Summary:A number of herbicides and herbicide mixtures which are being used for the post‐emergence control of weeds in maize on the Transvaal Highveld, have been tested for their efficiency in the control of problem weeds. The evaluation was done under standardized conditions. The influence of the herbicides on the plants was evaluated by using the following bioassay methods: percentage mortality and the percentage dry mass difference between the test plants and the control 10 days after treatment.Recommendations are made as to which herbicides could be used most effectively on problem weeds post‐emergence in maize fields. The developmental stage (age) at which each herbicide is most effective, has been determined.