Trends In Systolic Blood Pressure Research Articles

Maximal oxygen uptake, muscle strength and walking speed in 85-year-old women: effects of increased physical activity.

This study explores the effect of regular training on blood pressure, maximal oxygen uptake, maximal isometric muscle strength, and walking speed in the very old. A total of 55 community-dwelling women, 85-year-old, were enrolled in a training group (N = 22) or a control group (N = 33). These groups were reduced to 19 and 26 subjects, respectively, after the training period. Training was performed once a week over eight months, and consisted of various exercises with particular attention to movements important for everyday activities. Training reduced diastolic blood pressure (p < 0.05), and showed a similar trend for systolic blood pressure. Measurements of maximal oxygen uptake before the start of the training (15 mL min-1 kg-1) revealed a level close to the presumed limit for independent living (13 mL min-1 kg-1). Training improved VO2 max by 18% (p < 0.05), whereas the control group experienced a trend towards a reduction. Maximal isometric muscle strength of both the right and left leg showed a tendency to increase with training, but no significant changes were evident in the trunk flexor and extensor muscles. The training group showed a significant increase of 17% in maximal walking speed after the training period. However, one year later, without training, this improvement was reduced to 8% (p < 0.05). No major changes were observed in the control group for any of these parameters. This study demonstrates a maximal oxygen capacity in very old community-dwelling women close to a threshold level indicating dependency. Furthermore, 8 months of regular training appears to lower blood pressure, and to increase maximal oxygen uptake and maximal walking speed. This suggests that physical reactivation of the very old may reduce the risk for acquiring age-related diseases associated with an elevated blood pressure, and may improve parameters crucial for independence.

The effects of repeated occlusion measurement on blood pressure and pulse rate

We examined the effects of repeated occlusion measurement on blood pressure and pulse rate during rest and during mental arithmetic stress. Participants performed two rest-and-task sequences. We took automated blood pressure readings during each minute of one rest-and-task sequence (i.e. all-minutes measurement strategy), and during every other minute for the other sequence (i.e. odd-minutes measurement strategy). Each rest-and-task period was 5 min long and we counterbalanced the two rest-and-task sequences for order. Overall, baselines, task levels and reactivity scores were highly similar across the two measurement strategies. We did, however, find small but reliable measurement strategy effects that interacted with task novelty, particularly for DBP. Specifically, DBP levels and reactivity were lower during the all-minutes measurement strategy compared to the odd-minutes strategy, particularly during the second of two repeated tasks. We observed a similar trend for systolic blood pressure, but did not for mean arterial pressure or pulse rate. Our significant effects were small, however, and they should not overshadow the high degree of similarity of results produced by the two measurement strategies.

Systolic blood pressure trends in US adults between 1960 and 1980: influence of antihypertensive drug therapy.

Recent blood pressure trends reflect progress in hypertension control, but prevalent drug therapy precludes direct estimation of the component due to primary prevention. In data gathered on persons aged 35-74 years in three successive US health examination surveys (1960-1980), systolic blood pressure levels assuming no drug therapy were imputed by reassigning blood pressure to the upper end of the distribution for respondents reporting use of antihypertensive medication. Blood pressure was partitioned into four ordinal categories based on weighted percentiles of the 1960-1962 distributions for 35- to 44-year-old males and females who reported no use of antihypertensive medication. Cumulative logit models (alpha = 0.01) were used to estimate age- and sex-specific trends for blacks and whites within two strata (<25 or > or =25) of body mass index (BMI) (weight (kg)/height (m)2). Before imputation, systolic blood pressure decreased between 1960 and 1980; after imputation, significant decreases remained only in 35- to 44-year-olds. Strong associations of black race and BMI > or =25 with higher blood pressures were present in models with and without drug therapy. Thus, according to the models, there has been little progress in decreasing racial or BMI-related blood pressure differentials. Above the age of 44 years, blood pressure trends were largely attributable to medication use. In contrast, data for 35- to 44-year-olds suggest progress in primary prevention.

Serial changes in blood pressure from childhood into young adulthood for females in relation to body mass index and maturational age.

This study determines: (1) patterns of change from childhood to young adulthood in body mass index (BMI), systolic blood pressure (SBP), and diastolic blood pressure (DBP), (2) effects of elevated BMI values on changes in blood pressures (BP), (3) extent of tracking for SBP, DBP, and BMI, and (4) prediction of future risk for elevated BP from earlier values. Annual serial BP and BMI data were available for 198 white females, ages 8-22 years, enrolled in the Fels Longitudinal Study. Patterns of change in BMI were described by a random effects model with a time series model for the correlated residuals. Serial BMI measures were differentiated from age-specific means to measure relative individual BMI levels. Serial BP were analyzed using a similar model to the BMI where relative individual BMI levels were included as an explanatory variable. There was a general increasing trend for SBP, DBP, and BMI from 8-22 years, but the rates of increase declined with age. At the same chronological age, early menarche females had a significantly greater BMI mean value than late menarche females. An average increase of 1 kg/m2 in deviation from BMI population means resulted in an average increase of 1.2 mmHg in SBP and 0.6 mmHg in DBP. Having SBP and DBP levels 1 standard deviation above mean levels, relative to females at mean levels, as early as age 9 represents an odds ratio of 2 for exceeding national 75th percentile levels of SBP and DBP at age 21. Am. J. Hum. Biol. 10: 589-598, 1998. © 1998 Wiley-Liss, Inc.

Blood pressure, self-reported symptoms and job-related problems in schoolteachers

The relationship between blood pressure and self-reports of physical symptoms and job-related problems was investigated in a sample of 262 male and female teachers. The subjects were divided into three groups: treated hypertensives (THT, N = 23); untreated hypertensives (UHT, N = 101); and normotensives (NT, N = 123). After controlling for eight potentially confounding variables, the groups differed significantly with respect to reported physical symptoms, with THT reporting the most and UHT the fewest symptoms. Moreover, after controlling for potential confounders, a multiple regression analysis revealed an inverse association between diastolic blood pressure and the number of reported physical symptoms in untreated subjects. A similar trend for systolic blood pressure did not reach significance. In addition, no significant results with respect to work-related problems were obtained, except for a group × gender interaction on job-related irritation: male THT showed lowest and female THT highest irritation scores. The potential role of altered appraisal, diagnosis, and gender are discussed.

Correlation Between Systolic Blood Pressure and Physical Development in Adolescene

Although the close relation between blood pressure and physical development in adolescence has been established in cross-sectional and comparative cross-sectional studies, the entire trend of systolic blood pressure (SBP) during adolescence has not been elucidated in conjunction with physical development in a longitudinal study. Blood pressure (mmHg), body weight (kg), and body height (m) were measured annually for 418 subjects in Hiroshima and Nagasaki, Japan, from age 10 (1955 or 1956) through 18 years (1963 or 1964). The Gompertz growth model was used to determine the velocity of weight increase (VEL) during that age period. The relations between SBP from age 10 to 18 and VEL, weight, height, body mass index (BMI; weight/height2, kg/m2), and the age at which the measurements were made were investigated individually using random-coefficient growth-curve analysis. The SBP trend for the 10- to 18-year age period could be shown by the following prediction equations: for the 163 Hiroshima males, SBP = 82.38 + 0.89 VEL at age 1.15 years prior to the current examination (VEL (age - 1.15)) + 1.40 BMI; for the 57 Nagasaki males, SBP = 92.70 + 1.07 VEL (age - 1.15) + 0.79 BMI; for the 148 Hiroshima females, SBP = 104.88 + 1.63 VEL (age - 1.15) + 0.05 BMI; for the 50 Nagasaki females, SBP = 113.62 + 1.67 VEL (age - 1.15) - 0.59 BMI. VEL 1.15 years prior to the current examination was significantly and positively related to SBP in each city by sex group (p < 0.01), and current BMI was significantly related to SBP for males in Hiroshima (p < 0.01) and nearly so in Nagasaki (p = 0.06), but not for females in either city (p = 0.84 and 0.13, respectively). Because the plot of VEL was a convex curve, SBP peaked approximately 1-2 years after the peak in VEL and then decreased in both sexes. The entire SBP trend during adolescence can be expressed as an equation of VEL and BMI in males and of VEL in females. SBP does not increase linearly with age.

Genetic and environmental influences on blood pressure in elderly twins.

We used 289 pairs of Swedish twins reared apart or together to evaluate the importance of genetic and environmental influences on blood pressure. Unlike other twin and family studies, the adoption/twin design allows a distinction between estimates of the importance of shared rearing environments and genetic effects. Genetic factors were observed to play an important role for individual differences in blood pressure. Model-fitting analyses suggested upper limits of heritability for systolic and diastolic blood pressures in the entire sample of 0.44 and 0.34, respectively. More interestingly, substantial influences of shared family effects accounting for up to 27% of the variation were also revealed. Effects of correlated environment, which might reflect, for example, the intrauterine environment, existed to some extent later in life. The influence of genetic factors tended to decrease across age groups for systolic blood pressure (0.62 in individuals less than 65 years old; 0.12 in those 65 years and older) but not for diastolic blood pressure (0.22 for the middle-aged group; 0.26 for the older group). However, this declining trend for systolic blood pressure did not reach significance (chi 2 = 8.07, df = 4, P = .09).

Trends in systolic blood pressure, 24-hour sodium excretion, and stroke mortality in the elderly in Belgium

Data from six surveys of systolic blood pressure conducted in Belgium between 1967 and 1986 were analyzed. The mean ages of the six groups of 3,328 subjects ranged from 70 to 81 years. The prevalence of systolic blood pressure levels above 159 mm Hg decreased between 1967 and 1986 from 51% to 21% in men and 66% to 22% in women; severe hypertensive (systolic blood pressure >220 mm Hg) nearly disappeared. During the same period, body mass index increased 1.1 kg/m 2 in men and was unchanged in women; mean systolic blood pressure decreased from 159 to 142 mm Hg in men and from 171 to 147 mm Hg in women; the proportion of subjects receiving treatment for hypertension increased from 10% to 36% in men and from 18% to 41% in women; and the mean standardized 24-hour sodium excretion decreased from 265 to 188 mmol in men and from 208 to 160 mmol in women. Systolic blood pressure levels were significantly and independently related to sodium excretion in the 1967 and 1972 studies. The decrease in systolic blood pressure in Belgium was influenced by the combined effects of more and better treatment for hypertension and a decrease in sodium intake.

Trends in systolic blood pressure in the thousand aviator cohort over a twenty-four-year period.

A cohort of 1,056 normotensive, healthy, young men initially examined in 1940 at the mean age of 24 years was followed at three periodic intervals through 1964. The cohort demonstrated little rise in mean systolic blood pressure beyond age 35; a portion of this cohort showed no change of systolic blood pressure with age. If the men are classified by quintile according to systolic blood pressure in 1940, those men in the upper quintile tend to remain high; when classified by quintile in 1951, those men at the extremes maintained their relative position through 1964. Predictive utility of a systolic blood pressure may be a function of its actual level as well as the age of the individual. Two factors further influenced the systolic blood pressure of this cohort, namely, parental longevity and gain in weight. The significant effect of parental longevity became less important relative to gain in weight as time progressed and after 1940 affected primarily those men who had gained weight.