Extensive Survey Research Articles

Diversity In N.W. Himalayan Macrofungi (Basidiomycetes) and their Conservation

The diversity and distribution of macrofungi belonging to Jelly fungi, Agaricales, Aphyllophorales and Gasteromycetes in N. W. Himalayas, based on extensive survey and collections of these fungi from this region have been discussed in the present communication. An emphasis is laid to intensify the survey and identification of taxa and habitats worthy of conservation, leading to ascertain the exact status of species. The paper discusses the various threats to which not only the fungi but their habitats are also constantly exposed, and suggests the strategies for their effective conservation. The problems faced in evolving the parameters towards the preparation of Red Data lists/Books on fungi have also been discussed and possible remedies to overcome them are outlined.

Problems and Prospects of Botanical Methods of Mineral Exploration with Reference to India - an Appraisal

The present report attempts to evaluate the existing literature with regard to geobotanical and biogeochemical methods of investigation for mineral prospecting. The emphasis is laid o.i the validity of grouping of indicator plants into 'Universal' and 'Local' in the light of their limitations in application value. The report also stresses the essentiality of biosystematic studies prior to making any new reports from any mineralized areas. This suggestion is made taking in view the prevailing opinions on the evolution and adaptation of indicator plants. Moreover, few notable indicator species are now recognised as only ecotypes of the related species growing on unmineralised areas. A compilation of indicator plants is made and the scope of utilisation and profitable exploitation of these taxa is discussed. A few important aspects of biogeochemistry are also given which are necessary in systematic and effective orientation surveys. It was felt that instead of taking up this subject in the established line, the analysis of herbarium material, procured from different herbaria of the country would be of great use for a quick tracing and assessment of mineral rich areas in the country.

Boom and bust: the effects of masting on seed predator range dynamics and trophic cascades

AbstractAimSpatiotemporal variation in resource availability is a strong driver of animal distributions. In the northern hardwood and boreal forests of the northeastern United States, tree mast events provide resource pulses that drive the population dynamics of small mammals, including the American red squirrel (Tamiasciurus hudsonicus), a primary songbird nest predator. This study sought to determine whether mast availability ameliorates their abiotic limits, enabling red squirrel elevational distributions to temporarily expand and negatively impact high‐elevation songbirds.LocationNortheastern United States.MethodsWe used two independent datasets to evaluate our hypotheses. First, we fit a dynamic occupancy model using data from camera trap surveys to evaluate red squirrel distributional responses to pulses in the tree mast. We also assessed population responses using systematic auditory surveys analysed with an open‐population binomial mixture model. Further, we used modelled red squirrel abundance in nest‐survival models to evaluate whether their abundance is correlated with the daily nest survival of three songbird species.ResultsThe tree mast provided a critical resource pulse that resulted in a two‐fold increase in the annual elevational distribution of red squirrels. The elevational distribution of red squirrels ranged from a minimum of ~450 m (range: 663–1145 m asl) following two consecutive years without a masting event to a maximum of over 1000 m (range: 443–1545 m asl) after a large mast event. The daily nest survival of three songbird species tended to decline with an increase in the abundance of red squirrels.Main ConclusionsTree mast is a central biological phenomenon in many temperate and boreal forests. This study reveals how this resource pulse results in range changes in a small mammal that is both a seed and bird predator, as well as prey for many carnivores. Thus, understanding this phenomenon can inform the conservation and management of northern forests, including breeding songbirds.

Evolving or immutable - phase I solid tumor trials in the era of precision oncology

In the era of precision oncology (PO), systemic therapies for patients (pts) with solid tumors have shifted from chemotherapy (CT) to targeted therapy (TT) and immunotherapy (IO). This systematic survey describes features of trials enrolling between 2010 and 2020, focusing on inclusion criteria, type of dose escalation scheme (DES) utilized, and use of expansion cohorts (ECs). A literature search identified phase I studies in adults with solid tumors published January 1, 2000– December 31, 2020 from 12 journals. We included only studies enrolling between 2010 and 2020 to better capture the PO era. Two reviewers abstracted data; a third established concordance. Of 10,744 studies, 10,195 were non-topical or enrolled prior to 2010; 437 studies were included. The most common drug classes were TT (47.6%), IO (22%), and CT (6.9%). In studies which reported race, patients were predominantly white (61.7%) or Asian (25.7%), followed by black (6.5%) or other (6.1%). Heterogeneity was observed in the reporting and specification of study inclusion criteria. Only 40.1% of studies utilized ECs, and among the studies which used ECS, 46.6% were defined by genomic selection. Rule-based DES were used in 89% of trials; a 3+3 design was used in 80.5%. Of all drugs tested, 37.5% advanced to phase II, while 10.3% garnered regulatory licensure (for an indication tested in phase I). In the era of PO, TT and IO have emerged as the most studied agents in phase I trials. Rule-based DES, which are more relevant for escalating CT, are still chiefly utilized.

Petiole Anatomy and Minor Veins as Aids for the Identification of <I>Symplocos</I> of Nepal

On a study of eleven species of Symplocos occurring in Nepal, it is observed that petiole anatomy and minor venation pattern are helpful for identifying sterile material. Two species, S. pyrifolia and S. sumantia have exactly similar characters but can be distinguished from the other nine species. Sclerenchymatous bundle sheaths are known in a few dicotyledonous families like Winteraceae and Melastomataceae, and in a few genera of Dilleniaceae. It is significant that such sclerenchymatous bundle sheaths are also found in some species of Symplocos. It is felt that extensive survey of all the species of Symplocos would prove to be very interesting.

Non-covalent interactions constructor of 3D networks of Co (II) and Cu (II) complexes with pyridine ligands: systematic theoretical and experimental survey

Non-covalent interactions constructor of 3D networks of Co (II) and Cu (II) complexes with pyridine ligands: systematic theoretical and experimental survey

Rectifying a century of misidentifications: a taxonomic re-evaluation of sipo snakes (Colubridae: Chironius) on Trinidad

The island of Trinidad has several endemic reptile species that in some cases are morphologically indistinguishable, or almost so, from their mainland counterparts. In particular, many snakes from the island have not been examined thoroughly with modern scientific methods and may therefore be misidentified. At least two species of sipo snakes (Chironius carinatus, C. septentrionalis) are reported to inhabit Trinidad, both being considered species already inhabiting the mainland, though their identities are based solely on morphology. Here, we evaluate the molecular distinctiveness of these Trinidadian snakes and assess their relationships to other members of the genus. We constructed a multi-locus data set (12S rRNA, 16S rRNA, cyt b, ND4, cmos, NT3, Rag-1, Rag-2) including novel sequences and those available on GenBank to perform Bayesian and maximum likelihood phylogenetic analyses. Our phylogenetic reconstruction elucidates the identity of both Trinidad species, which have been misidentified since their discovery, and we provide a literature review of their taxonomic history. More specifically, our results suggest that the Trinidad population of Chironius carinatus is an undescribed species, that we describe herein as Chironius nigelnoriegai sp. nov., and is the sister to C. flavopictus. Our results also demonstrate that the Trinidad population previously identified as C. septentrionalis is instead the mainland species C. cochranae, a member of a clade with C. foveatus, C. laurenti, and C. multiventris. Finally, we generated a time tree and inferred that our new species separated from C. flavopictus approximately 4 million years ago in the Pliocene, a time when the island of Trinidad detached from Northern Venezuela. This work contributes to a better understanding of species diversity of Trinidad and we hope that it assists in conservation efforts towards this important endemic region. These findings support the prospect of rapid speciation on Trinidad and implies that more extensive surveys of island squamates will reveal additional cryptic diversity. http://zoobank.org/urn:lsid:zoobank.org:pub:500DB91B-62CD-4051-9831-0BEEAC64C8E2

SURFACE MOBILITY SOLUTION

In the Nagpur City of Maharashtra, the barrier of transportation in the daily life. Amidst mixture of sounds of honking horns and bustling streets, an intricate web of challenges come face to face with drivers and transportation professionals at every turn. As I delved into Nagpur's mobility landscape, engaging with drivers. The journey of exploration began with a simple premise: to understand the quality of being complex mobility challenges from the perspective of those entrenched in the frontline of transportation. Through extensive interviews and surveys, I sought to peel back the layers of complexity surrounding issues that impact drivers' livelihoods, schedules, and overall efficiency. What emerged from these interactions were recurring themes, echoing the sentiments of drivers navigating the labyrinthine streets of Nagpur: Documentation and Permit Predicaments: A maze of paperwork and bureaucratic hurdles often impedes the seamless flow of operations for drivers. From license renewals to permit applications, navigating the labyrinth of documentation requirements proves to be a formidable task, with delays rippling through the fabric of daily operations. Route Riddles: In a city where every turn can make the difference between timely arrival and frustrating delays, the lack of familiarity with optimal routes emerges as a significant challenge. For drivers, deciphering the shortest path from point A to point B is akin to navigating through a complex puzzle, where each intersection presents a myriad of choices, each with its own consequences. time Constraints and Efficiency Dilemmas: In the world of transportation, time is money, and every minute lost to loading and unloading delays translates into tangible losses for drivers. Whether it's waiting in line at a distribution center or grappling with the intricacies of cargo handling, the specter of inefficiency looms large, casting a shadow over the profitability of operations. Technological Turbulence: As the world hurtles towards an increasingly digitized future, the divide between technological proficiency and traditional practices widens. For drivers grappling with the complexities of GPS navigation systems and digital documentation platforms, the learning curve can be steep, posing yet another barrier to efficiency and competitiveness.

Self-tuning Database Systems: A Systematic Literature Review of Automatic Database Schema Design and Tuning

Self-tuning is a feature of autonomic databases that includes the problem of automatic schema design. It aims at providing an optimized schema that increases the overall database performance. While in relational databases automatic schema design focuses on the automated design of the physical schema, in NoSQL databases all levels of representation are considered: conceptual, logical, and physical. This is mainly because the latter are mostly schema-less and lack a standard schema design procedure as is the case for SQL databases. In this work, we carry out a systematic literature survey on automatic schema design in both SQL and NoSQL databases. We identify the levels of representation and the methods that are used for the schema design problem, and we present a novel taxonomy to classify and compare different schema design solutions. Our comprehensive analysis demonstrates that, despite substantial progress that has been made, schema design is still a developing field and considerable challenges need to be addressed, notably for NoSQL databases. We highlight the most important findings from the results of our analysis and identify areas for future research work.

Comprehensive molecular interaction map of TGFβ induced epithelial to mesenchymal transition in breast cancer

Breast cancer is one of the prevailing cancers globally, with a high mortality rate. Metastatic breast cancer (MBC) is an advanced stage of cancer, characterised by a highly nonlinear, heterogeneous process involving numerous singling pathways and regulatory interactions. Epithelial–mesenchymal transition (EMT) emerges as a key mechanism exploited by cancer cells. Transforming Growth Factor-β (TGFβ)-dependent signalling is attributed to promote EMT in advanced stages of breast cancer. A comprehensive regulatory map of TGFβ induced EMT was developed through an extensive literature survey. The network assembled comprises of 312 distinct species (proteins, genes, RNAs, complexes), and 426 reactions (state transitions, nuclear translocations, complex associations, and dissociations). The map was developed by following Systems Biology Graphical Notation (SBGN) using Cell Designer and made publicly available using MINERVA (http://35.174.227.105:8080/minerva/?id=Metastatic_Breast_Cancer_1). While the complete molecular mechanism of MBC is still not known, the map captures the elaborate signalling interplay of TGFβ induced EMT-promoting MBC. Subsequently, the disease map assembled was translated into a Boolean model utilising CaSQ and analysed using Cell Collective. Simulations of these have captured the known experimental outcomes of TGFβ induced EMT in MBC. Hub regulators of the assembled map were identified, and their transcriptome-based analysis confirmed their role in cancer metastasis. Elaborate analysis of this map may help in gaining additional insights into the development and progression of metastatic breast cancer.

Fractal Engineering Integration in Antenna Arrays: A Comparative-review for Advanced Transceiver Systems with 5G/IoT Connectivity

The growing demand for space-efficient antennas compatible with portable electronic gadgets inspired the integration of recursively iterated fractal geometries (characterized by self-similarity, space-filling, and multiband/wideband capabilities) in antenna designs. Therefore, this article conducts an extensive survey on fractal-based single-port and multi-port patch antenna designs with multiband and ultrawideband characteristics for their implementation in 5G/IoT (Internet of Things) devices. The survey begins with a basic overview of fractal geometries and the iterated function system (IFS) technique employed for their generation. Further, it highlights the limitation of multipath fading prevalent in single-port antenna arrays that can be overcome by adopting multiple-input multiple-output (MIMO) technology. The MIMO antenna systems are vital for 5G networks to enhance data transmission rate, network capacity, and system reliability. Apart from these admirable attributes, the closely packed antenna elements in the MIMO configuration result in a severe mutual coupling. To address this limitation, various isolation enhancement techniques developed by distinguished researchers are thoroughly discussed in this article, detailing their merits and demerits. At last, this article portrays diverse band-notch structures integrated into the antenna designs to eradicate the existing interfering narrow bands in the ultrawideband (UWB) spectrum. The underlying reason for conducting this survey is to aid antenna designers and academicians with a thorough knowledge of distinct fractal geometries, various isolation improvement approaches, and band-notch techniques on a single platform, desired for designing 5G/IoT-based antenna systems.

Landscape drives zoonotic malaria prevalence in non-human primates.

Zoonotic disease dynamics in wildlife hosts are rarely quantified at macroecological scales due to the lack of systematic surveys. Non-human primates (NHPs) host Plasmodium knowlesi, a zoonotic malaria of public health concern and the main barrier to malaria elimination in Southeast Asia. Understanding of regional P. knowlesi infection dynamics in wildlife is limited. Here, we systematically assemble reports of NHP P. knowlesi and investigate geographic determinants of prevalence in reservoir species. Meta-analysis of 6322 NHPs from 148 sites reveals that prevalence is heterogeneous across Southeast Asia, with low overall prevalence and high estimates for Malaysian Borneo. We find that regions exhibiting higher prevalence in NHPs overlap with human infection hotspots. In wildlife and humans, parasite transmission is linked to land conversion and fragmentation. By assembling remote sensing data and fitting statistical models to prevalence at multiple spatial scales, we identify novel relationships between P. knowlesi in NHPs and forest fragmentation. This suggests that higher prevalence may be contingent on habitat complexity, which would begin to explain observed geographic variation in parasite burden. These findings address critical gaps in understanding regional P. knowlesi epidemiology and indicate that prevalence in simian reservoirs may be a key spatial driver of human spillover risk.

Landscape drives zoonotic malaria prevalence in non-human primates

Zoonotic disease dynamics in wildlife hosts are rarely quantified at macroecological scales due to the lack of systematic surveys. Non-human primates (NHPs) host Plasmodium knowlesi, a zoonotic malaria of public health concern and the main barrier to malaria elimination in Southeast Asia. Understanding of regional P. knowlesi infection dynamics in wildlife is limited. Here, we systematically assemble reports of NHP P. knowlesi and investigate geographic determinants of prevalence in reservoir species. Meta-analysis of 6322 NHPs from 148 sites reveals that prevalence is heterogeneous across Southeast Asia, with low overall prevalence and high estimates for Malaysian Borneo. We find that regions exhibiting higher prevalence in NHPs overlap with human infection hotspots. In wildlife and humans, parasite transmission is linked to land conversion and fragmentation. By assembling remote sensing data and fitting statistical models to prevalence at multiple spatial scales, we identify novel relationships between P. knowlesi in NHPs and forest fragmentation. This suggests that higher prevalence may be contingent on habitat complexity, which would begin to explain observed geographic variation in parasite burden. These findings address critical gaps in understanding regional P. knowlesi epidemiology and indicate that prevalence in simian reservoirs may be a key spatial driver of human spillover risk.

Novice School Leaders’ Turnover Intentions: The Role of Working Conditions and Organizational Factors

Purpose: This study aimed to explore the relationship between the psycho-social working conditions of novice school leaders and their turnover intentions, focusing on potential variations across public- and private schools and school levels. Research Methods: We invited all novice school leaders (n = 3,389) enrolled in the in-service Swedish Principal Training Program to participate in an extensive survey, with a 65% (n = 1,998) response rate. The survey investigated turnover intentions, working conditions, prerequisites, and organizational ambiguity. The collected survey data, in combination with official data, were analyzed using ANOVA's to identify differences across actors and school levels, and linear regressions to investigate factors explaining turnover intentions. Findings: The findings revealed higher turnover intentions among public school leaders compared to private school leaders. This was attributed to differences in prerequisites and organizational ambiguity. All novice school leaders exhibited similar patterns regarding factors strongly associated with turnover intention, despite actor and school level affiliation. Specific levels of demand, autonomy, and support combined, predicted turnover intentions among novice school leaders with notable accuracy. Implications for Research and Practice: The study has profound implications for stakeholders in the educational system striving to decrease novice school leader turnover. Providing adequate working conditions emerges as a key factor for nurturing and retaining school leaders from the novice pool, offering insights into strategies for managing leadership transition in schools.

Bioanalytical Method Development and Validation and forced degradation of Sitagliptin and determination of Pharmacokinetic application study in Human Plasma by RP-HPLC method

In the present investigation, an attempt was made for the development, validation, forced degradation and pharmacokinetic application of sitagliptin in the human plasma spiking studies by UV - HPLC method. The experimentation was developed based on the extensive literature survey and ascertained by the statistical parameters of the sampling. A simplified, accurate method was created by the liquid chromatographic system from Shimadazu LC 20AD consisting of manual injection. The optimized chromatogram was obtained with acetonitrile in the isocratic mobile phase method at a 1.0 mL/min flow rate. A thermo C-8 column (4.6X250mm,5μm) was used as a stationary phase, and 265.0nm was selected as the detection wavelength with the aid of a UV-Vis detector. The proposed method was validated as per ICH guidelines. The technique was linear in the range of 10-50μg/mL with correlation coefficient R2 = 0.9746, respectively. Recovery studies postulated that % RSD 19.14, 3 & 9.95 respectively. Injection repeatability values were found to be % RSD 17 & 10.63 for intraday and interday, respectively. Stress degradation studies revealed that sitagliptin degrades more rapidly when subjected to 0.1 NaoH. Human plasma spiking studies reported 3.02 ng/mL at 3.02+/-60 min of C and T max, respectively. Keywords: Sitagliptin, Method development, HPLC, Validation, Stress degradation studies, Human plasma spiking studies

A novel proposed classification system for rock slope stability assessment

The present study introduces “rock slope instability score (RSIS)” a novel classification system for assessing rock slope stability. It takes into account geological and geotechnical parameters, as well as the impact of human activities and triggering parameters, which have become more frequent due to climate change and few of them have been ignored in existing classifications. The study focuses on rock slopes of various lithologies from the Indian Himalayas. The development of this new classification system is based on the examination of 81 different rock slopes from various states of the Indian Himalayas. Extensive field surveys, rock sampling, geotechnical laboratory tests, and ground measurements have been conducted at the various slope sites to establish a comprehensive scoring system for the stability assessment. The distributions of weightage to each parameter have been considered, corresponding to its degree of impact in causing slope instability. Sensitivity analysis of all defined parameters of RSIS system has revealed that the majority of the parameters exhibit a strong positive correlation, with Pearson correlation coefficients ranging from 0.74 to 0.61. However, two parameters, namely discontinuity dip and the relationship between slope & discontinuity direction, gives moderate relationship with correlation coefficient values of 0.48 and 0.41, respectively. To avoid any designer biasness in the system, several individuals gathered data set at different times. The proposed classification system has demonstrated a strong correlation with the actual slope condition, and it is quite promising. The outcome of RSIS classification for studied 81 slopes classified 2 slopes under stable condition, 21 slopes as partially stable, 44 as unstable, and 14 as completely unstable.

A Systematic Survey of Deep Learning-Based Single-Image Super-Resolution

Single-image super-resolution (SISR) is an important task in image processing, which aims to enhance the resolution of imaging systems. Recently, SISR has made a huge leap and has achieved promising results with the help of deep learning (DL). In this survey, we give an overview of DL-based SISR methods and group them according to their design targets. Specifically, we first introduce the problem definition, research background, and the significance of SISR. Secondly, we introduce some related works, including benchmark datasets, upsampling methods, optimization objectives, and image quality assessment methods. Thirdly, we provide a detailed investigation of SISR and give some domain-specific applications of it. Fourthly, we present the reconstruction results of some classic SISR methods to intuitively know their performance. Finally, we discuss some issues that still exist in SISR and summarize some new trends and future directions. This is an exhaustive survey of SISR, which can help researchers better understand SISR and inspire more exciting research in this field. An investigation project for SISR is provided at https://github.com/CV-JunchengLi/SISR-Survey.

Caracterização, compactação e CBR (ISC), pelo Método DIRENG-ME-01/87, realizado em Latossolo típico do Centro-Oeste Brasileiro para uma área no Aeroporto Internacional Presidente Juscelino Kubitschek, Brasília / Distrito Federal

This work presents field and laboratory geotechnical studies, with emphasis on compaction tests according to the recommendations of the Test Method for Airport Infrastructure Works (AASHTO Method) and California Bearing Ratio (CBR) tests, with the aim of determining the CBR using the DIRENG-ME-01/87 method for subgrade material, which takes into account the CBR corresponding to 95% of the dry specific mass compacted at the Modified Proctor energy, resulting from the composition of the graph of the three compaction energies (normal, intermediate and modified). The study involved an extensive bibliographical survey, field and laboratory work with geotechnical tests, as well as the appropriate processing of the results obtained. The studies showed that the soils have visual tactile characteristics with a predominance of latosol type sandy-silty clay to red sandy-silty clay. In addition, classification by the Unified Soil Classification System (SUCS) showed a predominance of low plasticity silt (ML), but also by TRB (HRB) a predominance of clayey soils (A-7-5). The CBR values using the DIRENG-ME-01/87 method for the 18 samples studied ranged from 8.1% to 9.0%, with an average value of 8.7%, representing 61% of the average CBR value of the modified energy, which was 14%.

Food ethnobotany of forest resource in the high-altitude Himalaya Mountains: Enhancing the food sovereignty of ethnic groups

The vital knowledge of traditional foraging techniques used in indigenous peoples' cuisines may be preserved through gastronomical field studies before it is lost forever. Certain plants are appreciated for their gastronomic, social, economic and ecological importance in the High Himalaya because they play such a significant role in the daily life of the local indigenous populations. To determine the plant cultural indicators for each ethnic group, the data were analyzed using an indicator species analysis. Semi-structured interviews of 167 participants, focus group discussion, and field observations were used to gather information from February 2019 to August 2022 for a comprehensive and systematic gastronomical survey. Across four ethnic groups, a total of (N = 99) wild edible plant species and (N = 9) fungi species from 38 families were documented. Tender leaves were the most commonly used, while tubers were the least commonly used. The majority of the species reported were used as vegetables, followed by species used as fruits and herbal tea. For the first time, we examined cross-cultural similarity and dissimilarity for gastronomic usage: vegetables and savoring plants,fruits, and herbal tea across the cultures studied from the perspective of food ethnobotany. We discovered a clear difference in how different cultures used forest resources, with Gujjar and Pahari showing the most species similarity. This is because these ethic groups are culturally linked with one another and share a common social structure, geography, and language. We calculated plant cultural markers for each species, and 19 of them had significant p-values among the four ethnic groups. The findings revealed a positive relationship between the Gujjar and Pahari ethnic groups and the gastronomical indicator values, while the Kashmiri ethnic group had a negative relationship. The Kashmiri ethnic group experienced the loss of traditional knowledge because of the economic transition that caused people to prefer purchasing vegetables from the market rather than foraging for them in the wild. Traditional knowledge was also dwindling between the Gujjar and Pahari ethnic groups because of social changes brought on by developmental activities that changed their way of life. The identified plant cultural markers were significant to local residents and frequently had adaptations to extremely harsh climatic and environmental conditions. Our finding that 47% of species had market value suggests that these species have a sizable market demand and a promising economic value. They have the potential to boost food security, local community sovereignty, and people's living standards. Food production systems may become more resilient and sustainable by incorporating these indicator species into conventional agriculture. The current study raises awareness about forest resources and enables ethnic groups to live in a natural environment without food scarcity.

A large case-control study indicates a breed-specific predisposition to feline tooth resorption

Tooth resorption (TR) is one of the most common dental diseases of cats. It is a painful condition leading to tooth loss. The etiology of TR remains unclear, but old age, breed, other oral and dental diseases, and environmental factors are suspected predisposing factors. In our study, we used part of the data from the extensive feline health online survey of 8115 Finnish cats. As TR is difficult to detect and as the feline health survey included diagnoses defined by both veterinarians and the owners, we limited our study to a subpopulation of cats diagnosed with oral or dental disease by a veterinarian and had dental examination or surgery under sedation (n=944). We utilized case-control study analysed by multivariable logistic regression to determine the risk factors and breed variation of feline TR. The 202 cats diagnosed with TR were defined as TR cases and the remaining 742 cats as controls. The frequency of veterinarian-diagnosed TR was 3.9% in the health survey data (316/8115) and 21% in the subpopulation (202/944). The risk of TR increased with age (14.7% in youngest and 25.3% in oldest age group). Our finding that TR was significantly associated with gingivitis or periodontitis in cats that had also calculus (OR: 2.49 and 3.70, respectively) suggests that inflammatory changes caused by calculus increase the risk of TR. We found that Cornish Rex, European, and Ragdoll are at higher risk for TR (OR: 2.44, 2.98 and 2.90, respectively). Exotic-Persians breed group had lower risk (OR: 0.28). TR was not observed in Turkish van or Devon Rex. The differences between breeds highlight a genetic contribution. In addition, female cats that had food available constantly had significantly less TR than female cats that had feeding times (OR: 0.44). The underlying reasons for this remain unexplained in our study.