Gender confirming surgery (GCS) is a cornerstone in the treatment of gender dysphoria. Reconstructing genitalia with tactile and erogenous sensitivity is crucial in GCS. To our knowledge, no previous study has compared the sensitivity before and after GCS in transgender women. Our aim was to compare the tactile and vibratory sensitivity before and one month after GCS, on the glans penis and neoclitoris, respectively. Furthermore, the aim was to evaluate if the neoclitoris sensitivity was in line with cis-women and if the patients had achieved orgasm one month after GCS. Eight transgender women were measured regarding sensitivity preoperatively and one month postoperatively on the glans penis and neoclitoris, respectively. Tactile and vibratory sensitivity measurements were performed with Semmes-Weinstein monofilaments and Bio-Thesiometer, respectively. A control group of 10 ciswomen were measured regarding genital sensitivity. The patients received questions concerning orgasm function one month postoperatively. The median tactile and vibratory thresholds for the transgender women’s glans penis were 24.0 g/mm2 and 0.26 μm, respectively. One month postoperatively the median tactile threshold for neoclitoris was 18.1 g/mm2 and the vibratory threshold 0.25 μm. The control group’s median tactile and vibratory thresholds were 1.4 g/mm2 and 0.04 μm, respectively. One of the transgender patients had achieved an orgasm.