ObjectiveTo evaluate the effect of more vegetable intake on cardiovascular disease risk factors in hemodialysis (HD) patients.MethodsThis is a cross‐sectional study. All subjects were outpatients from Taipei Medical University Hospital. Fifty‐four HD patients and thirty‐five subjects with eGFR more than 60 ml/min/1.73m2 from department of Family Medicine (control group) were completed this study. The dietary components and nutrients intake was calculated from the average of 3‐day dietary record. Besides, the nutritional markers (dry body weight and serum albumin), inflammatory markers (serum C‐reactive protein), lipid profile (serum total cholesterol, low‐density lipoprotein cholesterol, and triglyceride), serum folate, homocysteine, and potassium, and insulin resistance index were analyzed by Department of Laboratory Medicine of Taipei Medical University Hospital. Both HD patients and control group were dichotomy by median of vegetable intake adjusted by energy, and the cut point in HD patients was 1.05 servings of vegetable/1000 kcal.ResultsComparing with control group, HD patients had significantly higher serum level of C‐reactive protein and homocysteine, and insulin resistance index, but lower serum albumin level. Despite the vegetable intake was not significantly different between HD patients and control group, even after adjusting for energy intake. HD patients with higher vegetable intake had lower serum C‐reactive protein and homocysteine, and insulin resistance index, but did not achieve statistical significance.ConclusionIn HD patients, more vegetable intake may not be associated with improving selected risk factors for cardiovascular disease in this study.