Talent Program Research Articles

Effectiveness and safety of community-led assisted partner service among HIV-diagnosed men who have sex with men: a multicentre, randomized controlled trial in China

No randomized controlled trials have involved established HIV-diagnosed men who have sex with men (MSM) diagnosed for more than 6 months into the assisted partner service (aPS). We compared voluntary aPS involving community-based organizations (CBOs) and HIV self-testing (aPSST) with regular partner service (rPS) in HIV-diagnosed MSM irrespective of diagnosis time. In this unblinded, multicentre trial, we enrolled HIV-diagnosed MSM irrespective of diagnosis time in three cities in northern China. Index patients were randomly assigned to aPSST or rPS. Index patients in the aPSST group were additionally provided a comprehensive intervention package including HIV self-testing and CBO-based aPS compared with rPS group. The primary outcome was the number of index patients whose any sexual partner tested for HIV during the 6-month study. Completion of HIV testing was defined as sexual partners taking a clinic-based HIV test or HIV self-testing. Safety was assessed preliminary at the end of the 6-month follow-up. This study has been registered at chictr.org.cn (ChiCTR2000038784). From March to December 2021, 325 of HIV-diagnosed MSM were enrolled (90⋅2% were established HIV-diagnosed MSM) and randomly assigned to receive aPSST (n=167) or rPS (n=158). At 6 months, 110 (65⋅9%) index patients in the aPSST group had at least one sexual partner tested for HIV compared with 50 (31⋅6%) in the rPS group (hazard ratio 2⋅86; 95% confidence interval 2⋅03-4⋅03; p<0⋅001). No significant difference was observed in effects of aPSST on HIV testing promotion between established and newly HIV-diagnosed MSM. Self-reported harms were infrequently observed in both groups (approximately 2⋅0%). Among HIV-diagnosed MSM regardless of diagnosis time, voluntary aPS involving CBOs and HIV self-testing was effective and safe for promoting partner HIV testing. This work was supported by the Mega-Projects of National Science Research, the National Natural Science Foundation of China and the Liaoning Revitalization Talents Program, China.

Lepton flavor violating decays of vector mesons in the MRSSM* *Supported by the Natural Science Foundation of Hebei Province (A2022104001, A2022201017), the Shanxi Scholarship Council of China (2021-31), the youth top-notch talent support program of the Hebei Province, and the Foundation of Baoding University (2018Z01)

In this study, we analyze the rare decays of the neutral vector mesons and in the scenario of the minimal R-symmetric supersymmetric standard model using the effective Lagrangian method. The predicted branching ratios are dominated by the mass insertion parameters , i.e., the off-diagonal inputs, and the contributions of different parts are comparable. Taking into account the experimental constraints on the mass insertion parameters, the predicted branching ratios for the most promising processes are ten orders of magnitude smaller than the present experimental bounds.

China’s technology acquisition for military innovation: spectrum of legality in strategic competition

ABSTRACT The People’s Republic of China’s (PRC) acquires foreign technology to upgrade its military capabilities. We describe how PRC-affiliated actors acquire technology according to a legal, extra-legal, and illegal taxonomy based on laws in the United States and highlight each activity using illustrative examples. Policymakers in advanced industrial countries lack comprehensive data and do not have accurate estimates of the size of the problem for activities such as technology licensing, investing in technology companies, or talent programs. For intellectual property theft, the economic estimates are high but assessing the impact on military innovation remains fraught with measurement errors. Devising appropriate policy responses requires a complete inventory of methods used across the spectrum of legality to decide on technology protection priorities and allocate resources accordingly.

Satellite cell-derived exosome-mediated delivery of microRNA-23a/27a/26a cluster ameliorates renal tubulointerstitial fibrosis in diabetic nephropathy

Objective: Renal tubulointerstitial fibrosis (TIF) is the final convergent pathway of diabetic nephropathy (DN), yet no effective targeted therapies currently can prevent the progression of TIF. Here, as a novel and more effective gene therapy approach, the microRNA (miRNA) clusters provide a method to tackle this issue. Methods: Differentially expressed miRNAs in the serum of DN patients were identified by miRNA sequencing (miRNA-seq). We engineered a kidney targeting exosomes (Exos) vector that contained Lamp2b, an exosomal membrane protein gene fused with rabies virus glycoprotein (RVG) peptide. We transfected this vector into muscle satellite cells and then transduced these cells with adenovirus that expresses miR-23a/27a/26a cluster to manufacture the resultant Exos denoted as RVG-miR-23a/27a/26a-Exos. Db/db mice were injected by tail vein with RVG-miR-23a/27a/26a-Exos and the biodistribution of Exos in db/db mice was imaged by the IVIS. RNA sequencing (RNA-seq) and bioinformatic analysis were performed to explore downstream targets of miRNAs. Results: MiRNA-seq results showed that a total of 23 differentially expressed miRNAs with fold-change &gt;2.0 and p value &lt;0.05 were identified (six downregulated and seventeen upregulated) in serum samples from patients with DN, among which miR-23a, miR-26a, and miR-27a were significantly decreased. Then, it was confirmed that miR-23a, miR-26a and miR-27a expression in the serum of patients with DN were reduced by 47%, 57% and 38%, respectively. Moreover, Pearson's correlation analysis showed that miR-23a, miR-26a and miR-27a had strong negative correlation with TIF and renal function decline. Then, we combined miR-23a, miR-26a and miR-27a as an artificially engineered cluster and successfully engineered RVG-miR-23a/27a/26a cluster loaded exosomes derived from muscle satellite cells, which not only enhanced the stability of miR-23a/27a/26a cluster, but also efficiently delivered more miR-23a/27a/26a cluster homing to injured kidney. More importantly, treatment with RVG-miR-23a/27a/26a-Exos significantly ameliorated tubular injury and TIF in mice with DN. Mechanistically, we showed that miR-23a/27a/26a-Exos could potentiate antifibrotic effects by regulating miRNA cluster-targeting Lpp simultaneously, as well as miR-27a-targeting Zbtb20 and miR-26a-targeting Klhl42, respectively. Conclusions: We established a novel kidney-targeting Exo-based delivery system by manipulating the miRNA-23a/27a/26a cluster to ameliorate TIF in DN effectively, providing a promising therapeutic strategy for DN. This work was supported by the National Natural Science Foundation of China (Nos. 81970664, 82000648, 82070735); the Natural Science Foundation of Jiangsu Province (Nos. BK20211385, BK20200363); the 789 Outstanding Talent Program of SAHNMU (Nos. 789ZYRC202080119, 789ZYRC202090251) and the Science and Technology Development Foundation of Nanjing Medical University (No. NMUB2020049). This is the full abstract presented at the American Physiology Summit 2023 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Oral Azvudine for hospitalised patients with COVID-19 and pre-existing conditions: a retrospective cohort study.

As the COVID-19 pandemic continues to spread, the number of associated deaths continues to increase, especially among those with pre-existing conditions. Azvudine is recommended as a priority treatment for patients with COVID-19, but its efficacy in patients with pre-existing conditions is unknown. This is a single-centre, retrospective cohort study between December 5, 2022 and January 31, 2023 in Xiangya Hospital of Central South University in China to evaluate the clinical efficacy of Azvudine in hospitalised patients with COVID-19 and pre-existing conditions. Patients with Azvudine and controls were propensity score-matched (1:1) for age, gender, vaccination status, time from symptom onset to treatment exposure, severity at admission, concomitant treatments initiated at admission. The primary outcome was a composite outcome of disease progression, and the secondary outcome was each of these individual disease progression outcomes. The univariate Cox regression model was used to estimate a hazard ratio (HR) with 95% confidence interval (CI) for each result between the groups. We identified 2118 hospitalised patients with COVID-19 during the study period, with a follow-up of up to 38 days. After exclusions and propensity score matching, we included 245 Azvudine recipients and 245 matched controls. Azvudine recipients had lower crude incidence rate of composite disease progression outcome compared with matched controls (7.125/1000 person-days vs. 16.004/1000 person-days, P=0.018). There was no significant difference in all-cause death between these two groups (1.934/1000 person-days vs. 4.128/1000 person-days, P=0.159). Azvudine treatment was associated with significantly lower risks of composite disease progression outcome compared with matched controls (HR: 0.49; 95% CI: 0.27-0.89, P=0.016). A significant difference in all-cause death was not found (HR: 0.45; 95% CI: 0.15-1.36, P=0.148). These findings indicate that Azvudine therapy showed substantial clinical benefits in hospitalised patients with COVID-19 and pre-existing conditions, and should be considered for this population of patients. This work was supported by the National Natural Science Foundation of China (Grant Nos. 82103183 to F. Z., 82102803, 82272849 to G. D.), National Natural Science Foundation of Hunan Province (Grant Nos. 2022JJ40767 to F. Z., 2021JJ40976 to G. D.), Huxiang Youth Talent Program (Grant Nos. 2022RC1014 to M.S.) and Ministry of Industry and Information Technology of China (Grant Nos. TC210804V to M.S.).

Proses Pembuatan Roundown dan Que Card Event Darmo Car Free Day (CFD) Di TV9 Nusantara Surabaya

&#x0D; &#x0D; The Darmo Car Free Day (CFD) program is an event program that is held every Sunday by TV9 Nusantara. In realizing the program, the implementation of the program includes three production management processes, namely pre-production, production and post-production. Pre-production includes how to manage the program, starting from making concepts, arranging roundwon events, making queue cards, determining talent programs, arranging cameramen, to determining program speakers, as well as collaborating and looking for sponsors.&#x0D; &#x0D; &#x0D; &#x0D; &#x0D; &#x0D; &#x0D;

PD23-08 N-ACETYLCYSTEINE AMELIORATES HIGH GLUCOSE-INDUCED BLADDER DYSFUNCTION ASSOCIATED WITH METABOLIC SYNDROMES BY MEDIATING MITOCHONDRIAL FUNCTION AND THE ROS/NLRP3/NF-κB SIGNALING PATHWAYS

You have accessJournal of UrologyCME1 Apr 2023PD23-08 N-ACETYLCYSTEINE AMELIORATES HIGH GLUCOSE-INDUCED BLADDER DYSFUNCTION ASSOCIATED WITH METABOLIC SYNDROMES BY MEDIATING MITOCHONDRIAL FUNCTION AND THE ROS/NLRP3/NF-κB SIGNALING PATHWAYS Qiqi He, Junsheng Bao, Panfeng Shang, Li Yang, Zhiping Wang, and Sanjay Gupta Qiqi HeQiqi He More articles by this author , Junsheng BaoJunsheng Bao More articles by this author , Panfeng ShangPanfeng Shang More articles by this author , Li YangLi Yang More articles by this author , Zhiping WangZhiping Wang More articles by this author , and Sanjay GuptaSanjay Gupta More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003296.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: We previously demonstrated that metabolic syndromes contribute to bladder dysfunction by altering the phenotype of bladder smooth muscles. We conducted this study to further examine the potential molecular mechanisms of metabolic syndromes (MS)-mediated bladder dysfunctions to facilitate diagnosis and therapeutic interventions. METHODS: In vitro, bladder muscle cells from C57BL/6N mice were cultured and divided into the control group, HG (45 MM) group, HG (45 MM)+NAC (5 MM) group, and HOS (50 MM) group. Oxidative stress, inflammation and fibrosis levels in BSMCs were observed by qRT‒PCR and Western blot analysis. Functional and morphological changes in mitochondria were examined. In vivo, forty SD rats (6 wks of age) were divided into four groups and bred until twenty weeks: control (CON), High Fat Diet (HFD), HFD+300 mg/kg/d NAC (HFD+LNAC), and HFD+900 mg/kg/d NAC (HFD+HNAC)}. At the end of the 20 weeks, blood and bladder smooth muscle samples were collected, and OS and contractile levels were examined. RESULTS: In vitro, high glucose significantly enhanced oxidative stress, inflammation and fibrosis in BSMCs. Moreover, the increase in cytokine expression was accompanied by enhanced NLRP3 expression and the phosphorylation of NF-κB. However, N-acetylcysteine had an inhibitory effect on the expression of ROS/NLRP3/NF-κB and the dissolution of mitochondria in HG-treated BSMCs. In vivo, compared to those in the control group, the mean contractility and frequency of bladder smooth muscles in the HFD group was significantly decreased (p<0.01). The mean contractility in the LNAC+HFD group was significantly higher than that in the HFD group (p<0.01). Interestingly, the HNAC+HFD group did not show any recovery in muscle contractility but exhibited significantly reduced bladder contractile frequency (p<0.01). CONCLUSIONS: Our findings indicated that high glucose-induced oxidative stress, inflammation and fibrosis are mainly mediated by the ROS/NLRP3/NF-κB signaling pathways and mitochondrial changes in BSMCs. NAC ameliorated these changes by blocking the ROS/NLRP3/NF-κB signaling pathways and protecting mitochondrial function and morphology. Source of Funding: National Natural Science Foundation of China ( 81800671), Cuiyin Talent Program (CY2021-MS-A02) © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e674 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Qiqi He More articles by this author Junsheng Bao More articles by this author Panfeng Shang More articles by this author Li Yang More articles by this author Zhiping Wang More articles by this author Sanjay Gupta More articles by this author Expand All Advertisement PDF downloadLoading ...

Sensitive magnetic particle imaging of haemoglobin degradation for the detection and monitoring of intraplaque haemorrhage in atherosclerosis.

Intraplaque haemorrhage (IPH) drives atherosclerosis progression and is a key imaging biomarker of unstable plaques. Non-invasive and sensitive monitoring of IPH is challenging due to the compositional complexity and dynamic nature of atherosclerotic plaques. Magnetic particle imaging (MPI) is a highly sensitive, radiation-free, and no-tissue-background tomographic technique that detects superparamagnetic nanoparticles. Thus, we aimed to investigate whether MPI can invivo detect and monitor IPH. Thirty human carotid endarterectomy samples were collected and scanned with MPI. The tandem stenosis (TS) model was employed to establish unstable plaques with IPH in ApoE-/- mice. MPI and 7TT1-weighted magnetic resonance imaging (MRI) were performed on TS ApoE-/- mice. Plaque specimens were analyzed histologically. Human carotid endarterectomy samples exhibited endogenous MPI signals, which histologically colocalized with IPH. Invitro experiments identified haemosiderin, a haemoglobin degradation product, as a potential source of MPI signals. Longitudinal MPI of TS ApoE-/- mice detected IPH at unstable plaques, of which MPI signal-to-noise ratio values increased from 6.43±1.74 (four weeks) to 10.55±2.30 (seven weeks) and reduced to 7.23±1.44 (eleven weeks). In contrast, 7TT1-weighted MRI did not detect the small-size IPH (329.91±226.82μm2) at four weeks post-TS. The time-course changes in IPH were shown to correlate with neovessel permeability providing a possible mechanism for signal changes over time. MPI is a highly sensitive imaging technology that allows the identification of atherosclerotic plaques with IPH and may help detect and monitor unstable plaques in patients. This work was supported in part by the Beijing Natural Science Foundation under Grant JQ22023; the National Key Research and Development Program of China under Grant 2017YFA0700401; the National Natural Science Foundation of China under Grant 62027901, 81827808, 81730050, 81870178, 81800221, 81527805, and 81671851; the CAS Youth Innovation Promotion Association under Grant Y2022055 and CAS Key Technology Talent Program; and the Project of High-Level Talents Team Introduction in Zhuhai City (Zhuhai HLHPTP201703).

Locational preferences of high‐level overseas talent returning to China: Evidence from microdata analysis

AbstractWhile Chinese national and local governments have made every effort to attract high‐level overseas talent, limited scholarly attention has been paid to their decision of where to stay in China. Using resume data of 3372 individuals involved in the “Thousand Talent Program”, this study makes the first attempt to identify both regional and personal factors that affect locational choices of overseas talent in China. Descriptive results show that returned talent are unevenly distributed and are mostly concentrated in a few coastal provinces. Results from conditional logit models show that both academic career prospects and (natural and man‐made) amenities play an important role in shaping overseas talent's choices of where to work, but regional prosperity exerts no effect. Alumni social networks, scientific collaboration networks, and educational trajectories are found to greatly influence their locational choices. Results from mixed models suggest that the effect of these provincial factors may vary by age, time spent abroad, the type of talent, the location of undergraduate study, and the country of stay before return. This study enhances our knowledge of the international return migration of the highly skilled by focusing on state‐led academic migration and by challenging the conventional wisdom that high‐level global talent are rootless and cosmopolitan elites with similar locational preferences.

Assessment of the Taekwondo Training Program through Talent Identification: Basis for Enhanced Training Program

The success of a training program is based on the performance of the athletes. Trainers and coaches should seek the talents of their players to develop a productive training program. When identifying an athlete’s potential, Talent Identification Program in Sports is used. This program is used by many countries around the world in their preparation for big sporting events like the Olympics. An effective training program is key to winning, for its goal is to improve the skills or talents of the athletes. One of the sports applying to the said programs is Taekwondo. Based on Sports Industry Research Centre (2003), The International Olympic Committee medal table is largely regarded by the government, the media, and the general public as a measure of a country’s sporting achievement. This study focused on identifying the level of performance of Taekwondo athletes through a standardized physical fitness test. The researcher used Pearson r to correlate the relationship between the BMI and the performance of the student-athletes. Results revealed that athletes with underweight BMI scored advanced and skilled in all fitness tests, while athletes with normal BMI scored also advanced and skilled in physical fitness tests and the athletes with overweight BMI scored skilled and average in the fitness tests conducted. The results of the data analysis showed that there is no significant correlation between the athletes’ skill-related fitness and their BMI. To improve athletes’ abilities regardless of their BMI status, more research is required. Keywords: body mass index (BMI), physical fitness test, reaction time, flexibility, leg power, agility, speed, taekwondo, training program

Quick Understanding Policy Implementation of Merit System in Human Resource Apparatus Management in DKI Jakarta Province

The development of human resources is one of the priority programs of the Government of Indonesia (GOI), including for Aparatur Sipil Negara (ASN) or Indonesian civil services. One way that can be done to improve the quality of ASN is by the implementation of merit-based ASN management in all Indonesian Government Agencies. There are still very few studies that discuss in depth how the policy and implementation of the ASN management merit system, especially in local governments. Moreover, this study uses a case study in DKI Jakarta Province as a local government which is also the capital of the Republic of Indonesia. This study found that the policy implementation of the merit system in the DKI Jakarta Provincial Government is still not fully implemented. Some aspects have gaps, namely career development, promotion, and rotation. Therefore, the purpose of this study is to review the policy implementation of the merit system in the DKI Jakarta Provincial Government. The research method employed in this study is the qualitative approach through interviews, Focus Group Discussions (FGD), observations, and document reviews. The results showed that there was a significant increase in the implementation of merit-based ASN management in the DKI Jakarta Provincial Government. Is can be seen from the increase in the value merit system owned by the DKI Jakarta Provincial Government. The increase is since currently, the DKI Jakarta Provincial Government has built its talent management program.&#x0D; Keywords: Merit system, Human resource apparatus management, Local government, DKI Jakarta Province, Indonesia

Hyperfractionation compared with standard fractionation in intensity-modulated radiotherapy for patients with locally advanced recurrent nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial

Reirradiation in standard fractionation for locally advanced recurrent nasopharyngeal carcinoma after a previous course of high-dose radiotherapy is often associated with substantial late toxicity, negating its overall benefit. We therefore aimed to investigate the efficacy and safety of hyperfractionation compared with standard fractionation in intensity-modulated radiotherapy. This multicentre, randomised, open-label, phase 3 trial was done in three centres in Guangzhou, China. Eligible patients were aged 18-65 years with histopathologically confirmed undifferentiated or differentiated, non-keratinising, advanced locally recurrent nasopharyngeal carcinoma. Participants were randomly assigned (1:1) to either receive hyperfractionation (65 Gy in 54 fractions, given twice daily with an interfractional time interval of at least 6 h) or standard fractionation (60 Gy in 27 fractions, given once a day). Intensity-modulated radiotherapy was used in both groups. A computer program generated the assignment sequence and randomisation was stratified by treatment centre, recurrent tumour stage (T2-T3 vs T4), and recurrent nodal stage (N0 vs N1-N2), determined at the time of randomisation. The two primary endpoints were the incidence of severe late complications defined as the incidence of grade 3 or worse late radiation-induced complications occurring 3 months after the completion of radiotherapy until the latest follow-up in the safety population, and overall survival defined as the time interval from randomisation to death due to any cause in the intention-to-treat population. This trial is registered with ClinicalTrials.gov, NCT02456506. Between July 10, 2015, and Dec 23, 2019, 178 patients were screened for eligibility, 144 of whom were enrolled and randomly assigned to hyperfractionation or standard fractionation (n=72 in each group). 35 (24%) participants were women and 109 (76%) were men. After a median follow-up of 45·0 months (IQR 37·3-53·3), there was a significantly lower incidence of grade 3 or worse late radiation-induced toxicity in the hyperfractionation group (23 [34%] of 68 patients) versus the standard fractionation group (39 [57%] of 68 patients; between-group difference -23% [95% CI -39 to -7]; p=0·023). Patients in the hyperfractionation group had better 3-year overall survival than those in the standard fractionation group (74·6% [95% CI 64·4 to 84·8] vs 55·0% [43·4 to 66·6]; hazard ratio for death 0·54 [95% CI 0·33 to 0·88]; p=0·014). There were fewer grade 5 late complications in the hyperfractionation group (five [7%] nasal haemorrhage) than in the standard fractionation group (16 [24%], including two [3%] nasopharyngeal necrosis, 11 [16%] nasal haemorrhage, and three [4%] temporal lobe necrosis). Hyperfractionated intensity-modulated radiotherapy could significantly decrease the rate of severe late complications and improve overall survival among patients with locally advanced recurrent nasopharyngeal carcinoma. Our findings suggest that hyperfractionated intensity-modulated radiotherapy could be used as the standard of care for these patients. Key-Area Research and Development of Guangdong Province, the National Natural Science Foundation of China, the Special Support Program for High-level Talents in Sun Yat-sen University Cancer Center, the Guangzhou Science and Technology Plan Project, and the National Ten Thousand Talents Program Science and Technology Innovation Leading Talents, Sun Yat-Sen University Clinical Research 5010 Program.

Impact of Acquisition of Digital Skills on Perceived Employability of Youth: Mediating Role of Course Quality

Penang Youth Development Corporation took the “Penang Young Digital Talent Program” initiative to bridge the gap between Malaysian youth’s current digital skills and emerging technologies market demands. The program comprises different online courses such as web design, digital marketing, etc. The objective of this study is to understand the level of participants’ digital competency and, secondly, investigate the impact of participants’ digital competency on their perceived employability and examine the mediating role of course quality. This study employed a cross-section design method, and data were collected using purposive sampling. The participants (Nn= 385) of this program range from 18 to 22 years old, either born in Penang or have resided in Penang for a minimum of 3 years. The data were analyzed using Smart PLS 3.0. Post-online course findings show that digital content creation, information and data literacy, and problem-solving have a significant and positive relationship with perceived employability. Moreover, course quality significantly mediates the impact of communication and collaboration, digital safety and information and data literacy on the perceived employability of Malaysian youth. The findings of this research have implications for policymakers responsible for education, emphasizing youth’s acquisition of digital skills to help them succeed in the current workplace.

The relative age effect in under-17, under-20, and adult elite female soccer players

ABSTRACT To investigate the RAE in elite female soccer players, the absolute and relative birthdate distributions of players who disputed the Women’s World Cup were assessed. Differences between observed and expected distributions were analyzed using chi-square and effect sizes. The birthdates of 1224 female soccer players were assessed in Under-17 (N = 336), Under-20 (N = 336) and adult (N = 552) categories. There was no significant RAE in adult category for different playing positions and players in general (including all playing positions per age category). There was significant RAE for midfielders and players in general with mainly small effect sizes for the U-17 and U-20. In both age categories, players born in Q1 were over-represented with the highest quartile ratio for midfielders. In regard of RAE and success defined by final ranking at the World Cup, we found no significant differences between the birthdate distributions of players who participated in either the group stages or finally the knockout phases. Coaches should consider this information to avoid bias in talent programs designed to promote and select female soccer players independently of their birthdates. Young female players should be encouraged to learn to play in different field positions before to reach high-level performance.

Has China’s Young Thousand Talents program been successful in recruiting and nurturing top-caliber scientists?

In this study, we examined China's Young Thousand Talents (YTT) program and evaluated its effectiveness in recruiting elite expatriate scientists and in nurturing the returnee scientists' productivity. We find that YTT scientists are generally of high caliber in research but, as a group, fall below the top category in pre-return productivity. We further find that YTT scientists are associated with a post-return publication gain across journal-quality tiers. However, this gain mainly takes place in last-authored publications and for high-caliber (albeit not top-caliber) recruits and can be explained by YTT scientists' access to greater funding and larger research teams. This paper has policy implications for the mobility of scientific talent, especially as early-career scientists face growing challenges in accessing research funding in the United States and European Union.

Talent management in Polish companies in the light of empirical studies

Purpose: The aim of the paper is the introduction of talent management practices that are applied in Polish companies in the context of effectively identifying, developing and retaining talent within the company. Design/methodology/approach: The approach applied in the paper is of descriptive-empirical nature. The research methods involved in this paper are: induction, deduction, literature studies, as well survey and data analysis. Findings: On the basis of the analysis of the research material - in the conclusion - recommendations are presented for Polish companies to implement the practices of talent management programs talents. Research implications: Future research directions should focus on further extended research exploration in this area, taking into account various companies, both small, medium and large. Practical implications: The presented research results (from 2006 to 2018) make an important contribution to the existing knowledge on building and implementing talent management programs in a company and have a number of practical implications mainly for HR professionals. Social implications: Building awareness of talent management issues in the company. Originality/value: The research findings and opinions have both theoretical and practical implications, which can be used to shape and optimize management practices with regard to talent employees. The work has cognitive value for managers, HR departments, people managing human resources, as well as for people interested in the topic of talent management and employee development. It may also be of interest to academics, providing them with a source of inspiration for research work. Keywords: talent, talent management, human capital, Polish companies. Category of the paper: research paper.

ВЛИЯНИЕ ЛИЧНОСТНЫХ ХАРАКТЕРИСТИК ТАЛАНТЛИВЫХ СОТРУДНИКОВ НА ИХ ДОБРОВОЛЬНОЕ УВОЛЬНЕНИЕ

Despite the growing interest in talent management issues, there is still no consensus in theliterature regarding the characteristics and features of talented employees work behavior. One of the approaches stands out as an objective view postulating that there are a set of personal characteristics, which determine an employee as a talented one and influence their labor behavior. This research attempts to identify a list of these personal characteristics and assess their impact on work behavior. The list of characteristics incorporates personalitydimensions contained in the Big Five model. As a form of labor behavior is voluntary resignation. The research empirical base is the data on the talent management program at Sheremetyevo International Airport. We constructed econometric probit model, where the fact that a talented employee voluntarily quit during the first year of employment was used as an explanatory variable. The focus on resignations in the first year is related to an attempt to reduce the influence of factors that form sustainable attitudes towards job characteristics - satisfaction and loyalty to the organization. The set of independent variables is represented by organizational and socio-demographic characteristics in addition to personal characteristics.The results confirmed the hypotheses on the influence of higher values of openness to experience, conscientiousness, neuroticism, and extraversion, regardless of the organizational context, on the probability of voluntary turnover. The findings provide an empirical assessment of theobjective approach to talent in the Russian labor market and can be used for verificationin other corporate contexts or while trying to assess their sustainability with a longer work experience. In practical terms, the findings can be used to develop personalized talent management practices in Russian companies

A New Approach to Talent Development at PT Transportasi Angkutan Darat: an in-depth Exploration of Experiential Learning, Coaching, and in-class Training Integration

The 70:20:10 framework stands as a widely acknowledged and effective approach to learning, underscoring the importance of experiential learning and coaching within talent development programs. Recognizing this, PT Transportasi Angkutan Darat (TAD), a railway-based transportation company in Indonesia with operational areas covering the islands of Java and Sumatra, has embraced it as a cornerstone of their talent development initiative. Within this context, a specifically chosen group of TAD employees, identified as high-potential individuals or "Talents," underwent a comprehensive development program structured around the 70:20:10 framework. This encompassed experiential learning, coaching, and training programs. While internal evaluations demonstrated the method's capacity to enhance the performance of these Talents, there remained a need for optimization in developing competencies, especially for those occupying senior management positions. To delve deeper into the program's implementation, semi-structured interviews will be conducted with participants from the talent development program. Specifically, interviews will involve four individuals in senior and middle management positions, along with one person from the program management team serving as the organizer of the talent development program. The study revealed a lack of standardization, particularly in experiential learning and coaching for Talents in senior management roles, resulting in suboptimal outcomes. This identified lack of standardization in the implementation of the Talent Management Program at TAD, particularly in the realms of experiential learning and coaching for senior management Talents, underscores the imperative for targeted enhancements. Addressing these areas of improvement is crucial for achieving the desired and optimal outcomes of the talent development initiative.

УПРАВЛІННЯ МАРКЕТИНГОМ ПЕРСОНАЛУ ПІДПРИЄМСТВ: ВИКЛИКИ ТА ПЕРСПЕКТИВИ

The article examines the problems of managing the marketing of enterprise personnel in the context of modern challenges and threats. The key aspects of enterprise personnel marketing are allocated and a set of measures for their practical implementation is proposed, which will allow an enterprise to strengthen its position in the labor market in terms of attractiveness for potential job seekers, retain its own qualified personnel through training and development opportunities, attract employees with the necessary competencies and skills, and positively affect the overall efficiency of the enterprise and its competitiveness in the future. The main challenges of modern marketing of enterprise personnel are outlined, which are grouped into separate blocks: digitalization and technological development, the increasing importance of the employer's brand, changing the demographic composition of the population, and changing the approach to training and development of personnel. The authors describe modern models of personnel marketing, the practical implementation of which will allow a comprehensive assessment of the company's needs in attracting and retaining employees and developing an effective strategy for building a personnel marketing system. The authors identify promising areas for improving the personnel marketing management system: development of an effective employer branding system; creation and implementation of effective talent attraction programs; implementation of a talent retention system; development of personnel assessment and development tools; support of communication with employees using digital technologies. Also proposed measures for the practical implementation of these perspectives of personnel marketing management, which include the development and implementation of comprehensive strategies for attracting and retaining talent, creation of tools for evaluating the effectiveness of programs for attracting and retaining professionals, the introduction of innovative methods of attracting personnel, development of a system of employee motivation, analysis of the experience and success of competitors in the market for attracting and retaining professionals and implementation of best practices in their own activities, providing support.

集成生态系统服务与生物多样性的系统保护规划

PDF HTML阅读 XML下载 导出引用 引用提醒 集成生态系统服务与生物多样性的系统保护规划 DOI: 10.5846/stxb202112023396 作者: 作者单位: 作者简介: 通讯作者: 中图分类号: 基金项目: 国家自然科学基金项目（32071650，31670539）；云南省中青年学术和技术带头人后备人才项目（202105AC160070）；云南大学研究生科研创新基金项目（2021Y039） Systematic conservation planning by integrating ecosystem services and biodiversity Author: Affiliation: Fund Project: The National Natural Science Foundation of China (grants 32071650, 31670539); Young and Middle-aged Academic and Technical Leaders Reserve Talent Program of Yunnan Province (202105AC160070); Graduate Research innovation project of Yunnan University (2021Y039). 摘要 | 图/表 | 访问统计 | 参考文献 | 相似文献 | 引证文献 | 资源附件 | 文章评论 摘要:生物多样性和生态系统服务的保护与可持续管理是当今世界面临的重大挑战之一，但如何判识与优化集成生态系统服务与生物多样性保护对象的保护优先区网络，相关研究还很有限。针对"三江并流"区，选取珍稀濒危与特有动植物物种和自然植被类型作为生物多样性保护对象，以调节服务（碳存储、固碳和土壤保持）、文化服务（自然游憩）和供给服务（水源供给）为生态系统服务保护对象。应用系统保护规划方法，首先判识出单一生物多样性和生态系统服务保护优先区；然后，分析这些保护优先区间的相关关系，并选择与生物多样性正相关的生态系统服务类型，判识集成生态系统服务与生物多样性的保护优先区；最后，评估了集成生态系统服务与生物多样性保护优先区在六类已建保护地中的保护状况。结果表明：（1）"三江并流"区多情景规划得到的生物多样性与生态系统服务保护优先区之间均呈正相关关系；（2）与分别针对生态系统服务和生物多样性的规划情景相比，集成生态系统服务与生物多样性保护优先区能够同时对两类保护对象提供最高的保护覆盖率；（3）集成生态系统服务和生物多样性保护优先区占研究区总面积的48.9%，其已建保护地覆盖率为32.5%，说明现有保护地体系仍存在保护空缺。 Abstract:Conservation and sustainable management of biodiversity and ecosystem services are one of the major challenges faced by the world today. However, there is still limited research on how to identify and optimize the portfolio of priority conservation areas (PCAs) that integrate ecosystem services and biodiversity as conservation targets. Using the Three Parallel Rivers Region (TPRR) as a case, this study selected representative conservation features for both biodiversity and ecosystem services; biodiversity conservation features included the rare, endangered and endemic plant and animal species and natural vegetation types; ecosystem-service conservation features included regulation services (carbon storage, carbon sequestration and soil retention), cultural services (natural recreation) and supply services (water supply). We firstly identified the individual portfolio of PCAs for biodiversity and each type of ecosystem services by applying a systematic conservation planning approach, respectively. Then, we analyzed the relationship between these different portfolios of PCAs. We identified the PCAs by integrating biodiversity and ecosystem services that had a portfolio of PCAs being positively correlated with biodiversity PCAs. Finally, we assessed the conservation status of the integrated PCAs within six categories of the existing protected areas. The results showed that:(1) there was a positive relationship between different portfolios of the PCAs identified for biodiversity and each type of ecosystem service in TPRR; (2) In comparison with planning scenarios for ecosystem services and biodiversity separately, the PCAs integrating ecosystem services and biodiversity could simultaneously provide the highest coverage for all biodiversity features and ecosystem services; (3) The PCAs integrating ecosystem services and biodiversity covered 48.9% of the study area, and received 32.5% coverage from the protected areas, indicating that conservation gaps still existed in the existing protected-area system. 参考文献 相似文献 引证文献