortality of the disease. Nevertheless, there has been an increase in incidence in Norway the last decade, in particular among young women. In 2018, the WHO Director-General announced an ambitious global call for action to eliminate cervical cancer through vaccination, screening and treatment. CervicalScreen Norway supports the ambition of the WHO and is working towards this goal.

The Effect of Nutrition Educational Programs on the Composition of Home Prepared Children’s Breakfasts

The study aimed to examine the effectiveness of two intervention programs in improving dietary habits in two groups of preschool and fifth-grade students. The programs were tailored to the target age group. The composition of each of the children’s breakfasts that were brought from home was recorded both before and after the intervention program. Every food item received a score according to its nutritional quality, and each meal was summed accordingly. T-tests were performed in order to determine the significance of differences between the nutritional quality of the children’s breakfast items before and after the intervention. It was found that the nutritional quality of all breakfast components and its overall health quality improved significantly in both age groups. The study’s results indicate that the intervention program is effective for a range of young ages. It is recommended to conduct such programs starting in preschools, and subsequently in schools. Keywords: nutrition educational program, health education, meal components

Virology in Schoolbooks—A Comprehensive Analysis of Austrian Biology Textbooks for Secondary School and Implications for Improvement

Virology has gained much attention in recent years due to the COVID-19 pandemic and other recurrent epidemics/pandemics such as Ebola, zika, or now, monkeypox. We have analysed all recent biology schoolbooks for secondary school approved for the Austrian market. Our aim was to find out whether virological content was presented comprehensively, comprehensibly, and in an error-free manner. This also relates to visual representations of viruses, processes related to virology (e.g., replication), and references to daily life. Furthermore, we looked for tasks related to virology that may help students to deepen their newly acquired knowledge and/or to put it into practice, either by hands-on experimentation or transfer tasks. We examined 97 books (76 books for lower secondary and 21 books for upper secondary school). For this analysis, we developed and tested a coding matrix accompanied with a comprehensive coding guide to facilitate reproducible and reliable ratings. Since inter-rater reliability was found to be very high, both the coding matrix and guide can be recommended for further studies in this field. Overall, the virological content provided was free of errors, with the text and illustrations being mostly comprehensive and comprehensible. This was expected, since all Austrian school books must be approved by a governmental commission. However, individual books even for the same target (age) group differed widely in content and detail. In particular, few books clearly differentiated between viruses and bacteria, clarified that viruses are non-living and emphasized that antibiotics are ineffective against viruses. Yet precisely such knowledge is essential to enable students to make scientifically based decisions in health-related situations, especially for the prevention and treatment of viral diseases (e.g., whether to take antibiotics when suffering from a viral disease).

Immunogenicity and safety of one-dose human papillomavirus vaccine compared with two or three doses in Tanzanian girls (DoRIS): an open-label, randomised, non-inferiority trial

An estimated 15% of girls aged 9-14 years worldwide have been vaccinated against human papillomavirus (HPV) with the recommended two-dose or three-dose schedules. A one-dose HPV vaccine schedule would be simpler and cheaper to deliver. We report immunogenicity and safety results of different doses of two different HPV vaccines in Tanzanian girls. In this open-label, randomised, phase 3, non-inferiority trial, we enrolled healthy schoolgirls aged 9-14 years from Government schools in Mwanza, Tanzania. Eligible participants were randomly assigned to receive one, two, or three doses of either the 2-valent vaccine (Cervarix, GSK Biologicals, Rixensart) or the 9-valent vaccine (Gardasil-9, Sanofi Pasteur MSD, Lyon). The primary outcome was HPV 16 specific or HPV 18 specific seropositivity following one dose compared with two or three doses of the same HPV vaccine 24 months after vaccination. Safety was assessed as solicited adverse events up to 30 days after each dose and unsolicited adverse events up to 24 months after vaccination or to last study visit. The primary outcome was done in the per-protocol population, and safety was analysed in the total vaccinated population. This study was registered in ClinicalTrials.gov, NCT02834637. Between Feb 23, 2017, and Jan 6, 2018, we screened 1002 girls for eligibility. 72 girls were excluded. 930 girls were enrolled and randomly assigned to receive one dose of Cervarix (155 participants), two doses of Cervarix (155 participants), three doses of Cervarix (155 participants), one dose of Gardasil-9 (155 participants), two doses of Gardasil-9 (155 participants), or three doses of Gardasil-9 (155 participants). 922 participants received all scheduled doses within the defined window (three withdrew, one was lost to follow-up, and one died before completion; two received their 6-month doses early, and one received the wrong valent vaccine in error; all 930 participants were included in the total vaccinated cohort). Retention at 24 months was 918 (99%) of 930 participants. In the according-to-protocol cohort, at 24 months, 99% of participants who received one dose of either HPV vaccine were seropositive for HPV 16 IgG antibodies, compared with 100% of participants who received two doses, and 100% of participants who received three doses. This met the prespecified non-inferiority criteria. Anti-HPV 18 seropositivity at 24 months did not meet non-inferiority criteria for one dose compared to two doses or three doses for either vaccine, although more than 98% of girls in all groups had HPV 18 antibodies. 53 serious adverse events (SAEs) were experienced by 42 (4·5%) of 930 girls, the most common of which was hospital admission for malaria. One girl died of malaria. Number of events was similar between groups and no SAEs were considered related to vaccination. A single dose of the 2-valent or 9-valent HPV vaccine in girls aged 9-14 years induced robust immune responses up to 24 months, suggesting that this reduced dose regimen could be suitable for prevention of HPV infection among girls in the target age group for vaccination. UK Department for International Development/UK Medical Research Council/Wellcome Trust Joint Global Health Trials Scheme, The Bill & Melinda Gates Foundation, and the US National Cancer Institute. For the KiSwahili translation of the abstract see Supplementary Materials section.

Study profile: oral health assessment among participants of “Epidemiology of cardiovascular diseases in Russian regions. Third study” in the Arkhangelsk region

RATIONALE AND AIMS: The population of North Russia has a high prevalence of both cardiovascular and dental diseases. The Arkhangelsk region was included in the third phase of the multicenter study entitled Epidemiology of cardiovascular diseases in Russian regions. Third study (ESSE-RF3). The ESSE-RF3 study studied the prevalence of cardiovascular diseases, their biological and behavioral risk factors, and the associations with regional economic, climatic, and geographical characteristics. The Arkhangelsk part of the study is unique as it involved an assessment of the oral health of the ESSE-RF3 study participants. The oral health study protocol is presented in this paper.&#x0D; METHODS: A population-based study was performed from February 24 through June 30 in the year 2021 at the outpatient facility of the Northern State Medical University in Arkhangelsk. A representative sample of 1816 permanent residents of the Arkhangelsk region aged 3574 years participated in the ESSE-RF3 study. Most of them (84.987.5%) agreed to take part in the oral phase of the study, which included the use of a questionnaire, the collection of oral and gingival crevicular fluid, assessment of dental and periodontal health status using a WHO (2013) methodology; oral hygiene and dental aesthetic index; an orthodontic assessment with periotestometry and a photo protocol. In addition, an in-depth orthodontic study was performed on a sub-sample of the participants aged 3551 years (n=236) using teleroentgenography, cone-beam computed tomography, and biometrics of the plaster models.&#x0D; EXPECTED RESULTS AND CONCLUSIONS: The study will assess the prevalence of a wide range of states and conditions related to oral health in a representative sample of the adult population of the Arkhangelsk region in the target age-group using validated international instruments to ensure comparability and reproducibility of the findings. More importantly, the study will assess the associations between various aspects of oral health and cardiovascular diseases, their risk factors as well as regional and behavioral characteristics studied by the main ESSE-RF3 study protocol.

Google Trends on Human Papillomavirus Vaccine Searches in the United States From 2010 to 2021: Infodemiology Study

BackgroundThe human papillomavirus (HPV) vaccine is recommended for adolescents and young adults to prevent HPV-related cancers and genital warts. However, HPV vaccine uptake among the target age groups is suboptimal.ObjectiveThe aim of this infodemiology study was to examine public online searches in the United States related to the HPV vaccine from January 2010 to December 2021.MethodsGoogle Trends (GT) was used to explore online searches related to the HPV vaccine from January 1, 2010, to December 31, 2021. Online searches and queries on the HPV vaccine were investigated using relative search volumes (RSVs). Analysis of variance was performed to investigate quarterly differences in HPV vaccine searches in each year from 2010 to 2021. A joinpoint regression was used to identify statistically significant changes over time; the α level was set to .05.ResultsThe year-wise online search volume related to the HPV vaccine increased from 2010 to 2021, often following federal changes related to vaccine administration. Joinpoint regression analysis showed that HPV vaccine searches significantly increased on average by 8.6% (95% CI 5.9%-11.4%) across each year from 2010 to 2021. Moreover, HPV vaccine searches demonstrated a similar pattern across years, with search interest increasing through August nearly every year. At the state level, the highest 12-year mean RSV was observed in California (59.9, SD 14.3) and the lowest was observed in Wyoming (17.4, SD 8.5) during the period of 2010-2021.ConclusionsOnline searches related to the HPV vaccine increased by an average of 8.6% across each year from 2010 to 2021, with noticeable spikes corresponding to key changes in vaccine recommendations. We identified patterns across years and differences at the state level in the online search interest related to the HPV vaccine. Public health organizations can use GT as a tool to characterize the public interest in and promote the HPV vaccine in the United States.

Game criticality in male youth football: Situational and age-related effects on the goal-scoring period in Portuguese national championships

Abstract. Research crossing the effects of situational variables with the temporal analysis of goals scored in football is scarce, particularly in youth football. Hence, the present study aimed to (1) analyse the effects of match location, match status, team quality, goal criticality, and age group on match periods in which goals are scored in male youth football, and (2) examine whether the age group (U17, U19, and U23) influences the emergence of critical moments in matches from the Portuguese national championships. The sample consisted of 2,591 goals scored in the U17, U19, and U23 Portuguese national championships during the 2019/2020 season. Chi-square tests revealed that match location, match status, goal criticality, and age group were significantly associated with the goal-scoring period. During the first halves, more goals were scored (1) when playing at home, (2) when teams were tied or losing by one goal (critical circumstances) and (3) by U17 teams. A multinomial logistic regression model revealed that the chances of scoring in the sixth period (vs the first) significantly decreased when playing at home, and in U17 and U19 matches. The U23 teams were more likely to score in the last period regardless of goal criticality. However, the interaction effect of team quality x age group suggests that U17 and U19 teams are more prone to score in later match periods when team ability is equated. These findings enable coaches to improve the tactical, physical, and psychological preparation for competitive youth matches depending on the target age group. Keywords: goal, critical moments, contextual variables, temporal analysis, soccer.

Problems with catch-up HPV vaccination after resumption of proactive recommendations.

We previously reported that the suspension of the proactive recommendation for human papillomavirus (HPV) vaccination in Japan led to an increase in infection rates and incidence of cytological abnormalities, 1 Sekine M Yamaguchi M Kudo R et al. Suspension of proactive recommendations for HPV vaccination has led to a significant increase in HPV infection rates in young Japanese women: real-world data. Lancet Reg Health West Pac. 2021; 16100300 PubMed Google Scholar , 2 Yagi A Ueda Y Ikeda S et al. The looming health hazard: a wave of HPV-related cancers in Japan is becoming a reality due to the continued suspension of the governmental recommendation of HPV vaccine. Lancet Reg Health West Pac. 2022; 18100327 PubMed Google Scholar and appealed for proactive recommendations to be reinstated. 3 Ueda Y Yagi A Ikeda S Enomoto T Kimura T Beyond resumption of the Japanese government's recommendation of the HPV vaccine. Lancet Oncol. 2018; 19: 1563-1564 Summary Full Text Full Text PDF PubMed Scopus (15) Google Scholar In response to our findings, the Japanese Ministry of Health, Labour, and Welfare resumed proactive recommendations for the HPV vaccine in April, 2022, and initiated catch-up vaccinations for women who might have missed the opportunity to receive the vaccine during the period when proactive recommendations were suspended. 4 Haruyama R Obara H Fujita N Japan resumes active recommendations of HPV vaccine after 8·5 years of suspension. Lancet Oncol. 2022; 23: 197-198 Summary Full Text Full Text PDF PubMed Scopus (7) Google Scholar A large proportion of women in the target age group (17–25 years) in Japan's fiscal year 2022 will be eligible for the recommended catch-up vaccination (figure). 5 Nakagawa S Ueda Y Yagi A Ikeda S Hiramatsu K Kimura T Corrected human papillomavirus vaccination rates for each birth fiscal year in Japan. Cancer Sci. 2020; 111: 2156-2162 Crossref PubMed Scopus (24) Google Scholar To reduce the incidence of invasive cervical cancer in Japan, a catch-up vaccination programme with at least 50% coverage will be required. 6 Simms KT Hanley SJB Smith MA Keane A Canfell K Impact of HPV vaccine hesitancy on cervical cancer in Japan: a modelling study. Lancet Public Health. 2020; 5: e223-e234 Summary Full Text Full Text PDF PubMed Scopus (89) Google Scholar To date, England, Sweden, Denmark, and the USA have successfully implemented national catch-up HPV vaccination programmes. In these countries, catch-up vaccination has been reported to have substantially reduced the incidence of cervical precancer and invasive cancer. However, in England, low vaccination coverage among the catch-up generation has been reported. Coverage of three doses of the HPV vaccine was high for women who received the routine vaccination at age 12–13 years (80·9–88·0%), but lower for the catch-up cohorts (70·8–75·7% for age 14–16 years, and 38·9–48·1% for age 16–18 years). 7 Falcaro M Castañon A Ndlela B et al. The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: a register-based observational study. Lancet. 2021; 398: 2084-2092 Summary Full Text Full Text PDF PubMed Scopus (116) Google Scholar Catch-up vaccination is challenging in Japan because no national HPV vaccine register exists, and immunisation histories are maintained individually by each municipality (approximately 1700) that has provided routine vaccinations. 8 Yamaguchi M Sekine M Kudo R et al. Differential misclassification between self-reported status and official HPV vaccination records in Japan: implications for evaluating vaccine safety and effectiveness. Papillomavirus Res. 2018; 6: 6-10 Crossref PubMed Scopus (26) Google Scholar For example, if a woman who received the HPV vaccination at age 12–16 years in one municipality moves to a residential address in another municipality, it would not be possible to ascertain her vaccination history from the previous municipality. Thus, a woman who has received three doses of the HPV vaccine in one municipality would be advised to receive three more doses of the HPV vaccine if she moved to another municipality. Thus, the vaccination programme will rely on patient recall regarding personal vaccination history. In our previous study, 1230 women aged 20–22 years between fiscal year 2014 and fiscal year 2017 were asked in a questionnaire whether they had been vaccinated in the past. 140/308 (45·5%) of those who responded that they had not been vaccinated had received 1–3 doses of the vaccine. 8 Yamaguchi M Sekine M Kudo R et al. Differential misclassification between self-reported status and official HPV vaccination records in Japan: implications for evaluating vaccine safety and effectiveness. Papillomavirus Res. 2018; 6: 6-10 Crossref PubMed Scopus (26) Google Scholar In our current analysis of 1778 women aged 20–26 years in fiscal year 2020 (appendix), 199/879 (22·6%) of those vaccinated reported that they had never been vaccinated. Recall of women who visited clinics with their parents at age 12–16 years and received the HPV vaccine was poor.

Involvement of Road Users from the Productive Age Group in Traffic Crashes in Saudi Arabia: An Investigative Study Using Statistical and Machine Learning Techniques

Road traffic crashes (RTCs) are a major problem for authorities and governments worldwide. They incur losses of property, human lives, and productivity. The involvement of teenage drivers and road users is alarmingly prevalent in RTCs since traffic injuries unduly impact the working-age group (15–44 years). Therefore, research on young people’s engagement in RTCs is vital due to its relevance and widespread frequency. Thus, this study focused on evaluating the factors that influence the frequency and severity of RTCs involving adolescent road users aged 15 to 44 in fatal and significant injury RTCs in Al-Ahsa, Saudi Arabia. In this study, firstly, descriptive analyses were performed to justify the target age group analysis. Then, prediction models employing logistic regression and CART were created to study the RTC characteristics impacting the target age group participation in RTCs. The most commonly observed types of crashes are vehicle collisions, followed by multiple-vehicle and pedestrian crashes. Despite its low frequency, the study area has a high severity index for RTCs, where 73% of severe RTCs include individuals aged 15 to 44. Crash events with a large number of injured victims and fatalities are more likely to involve people in the target age range, according to logistic regression and CART models. The CART model also suggests that vehicle overturn RTCs involving victims in the target age range are more likely to occur as a result of driver distraction, speeding, not giving way, or rapid turning. As compared with the logistic regression model, the CART model was more convenient and accurate for understanding the trends and predicting the involvement probability of the target age group in RTCs; however, this model requires a higher processing time for its development.

Assessing Vaccination Prioritization Strategies for COVID-19 in South Africa Based on Age-Specific Compartment Model

The vaccines are considered to be important for the prevention and control of coronavirus disease 2019 (COVID-19). However, considering the limited vaccine supply within an extended period of time in many countries where COVID-19 vaccine booster shot are taken and new vaccines are developed to suppress the mutation of virus, designing an effective vaccination strategy is extremely important to reduce the number of deaths and infections. Then, the simulations were implemented to study the relative reduction in morbidity and mortality of vaccine allocation strategies by using the proposed model and actual South Africa's epidemiological data. Our results indicated that in light of South Africa's demographics, vaccinating older age groups (>60 years) largely reduced the cumulative deaths and the “0–20 first” strategy was the most effective way to reduce confirmed cases. In addition, “21–30 first” and “31–40 first” strategies have also had a positive effect. Partial vaccination resulted in lower numbers of infections and deaths under different control measures compared with full vaccination in low-income countries. In addition, we analyzed the sensitivity of daily testing volume and infection rate, which are critical to optimize vaccine allocation. However, comprehensive reduction in infections was mainly affected by the vaccine proportion of the target age group. An increase in the proportion of vaccines given priority to “0–20” groups always had a favorable effect, and the prioritizing vaccine allocation among the “60+” age group with 60% of the total amount of vaccine consistently resulted in the greatest reduction in deaths. Meanwhile, we observed a significant distinction in the effect of COVID-19 vaccine allocation policies under varying priority strategies on relative reductions in the effective reproduction number. Our results could help evaluate to control measures performance and the improvement of vaccine allocation strategy for COVID-19 epidemic.

Characterization of Pediatric Genital Injuries Due to Consumer Products From 2011 to 2020

ObjectiveTo describe demographic trends of consumer product-related injuries in the pediatric cohort from 2011 – 2020. MethodsThe National Electronic Injury Surveillance System (NEISS) database surveying emergency department visits was retrospectively searched for all pediatric genitourinary injuries from 2011 to 2020. Data on demographics, diagnosis, products, disposition, and anatomy injured were collected on patients between the ages of 0-19 years. Statistical analysis was performed using linear regression. ResultsThere were 12,953 reported pediatric cases involving injuries of the genital region from 2011 to 2020 with a national estimate of 324,636 (95% CI 241,527 – 407,746) pediatric genital injuries, comprising 0.76% of total pediatric injuries in the past decade. Of these patients, female (54.2%), white (39.7%) individuals sustained the most injuries, and items most commonly responsible included bicycles (9.4%), playground equipment (6.9%), toilets (4.6%), beds (4.5%), bathtubs and showers (4.4%), soaps (4.4%), chairs (4.1%), and razors and shavers (2.3%). Urethral injuries were due to chemical injuries from soaps (22%), furniture (17%), playground injuries (17%), insertion of foreign bodies into the urethra (13%), bicycles (10%), and swimming related injuries (4%). Genital injuries in children 0-5 years old were primarily caused by furniture (47.8%), while injuries in the 6-10, 11-15, and 16-19 age groups were attributed to sports and recreation (41.2%, 24.6%, 12.2% respectively). There was no significant change in the annual number of pediatric genital injuries from 2011 to 2020 (R2 = 0.38, P = 0.057). ConclusionIdentifying factors involved in pediatric genital trauma can allow for increased legislation, surveillance, and prevention of such injuries in targeted age groups.