Case Reports1 March 1943LARYNGEAL AND SYSTEMIC HISTOPLASMOSIS (DARLING)PAUL A. VAN PERNIS, M.D., MIRIAM E. BENSON, S.B., PAUL H. HOLINGER, M.D.PAUL A. VAN PERNIS, M.D.Search for more papers by this author, MIRIAM E. BENSON, S.B.Search for more papers by this author, PAUL H. HOLINGER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-18-3-384 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMedical interest in histoplasmosis (Darling) has been aroused recently by the increased number of reports published. These accounts indicate that this endemic disease has become more prevalent or that it has existed unrecognized. The difficulties encountered in clinical diagnosis of the disease are due apparently to the variety of symptoms presented by these patients. The specific organism has been isolated by cultures in only a few patients during life or from tissues post mortem. There is no information concerning the morbidity of the disease because all patients known to have had the infection have died. Little is known about the...Bibliography1. HUMPHREY AA: Reticuloendothelial cytomycosis (Histoplasmosis of Darling), Arch. Int. Med., 1940, lxv, 902-918. CrossrefGoogle Scholar2. DEMONBREUN WA: The dog as a natural host for Histoplasma capsulatum , Am. Jr. Trop. Med., 1939, xix, 565-587. CrossrefGoogle Scholar3. WATSON CJ: The pathology of histoplasmosis (Darling) with special reference to the origin of the phagocytic cells, Folia haematol., 1928, xxxvii, 70-93. Google Scholar4. DARLING ST: Histoplasmosis: A fatal infectious disease resembling Kala-Azar found among the natives of tropical America, Arch. Int. Med., 1908, ii, 107. CrossrefGoogle Scholar5. MELENEY HE: Histoplasmosis (reticuloendothelial cytomycosis); A review with mention of 13 unpublished cases, Am. Jr. Trop. Med., 1940, xx, 603-616. CrossrefGoogle Scholar6. MOORE M: Posadasia pyriformis and Posadasia capsulata, two causative organisms of Darling's histoplasmosis in the United States, Ann. Mo. Bot. Gardens, 1934, xxi, 347. CrossrefGoogle Scholar7. BROWNHAVENSMAGATH AEFZTB: Histoplasmosis: Report of a case, Proc. Staff Meet. Mayo Clin., 1940, xv, 812-816. Google Scholar8. VAN PERNISBENSONHOLINGER PAMEPH: Specific cutaneous reactions with histoplasmosis, Jr. Am. Med. Assoc., 1941, cxvii, 436-437. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication August 25, 1941.From the Henry Baird Favill Laboratory and the Department of Peroral Endoscopy of St. Luke's Hospital, Chicago, Illinois.†The John Jay Borland Fellow in Clinical Research. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPrimary Adrenal Insufficiency Caused by Disseminated Histoplasmosis: Report of Two CasesHistoplasmosis of the larynxHistoplasmosisHistoplasmosisAddison's disease associated with histoplasmosisHistoplasmosisDie Krankheiten der Leber und der GallenwegeXLIV Benign Tumors of the LarynxXXII Histoplasmosis of the LarynxHistoplasmosis 1 March 1943Volume 18, Issue 3Page: 384-393KeywordsEndoscopyHistoplasmosisInfectious diseasesMorbidityResearch laboratories ePublished: 1 December 2008 Issue Published: 1 March 1943 PDF downloadLoading ...