Understanding Of Systems Research Articles

Regulate against the machine: how the EU mitigates AI harm to democracy

ABSTRACT Democracies are under attack from various sides. In recent years AI-powered techniques such as profiling, targeting, election manipulation, and massive disinformation campaigns via social bots and troll farms challenge the very foundations of democratic systems. Against this background, demands for regulating AI have gotten louder. In this paper, we focus on the European Union (EU) as the actor that has gone the furthest in terms of regulating AI. We therefore ask: What kind of instruments does the EU envision in their binding and non-binding documents to prevent AI harm to democracy? And what critique can be formulated regarding these instruments? To address these questions, the article makes two contributions. First, by building on a systematic understanding of deliberative democracy, we introduce the distinction between two types of harm that can arise from the widespread use of AI: rights-based harm and systemic harm. Second, by analysing a number of EU documents, including the GDPR, the AI Act, the TTAP, and the DSA, we argue that the EU envisions four primary instruments for safeguarding democracy from the harmful use of AI: prohibition, transparency, risk management, and digital education. While these instruments provide a relatively high level of protection for rights-based AI harm, there is still ample space for these technologies to produce systemic harm to democracy.

Research Trends in Family-Centered Care for Children With Chronic Disease: Keyword Network Analysis.

Family-centered care is an approach to promote the health and well-being of children with chronic diseases and their families. This study aims to explore the knowledge components, structures, and research trends related to family-centered care for children with chronic conditions. We conducted the keyword network analysis in three stages using the keywords provided by the authors of each study: (1) search and screening of relevant studies, (2) keyword extraction and refinement, and (3) data analysis and visualization. The core keywords were child, adolescence, parent, and disabled. Four cohesive subgroups were identified through degree centrality. Research trends in the three phases of a recent decade have been changed. With the systematic understanding of the context of the knowledge structure, the future research and effective strategy establishment are suggested based on family-centered care for children with chronic disease.

Estimates of the Isotope Effect for Nitrate Assimilation in the Indian Sector of the Southern Ocean

AbstractThe Southern Ocean is a high‐nutrient, low‐chlorophyll (HNLC) region characterized by incomplete nitrate (NO3−) consumption by phytoplankton in surface waters. During this incomplete consumption, phytoplankton preferentially assimilate the 14N‐ versus the 15N‐bearing form of NO3−, quantified as the NO3− assimilation isotope effect (15ε). Previous summertime estimates of the 15ε from HNLC regions range from 4 to 11‰. While culture work has shown that the 15ε varies among phytoplankton species, as well as with light and iron stress, we lack a systematic understanding of how and why the 15ε varies in the field. Here we estimate the 15ε from water‐column profile and surface‐water samples collected in the Indian sector of the Southern Ocean—the first leg of the Antarctic Circumnavigation Expedition (December 2016–January 2017) and the Crossroads transect (April 2016). Consistent with prior work in the mid‐to‐late summer Southern Ocean, we estimate a higher 15ε (8.9 ± 0.6‰) for the northern Subantarctic Zone and a lower 15ε (5.4 ± 0.9‰) at and south of the Subantarctic Front. We interpret our data in the context of coincident measurements of phytoplankton community composition and estimates of iron and light stress. Similar to prior work, we find a significant, negative relationship between the 15ε and the average mixed‐layer photosynthetically active radiation flux of 30–100 μmol m−2 s−1, while above 100 μmol m−2 s−1, 15ε increases again. In addition, while we observe no robust relationship of the 15ε to iron availability or phytoplankton community, mixed‐layer nitrification over the Kerguelen Plateau appears to strongly influence its magnitude.

Population Density in Nineteenth-Century American Urbanism

Population density and size are the most commonly used metrics for defining modern cities and urbanism. Yet unlike size, density has been overlooked in systematic analyses of the historical development of the U.S. urban system. Deploying large-scale geocoded census microdata on forty major cities in 1880, this article contributes to a systematic understanding of density in late-nineteenth-century U.S. urbanism. Methodologically, we make the case for a block-level, population-weighted density measure that reflects the experience of density and is transferable to other urban contexts. Thematically, we use this measure to compare density across cities, outlining regionally distinct patterns in density and identifying the built environment as a contributing factor to high- versus low-density urban development, and to explore density within cities across population subgroups, finding that immigrants, racial minorities, and lower class residents experienced higher densities at a time when high density increased exposure to health risks. Additionally, throughout the article we draw out preliminary findings worthy of future research about density conditions for particular cities, places, and demographic subgroups.

Reprint of: Profiling the plight of disconnected youth in America

In a successful transition from youth to adulthood, individuals pass through a sequence of roles involving school, work, and family formation that culminate in their becoming self-sufficient adults. However, some “disconnected” youth spend extended periods of time outside of any role that constitutes an element of the pathway towards adult independence. Assisting these youth requires a systematic understanding of what “disconnection” means, how many disconnected youth there are, who these youth are, and how the scale of the problem has evolved over time. Using the National Longitudinal Surveys of Youth for 1997 and 1979, we address these issues by creating concrete definitions of “disconnection spells” using rich data on youths’ enrollment, work, and personal histories. We estimate a multi-state duration model to account for right censoring and to understand differences across salient sub-groups. Our estimates imply that in the early 2000s, almost 19% and 25% of young men and young women, respectively, experienced a disconnection spell by age 23 using our basic definition. These rates are substantially higher for certain sub-groups defined by race/ethnicity, parental education, and government aid receipt, rising as high as 30+% by age 23. Approximately 60% of youth with a disconnection spell have it last longer than a year, and close to 10% have it last longer than 4 years. However, once reconnected, a majority of youth go at least three years without a re-disconnection spell. Patterns of initial disconnection changed markedly from the 1980s to the 2000s, as young women saw a 12 percentage point decline over time. Moreover, the Black-White gap in disconnection has fallen for women, but increased for men. Our profile of disconnection experiences provides a starting point for government agencies aiming to understand where, how, and with whom to intervene to prevent lengthy disconnection spells.

Understanding tourism in social farming as a form of social innovation

Tourism in social farming contexts has important implications for the inclusive development of rural areas. However, current literature on the topic is still scarce and many organizational aspects of this activity are still unexplored. To provide a systematic understanding of the phenomenon, this study presents a literature review to identify tourism in social farming as a form of social innovation. The results of this research reveal how tourism in social farming responds to specific societal challenges, how it fosters social actors' agency and which kind of relationships it stimulates among them. In the end, a comprehensive framework is proposed. Conclusions will detail the theoretical and practical implications of this study while leaving room for reflection on future research.

Modern concepts of dehumanization of art

The philosophy of art is an important aspect of the study of art and culture, playing a key role in understand-ing the fundamental concepts and ideas behind various art forms. In this article, we examinedthe basic con-cepts of the philosophy of art and their influence on modern culture, as well as exploredthe humanizing sig-nificance of art. The goal of this study is to develop a systematic understanding of the nature of art from a so-cial philosophy perspective, revealing its humanizing role in shaping personality, and analyzing the essential characteristics of “new art”in the context of Ortega y Gasset's teachings. While there are numerous theories of art, it cannot be claimed that its essence, specificity, and social significance are fully comprehended, with debatable issues remaining in its understanding. The complexity and multifaceted nature of art as a phenome-non of human life make it challenging to create a complete and final theory. It is difficult to say that this issue has been sufficiently addressed in our country, as it reflects our society and requires complex philosophical consideration.

Aesthetic Grounds and Practice of Screen Adaptations of Theatrical Productions in the Light of Film and Television Language in the 1970s

The aesthetic grounds and methods of screen adaptation of theatrical performances in the context of film and television art in the USSR in the 1970s are investigated in the article as well as the influence of film and television technologies on the theatrical genre, the peculiarities of the adaptation of stage performances to the cinematographic and television environment. Attention is also paid to the revealing the peculiarities of cinematographic art as a synthetic phenomenon and its interaction with the theatrical tradition. These issues are considered in the context of the cultural and political realities of the USSR of that period, highlighting the relationship between aesthetic searches and ideological attitudes of the era. In general, a deep and systematic understanding of the process of film adaptation of theatrical performances within the framework of Soviet cinema and television art of the 1970s is submitted in the article. Since the films of this period become a time of development of existential problems of human life. The typical life of a Soviet person recedes into the background, instead, the basis of the plot becomes the search for peace of the soul, its urges for freedom, which usually unfolds against the background of something insignificant. Unlike the adaptations of literary works, when ”current ideological content” is imposed on classical original sources, adaptations of the best plays of leading Ukrainian theaters have offered perfect art, introduced a wide audience to the achievements of stage masters. But the screen adaptation of the performance is a fixation of one staging, which, of course, is shown unchanged on movie screens. The play cannot remain as it is conceived from the very beginning, and therefore gradually it has started to transform itself according to the requirements of television. However, such transformations are not always successful either. This is the beginning of the creation of a kind of the average genre between cinema and theater, which wished for better, because the aesthetic content of such a specific genre has remained opened.

An Empirical Analysis of Servant Leadership's Impact on Psychological Wellbeing and Employee Creativity in the Healthcare Sector

The study explores the role and impact of servant leadership (SL) on employee psychological well-being and creativity in the healthcare industry. SL, rooted in traditional values, prioritizes others' needs and promotes moral behavior and ethical viewpoints. The study explores the impact of social learning (SL) on employee creativity and psychological well-being in the healthcare sector, demonstrating its alignment with the profession's commitment to quality patient care. The study postulates and empirically show the favorable relationships between SL and employee creativity and psychological well-being, building on the “Job Demands-Resources (JD-R) theory”. A study was conducted using an online survey to gather data on physicians' perspectives and features in the hospital setting. The survey, conducted in collaboration with healthcare providers, involved 122 physicians aged 18-40+, with 49% female and 51% male. Data was collected using Google Forms, and participants' experiences ranged from 5 to over 20 years. The study used convenience and purposive sampling approaches to increase sample diversity. Despite limitations like self-administrative data and selection bias, the technique provided a systematic understanding of physicians' perspectives and hospital settings. The study reveals a strong positive correlation between employee creativity (EC) and servant leadership (SL), highlighting its role in fostering innovative workplace cultures. It also reveals a strong correlation between SL and psychological well-being, confirming its ability to improve mental health and job happiness in healthcare workers. The study's theoretical implications integrate the JD-R theory and provide insights into contextual elements affecting SL effectiveness. Companies are encouraged to incorporate SL practices into their management strategies to promote creativity and prioritize employee welfare. However, the study's shortcomings, such as its cross-sectional methodology and geographical focus, suggest the need for more research projects. The study concludes that an effective leadership style is servant leadership in the healthcare industry, promoting creative and healthy work cultures.

The supramolecular synthon behavior within cocrystals of pyrazinamide and alkyl dicarboxylic acids: A perspective from terahertz spectroscopy and quantum chemical calculation

Pyrazinamide (PZA) is a widely-used anti-tuberculosis pharmaceutical, but its poor solubility prompts us to optimize pharmaceutical performance. Cocrystallization is a promising technique to improve physiochemical properties of active pharmaceutical ingredient (API) by connecting it with cocrystal former (CCF) via intermolecular interactions. Even though a series of alkyl dicarboxylic acids are employed to form cocrystal structures, systematic understanding on the role of intermolecular interactions is still missing. Therefore, terahertz (THz) spectroscopy and quantum chemical calculation are combined to elucidate the behavior of ubiquitous supramolecular synthons, such as hetero-synthons of acid-pyrazine, acid-amide and homo-synthon of amide-amide, from energy's view. Potential energy is calculated to differentiate the stability within polymorphs of PZA-MA cocrystal and free energy is evaluated to compare the solubility of PZA-CCF cocrystals respectively. With regard to vibrational energy, THz spectral fingerprints are theoretically assigned to specific vibrations and attributed to the flexibility deformation of supramolecular synthons based on oscillation theory, where stretching and twisting modes dominate the collective vibrational behavior. It provides a promising tool to evaluate cocrystal performance from its driving force and insightful guidance to discover new pharmaceutical cocrystals.

Computational and Experimental Characterization of Aligned Collagen across Varied Crosslinking Degrees.

Collagen-based scaffolds have been widely used in tissue engineering. The alignment of collagen fibers and the degree of crosslinking in engineering tissue scaffolds significantly affect cell activity and scaffold stability. Changes in microarchitecture and crosslinking degree also impact the mechanical properties of collagen scaffolds. A clear understanding of the effects of collagen alignment and crosslinking degrees can help properly control these critical parameters for fabricating collagen scaffolds with desired mechanical properties. In this study, combined uniaxial mechanical testing and finite element method (FEM) were used to quantify the effects of fiber alignment and crosslinking degree on the mechanical properties of collagen threads. We have fabricated electrochemically aligned collagen (ELAC) and compared it with randomly distributed collagen at varying crosslinking degrees, which depend on genipin concentrations of 0.1% or 2% for crosslinking durations of 1, 4, and 24 h. Our results indicate that aligned collagen fibers and higher crosslinking degree contribute to a larger Young's modulus. Specifically, aligned fiber structure, compared to random collagen, significantly increases Young's modulus by 112.7% at a 25% crosslinking degree (0.1% (4 h), i.e., 0.1% genipin concentration with a crosslinking duration of 4 h). Moreover, the ELAC Young's modulus increased by 90.3% as the crosslinking degree doubled by changing the genipin concentration from 0.1% to 2% with the same 4 h crosslinking duration. Furthermore, verified computational models can predict mechanical properties based on specific crosslinking degrees and fiber alignments, which facilitate the controlled fabrication of collagen threads. This combined experimental and computational approach provides a systematic understanding of the interplay among fiber alignment, crosslinking parameters, and mechanical performance of collagen scaffolds. This work will enable the precise fabrication of collagen threads for desired tissue engineering performance, potentially advancing tissue engineering applications.

Global research trends on the links between prostate cancer and erectile dysfunction between 2003 and 2023: A bibliometrics and visualized study

BackgroundThe incidence of prostate cancer (PC) has increased in recent years. Erectile dysfunction (ED) after prostate cancer treatment has aroused extensive attention. Bibliometric analysis was designed to investigate a systematic understanding of developments between PC and ED during the past 20 years. MethodsLiteratures on PC and ED were retrieved from the Web of Science Core Collection database (WoSCC). By using the VOS viewer and CiteSpace software to analysis the metrics of bibliometric literature, such as number of articles, journals, countries, institutions, authors, keywords and associated information. The number of publications per year was statistically analysed and plotted thorough Microsoft Office. In addition, Pajek software was used to adjust the visual map. ResultsA total of 2332 screened articles were included in the analysis. The Journal of Sexual Medicine, ranking first among the analysed journals, published 235 articles. The United States and Canada were leaders in PC and ED research. There is a need to strengthen inter-agency cooperation in this area of research on a global scale. Mulhall JP, as the most prolific author in this area of research, published 80 articles. And Rosen RC was the author with the most co-citated (693 co-citated). The main research focus on the prevention, treatment and management of ED after PC treatment in this field through the keyword analysis. ConclusionsResearch on PC and ED is expected to expand further worldwide. We found ED, as new sustainable treatment modalities, scientific postoperative management and psychological interventions for patients, may become the research hotspots and should be closely concerned in this study.

DeTELpy: Python package for high-throughput detection of amino acid substitutions in mass spectrometry datasets.

Errors in the processing of genetic information during protein synthesis can lead to phenotypic mutations, such as amino acid substitutions, e.g. by transcription or translation errors. While genetic mutations can be readily identified using DNA sequencing, and mutations due to transcription errors by RNA sequencing, translation errors can only be identified proteome-wide using mass spectrometry. Here, we provide a Python package implementation of a high-throughput pipeline to detect amino acid substitutions in mass spectrometry datasets. Our tools enable users to process hundreds of mass spectrometry datasets in batch mode to detect amino acid substitutions and calculate codon-specific and site-specific translation error rates. deTELpy will facilitate the systematic understanding of amino acid misincorporation rates (translation error rates), and the inference of error models across organisms and under stress conditions, such as drug treatment or disease conditions. deTELpy is implemented in Python 3 and is freely available with detailed documentation and practical examples at https://git.mpi-cbg.de/tothpetroczylab/detelpy and https://pypi.org/project/deTELpy/ and can be easily installed via pip install deTELpy.

Unraveling the significance of acid sites in determining NH3-SCR mechanisms over WO3 catalyst: A combined experimental and computational study

With regard to the catalysts for NH3 selective catalytic reduction (NH3-SCR), the acid sites distribution can affect the adsorption of reactants and formation of intermediates, thus determining the reaction routines. In this work, a representative acidic component, monoclinic-WO3 (m-WO3), was used to probe the combination strategy of experimental and theoretical research, aiming at systematic understanding on the full-process mechanisms. Macro-scale characterizations, Temperature Programmed Desorption (TPD) and Temperature Programmed Reduction (TPR), are associated with the Density Functional Theory (DFT) calculations, by which W ion (Lewis acid site) is affirmed as the active sites. By comparing the energy barriers of possible pathways with DFT calculations, we identify that NH2NO and NHNOH are responsible active intermediates. Both Langmuir-Hinshelwood (L-H) and Eley-Rideal (E-R) pathways may take place on acid sites and the former on Lewis acid site is optimal, which agrees well the in situ diffuse reflectance infrared Fourier transform spectroscopy (in situ DRIFTS) analysis. This study offers a reasonable prototype for precisely examining the correlation between the catalyst and mechanisms of NH3-SCR catalysts.

System and Policy of Land Administration in Our Country

Through the study of land management in this semester, I have a relatively systematic understanding of China's land management policies, a series of land use systems and some programs implemented by the country for land. China's land area of 9.6 million square meters, is a vast country, so the implementation of some land management rules are extremely necessary. Reasonable control of land is an effective way to prevent land from being destroyed or the utilization rate is very low. Rational use of land resources is the full embodiment of this idea. Next, I will discuss from three aspects to conclude the final paper of the course of land management in this semester.

Study of Electrochromic Properties of PEDOT:PSS for Tunable Filter Optics with Lithium Salt Electrolyte

Nowadays, conductive polymers based on poly(3,4-ethylenedioxythiophene), poly(styrene sulfonic acid), or PEDOT:PSS, have been employed as a flexible and transparent coating in various significant electronic applications. With the demand for electrochromic properties, such as in electronic displays, further research into its electrooptic properties is required, especially the systematic understanding to obtain the optimized switching. Our research investigates the electrooptic properties of the PEDOT:PSS film, particularly the refractive index changing under various applied biases. The electrochromic device is prepared in a simple fashion, and the electroactive layer of PEDOT:PSS thickness is defined via spin-coating between two indium tin oxide (ITO) substrates. To increase the switching properties of PEDOT:PSS, lithium perchlorate (LiClO4) was prepared in acetonitrile, as the electrolyte in varied concentrations of 1.195 M, 1.5 M, and 2.0 M, respectively. A potential voltage of -4.0 V to 0.0 V is utilized to study the device's electrochromic properties with the step 5 mV/s continuously. Finally, the optical properties are characterized using the spectroscopy method based on real-time measurement of the transmission spectrum and transmission matrix calculations. The change in visible light absorption, transmission, and film color is recorded under a switching cycle that shows consistent behavior. This allows the further utilization of such a hybrid structure for possible tunable filter applications. Keywords: Electrochromic, PEDOT:PSS, Optical, Lithium salt, Electrolyte

ESL teachers’ metalanguage as evidence of their metalinguistic knowledge of the English intonation system

The present study investigated six experienced English as a second language (ESL) teachers’ metalinguistic knowledge of the English intonation system through analysis of their metalanguage. Participants’ metalanguage related to intonation was collected while completing three tasks: (1) a semi-structured interview, (2) a simulated teaching demonstration, and (3) a pronunciation needs assessment. Qualitative content analysis revealed information related to their metalinguistic knowledge of the intonation subsystems of parsing, prominence, and pitch contour. Although broad patterns of metalinguistic knowledge across participants were evident, metalanguage variation showed individual differences in conceptualization and descriptiveness of the subsystems, suggesting a lack of a systematic and in-depth understanding of the characteristics and functions of the interrelated subsystems. Findings highlight the need to enhance teachers’ metalinguistic knowledge of the English intonation system, with more emphasis on the interconnectivity of intonational features and contextual meaning-making phenomena of intonation. The study provides implications for second language (L2) teacher educators and education programmes, suggesting that more attention should be given to teachers’ use of metalanguage for explicit pronunciation instruction. In addition, more training opportunities are needed to foster a systematic and in-depth understanding of the intonation system.

Deprotonation of formic, acetic acids and bicarbonate ion in slit silica nanopores at infinite dilution and in the presence of electrolytes

Dielectric effects and the coupled electrostatics between the nanoconfined and the internal/external aqueous media contribute to the observed deviations of chemistry within the nanoconfined environment when compared with unconfined systems. A systematic understanding has remained elusive, especially with respect to background salt concentration and boundary condition effects like the nanopore surface chemistry and the reference state used to calculate free energies. We utilize molecular dynamics simulations along with thermodynamic integration to determine the free energy difference associated with acid-base chemistry in 2 nm and 4 nm slit pores open to a bulk-like reservoir. pKa increases are predicted when confining acetic acid, formic acid, and bicarbonate in the slits at infinite dilution conditions. We find that confinement weakens the acids, and the modulation of outer pore surface dipole magnitudes can tune the pKa shift values, suggesting that purely “intrinsic” electrostatic effect on confinement may not exist. At sufficiently high salt concentrations, the dielectric/electrostatic effects on pKa values diminish due to charge screening effects. These discoveries enable future modifications of nanopore chemistries to achieve desirable properties for industrial applications.

A diagnostic approach of various urethral diseases using multimodal imaging findings: comprehensive overview.

In clinical practice, urethral diseases are not as frequent as conditions affecting other components of the urinary system. Radiological imaging tests, such as retrograde urethrography, CT, MRI, and PET/CT, along with patient history, are crucial for accurately assessing relatively rare urethral lesions. This article aimed to provide a comprehensive overview of urethral lesions, from traumatic changes to neoplasms, and discuss the multimodal imaging findings of various urethral lesions that radiologists should know. To this end, the normal imaging anatomy of the urethra and a step-by-step approach that can be used in clinical practice have been presented to help in the systematic understanding of urethral lesions.

A Systematic understanding of the risk development process for port authority

Ports play a crucial role in the maritime transportation system but are also vulnerable to various risks. In the current complex and uncertain global market, characterized by factors such as the COVID-19 pandemic, the Russia-Ukraine War, climate change, and geopolitics, the development and operation of ports face increasing uncertainties and challenges. These factors have had a significant impact on maritime security worldwide. Previous studies on port risks have primarily focused on the operational phase of ports, lacking a comprehensive view of the whole lifecycle. Little effort has been made to explore the developmental process of risk events within the port environment, leading to a failure to distinguish the causes and results of risks from the risk events. In this study, a meta-case analysis method is employed to examine 208 port cases from 51 countries worldwide, revealing the developmental process of risk events across different phase of port. The innovative findings highlight the periodic pattern of port risks, the critical path of risk development, the unequal distribution of risk initiators and recipients, as well as the co-occurrence effects of various causes. The study provides insights into rethinking port risks and management strategies. It aims to assist international port authorities and researchers in developing a systematic understanding and management approach for risks throughout the whole lifecycle of ports.