Fluid management in burn patients undergoing general surgery poses unique challenges due to the complex pathophysiological changes associated with burn injuries. Effective resuscitation and perioperative fluid therapy are critical in optimizing outcomes and minimizing complications in this vulnerable patient population. This review explores the latest evidence-based approaches to fluid management in burn patients, emphasizing the importance of individualized strategies that consider burn size, depth, patient age, comorbidities, and surgical factors. We examine the role of advanced hemodynamic monitoring, crystalloid versus colloid solutions, and the integration of goal-directed therapy protocols. Additionally, we discuss the implications of burn-related complications such as systemic inflammatory response syndrome (SIRS), sepsis, and multi-organ dysfunction on fluid management strategies. By synthesizing current research and clinical guidelines, this review aims to provide a comprehensive framework for clinicians to enhance perioperative care in burn patients undergoing general surgery.