The objective of this study was to determine the epidemiological aspects of metaplastic breast cancer, their tumor characteristics and clarify their evolutionary profile. Patients and Methods: This was a retrospective study of 23 cases of breast cancer followed the Joliot-Curie Institute in Dakar during the period 1 January 2007 to 31 December 2011. Results: metaplastic breast cancers were 1.83% of breast cancers observed in the Joliot Curie Institute in Dakar, with a mean age at diagnosis of 42.30 years. The notion of family history of breast cancer was found in 06 patients (26.08%). The mean clinical tumor size was 9.52 cm with a large majority of T3-T4 tumors (69.56%). Staging found 3 patients in stages I and II (13.3%), 9 patients with stage III (39,13%) and 10 patients with stage IV (43.47%). Neoadjuvant chemotherapy was performed in 12 patients or 52.17%. Seventeen patients had received surgery; it was radical surgery in 73.91% of cases. Seven of the operated patients had received adjuvant chemotherapy. Six operated patients (26.08%) received adjuvant radiotherapy. The local recurrence rate in our study was 4.34% with an average of 8.75 months. Three patients had presented metachronous metastases (25%) of the study population. Five patients (21.73%) were alive, 16 patients (69.56%) had died and 2 patients (8.69%) were lost to follow up. Conclusion: A new molecular approach would better codify traditional systemic therapies. Keywords: metaplastic carcinoma - breast - epidemiology - treatment.